扩张型心肌病伴心衰患者跨壁复极离散度分析

目的:探讨扩张型心肌病患者体表心电图QT间期、QTpeak、Tp-e(从T波顶点向等电位线作垂线的交点到T波终点的时限)的变化,探讨其可能的临床意义。方法:依据病史、症状、体征、X线及心脏超声,入选扩张型心肌病,心功能均为～级(NHYA分级)的患者72例;对照组为同期门诊健康查体者共有65例。行常规十二导联心电图检查,测量QT间期、QTpeak与Tp-e,采用Bazzett′s校正公式QTc=QT/RR1/2,QTpeakc=QTpeak/RR1/2,T(p-e)c=QTc-QTpeakc得出QTc、T(p-e)c及T(p-e)c/QTc值。Tp-e是目前唯一可从心电图间接反应TDR的指标。结果:与健康对照组比较,扩张型心肌病患者十二导联心电图QTc、T(p-e)c(TDR)及T(p-e)c/QTc明显增大。结论:扩张型心肌病患者QTc、T(p-e)c及T(p-e)c/QTc增加。

Investigation on Non-covalent Complexes of Cyclodextrins with Li＋ in Gas Phase by Mass Spectrometry

To investigate the non-covalent interaction between cyclodextrins （CD） and lithium ion, a stoichiometry of α-CD, β-CD, heptakis（2,6-di-O-methyl）-β-CD （DM-β-CD）, or heptakis（2,3,6-tri-O-methyl）-β-CD （TM-β-CD） was mixed with lithium salt, respectively, and then incubated at room temperature for 10 min to reach the equilibrium. In posi- tive mode, the electrospray ionization mass spectrometry （ESI-MS） results demonstrated that lithium ion can conjugate to α-, β-, DM-β- or TM-β-CD and form 1：1 stoichiometric non-covalent complexes. The binding of the complexes was further confirmed by collision- induced dissociation. The dissociation constants Kdl of four complexes （Li＋α-CD, Li＋β- CD, Li＋DM-β-CD, and Li＋TM-β-CD） were determined by mass spectrometric titration. The results showed Kdl were 18.7, 26.7, 33.6, 30.5 μmol/L for the complexes of Li＋ with α-CD, β-CD, DM-β-CD, and TM-β-CD, respectively. Kdl for the Li＋ complexes of/3-CD is smaller than that of DM-β-CD due to its steric effect of the partial substituted -CH3. The Kdl for the Li＋ complexes of DM-β-CD is nearly in agreement with that of TM-β-CD, indicating Li＋ is more likely to locate in the small rim of DM-β-CD＇s hydrophobic cavity. The DFT results showed through electrostatic interaction, one Li＋ can strongly conjugate to four neighboring oxygen atoms. For the （α-CD＋Li）＋ complex, one Li＋ may also situate the small rim of α-CD＇s hydrophobic cavity to form a non-specific host-guest complex.

Effect of inlet configuration on hydrocyclone performance

Inlet configuration is important parameter of hydrocyclones,which has great impact on the classification performance.The effects of inlet configuration on the precise classification were studied by computational fluid dynamics under variouscombinations of inlet diameter and inlet velocity.The results showed that a high sharpness of classification was achieved withspecific inlet diameter and inlet velocity.The separation efficiency of the coarse particles by underflow significantly decreased wheninlet had an oversize diameter owing to a stronger short-circuit flow.It is resulted from the chaotic flow and the stronger pressuregradient around the vortex finder.Meanwhile,a low separation efficiency of the fine particles by overflow was achieved when inletvelocity was high,which indicated a low sharpness caused by the overlarge centrifugal force.

Salting-in/Salting-out Mechanism of Carbon Dioxide in Aqueous Electrolyte Solutions

The solvation of carbon dioxide in sea water plays an important role in the carbon circle and the world climate. The salting-out/salting-in mechanism of CO2 in electrolyte solutions still remains elusive at molecule level. The ability of ion salting-out/salting-in CO2 in electrolyte solution follows Hofmeister Series and the change of water mobility induced by salts can be predicted by the viscosity B-coefficients. In this work, the chemical potential of carbon dioxide and the dynamic properties of water in aqueous NaCl, KF and NaClO4 solutions are calculated and analyzed. According to the viscosity B-coefficients, NaClO4 （0.012） should salt out the carbon dioxide relative to in pure water, but the opposite effect is observed for it. Our simulation results suggest that the salting-in effect of NaClO4 is due to the strongly direct anion-CO2 interaction. The inconsistency between＂ Hofmeister Series and the viscosity B-coefficient suggests that it is not always right to indicate whether a salt belongs to salting-in or salting-out just from these properties of the salt solution in the absence of solute.

