Background Large-scale clinical research on the relationship between red blood cell distribution width （RDW） and intermediate-term prognosis in elderly patients with coronary artery disease （CAD） is lacking. Thus,...Background Large-scale clinical research on the relationship between red blood cell distribution width （RDW） and intermediate-term prognosis in elderly patients with coronary artery disease （CAD） is lacking. Thus, this study investigated the effects of RDW on the intermediate-term mortality of elderly patients who underwent elective percutaneous coronary intervention （PCI）. Methods Data from 1891 patients 〉 65 years old underwent elective PCI from July 2009 to September 2011 were collected. Based on preoperative median RDW （12.3%）, the patients were divided into two groups. The low RDW group （RDW 〈 12.3%） had 899 cases; the high RDW group （RDW 〉 12.3%） had 992 cases. The all-cause mortality rates of the two groups were compared. Results Patients in the high RDW group were more likely to be female and accompanied with diabetes, had lower hemoglobin level. The mean follow-up period was 527 days. During follow-up, 61 patients died （3.2%）. The postoperative mortality of the high RDW group was significantly higher than that of the low RDW group （4.3% vs. 2.0%, P = 0.004）. After adjusting other factors, multivariate Cox regression analysis revealed that preoperative high RDW was significantly associated with postoperative all-cause mortality （hazard ratio： 2.301, 95% confidence interval： 1.106-4.785, P = 0.026）. Conclusions Increased RDW was an independent predictor of the increased intermediate-term all-cause mortality in elderly CAD patients after elective PCI.展开更多
To the Editor In a recent issue of Journal of Geriatric Cardiology, we read the article by LIU, et al. with interest.~lJ They aimed to investigate whether red cell distribution width （RDW） had a relationship with m...To the Editor In a recent issue of Journal of Geriatric Cardiology, we read the article by LIU, et al. with interest.~lJ They aimed to investigate whether red cell distribution width （RDW） had a relationship with mortality in elderly patients after percuta- neous coronary intervention （PCI）. The authors concluded that, RDW is an independent predictor of the increased in- termediate-term all-cause mortality in elderly patients after PCI. The easy availability of testing for RDW at no addi- tional cost may encourage its broader use in clinical practice We would like to thank the authors for their comprehensive contribution.展开更多
文摘Background Large-scale clinical research on the relationship between red blood cell distribution width （RDW） and intermediate-term prognosis in elderly patients with coronary artery disease （CAD） is lacking. Thus, this study investigated the effects of RDW on the intermediate-term mortality of elderly patients who underwent elective percutaneous coronary intervention （PCI）. Methods Data from 1891 patients 〉 65 years old underwent elective PCI from July 2009 to September 2011 were collected. Based on preoperative median RDW （12.3%）, the patients were divided into two groups. The low RDW group （RDW 〈 12.3%） had 899 cases; the high RDW group （RDW 〉 12.3%） had 992 cases. The all-cause mortality rates of the two groups were compared. Results Patients in the high RDW group were more likely to be female and accompanied with diabetes, had lower hemoglobin level. The mean follow-up period was 527 days. During follow-up, 61 patients died （3.2%）. The postoperative mortality of the high RDW group was significantly higher than that of the low RDW group （4.3% vs. 2.0%, P = 0.004）. After adjusting other factors, multivariate Cox regression analysis revealed that preoperative high RDW was significantly associated with postoperative all-cause mortality （hazard ratio： 2.301, 95% confidence interval： 1.106-4.785, P = 0.026）. Conclusions Increased RDW was an independent predictor of the increased intermediate-term all-cause mortality in elderly CAD patients after elective PCI.
文摘To the Editor In a recent issue of Journal of Geriatric Cardiology, we read the article by LIU, et al. with interest.~lJ They aimed to investigate whether red cell distribution width （RDW） had a relationship with mortality in elderly patients after percuta- neous coronary intervention （PCI）. The authors concluded that, RDW is an independent predictor of the increased in- termediate-term all-cause mortality in elderly patients after PCI. The easy availability of testing for RDW at no addi- tional cost may encourage its broader use in clinical practice We would like to thank the authors for their comprehensive contribution.
