电针治疗慢性非细菌性前列腺炎32例

慢性非细菌性前列腺炎（CNP）是青壮年男性最常见的泌尿系统疾病之一,严重影响患者生活质量和身心健康。有资料显示约有50%的男性在一生的某个时期会受到前列腺炎的影响[1]。自2008年6月至2009年4月,我们运用电针方法治疗慢性非细菌性前列腺炎,收到较好疗效,结果报道如下。

电针治疗血管性痴呆92例

目的:研究针刺及中西医结合治疗血管性痴呆患者的疗效。方法:符合纳入标准的182例患者随机分为治疗组92例和对照组90例,两组均给予常规认知训练及口服尼莫地平,治疗组还给予电针(四神聪、百会、本神、风池、人中、足三里等穴),并分别在治疗前和治疗6周后给予LOTCA和FIM评定。结果:治疗组在认知功能、日常生活能力、主观总体印象方面均较对照组有明显改善(P<0.05),治疗组疗效好于对照组。结论:对血管性痴呆患者及时给予电针治疗可起到益气活血、健脾祛痰、补脑益髓、醒神开窍之功。

音乐电针疗法对脑出血大鼠血肿周围脑组织SODI活力及形态学的影响

目的:探讨音乐电针疗法对脑出血大鼠血肿周围脑组织SOD活力及形态学的影响。方法:采用胶原酶加微量肝素尾状核注射诱导大鼠脑出血模型,随机分为空白组、模型组、药物组、针药组,评估各组大鼠神经功能缺损情况,测定各组大鼠脑组织SOD活力及观察其脑组织病理形态的改变。结果:14d后各造摸组大鼠神经功能缺损都有一定程度的恢复,治疗组较模型组恢复好,两组比较差异显著(Longa法P<0.05,);脑组织SOD活力测定显示药物组与针药组均较模型组有所提高,具有统计学意义(P<0.05,P<0.01),药物组与空白组相比有统计学意义(P<0.05),针药组与空白组无统计学意义(P>0.05)。结论:音乐电针疗法具有促进脑出血模型大鼠的神经功能缺损恢复,提高其脑组织SOD活力,减轻其脑组织病理损伤,增强其抗自由基损伤的能力及促进损伤修复的功能。

电针治疗血管性痴呆35例脑电图观察

目的:探讨血管性痴呆患者经电针治疗的脑电图临床效果。方法:选取70例血管性痴呆患者作为研究对象,随机分为研究组和对照组。对照组给予尼莫地平治疗,研究组给予电针治疗。观察两组治疗前后脑电图的变化。结果:血管性痴呆患病情程度与脑电图异常程度间存在正相关关系,痴呆程度越严重,脑电图异常改变就越显著;两组治疗后,α波频、α波幅、波频均高于治疗前,波幅低于治疗前,且研究组患者α波频、α波幅均高于对照组,波幅低于对照组,上述差异均具有统计学意义。结论:脑电图可反映血管性痴呆患者的病情程度,电针治疗血管性痴呆可有效改善患者的脑电图,效果优于尼莫地平。

低温等离子髓核消融成形术联合电针夹脊穴治疗腰椎间盘突出症疗效观察

目的：观察低温等离子射频消融髓核成形术联合电针夹脊穴治疗腰椎间盘突出症的临床疗效。方法：选取在我院确诊为腰椎间盘突出症并经低温等离子髓核消融成形术联合电针夹脊穴治疗,术后随访时间6~9个月,平均6.5±5.3个月,收集患者术前、术后第1天及术后2周、术后6个月VAS评分、JOA评分及优良率（改良Macnab标准）,并对上述资料进行统计学分析。结果：术前、术后第1天、术后2周、术后6个月患者VAS评分分别为7.17±0.80、3.65±0.99、2.47±0.79、2.10±0.98,对应时间患者JOA评分分别为13.15±0.85、18.29±2.80、20.34±2.37、23.02±2.07;术后各时点VAS评分与术前对比,差异均有统计学意义,术后2周与术后1天VAS评分对比,差异有统计学意义,术后6个月与术后2周VAS评分对比差异显著,JOA评分亦同;按照改良Macnab评估标准,术后第1天、术后2周、术后6个月优良率分别为75.6%、87.8%、90.2%。结论：低温等离子髓核消融成形术联合电针夹脊穴治疗腰椎间盘突出症,操作简便、安全、并发症少、近期疗效较好。