Numerical simulation of temperature and velocity fields in plasma spray

Based on the turbulence jet model, with respect to Ar-He mixture plasma gas injecting to ambient atmosphere, the temperature filed and velocity field under typical working conditions were investigated. Given the conditions of I=900 A, FAr= 1.98 m^3/h, FEe=0.85 m^3/h, it is found that both the temperature and the velocity undergo a plateau region near the nozzle exit （0-10 mm） at the very first stage, then decrease abruptly from initial 13 543 K and 778.2 m/s to 4 000 K and 260.0 m/s, and finally decrease slowly again. Meanwhile, the radial temperature and radial velocity change relatively slow. The inner mechanism for such phenomena is due to the complex violent interaction between the high-temperature and high-velocity turbulent plasma jet and the ambient atmosphere. Compared with traditional methods, the initial working conditions can be directly related to the temperature and velocity fields of the plasma jet by deriving basic boundary conditions.

Numerical prediction of vortex flow and thermal separation in a subsonic vortex tube

This work was aimed at gaining understanding of the physical behaviours of the flow and temperature separation process in a vortex tube. To investigate the cold mass fraction’s effect on the temperature separation, the numerical calculation was carried out using an algebraic Reynolds stress model (ASM) and the standard k-ε model. The modelling of turbulence of com-pressible, complex flows used in the simulation is discussed. Emphasis is given to the derivation of the ASM for 2D axisymmet-rical flows, particularly to the model constants in the algebraic Reynolds stress equations. The TEFESS code, based on a staggered Finite Volume approach with the standard k-ε model and first-order numerical schemes, was used to carry out all the computations. The predicted results for strongly swirling turbulent compressible flow in a vortex tube suggested that the use of the ASM leads to better agreement between the numerical results and experimental data, while the k-ε model cannot capture the stabilizing effect of the swirl.

Design of similarity measure for discrete data and application to multi-dimension

Similarity measure design for discrete data group was proposed. Similarity measure design for continuous membership function was also carried out. Proposed similarity measures were designed based on fuzzy number and distance measure, and were proved. To calculate the degree of similarity of discrete data, relative degree between data and total distribution was obtained. Discrete data similarity measure was completed with combination of mentioned relative degrees. Power interconnected system with multi characteristics was considered to apply discrete similarity measure. Naturally, similarity measure was extended to multi-dimensional similarity measure case, and applied to bus clustering problem.

A non-invasive method for gastrointestinal parameter monitoring

AIM: To propose a new, non-invasive method for monitoring 24-h pressure, temperature and pH value in gastrointestinal tract.METHODS: The authors developed a miniature, multifunctional gastrointestinal monitoring system, which comprises a set of indigestible biotelemetry capsules and a data recorder.The capsule, after ingested by patients, could measure pressure, temperature and pH value in the gastrointestinal tract and transmit the data to the data recorder outside the body through a 434 MHz radio frequency data link. After the capsule passed out from the body, the data saved in the recorder were downloaded to a workstation via a special software for further analysis and comparison.RESULTS: Clinical experiments showed that the biotelemetry capsules could be swallowed by volunteers without any difficulties. The data recorder could receive the radio frequency signals transmitted by the biotelemetry in the body. The biotelemetry capsule could pass out from the body without difficulties. No discomfort was reported by any volunteer during the experiment. In vivo pressure and temperature data were acquired.CONCLUSION: A non-invasive method for monitoring 24-h gastrointestinal parameters was proposed and tested by the authors. The feasibility and functionality of this method are verified by laboratory tests and clinical experiments.

Coupling effects of influence factors on probability of corrosion initiation time of reinforced concrete

The coupling model of major influence factors such state affecting the chloride diffusion process in concrete is as environmental relative humidity, load-induced crack and stress discussed. The probability distributions of the critical chloride concentration Cc, the chloride diffusion coefficient D, and the surface chloride concentration Cs were determined based on the collected natural exposure data. And the estimation of probability of corrosion initiation considering the coupling effects of influence factors is presented. It is found that the relative humidity and curing time are the most effective factors affecting the probability of corrosion initiation before and after 10 years of exposure time. At the same exposure time, the influence of load-induced crack and stress state on the probability of corrosion initiation is obvious, in which the effect of crack is the most one

Particle stratification and penetration of a linear vibrating screen by the discrete element method

A simulation of stratification and penetration was performed over a range of structural parameters that included screen width, aperture size, inclination angle, and wire diameter. The discrete element method （DEM） was used for the simulations. The terms stratification and penetration are defined and the change in fine panicle concentration is discussed. Mathematical models relating fine particle ratio to time are established using the least squares method. The effect of structural parameters on fine panicle ratio is analyzed. Stratification and penetration rate are discussed by considering the time derivative of the fine panicle ratio. The conclusions are： an increase in inclination or wire diameter has a positive effect on par- ticle stratifying; The optimal screen width is 40 mm for panicle stratification; The inclination angle has a negative effect on the penetration; The effect of wire diameter and screen width on the penetration rate is negligible.

