This paper will discuss the computerised developm en t control and approval system being developed for the Planning and Development C ontrol Department, City Hall of Kuala Lumpur, with stress on the GIS architectur e ...This paper will discuss the computerised developm en t control and approval system being developed for the Planning and Development C ontrol Department, City Hall of Kuala Lumpur, with stress on the GIS architectur e developed within the system. The prospects and challenges towards implementati on of the system are also discussed.展开更多
In hearing physiological experiments and clinic tests,we need not only a signal processing system,but also a synchronous sound stimulator’ Most of stimulators we are now using are function generators which are indepe...In hearing physiological experiments and clinic tests,we need not only a signal processing system,but also a synchronous sound stimulator’ Most of stimulators we are now using are function generators which are independent to processing units,and can be controlled only by hand. Although some of them have ports through which they can be controlled by computer,but as they are designed for industrial aims,not for hearing research,most of them can’t generate the special waveforms we need. We use the TDT signal processing system and develop a software package have both usage. On the interface of the program we can control the sampling parameters and generate stimulating waveforms’展开更多
Serious desertification caused by human activity and climate change,in addition to water loss and soil erosion related to arsenic sandstone in the Mu Us Sandy Land,lead to severe scarcity of soil and water resources,w...Serious desertification caused by human activity and climate change,in addition to water loss and soil erosion related to arsenic sandstone in the Mu Us Sandy Land,lead to severe scarcity of soil and water resources,which causes worse local agricultural conditions accordingly.Many physical properties of arsenic sandstone is complementary with that of sand,arsenic sandstone is therefore supposed to be blended to enhance water productivity and arability of sandy land.Container experiments are carried out to study the enhancement of water holding capacity of the mixture,the blending ratio of arsenic sandstone and sand,and the proper size of the arsenic sandstone particles,respectively.The results of the experiments show that particle size of 4 cm with a ratio of 1∶2 between arsenic sandstone and sand are the proper parameters on blending.Both water content and fertility increase after blending.Water use efficiency in the mixture is 2.7 times higher than that in sand by the water release curves from experiments.Therefore,a new sand control and development model,including arsenic sandstone blending with sand,efficient water irrigation management and reasonable farming system,is put forward to control and develop sandy land so that water-saving agriculture could be developed.Demonstration of potato planting about 153.1 ha in area in the Mu Us Sandy Land in China indicates that water consumption is 3018 m3/ha in the whole growth period.It means that about 61%of irrigation water can be saved compared with water use in coarse sand without treatment.Recycle economic mode and positive feedback of sand resource-crop planting-soil resource are constructed,which changes sand into arable soil and make it possible to develop water-saving agriculture on it.The proposed model will be helpful for soil-water resources utilization and management in the Mu Us Sandy Land.展开更多
How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated i...How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal genetic diseases that exhibit craniofacial bone defects. The GNAS gene encodes Gαs that transduces GPCR signaling. GNAS activation or loss-of-function mutations in humans cause fibrous dysplasia(FD) or progressive osseous heteroplasia(POH) that shows craniofacial hyperostosis or craniosynostosis, respectively. We find here that, while Hh ligand-dependent Hh signaling is essential for endochondral ossification, it is dispensable for intramembranous ossification, where Gαsregulates Hh signaling in a ligand-independent manner. We further show that Gαscontrols intramembranous ossification by regulating both Hh and Wnt/β-catenin signaling. In addition, Gαsactivation in the developing cranial bone leads to reduced ossification but increased cartilage presence due to reduced cartilage dissolution, not cell fate switch. Small molecule inhibitors of Hh and Wnt signaling can effectively ameliorate cranial bone phenotypes in mice caused by loss or gain of Gnas function mutations, respectively. Our work shows that studies of genetic diseases provide invaluable insights in both pathological bone defects and normal bone development, understanding both leads to better diagnosis and therapeutic treatment of bone diseases.展开更多
As a hot spot of next generation network, research over resource control has been carried out for years both in China and abroad. With a gradual progress in standardization, this field presents new development trends ...As a hot spot of next generation network, research over resource control has been carried out for years both in China and abroad. With a gradual progress in standardization, this field presents new development trends and features. Based on latest progresses in standardization promoted by ITU-T, TISPAN and 3GPP, new technologies concerned with resource control are introduced. Considering the problems faced in standardization deployment, relevant resource control functions are also analyzed in this article.展开更多