绝缘电针治疗面瘫60例

目的:观察绝缘电针治疗面瘫的疗效。方法:100例患者,随机分为治疗组60例,对照组40例,治疗组使用“绝缘电针”进行治疗,取穴颊车和地仓;阳白和下关,用“绝缘电针”断续波治疗,对照组用药物治疗。结果:治疗组60例总有效率100%,对照组40例总有效率95%(P<0.01)。提示:“绝缘电针”疗法能选择性作用于受累的主要经脉,使其气血通畅,又能防止电流对正常组织的刺激及损伤,对面部神经功能有即时的良好调节作用,促进血液循环,改善局部营养代谢,增加肌纤维的收缩,使炎症渗出物得到吸收。

变频电针治疗胆石症的临床观察

目的:探求治疗胆石症疗效显著、安全实用的方法。方法:120例患者随机分为两组,治疗组取右侧的期门、梁门、日月、胆俞、肝俞、阳陵泉、胆囊穴,给予变频电针治疗;对照组依次给予中药排石汤、33%硫酸镁40mL、0·5%盐酸30mL及脂餐,做推按运经仪治疗,观察两组临床疗效。结果:治疗组总有效率为86·7%,对照组总有效率为68·3%。两组疗效比较,统计学处理,P<0·05,差异有显著性意义,说明治疗组疗效明显优于对照组。结论:变频电针疗法疗效肯定,较总攻排石疗法具有优势。

Suppressing Leakage Currents and Improving Performance of Indoor Organic Photovoltaic Devices

Organic photovoltaic(OPV) devices hold great promise for indoor light harvesting,offering a theoretical upper limit of power conversion efficiency that surpasses that of other photovoltaic technologies.However,the presence of high leakage currents in OPV devices commonly constrains their effective performance under indoor conditions.In this study,we identified that the origin of the high leakage currents in OPV devices lay in pinhole defects present within the active layer(AL).By integrating an automated spin-coating strategy with sequential deposition processes,we achieved the compactness of the AL and minimized the occurrence of pinhole defects therein.Experimental findings demonstrated that with an increase in the number of deposition cycles,the density of pinhole defects in the AL underwent a marked reduction.Consequently,the leakage current experienced a substantial decrease by several orders of magnitude which achieved through well-calibrated AL deposition procedures.This enabled a twofold enhancement in the power conversion efficiency(PCE) of the OPV devices under conditions of indoor illumination.

Micro-galvanic corrosion behaviour of Mg-(7,9)Al-1Fe-xNd alloys

The localized micro-galvanic corrosion process and the kinetic information of Mg-(7,9)Al-1Fe-x Nd alloys were investigated by in situ observation under electrochemical control and in situ atomic force microscopy(AFM)in an electrolyte environment.The results revealed that the formation of the Nd-rich phase in alloys resulted in a decrease in the Volta potential difference from~400 m V(AlFe3/α-Mg)to~220 mV(Nd-rich/α-Mg),reducing the corrosion products around the cathodic phase and corrosion current density of the microscale area.The addition of Nd significantly improved the corrosion resistance,mainly due to the suppression of the micro-galvanic corrosion between the second phases and substrate.Finally,the corrosion mechanism of Mg-(7,9)Al-1Fe-x Nd alloys was discussed based on in situ observations and electrochemical results.

CLINICAL STUDY ON THE TREATMENT OF POST-STROKE DEPRESSION WITH ELECTROACUPUNCTURE OF “NIWAN BAZHEN” POINTS

Objective To observe the therapeutic effect of electroacupuncture （EA） of ＂Niwan Bazhen＂ points in the treatment of post-stroke depression. Methods A total of 66 post-stroke depression patients were randomized into treatment group （EA＋oral administration of Prozac-20, n =31 ） and control group （o- ral administration of Prozac-20, 20 mg/d, 28 days altogether, n =30）. For patients of treatment group, EA （2/100 Hz, a tolerable stimulation strength） was applied to ＂Niwan Bazhen＂ points [Baihui （百会 GV20）, etc. ] for 30 min, once daily, （except weekends） continuously for one month. Halmiton Rating Scale （HAMD） for Depression and Chinese Scale for Stroke （CSS） were used to evaluate the therapeutic effect. Results After the treatment, of the 30 and 31 cases in control and treatment groups, 4 and 6 were cured, 10 and 14 experienced marked improvement.in their symptoms, 6 and 7 had an improvement, 6 and 4 failed, with the cure＋ markedly effective rates being 46.7% and 64.5% respectively. The therapeutic effect of treatment group was significantly superior to that of control group （ P〈0.05）. The decreased values of both HAMD and C,,SS of treatment group were remarkably lower than those of control group （P〈0.01,0.05） . Conclusion EA of ＂Niwan Bazhen＂ points is an effective remedy for post-stroke depression.

