A Qualitative Study on the Psychological Experience of Pregnant Women with Abnormal Induced Abortion of Fetuses under 20 Weeks of Pregnancy

Objective: This paper aims to understand the psychological experience and needs of pregnant women who need induction of labor due to fetal abnormalities at less than 20 weeks of gestation through in-depth interviews. Methods: Using the phenomenological research method in qualitative research, 12 pregnant women with fetal abnormalities less than 20 weeks of gestation in the obstetrics department of a hospital from January to April 2023 were selected as the research objects for semi-structured in-depth interviews. After information was collected to saturation, Colaizzi content analysis method was used to sort out, analyze and refine the data. Results: Through the interview results, three themes were refined from the transcript. Those are: 1) the support and assistance needed during the induction of labor;2) inner feelings after labor induction;3) The vision of future life. Conclusion: Abnormal fetal development at <20 weeks of gestation can cause anxiety, depression, guilt, loneliness and other negative emotions for pregnant women, and they need to get corresponding psychological support, especially during the period from fetal abnormality to induction of labor, pregnant women have to experience many physical and mental suffering, and need to get the care of family, relatives, friends, medical staff and society. Medical staff can help them seek multi-directional support, provide professional knowledge, and help them with self-management.

孕20～24周对子痫前期有预测作用的血清学标志物的Logistic研究

目的探讨1 h血沉(ESR1)、血色素(Hb)、红细胞压积(HCT)、血小板计数(PLT)及血小板平均体积(MPV)在孕20～24周是否可以对子痫前期起到预测作用。方法选取孕20-24周孕妇共计352例,其中66例子痫前期患者为病例组,286例正常孕妇为对照组,采用单因素及多因素分析方法进行病例对照研究,比较ESR1、Hb、HCT、PLT及MPV等的差异,寻找该孕期对子痫前期有预测作用的血清学标志物。结果采用单因素分析,病例组和对照组的Hb、HCT、MPV之间的差异有统计学意义(P均<0.05)。采用多因素分析,Hb、MPV为子痫前期患者的临床危险因素(P均<0.05)。结论孕20～24周,Hb、MPV对子痫前期有一定的预测作用。

心理干预联合盐酸利托君与硫酸镁治疗孕20周后先兆流产的效果观察

目的 研究分析心理干预联合盐酸利托君与硫酸镁治疗孕20周后先兆流产的效果观察。方法 选取浙江省杭州市红十字会医院2015年2月-2016年10月收治的100例孕20周后先兆流产孕妇为研究对象,随机分为对照组和实验组,每组患者各为50例。对照组患者给予硫酸镁治疗;实验组患者给予盐酸利托君治疗,给予心理干预,关注患者心理健康,加强与患者交流与沟通。结果 经过相应的治疗后,实验组SAS评分为（40.1±6.2）分,SDS评分为（38.4±7.9）分。对照组患者SAS和SDS评分分别为（49.6±7.2）分、（48.2±8.5）分。治疗后,实验组患者中5例出现不良反应,不良反应发生率为10.0%。对照组患者中13例出现不良反应,对照组不良反应发生率（26.0%）显著高于实验组患者（10.0%）,差异具有统计学意义（P〈0.05）。实验组患者新生儿体质量、妊娠延长时间以及药物起效时间均优于对照组,差异具有统计学意义（P〈0.05）。结论 心理干预联合盐酸利托君与硫酸镁治疗孕20周后先兆流产的临床效果较好,能够显著改善患者的抑郁以及焦虑情绪,具有临床进一步推广和应用的意义。

米非司酮配伍米索前列醇用于13～20周孕引产的效果观察

目的:探讨13～20周妊娠引产中使用米非司酮联合米索前列醇与单用利凡诺引产的疗效。方法:选择1998～1999年本院收治妊娠13～20周利凡诺引产者100例和2004年1月～2006年12月收治妊娠13～20周米非司酮联合米索前列醇引产者100例,对其引产效果作回顾性对比分析。结果:13～20周中期妊娠者,使用米非司酮联合米索前列醇较单独用利凡诺引产引产成功率高,总产程时间短,产后出血量少,胎盘、胎膜残留率差异无显著性。结论:l3～20周中期妊娠者,使用米非司酮配伍米索前列醇引产比较安全,效果好。