Light is one of the key environmental signals regulating plant growth and development.Therefore,understanding the mechanisms by which light controls plant development has long been of great interest to plant biologist...Light is one of the key environmental signals regulating plant growth and development.Therefore,understanding the mechanisms by which light controls plant development has long been of great interest to plant biologists.Traditional genetic and molecular approaches have successfully identified key regulatory factors in light signaling,but recent genomic studies have revealed massive reprogramming of plant transcriptomes by light,identified binding sites across the entire genome of several pivotal transcription factors in light signaling,and discovered the involvement of epigenetic regulation in light-regulated gene expression.This review summarizes the key genomic work conducted in the last decade which provides new insights into light control of plant development.展开更多
Root hairs are tubular outgrowths specifically differentiated from epidermal cells in a differentiation zone. The formation of root hairs greatly increases the surface area of a root and maximizes its ability to absor...Root hairs are tubular outgrowths specifically differentiated from epidermal cells in a differentiation zone. The formation of root hairs greatly increases the surface area of a root and maximizes its ability to absorb water and inorganic nutrients essential for plant growth and development. Root hair development is strictly regulated by intracellular and intercellular signal communications. Cell surface-localized receptor-like protein kinases （P, LKs） have been shown to be important components in these cellular processes, tn this review, the functions of a number of key P, LKs in regulating Arabidopsis root hair development are discussed, especially those involved in root epidermal cell fate determination and root hair tip growth.展开更多
This study aimed at investigating the causes of floods in Numan Town with particular reference to the 2012 floods. Three residential areas： Gangare, Gwadda Mallam and Green Village were selected for the study. Hydrol...This study aimed at investigating the causes of floods in Numan Town with particular reference to the 2012 floods. Three residential areas： Gangare, Gwadda Mallam and Green Village were selected for the study. Hydrological, SRTM （shuttle radar topography mission） digital elevation model, secondary and primary data were utilized. A total of 180 questionnaires were administered to the residents in equal proportion using systematic random sampling. ArcGIS 10.0 and Excel were used for the analysis. The study revealed that the major causes of flood in the area include discharge of water from the Lagdo dam in Cameroon and Kiri dam in Adamawa State. Others include heavy rainfall, topography, and lack of adherence to development control provisions which resulted in construction of residential areas on flood plains. Many of the residents do not have legal title to their plots and this constitutes a very serious constraint to provision of drainages and solid waste disposal services. To ameliorate the devastating effects of floods, the study recommends relocation of residents of flood prone areas, provision of solid waste management services, and construction of more drainages. In addition, the town planning authorities and community leaders should collaborate to ensure that houses are built in flood plains.展开更多
Kenya has amassed a wealth of paper based land information records collected over the duration of more than a century. The National Land Commission (NLC) having the mandate to develop a National Land Information Manag...Kenya has amassed a wealth of paper based land information records collected over the duration of more than a century. The National Land Commission (NLC) having the mandate to develop a National Land Information Management System (NLIMS) for Kenya partnered with the Dedan Kimathi University of Technology on a project to develop a pilot LIMS for Nyeri County. A pilot Land Administration System (LAS) has been developed in this work and utilizes an Africanized Land Administration Domain Model (A-LADM) fitted to the Kenyan context. Various processes involved in land administration that required to be automated were identified. Informed by the numbers of applications made for the change of User service, it was picked as the first workflow to be automated. The key outputs of this work were the A-LADM and pilot LAS. The pilot solution uses a webcentric solution, with the data stored and managed centrally from a PostGIS database backend, using the Python Django framework to implement the server side and client side frontend. This solution demonstrates the importance of automating processes and supporting standards based software development. Stakeholder participation is key when implementing systems and 2 workshops are held to capture requirements and validate the developed solution.展开更多
Traditional Chinese Medicine has been very popular in Taiwan in the past.TCM was incorporated in the National Insurance since 1995.Starting 2012,all new TCM physicians had to be graduated from TCM Department in Medica...Traditional Chinese Medicine has been very popular in Taiwan in the past.TCM was incorporated in the National Insurance since 1995.Starting 2012,all new TCM physicians had to be graduated from TCM Department in Medical University.Currently,there are 6,442 TCM physicians practiced in 3,372 clinics and 95 hospitals.TCM only accounts for less than 4%of total National Health展开更多
Saffron,the dried stigma of Crocus sativus L.,findsnumerous applications in TCM.Here,a novel HPLC protocol was established and applied for the analysis of saffron samples,not only from different places of origin but a...Saffron,the dried stigma of Crocus sativus L.,findsnumerous applications in TCM.Here,a novel HPLC protocol was established and applied for the analysis of saffron samples,not only from different places of origin but also from several harvest seasons.One of the main active constituents of saffron,crocin,is also contained in展开更多
文摘This paper will discuss the computerised developm en t control and approval system being developed for the Planning and Development C ontrol Department, City Hall of Kuala Lumpur, with stress on the GIS architectur e developed within the system. The prospects and challenges towards implementati on of the system are also discussed.