ADVANCES OF STUDIES ON MECHANISMS OF ELECTROACUPUNCTURE ANALGESIA

The relative reports on the effects of electroacupuncture （EA） on the nervous system and neuro- transmitters, tolerance of EA and so on in recent years are reviewed so as to reveal the analgesic mechanism of EA and provide reference for clinical researches and application of EA.

STUDY ON THE ATTACK CONTROL ACTION OF ELECTRO-ACUPUNC-TURE ON T■IYANG(太阳EX-HN5)FOR MIGRAINE DUE TO HYPERAC-TIVITY OF LIVER YANG:RANDOMIED CONTROLED TRIAL

Objective To discuss the difference of electro-acupuncture and drug in controlling the attack of migraine due to hyperactivity of liver yang. Methods Three-centered random control method was used, and 300 qualified cases were randomly divided into treatment group （146 cases according to the design） and control group （140 cases）, which were respectively treated with electro-acupuncture and drugs （Compound Aminopyrine Phenacetin Tablets, Ergotamine Caffeine Tablets, Diazepam Tablets）, and observed the overall effect and scores of headache, accompanying symptoms, psychological and social adaptability scores, life quality scores, TCM symptoms scores and follow-up results before and after the treatment. Results In treatment group, the successful rate of attack control was 47.3 %, the improvement rate was 73.3 %, and the total effectiveness was 90.4 %, the clinical control rate and improvement were much superior to control group （the clinical control rate 35.7 %, improvement 61.4 %, the total effectiveness 85. 7 % ）, P〈0. 01, the difference in effect was mainly reflected in patients with moderate severity; the total scores of TCM syndrome after the treatment was obviously significant or very obviously significant（ P〈0. 05, P〈0. 01 ）, but the headache scores between two groups was not obviously significant（P〉0.05）, the difference in accompanying symptoms was significant（ P〈0. 01 ） ;the long term attack control action in two groups was not satisfactory, the recurrence was similar （P〉0. 05） ,the severity of headache in recurrence cases of treatment group was alleviated and superior to control group（ P 〈 0. 01 ）, the occurrence of headache after the treatment is much less than that before the treatment and the situation after 2 months was superior to control group （P〈0. 01 ）. Sleepiness and redness of face in some patients which were seen in control group weren＇t seen in treatment group. Conclusion Electro-acupuncture on Tàiyáng （太阳 EX-HN5） can control the attack of migraine due to hyperactivity of liver yang, and it has advantages in improving the accompanying symptoms and reducing the toxic and side effects of western drugs.

CLINICAL REPORT ON MULTI-CENTER RANDOMIZED CONTROLLED TRIAL OF TREATMENT OF MIGRAINE BY ELECTRO-ACUPUNCTURE AT QI■X■(丘墟GB40)

Objective To observe the therapeutic effect of electro acupuncture at QIǖXǖ（丘墟GB40） for treating migraine and provide clinical study for Acupoints Dictionary of People＇s Republic of China. Methods Multi-center （3 First-Class hospitals） study was adopted, and the involved 3 hospitals did clinical observation according to the requirements of the project. The methods are as follows. All cases were randomized into treatment group and control group according to their sequence. QIǖXǖ（丘墟GB40） was selected in treatment group, while Tiānshū （天枢 ST25） was selected in control group. Both groups were performed electro acupuncture, and syndromes indexes of migraine and 5-HT were observed before and after treatment. All data were analyzed by statistic software SPSS11.5. Results There was significant difference of VAS margin between two groups in each center and the combined center （u= -3. 362, P=0. 001 ）. There was significant difference of therapeutic effect of 4-week treatment between two groups in each clinical center and the combined center. The therapeutic effect of 3-month treatment between two groups in No. 1 and No. 3 hospitals, showed significant difference, the treatment group was better; while that of No. 2 hospital had no obvious difference. The therapeutic effect of 6-month treatment between two groups in each center and the combined center had significant difference, the treatment group was better. Conclusion The therapy of electro acupuncture at QIǖXǖ（丘墟GB40） is effective for migraine.

