期刊文献+
共找到28,026篇文章
< 1 2 250 >
每页显示 20 50 100
Modeling Blood Flow in Veins of Uniform Properties (Giraffe Jugular Vein)
1
作者 Rogers Omboga Amenya Johanna Kibet Sigey +1 位作者 Geoffrey Moriaso Ole Maloiy David Mwangi Theuri 《Open Journal of Biophysics》 2024年第2期132-153,共22页
This paper models the giraffe’s jugular veins as a uniform collapsible tube from a rigid skull. The equations governing one-dimensional steady flow through such a tube for various conditions have been developed. The ... This paper models the giraffe’s jugular veins as a uniform collapsible tube from a rigid skull. The equations governing one-dimensional steady flow through such a tube for various conditions have been developed. The effects of inertial and inclination angles that have not been discussed previously have been included. It has been shown that different flows for a uniform tube (vein) are possible. However, this flow matches that of a jugular vein which is supercritical, and the steady solution has been given by the balance between the driving forces of gravity and the viscous resistance to the flow at the right atrium of the heart must be sub-critical for a fixed right-atrium pressure which means that an elastic jump is required to return the flow to sub-critical from the supercritical flow upstream this type of relationship gives rise to flow limitation at the same time given any right atrium fixed pressure there exists a maximum flow rate which when exceeded the boundary conditions of the flow do not hold boundary conditions at the right atrium are not satisfied hence making the steady flow impossible this mechanism of flow limitation is slightly different from the other one in that causes airways through forced expiration from the observation made it is clearly shown that there is an intravascular pressure difference with a change in height. 展开更多
关键词 Blood Flow Jugular vein Cross-Sectional Area SUPERCRITICAL SUBCRITICAL JUMP
下载PDF
Sclerotherapy as the Only Treatment for Varicose Veins
2
作者 Moaath Al-Smady Qutaiba AbuQuba +4 位作者 Ahmad Al-Saraheen Basil Al-Azaideh Malik Allahham Zeenah Alsmady Amjad Bani Hani 《World Journal of Cardiovascular Surgery》 2024年第10期166-180,共15页
Background: Chronic venous insufficiency (CVI) is a widespread and underdiagnosed condition that affects more than 20% of the general population. The most prevalent manifestation of CVI is varicose veins (VVs), which ... Background: Chronic venous insufficiency (CVI) is a widespread and underdiagnosed condition that affects more than 20% of the general population. The most prevalent manifestation of CVI is varicose veins (VVs), which affect up to 25% of women and 15% of males. Sclerotherapy is a minimally invasive procedure used primarily in treating telangiectasias, reticular veins, and small varicose veins. Objectives: This study aims to evaluate the efficacy and safety of various sclerotherapy techniques in treating varicose veins-related complications. Methods: We conducted a cross-sectional observational interventional study at Jordan University Hospital (JUH) from September 2022 to January 2023. The study involved patients with lower limb varicose veins, assessing their clinical response and monitoring potential treatment complications. Statistical analyses were performed using SPSS software version 21.0. Results: Of 567 patients with diagnosed VVs, 544 were female (95.94%), and 23 were male (4.06%). The primary complaints were pain and cosmetic concerns. Treatments included Foam Aethoxysklerol® 3% (polidocanol) and Micro-foam Aethoxysklerol® 1%. Improvement in symptoms was reported by 538 patients (94.89%). The most common adverse event was hyperpigmentation, reported in 120 patients (21.16%), followed by post-procedural pain in 104 patients (18.34%). Notably, one patient (0.18%) experienced deep vein thrombosis (DVT), one (0.18%) reported telangiectatic matting, and there were two cases (0.36%) of visual disturbances and one allergic reaction. Conclusion: Sclerotherapy is effective and safe for treating VVs with minimal adverse events. It is a viable standalone treatment, reducing complications linked to other methods like radiofrequency ablation and surgery. 展开更多
