目的探讨CT引导下经皮穿刺^124I粒子及5-氟尿嘧啶（5-Fu）缓释剂植入治疗中晚期胰腺癌的临床应用价值。方法13例经证实的中晚期胰腺癌，采用放射性粒子治疗计划系统（treatment plan system，TPS）计算布源，在CT引导下将^124I粒子缓释...目的探讨CT引导下经皮穿刺^124I粒子及5-氟尿嘧啶（5-Fu）缓释剂植入治疗中晚期胰腺癌的临床应用价值。方法13例经证实的中晚期胰腺癌，采用放射性粒子治疗计划系统（treatment plan system，TPS）计算布源，在CT引导下将^124I粒子缓释剂植入瘤灶内，并在^124I粒子间间隔植入5-Fu缓释剂。术后2个月，分别对患者进行CT检查，根据肿瘤大小变化和临床症状缓解程度对疗效进行分级。结果7例患者疼痛完全缓解，2例部分缓解，4例无效，平均术后3d-7d疼痛缓解。6个月后CT复查，完全缓解（CR）1例；部分缓解（PR）6例；无变化（NC）4例；进展（PD）2例。总有效率（CR＋PR）53．8％。术后未见胰瘘、胰腺炎、肠出血、腹腔内脓肿等严重并发症。结论CT引导下经皮穿刺植入^124I粒子及5-Fu缓释剂治疗中晚期胰腺癌创伤小，并发症少，姑息止痛效果好，是治疗中晚期胰腺癌安全，可靠，有效的方法之一。展开更多
We have investigated the structure evolution of the ^124-134Xe isotopic chain in the framework of the proton-neutron interacting model IBM2. The positive parity spectra of the ground state, quasi-β and quasi-γ bands...We have investigated the structure evolution of the ^124-134Xe isotopic chain in the framework of the proton-neutron interacting model IBM2. The positive parity spectra of the ground state, quasi-β and quasi-γ bands are reproduced well. The staggering in ^124-130Xe are almost completely removed and the ？ band agree well with the experiment data, even for the high-spin quasi-3 states. The key quantities of the collective structure evolution, including level energies, the B（E2） transition branching ratios, and the M1 excitations to 11^＋ mixer-symmetry states are analyzed by comparing with the experimental data. The parameters for representation of the Oπν（6） and SUπν^＊（3） features in isotopes are examined. Both experimental data and theoretical results show that the shape phase transition of ^124-134Xe isotopic chain is from the SUπν^＊ （3） （triaxial rotation） to the Uπν（5） （vibration motion） with a considerable constituent of the Oπν（6） symmetry （γ-unstable rotation）, where the shape phase transition rapidly takes place between the neutron number N = 76 and N = 78.展开更多
Based on the neutron and proton degrees of freedom, low-lying energy levels, E2, M1, and E0 transition strengths of nucleus ^(124)Te have been calculated by the neutron-proton interacting boson model. The calculated r...Based on the neutron and proton degrees of freedom, low-lying energy levels, E2, M1, and E0 transition strengths of nucleus ^(124)Te have been calculated by the neutron-proton interacting boson model. The calculated results are reasonably consistent with the experimental data. By comparing the key observables of the states at the critical point of U_(πv)(5)-O_(πv)(6) transition with the experimental data and calculated results, we show that the ^(124)Te is a possible nucleus at the critical point of the second-order phase transition from vibration to unstable rotation, and such a critical point exhibits slight triaxial rotation. The 0_2^+ state of ^(124)Te can be interpreted as the lowest state of the first-excited family of the intrinsic levels in the critical point symmetry.展开更多
文摘目的探讨CT引导下经皮穿刺^124I粒子及5-氟尿嘧啶（5-Fu）缓释剂植入治疗中晚期胰腺癌的临床应用价值。方法13例经证实的中晚期胰腺癌，采用放射性粒子治疗计划系统（treatment plan system，TPS）计算布源，在CT引导下将^124I粒子缓释剂植入瘤灶内，并在^124I粒子间间隔植入5-Fu缓释剂。术后2个月，分别对患者进行CT检查，根据肿瘤大小变化和临床症状缓解程度对疗效进行分级。结果7例患者疼痛完全缓解，2例部分缓解，4例无效，平均术后3d-7d疼痛缓解。6个月后CT复查，完全缓解（CR）1例；部分缓解（PR）6例；无变化（NC）4例；进展（PD）2例。总有效率（CR＋PR）53．8％。术后未见胰瘘、胰腺炎、肠出血、腹腔内脓肿等严重并发症。结论CT引导下经皮穿刺植入^124I粒子及5-Fu缓释剂治疗中晚期胰腺癌创伤小，并发症少，姑息止痛效果好，是治疗中晚期胰腺癌安全，可靠，有效的方法之一。
基金Supported by the National Natural Science Foundation of China under Grant No.11075052the Natural Science Foundation of Zhejiang Province under Grant No.KY6100135
文摘We have investigated the structure evolution of the ^124-134Xe isotopic chain in the framework of the proton-neutron interacting model IBM2. The positive parity spectra of the ground state, quasi-β and quasi-γ bands are reproduced well. The staggering in ^124-130Xe are almost completely removed and the ？ band agree well with the experiment data, even for the high-spin quasi-3 states. The key quantities of the collective structure evolution, including level energies, the B（E2） transition branching ratios, and the M1 excitations to 11^＋ mixer-symmetry states are analyzed by comparing with the experimental data. The parameters for representation of the Oπν（6） and SUπν^＊（3） features in isotopes are examined. Both experimental data and theoretical results show that the shape phase transition of ^124-134Xe isotopic chain is from the SUπν^＊ （3） （triaxial rotation） to the Uπν（5） （vibration motion） with a considerable constituent of the Oπν（6） symmetry （γ-unstable rotation）, where the shape phase transition rapidly takes place between the neutron number N = 76 and N = 78.
基金Supported by the National Natural Science Foundation of China(11475062,11147148,11747312)
文摘Based on the neutron and proton degrees of freedom, low-lying energy levels, E2, M1, and E0 transition strengths of nucleus ^(124)Te have been calculated by the neutron-proton interacting boson model. The calculated results are reasonably consistent with the experimental data. By comparing the key observables of the states at the critical point of U_(πv)(5)-O_(πv)(6) transition with the experimental data and calculated results, we show that the ^(124)Te is a possible nucleus at the critical point of the second-order phase transition from vibration to unstable rotation, and such a critical point exhibits slight triaxial rotation. The 0_2^+ state of ^(124)Te can be interpreted as the lowest state of the first-excited family of the intrinsic levels in the critical point symmetry.