IMPACTS OF PENETRATION THERAPY WITH HEAD ELECTRICAL ACUPUNCTURE ON PROLIFERATION OF NEURAL STEM CELLS IN SUBSTANTIA NIGRA OF RAT MODEL OF PARKINSON'S DISEASE

Objective To probe into the function mechanism of penetration therapy with head electrical acupuncture on Parkinson＇s disease. Methods Microinjection of 6-hydroxydopamin （6-OHDA） on the left cor- pus striatum was adopted to prepare rotation model of Parkinson^s disease in rat. Penetration therapy with head electrical acupuncture was administered in treatment. Normal group, sham-operation group, model group and penetration therapy group were set up. （1）lmmunohistochemical （IHC） method was used to test the morphology and count of positive cell of tyrosine hydroxylase （TH）. （2）RT-PCR technology was used to detect the expression of nestin mRNA of neural stem cell （NSC）. Results （1）Compared with model group, in pene- tration therapy group, the expressions of TH-positive neurons in immune response were increased in areal density （AD）, numerical density （ND） and integrating optic density （P〈0.05）. （2）Compared with model group, in penetration therapy group, the expression of nestin mRNA was increased （P〈0. 05）. Conclusion Penetration therapy with head electrical acupuncture promotes the proliferation of endogenous neural stem cells in substantia nigra of rat model of Parkinson＇s disease.

EFFECT ON BLOOD CLOTTING AND FIBRINOLYSIS WITH ELECTRO-ACUPUNCTURE TREATMENTS AT "BAIHUI" AND "SHUIGU" ACUPOINTS FOR CEREBRAL INFARCTION IN RATS

Objective To investigate the effective mechanism of the treatments with electroacupuncture （EA） at ＂BǎiHuì＂ （GV20） and ＂ShuǐGōu＂ acupoints for cerebral infarction. Methods Forty rats were randomly divided into four groups as normal group （n = 10）, sham-operation group （n = 10）, model group （n = 10）, EA group （n = 10）. The acute cerebral infarction model in rats was developed by blocking the middle cerebral artery with an intraluminal thread. The contents of t-PA,PAI-1 ,D-D and Fib were estimated in each group. Results The contents of t-PA, PAI-1, D-D and Fib increased significantly （P〈0.01） in the model group as compared to the normal and sham-operation group. The contents of t-PA, PAI-1, D-D and Fib decreased significantly （P〈0.05-0.01） in the EA group as compared to the normal group. Conclusion The balance function of blood clotting and fibrinolysis were good and the cerebral abnormal blood was improved in EA group.

EFFECTS OF ELECTROACUPUNCTURE ON EXPRESSION OF INTERCELLULAR ADHESION MOLECULE-1 IN THE RAT OF LOCAL CEREBRAL ISCHEMIA-REPERFUSION

Objective To investigate effects of electroacupuncture （EA） on expression of intercellular adhesion molecule-1 （ICAM-1） in the rat of local cerebral ischemia-reperfusion. Methods Eighty SD rats were randomly divided into a normal control group, a sham operation group, a model group and an EA treatment group, 20 rats in each group. The thread-obstruction method was used for preparation of ischemia-reperfusion model. Zea-Longa rating criteria were used for evaluation of nervous function disorder; Immunohistochemical SABC method was used for detection of ICAM-1 expression in the microvascular endothelial cell of the ischemic brain region, and ELISA method for the soluble ICAM-1 （slCAM-1） content in peripheral blood. Re. suits After cerebral ischemia-reperfusion, both ICAM-1 expression level in the microvascular endethelium cell of the ischemic brain region and slCAM-1 content in the peripheral blood significantly increased in the model group as compared with the normal group and the sham operation group （P〈0.01）; After EA treatment, the ICAM-1 expression level in the microvascular endothelial cell of the ischemic brain region and slCAM-1 content in the peripheral blood were significantly down-regulated in the EA treatment group as com- pared with the model group （P〈 0.05）. Conclusion After cerebral ischemia-reperfusion, the microvascular endothelial cell of the ischemic brain region releases ICAM-1, which induces inflammatory injury of cerebral tissues; EA treatment can decease the expression of ICAM-1, so as to prevent the brain from the injury.