关键词 Chronic Venous Insufficiency Foam Sclerotherapy Varicose veins Adverse Events
下载PDF
Comparative Quantitative Analysis of Retinal Superficial Capillary Plexus in Patients with Retinal Vein Occlusion and Unaffected Fellow Eyes
3
作者 Sinan Aptikadir Nelly Sivkova 《Open Journal of Ophthalmology》 2024年第3期218-228,共11页
Purpose: To evaluate optical coherence tomography angiography (OCT-A) data obtained from the superficial retinal capillary plexus of patients with retinal vein occlusion and comparative analysis with data registered f... Purpose: To evaluate optical coherence tomography angiography (OCT-A) data obtained from the superficial retinal capillary plexus of patients with retinal vein occlusion and comparative analysis with data registered from unaffected fellow eyes. Methods: The examined patients were classified into 2 groups: group 1—eyes with established retinal vein occlusion (n = 29) and group 2—unaffected fellow eyes of patients with retinal vein occlusion (n = 24). The scanning protocol “Angiography 3 × 3 mm” of Zeiss Cirrus HD-OCT 6000, AngioPlex Metrix was used to evaluate the retinal superficial capillary plexus. The analyzed parameters were vascular density and perfusion density, as well as the area, perimeter, and circularity of the foveolar avascular zone (FAZ). Results: The comparative analysis of FAZ parameters at the superficial capillary plexus (SCP) between group 1 (eyes with retinal vein occlusion) and group 2 (unaffected fellow eyes) showed significant results for the three parameters, respectively area (p = 0.003), perimeter (p ≤ 0.001), and circularity (p = 0.011) of FAZ. The comparative analysis of the vascular network at SCP in patients with diagnosed retinal vein occlusion and unaffected fellow eyes showed significant results for vascular density (VD) in the central (p = 0.038) and inner (p ≤ 0.001) zones as well as total VD (p ≤ 0.001) were statistically significant. Moreover, the results obtained in the study of vascular perfusion (VP) indicated significant results in the inner zone (p ≤ 0.001) and total VP (p = 0.001). Vascular perfusion in the central zone (p = 0.116) was the only parameter not to meet significant results. Conclusion: The current study observed a significant enlargement of the FAZ and loss of its circularity, along with a reduction in vascular network parameters at the superficial retinal capillary plexus level. 展开更多
关键词 Retinal vein Occlusion Optical Coherence Tomography Angiography Superficial Retinal Capillary Plexus
下载PDF
Malnutrition Assessed Using the Geriatric Nutritional Risk Index Is Associated with Preoperative Incidence of Deep Vein Thrombosis in Japanese Patients Undergoing Total Knee Arthroplasty
4
作者 Taizo Kaneko Kentaro Hayakawa Tsuyoshi Miyazaki 《Open Journal of Orthopedics》 2024年第8期355-365,共11页
Purpose: Few studies have evaluated the association between malnutrition and the risk of preoperative deep vein thrombosis (DVT) in patients undergoing primary total joint arthroplasty. This study aimed to investigate... Purpose: Few studies have evaluated the association between malnutrition and the risk of preoperative deep vein thrombosis (DVT) in patients undergoing primary total joint arthroplasty. This study aimed to investigate the prevalence of preoperative DVT in Japanese patients undergoing total knee arthroplasty (TKA) and the importance of malnutrition in the risk of preoperative DVT. Methods: We retrospectively analyzed 394 patients admitted for primary TKA at our institution between January 2019 and December 2023. All patients scheduled for TKA at our institution had serum D-dimer levels measured preoperatively. Lower-limb ultrasonography was examined to confirm the presence of DVT in patients with D-dimer levels ≥ 1.0 µg/mL or who were considered to be at high risk of DVT by the treating physician. Based on the results of lower-limb ultrasonography, all patients were divided into