THE THEORETICAL STUDY OF ADSORPTION OF METAL IONS ON CHITOSAN

The interactions between metal ions such as Zn2+, Pb2+, Mn2+, Hg2+, Cd2+, Ni2+ and chitosan have been investigated using the model cluster model method and density functional method. Full optimization and frequency analysis of all cluster models have been performed employing B3LYP hybrid method at 3-21G basis set level except metal ions which were invoked to use effective core potential (ECP) method. The energy changes, and the main structural parameters have been obtained during the theoretical study of the adsorption of metal ions on the chitosan. The calculations showed that the coordination modes of metal ions with chitosan models were different, the geometries of Mn2+, Zn2+, Cd2+, Hg2+, Pb2+ ions coordinated with two nitrogen atoms and two oxygen atoms were distorted tetrahedral, while the square planar structure of Ni2+ coordinated two nitrogen atoms and two oxygen atoms was observed. The heat of reaction between six metal ions and chitosan models showed the order: Mn2+ >Ni2+ >Zn2+ >Pb2+ >Hg2+ >Cd2+, this suggested that the coordination strength of Mn2+ >Ni2+ >Zn2+ >Pb2+ >Hg2+ >Cd2+.

A Research Note on the Adsorption of CO2 and N2

Experiments were made for the adsorption of CO2 and N2 on typical adsorbents to investigate the effects of porous structure and surface affinity of adsorbents as well as those of adsorption temperature and pressure that might cause the variation of adsorption mechanism. It is shown that polar surface tends to enlarge the adsorption difference between CO2 and N2, and the difference is more sensitive to temperature than the adsorbents with non-polar surface. The adsorbents with non-polar surface are not much sensitive to the effect of water vapor, though the water vapor interferes the separation remarkably. The separation coefficient linearly increases with the micro- pore volume per unit surface area of activated carbons, but no rule is shown on mesoporous silicon materials. The function of adsorption mechanism on the separation is not as much as expected.

Reliability-based service life prediction of existing concrete structures under marine environment

Chloride-induced corrosion of the reinforcement is considered as one of the major mechanisms resulting in the reduction of structural resistance of reinforced concrete structural elements located in marine and other aggressive environments. A study of reinforced concrete structures located at the Fangcheng dock in the Beibu Gulf port, China, was present. The result from field survey indicates that the concrete cover depth and chloride diffusion coefficient fit best normal distribution and lognormal distribution, respectively. The service life of structure is about 55 a, while initiation time is 45 a. Sensitivity analysis indicates that the most influential factor of the structure service life prediction is concrete cover, followed by diffusion coefficient, diffusion decay index, critical chloride concentration, surface chloride concentration, current density and localized pitting corrosion. Finally, the effects of diffusion decay index and critical chloride concentration on structure service life prediction are discussed.

Water Effect on Amine-Modification of Adsorbents for Separation of CO_2/N_2

The adsorption of CO2can be enhanced through loading amines on adsorbents,therefore,the separation of CO2from other gases is promoted.Water plays an important role in this process.Water increases both the adsorption amount of CO2and the separation coefficient with N2for all amines loaded.However,the effect of loading trialkylamines is not remarkable in the absence of water.The effect of loading dialkylamine does not depend on water,but the adsorbent cannot be regenerated at ambient temperature.In comparison,an adsorbent loading trialkylamine can be regenerated at ambient temperature even in the presence of water with fairly good stability.

Similarity measure design and similarity computation for discrete fuzzy data

The similarity computations for fuzzy membership function pairs were carried out.Fuzzy number related knowledge was introduced,and conventional similarity was compared with distance based similarity measure.The usefulness of the proposed similarity measure was verified.The results show that the proposed similarity measure could be applied to ordinary fuzzy membership functions,though it was not easy to design.Through conventional results on the calculation of similarity for fuzzy membership pair,fuzzy membership-crisp pair and crisp-crisp pair were carried out.The proposed distance based similarity measure represented rational performance with the heuristic point of view.Furthermore,troublesome in fuzzy number based similarity measure for abnormal universe of discourse case was discussed.Finally,the similarity measure computation for various membership function pairs was discussed with other conventional results.