Study on regulatory effect of acupuncture on rotation induced gastric dysrhythmia in rabbits *

AIM A model of experimental gastric dysrhythmia in rabbits was set up to evaluate the effect of different acupoints on regulating the gastric dysrhythmia in rabbits as to promoting the acupuncture treatment for this kind of disease.

EFFECT OF ACUPUNCTURE ON POST-OPERATIVE FUNCTIONAL RECOV-ERY IN PATIENTS WITH LUMBAR INTERVERTEBRAL DISC PROTRUSION

Objective To observe the influence of acupuncture on the post-operative rehabilitation in patients undergoing vertebral pulp extraction due to lumbar intervertebral disc protrusion （LIDP） so as to evaluate its efficacy in the treatment of lumbago induced by LIDP. Methods A total of 69 patients undergoing vertebral pulp extraction were randomized into acupuncture group （ n = 35） and control group （ n = 34）. Patients of acupuncture group were treated with routine rehabilitation method and electroacupuncture （EA） stimulation on Zhìbiān （秩边 BL54） and Wěizhōng （委中 BL40）, acupuncture on Shènshū （ 肾俞 BL23）, Dàchángshū （大肠俞 BL25）, BL54, BL40, Jiájǐ （夹脊 EX-B 2）, Shàngliáo （上髎 BL31）, etc., and cupping on BL40, with 15 days being a therapeutic course and for average 7. 36 courses. Patients of control group were treated with simple rehabilitation method. Functional recovery state was judged before and after surgery by using the standards of Japanese Orthopedic Association （JOA）. Results The average recovery rates of 3 months, 6 months and one year after surgery were 49.93% ,90.31% and 95.08% separately in acupuncture group, and 26.24% ,63.42% and 71.36% successively in control group. The recovery rates of acupuncture group were significantly higher than those of control group at the same time-points （P〈0. 05）. Conclusion Acupuncture has a definite effect on promoting post-operative functional recovery in LIDP patients undergoing vertebral pulp extraction and spinal fusion.

PROTECTION OF ELECTROACUPUNCTURE ON HIPPOCAMPAL INJURY INDUCED BY QUINOLINIC ACID IN RATS

Objective To probe into the protective mechanism of electro-acupuncture （EA） on anti-oxygen stress in dementia-model rats. Methods A total of 30 male SD rats of cleaning grade were randomized into three groups, named sham-operation （n = 10）, model （n = 10）, model＋ EA （n = 10）. The dementia-model rat was made with hippocampal GA1 lesions by quinolinic acid （QA）. On the second day of modeling, in model＋ EA group, EA （3 Hz, 2-4 mA, continuous waves） was applied to ＂Dàzhuī＂ （大椎 GV 14） and ＂Shènshū＂ （肾俞 BL 23） for 10 min. The capability of learning and memory was evaluated by step-down test to observe the changes of nitric oxide （NO）, nitric oxide synthase （NOS） activity, superoxide dismutase （SOD） activity and malondialdehyde （MDA） of the hippocampal tissues in rats separately by biochemical methods. Results EA improved learning and memory of dementia rats with hippocampal CA1 lesions induced by QA at different degrees. It significantly increased SOD activity, reduced MDA content and improved NO level and NOS activity. Conclusion EA improves significantly the learning and memory of the dementia rats due to hippocampal CA1 lesions induced by QA, which is probably relevant with the anti-oxygen stress of EA.

FORTY-EIGHT CASES OF ACUTE GOUTY ARTHRITIS TREATED COMPREHENSIVELY WITH ELECTROACUPUNCTURE AND WARMING MOXIBUSTION

Objective To probe into the effects on acute gouty arthritis treated comprehensively with electroacupuncture (EA) and warming moxibustion. Methods 70 cases were randomized into treatment group (48 cases), in which the EA+warming moxibustion was applied; and controlled group (22 cases), in which, colchicine was prescribed for oral administration. Results The statistical outcomes after 1 course treatment in treatment group: 28 cases were cured (58.33%), 18 cases improved (37.50%) and the total effective rate was 95.83%. In controlled group: 12 cases (54.55%) were cured, 8 cases improved (36.36%) and the total effective rate was 90.91%. The therapeutic effects of two groups were basically consistent, without significant different (P>0.05). But, concerning to side effect, there was no any toxic side effects in the group treated with EA+warming moxibustion, and the occurrence rate in the group treated with colchicine was 40.91%. Conclusion Electroacupuncture+warming moxibustion achieves good therapeutic effects without any side effects.