the non-DVT and DVT groups. The incidence of and risk factors for preoperative DVT were investigated, as well as the correlation of DVT with the patient’s nutritional parameters. We used two representative tools for nutritional assessment: the Geriatric Nutritional Risk Index (GNRI) and Controlling Nutritional Status Score. Results: The mean age was 77.8 ± 6.9 years. Preoperative DVT was diagnosed in 57 of the 394 (14.5%) patients. Multivariate logistic regression analysis showed that advanced age and malnutrition status, assessed using the GNRI, were independent risk factors for preoperative DVT. Conclusion: A high incidence of preoperative DVT was observed in patients who underwent TKA. Malnutrition status, as assessed using the GNRI, increased the risk of preoperative DVT. Our findings suggest that clinicians should consider these factors when tailoring preventive strategies to mitigate DVT risk in patients undergoing TKA. 展开更多
关键词 MALNUTRITION Geriatric Nutritional Risk Index Controlling Nutritional Status Score PREOPERATIVE Deep vein Thrombosis Total Knee Arthroplasty
下载PDF
A Comparative Analysis on Surgical Outcomes and Complications of Endoscopic and Open Vein Harvesting Techniques
5
作者 Mohammed Fawzy Eltaweel Ismail N. El-Sokkary +7 位作者 Ahmed Alherazi Mohamed Wael Badawi Mohammed G. Abdellatif Bahaa A. Elkhonezy Ibrahim K. Gamil Haytham Mohamed Abd El Moaty Sarra Sadmi Mahmoud Khalil 《Open Journal of Thoracic Surgery》 2024年第2期29-39,共11页
Objective: The great saphenous vein (GSV) is commonly used as a conduit for grafting during CABG surgery, and open GSV harvesting (OVH), commonly used with long incision to expose the vein. However, endoscopic vein ha... Objective: The great saphenous vein (GSV) is commonly used as a conduit for grafting during CABG surgery, and open GSV harvesting (OVH), commonly used with long incision to expose the vein. However, endoscopic vein harvesting (EVH) is an alternative approach, utilizing specialized instruments and small incisions to harvest the vein. Methods: A retrospective analysis was conducted on a cohort of patients who underwent Coronary artery bypass graft (CABG) requiring great saphenous vein (GSV) harvesting which was done by EVH or OVH procedures. Demographic variables, including age and gender, were assessed for both groups. Intraoperative variables such as the number of grafts, cardiopulmonary bypass time, X clamp time, and type of procedure were analyzed. Postoperative variables, including infection and bleeding rates, were also evaluated. Results: The study included 30 patients each undergoing Coronary artery bypass graft (CABG) with need of great saphenous vein harvesting which was done by EVH and OVH. Demographic variables were well-matched between the two groups in terms of age, while a significant difference in gender distribution was observed. Obesity and smoking were more prevalent in the OVH group, and EVH was associated with a higher mean number of grafts compared to OVH. Conversion to an open technique occurred in a portion of the EVH cases, and infection rates did not significantly differ between the EVH and OVH groups. However, the incidence of postoperative bleeding was significantly higher in the EVH group. Conclusion: This study provides valuable insights into the demographic, intraoperative, and postoperative variables associated with EVH and OVH techniques. EVH demonstrated advantages in terms of reduced infection rates compared to OVH. However, the higher incidence of postoperative bleeding associated with EVH raises concerns about potential risks. 展开更多
关键词 Endoscopic vein Harvesting (EVH) Open vein Harvesting (OVH) Coronary Artery Bypass Grafting (CABG) Great Saphenous vein (GSV) Surgical Outcomes
下载PDF
Application of the “Three Threes” Method in Clinical Teaching of Internal Jugular Vein Puncture
6
作者 Pengchao Cheng Wang Xi +3 位作者 Junnan Wang Jin Rao Yufeng Zhang Zhinong Wang 《Open Journal of Emergency Medicine》 2024年第1期10-17,共8页