文摘In hearing physiological experiments and clinic tests,we need not only a signal processing system,but also a synchronous sound stimulator’ Most of stimulators we are now using are function generators which are independent to processing units,and can be controlled only by hand. Although some of them have ports through which they can be controlled by computer,but as they are designed for industrial aims,not for hearing research,most of them can’t generate the special waveforms we need. We use the TDT signal processing system and develop a software package have both usage. On the interface of the program we can control the sampling parameters and generate stimulating waveforms’
基金Under the auspices of National Natural Science Foundation of China(No.51079120)Education Department Research Program of Shaanxi Province(No.12JK0481)Water Conservancy Science and Technology Plan of Shaanxi Province(No.2012-07)
文摘Serious desertification caused by human activity and climate change,in addition to water loss and soil erosion related to arsenic sandstone in the Mu Us Sandy Land,lead to severe scarcity of soil and water resources,which causes worse local agricultural conditions accordingly.Many physical properties of arsenic sandstone is complementary with that of sand,arsenic sandstone is therefore supposed to be blended to enhance water productivity and arability of sandy land.Container experiments are carried out to study the enhancement of water holding capacity of the mixture,the blending ratio of arsenic sandstone and sand,and the proper size of the arsenic sandstone particles,respectively.The results of the experiments show that particle size of 4 cm with a ratio of 1∶2 between arsenic sandstone and sand are the proper parameters on blending.Both water content and fertility increase after blending.Water use efficiency in the mixture is 2.7 times higher than that in sand by the water release curves from experiments.Therefore,a new sand control and development model,including arsenic sandstone blending with sand,efficient water irrigation management and reasonable farming system,is put forward to control and develop sandy land so that water-saving agriculture could be developed.Demonstration of potato planting about 153.1 ha in area in the Mu Us Sandy Land in China indicates that water consumption is 3018 m3/ha in the whole growth period.It means that about 61%of irrigation water can be saved compared with water use in coarse sand without treatment.Recycle economic mode and positive feedback of sand resource-crop planting-soil resource are constructed,which changes sand into arable soil and make it possible to develop water-saving agriculture on it.The proposed model will be helpful for soil-water resources utilization and management in the Mu Us Sandy Land.
基金supported by the NIH grants R01DE025866 from NIDCRR01AR070877 from NIAMSsupported by the 111 Project, MOE (B14038), China
文摘How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal genetic diseases that exhibit craniofacial bone defects. The GNAS gene encodes Gαs that transduces GPCR signaling. GNAS activation or loss-of-function mutations in humans cause fibrous dysplasia(FD) or progressive osseous heteroplasia(POH) that shows craniofacial hyperostosis or craniosynostosis, respectively. We find here that, while Hh ligand-dependent Hh signaling is essential for endochondral ossification, it is dispensable for intramembranous ossification, where Gαsregulates Hh signaling in a ligand-independent manner. We further show that Gαscontrols intramembranous ossification by regulating both Hh and Wnt/β-catenin signaling. In addition, Gαsactivation in the developing cranial bone leads to reduced ossification but increased cartilage presence due to reduced cartilage dissolution, not cell fate switch. Small molecule inhibitors of Hh and Wnt signaling can effectively ameliorate cranial bone phenotypes in mice caused by loss or gain of Gnas function mutations, respectively. Our work shows that studies of genetic diseases provide invaluable insights in both pathological bone defects and normal bone development, understanding both leads to better diagnosis and therapeutic treatment of bone diseases.
文摘As a hot spot of next generation network, research over resource control has been carried out for years both in China and abroad. With a gradual progress in standardization, this field presents new development trends and features. Based on latest progresses in standardization promoted by ITU-T, TISPAN and 3GPP, new technologies concerned with resource control are introduced. Considering the problems faced in standardization deployment, relevant resource control functions are also analyzed in this article.