Application of silver nitrate colorimetric method to non-steady-state diffusion test

NT build 443, or profile fitting method, is often used to measure the diffusion coefficient of chloride in concrete. However, this method is quite laborious and needs special equipment. Colorimetric method is a quick and simple method to measure the penetration depth of chloride by spraying 0.1 mol/L silver nitrate solution. The objective of this work is to study the possibility of the use of colorimetric method in the calculation of non-steady-state diffusion coefficient. Twelve concrete mixtures with different supplementary cementitious materials and water-to-cement ratios of 0.35, 0.48 and 0.6 were used for study. According to NT build 443, the concrete specimens were immersed in 165 g/L NaC1 （2.8 mol/L） solution for 42 d. Both water-soluble （convert to free chloride） chloride and acid-soluble chloride at different layers of specimens were measured. The results show that the mean value of free chloride concentration at the color change boundary Cd was 0.306 mol/L. The surface free chloride concentration cs was obtained by profile fitting method, which was 40% lower than the chloride concentration of exposure solution after an immersion period of 42 d. Chloride diffusion coefficients obtained by the colorimetric method was not well correlated with those obtained by profile fitting method.

Ultrasonic characterization of modified Cr_2O_3 coatings by reflection coefficient spectroscopy

Pores,microcracks and density of plasma sprayed Cr2O3 coatings before and after high-intensity pulsed ion beam(HIPIB) irradiation were investigated using the ultrasonic reflection coefficient spectroscopy(URCS).The URCS was analyzed based on an acoustic transmission model for the multi-layered structure.The longitudinal velocity in the coatings was calculated from the experimental URCS,and the attenuation coefficient expression was deduced by comparing the experimental and numerical fitting amplitude spectral lines.The longitudinal velocity of as-sprayed Cr2O3 coating is 2 002 m/s,and increases to 2 099 and 2 148 m/s after being irradiated by HIPIB with 1 and 5 shots.Correspondingly,the factor A changes from 0.046 to 0.026 and 0.020 and n from 1.702 to 1.658 and 1.649 in the attenuation coefficient expression of α=Af n.It is observed that the surface morphology of Cr2O3 coatings changes from rough and porous to smooth and uniform with the increase of shot number,which accords with the ultrasonic analyses reasonably.The URCS seems to provide a convenient and nondestructive method to characterize surface modification of the plasma sprayed coatings.

A new algorithm for estimating gillnet selectivity

The estimation of gear selectivity is a critical issue in fishery stock assessment and management.Several methods have been developed for estimating gillnet selectivity,but they all have their limitations,such as inappropriate objective function in data fitting,lack of unique estimates due to the difficulty in finding global minima in minimization,biased estimates due to outliers,and estimations of selectivity being influenced by the predetermined selectivity functions.In this study,we develop a new algorithm that can overcome the above-mentioned problems in estimating the gillnet selectivity.The proposed algorithms include minimizing the sum of squared vertical distances between two adjacent points and minimizing the weighted sum of squared vertical distances between two adjacent points in the presence of outliers.According to the estimated gillnet selectivity curve,the selectivity function can also be determined.This study suggests that the proposed algorithm is not sensitive to outliers in selectivity data and improves on the previous methods in estimating gillnet selectivity and relative population density of fish when a gillnet is used as a sampling tool.We suggest the proposed approach be used in estimating gillnet selectivity.

A step forward parameter for the effects of transcatheter aortic valve implantation： transmural dispersion of repolarization

We read the article ＂Effect of transcatheter aortic valve implantation on QT dispersion in patients with aortic stenosis＂ by Erkan, et al. with great interest. In this study, they investigated the effect of transcatheter aortie valve implantation （TAVI） on QT dispersion （QTd） in patients with symptomatic severe aortic stenosis.

Pervaporation Separation of Butanol-Water Mixtures Using Polydimethylsiloxane/Ceramic Composite Membrane

Pervaporation has attracted considerable interest owing to its potential application in recovering biobutanol from biomass acetone-butanol-ethanol (ABE) fermentation broth. In this study, butanol was recovered from its aqueous solution using a polydimethylsiloxane (PDMS)/ceramic composite pervaporation membrane. The effects of operating temperature, feed concentration, feed flow rate and operating time on the membrane pervaporation performance were investigated. It was found that with the increase of temperature or butanol concentration in the feed, the total flux through the membrane increased while the separation factor decreased slightly. As the feed flow rate increased, the total flux increased gradually while the separation factor changed little. At 40°C and 1% (by mass) butanol in the feed, the total flux and separation factor of the membrane reached 457.4 g·m?2·h?1 and 26.1, respectively. The membrane with high flux is suitable for recovering butanol from ABE fermentation broth.