针刺雷火灸及刺络拔罐治疗膝关节骨性关节炎50例

目的:探讨针刺结合雷火灸及痛点刺络拔罐治疗膝关节骨性关节炎的疗效。方法:采用针刺、雷火灸及痛点刺络拔罐治疗膝关节骨性关节炎患者50例,疗程2周。结果:总有效率100%。结论:针刺结合雷火灸及痛点刺络拔罐治疗膝关节骨性关节炎有活血消肿止痛利膝的功效。

Efficacy observation on degenerative gonitis treated with triple needling combined with thunder-fire moxibustion

Objective To evaluate the clinical efficacy of degenerative gonitis treated with triple needling combined with thunder-fire moxibustion for better promotion and clinical application. Methods Ninety-eight patients with degenerative gonitis were randomly divided into a thunder-fire moxibustion group （group A） and an acupuncture group （group B） according to randon number table, with forty-nine cases in each group. In group A, Neixiyan （内膝眼 EX-LE 4）, Dubi （犊鼻 ST 35）, Yanglingquan （阳陵泉 GB 34）, Xuehai （血海 SP 10）, Liangqiu （梁丘 ST 34）, Zusanli （足三里 ST 36）, Yinlingquan （阳陵泉 SP 9） and Xiyangguan （膝阳关 GB 33） were selected to accept triple and needling thunder-fire moxibustion for 20 min after the needles were retained for 40 min. The patients in group B were only treated with acupuncture. Thunder-fire moxibustion was not applied in the group B. The treatment was given once a day for four weeks. Knee function score and knee stiffness score in both groups were recorded before and after treatment, and the therapeutic effect was assessed. Results After four weeks＇ treatment, the total effective rate of group A was 93.9% （46/49）, which was superior to 71.4% （35/49） in group B （P〈0.05）. Improvement in knee stiffness in group A was superior to that in group B （P〈0.01）. Conclusion Triple needling combined with thunder-fire moxibustion had clinical efficacy on degenerative gonitis, which is a better treatment option with the total efficacy significantly superior to that of acupuncture only.

Mild moxibustion plus loratadine tablets for children with allergic rhinitis:a randomized controlled trial

Objective To explore the efficacy of mild moxibustion plus loratadine tablets for children with allergic rhinitis(AR).Methods A total of 80 children were randomized into a control group and an observation group,with 40 cases in each group.The control group was treated with loratadine tablets,and the observation group was treated with mild moxibustion plus loratadine tablets.Before and after treatment,the total nasal symptom score(TNSS)was evaluated,and the serum eosinophils(EOS)count,and the interleukin(IL)-27 and macrophage migration inhibitory factor(MIF)levels were measured.Clinical efficacy was evaluated after treatment.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the TNSS in both groups decreased(P<0.05),and the TNSS in the observation group was lower than that in the control group(P<0.05);the serum EOS count in both groups decreased(P<0.05),and the serum EOS count in the observation group was lower than that in the control group(P<0.05).The serum IL-27 level in the control group had no statistical difference compared with the same group before treatment(P>0.05),and the serum MIF level decreased after treatment(P<0.05).The serum IL-27 level in the observation group increased after treatment(P<0.05),and the serum MIF level decreased after treatment(P<0.05),and were both statistically different from those in the control group(P<0.05).Conclusion Mild moxibustion plus loratadine tablets is effective in treating children with AR.It can significantly improve the nasal symptoms and reduce the serum EOS count,which may be related to the regulation of the serum IL-27 and MIF levels.

Effect of acupuncture plus thunder-fire moxibustion on MMP-3, TIMP-1 and TGF-β1 in rats with knee osteoarthritis

Objective： To observe the effect of acupuncture plus thunder-fire moxibustion on the expressions of matrix metalloproteinase-3 （MMP-3）, tissue inhibitor of metalloproteinase-1 （TIMP-1） and transforming growth factor-β1 （TGF-β1） in cartilage of knee osteoarthritis （KOA） rats, and to explore the mechanism of acupuncture plus thunder-fire moxibustion in the treatment of KOA. Methods： Thirty Sprague-Dawley （SD） rats were randomly divided into a blank control group, a model group and an acupuncture-moxibustion group by random digits table, 10 rats in each group. Rats in the model group and the acupuncture-moxibustion group were injected with papain in the right posterior knee joint to prepare the models. The levels of MMP-3 and TIMP-1 in rat synovium of each group were measured by enzyme-linked immunosorbent assay （ELBA） after 2 weeks of treatment. The level of TGF-β1 was determined by Motic B5 Micro-camera system. Results： The levels of MMP-3 and TIMP-1 in the cartilage of the model group were significantly higher than those in the blank control group （all P〈0.01）; the levels of MMP-3 and TIMP-1 in the acupuncture-moxibustion group were lower than those in the model group, and the between-group differences were statistically significant （all P〈0.05）. The levels of MMP-3 and TIMP-1 in the acupuncture-moxibustion group were higher than those in the blank control group, and the differences were statistically significant （all P〈0.05）. The level of TGF-β1 in cartilage tissues of the model group was significantly lower than that in the blank control group （P〈0.01）; the level of TGF-β1 in the acupuncture-moxibustion group was higher than that in the model group （P〈0.05）, but it was lower than that in the blank control group, and the between-group difference was statistically significant （P〈0.05）. Conclusion： Acupuncture plus thunder-fire moxibustion can effectively recover the abnormal expressions of MMP-3 and TIMP-1 in KOA model rats and somewhat up-regulate TGF-β1, which may be one of its mechanisms of acupuncture plus thunder-fire for KOA.