基金the National Basic Research Program of China(973 Program)(Grant No.2012CB910900)National Institutes of Health of the USA(GM47850)+1 种基金the National Science Foundation(NSF)Plant Genome Program of the USA(DBI0922604)the Ministry of Agriculture of China(No.2010ZX08010-003).
文摘Light is one of the key environmental signals regulating plant growth and development.Therefore,understanding the mechanisms by which light controls plant development has long been of great interest to plant biologists.Traditional genetic and molecular approaches have successfully identified key regulatory factors in light signaling,but recent genomic studies have revealed massive reprogramming of plant transcriptomes by light,identified binding sites across the entire genome of several pivotal transcription factors in light signaling,and discovered the involvement of epigenetic regulation in light-regulated gene expression.This review summarizes the key genomic work conducted in the last decade which provides new insights into light control of plant development.
基金supported by grants from the National Natural Science Foundation of China(31700245 to Zhuoyun Wei,31720103902,31470380,and 31530005 to Jia Li)the China Postdoctoral Science Foundation(2018T111116 and 2016M602889 to Zhuoyun Wei)
文摘Root hairs are tubular outgrowths specifically differentiated from epidermal cells in a differentiation zone. The formation of root hairs greatly increases the surface area of a root and maximizes its ability to absorb water and inorganic nutrients essential for plant growth and development. Root hair development is strictly regulated by intracellular and intercellular signal communications. Cell surface-localized receptor-like protein kinases （P, LKs） have been shown to be important components in these cellular processes, tn this review, the functions of a number of key P, LKs in regulating Arabidopsis root hair development are discussed, especially those involved in root epidermal cell fate determination and root hair tip growth.
文摘This study aimed at investigating the causes of floods in Numan Town with particular reference to the 2012 floods. Three residential areas： Gangare, Gwadda Mallam and Green Village were selected for the study. Hydrological, SRTM （shuttle radar topography mission） digital elevation model, secondary and primary data were utilized. A total of 180 questionnaires were administered to the residents in equal proportion using systematic random sampling. ArcGIS 10.0 and Excel were used for the analysis. The study revealed that the major causes of flood in the area include discharge of water from the Lagdo dam in Cameroon and Kiri dam in Adamawa State. Others include heavy rainfall, topography, and lack of adherence to development control provisions which resulted in construction of residential areas on flood plains. Many of the residents do not have legal title to their plots and this constitutes a very serious constraint to provision of drainages and solid waste disposal services. To ameliorate the devastating effects of floods, the study recommends relocation of residents of flood prone areas, provision of solid waste management services, and construction of more drainages. In addition, the town planning authorities and community leaders should collaborate to ensure that houses are built in flood plains.
文摘Kenya has amassed a wealth of paper based land information records collected over the duration of more than a century. The National Land Commission (NLC) having the mandate to develop a National Land Information Management System (NLIMS) for Kenya partnered with the Dedan Kimathi University of Technology on a project to develop a pilot LIMS for Nyeri County. A pilot Land Administration System (LAS) has been developed in this work and utilizes an Africanized Land Administration Domain Model (A-LADM) fitted to the Kenyan context. Various processes involved in land administration that required to be automated were identified. Informed by the numbers of applications made for the change of User service, it was picked as the first workflow to be automated. The key outputs of this work were the A-LADM and pilot LAS. The pilot solution uses a webcentric solution, with the data stored and managed centrally from a PostGIS database backend, using the Python Django framework to implement the server side and client side frontend. This solution demonstrates the importance of automating processes and supporting standards based software development. Stakeholder participation is key when implementing systems and 2 workshops are held to capture requirements and validate the developed solution.
文摘Traditional Chinese Medicine has been very popular in Taiwan in the past.TCM was incorporated in the National Insurance since 1995.Starting 2012,all new TCM physicians had to be graduated from TCM Department in Medical University.Currently,there are 6,442 TCM physicians practiced in 3,372 clinics and 95 hospitals.TCM only accounts for less than 4%of total National Health
文摘Saffron,the dried stigma of Crocus sativus L.,findsnumerous applications in TCM.Here,a novel HPLC protocol was established and applied for the analysis of saffron samples,not only from different places of origin but also from several harvest seasons.One of the main active constituents of saffron,crocin,is also contained in