Objective: To clarify the role of the “Three Threes” method in clinical teaching of internal jugular vein puncture and explore improvements in teaching methods. Methods: A doctor was assigned to the induction room o... Objective: To clarify the role of the “Three Threes” method in clinical teaching of internal jugular vein puncture and explore improvements in teaching methods. Methods: A doctor was assigned to the induction room of the Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital) for two months. The time required for catheterization, the first puncture success rate, and occurrence of puncture-related complications were compared before and after learning the “Three Threes” method. Results: Using the “Three Threes” method reduced the catheterization time by 43%, increased the first puncture success rate by 17%, and led to fewer puncture-related complications. Conclusion: The application of the “Three Threes” method not only improves the success rate of internal jugular vein puncture but also reduces complications, making it easier for students to master the technique. 展开更多
关键词 Internal Jugular vein Puncture “Three Threes” Method Deep vein Catheterization Teaching Practice
下载PDF
Automatic Detection and Characterization of Human Veins Using Infra-Red Image Processing
7
作者 Jean Ndoumbe Brice Ekobo Akoa +3 位作者 Gaelle Patricia Talotsing Frederic Franck Kounga Samuel Kaissassou Bertin Chouanmo Njo 《Journal of Computer and Communications》 2024年第9期141-159,共19页
The detection and characterization of human veins using infrared (IR) image processing have gained significant attention due to its potential applications in biometric identification, medical diagnostics, and vein-bas... The detection and characterization of human veins using infrared (IR) image processing have gained significant attention due to its potential applications in biometric identification, medical diagnostics, and vein-based authentication systems. This paper presents a low-cost approach for automatic detection and characterization of human veins from IR images. The proposed method uses image processing techniques including segmentation, feature extraction, and, pattern recognition algorithms. Initially, the IR images are preprocessed to enhance vein structures and reduce noise. Subsequently, a CLAHE algorithm is employed to extract vein regions based on their unique IR absorption properties. Features such as vein thickness, orientation, and branching patterns are extracted using mathematical morphology and directional filters. Finally, a classification framework is implemented to categorize veins and distinguish them from surrounding tissues or artifacts. A setup based on Raspberry Pi was used. Experimental results of IR images demonstrate the effectiveness and robustness of the proposed approach in accurately detecting and characterizing human. The developed system shows promising for integration into applications requiring reliable and secure identification based on vein patterns. Our work provides an effective and low-cost solution for nursing staff in low and middle-income countries to perform a safe and accurate venipuncture. 展开更多
关键词 vein Detection Blood Radiation Infrared Image CLAHE Algorithm Raspberry Pi
下载PDF
劈离式供肝儿童肝移植门静脉并发症的诊断与治疗 被引量:1
8
作者 曾凯宁 杨卿 +7 位作者 姚嘉 唐晖 傅斌生 冯啸 吕海金 易慧敏 易述红 杨扬 《器官移植》 CSCD 北大核心 2024年第1期63-69,共7页
目的探讨劈离式供肝儿童肝移植门静脉并发症的诊断及治疗策略。方法回顾性分析接受劈离式肝移植的88例儿童受者的临床资料。术中根据受者门静脉内径、发育情况,利用门静脉左右分支处进行吻合或间置供者髂静脉搭桥吻合,围手术期采用规范... 目的探讨劈离式供肝儿童肝移植门静脉并发症的诊断及治疗策略。方法回顾性分析接受劈离式肝移植的88例儿童受者的临床资料。术中根据受者门静脉内径、发育情况,利用门静脉左右分支处进行吻合或间置供者髂静脉搭桥吻合,围手术期采用规范化的门静脉血流监测,术后按肝素钠桥接华法林的方案进行抗凝治疗。经增强CT或门静脉造影确诊门静脉狭窄或血栓形成后,予切开取栓、全身抗凝、介入下取栓、球囊扩张和(或)支架置入等处理。结果88例受者中共10例患儿确诊门静脉并发症,其中4例门静脉狭窄,确诊时间分别为术后1 d、2个月、8个月、11个月,6例门静脉血栓形成,确诊时间分别为术中、术后2 d、术后3 d(2例)、术后6 d、术后11个月。1例门静脉狭窄者和1例门静脉血栓形成者于围手术期死亡,门静脉并发症相关病死率为2%(2/88)。其余8例患者中,1例行全身抗凝治疗、2例行门静脉切开取栓术、1例行介入下球囊扩张、4例行介入下球囊扩张及支架置入,术后均长期随访,未再出现门静脉相关症状,复查门静脉血流参数正常。结论规范化的术中及术后门静脉血流监测有助于早期发现门静脉并发症,及时采取术中门静脉切开取栓,术后介入下球囊扩张、支架置入等手段可有效治疗门静脉并发症,减少门静脉并发症导致的移植物丢失和受者死亡。 展开更多
关键词 儿童肝移植 劈离式肝移植 门静脉并发症 门静脉狭窄 门静脉血栓 活化部分凝血活酶时间 球囊扩张 支架置入
下载PDF
热液成矿系统构造控矿理论 被引量:8
9
作者 杨立强 杨伟 +6 位作者 张良 高雪 申世龙 王偲瑞 徐瀚涛 贾晓晨 邓军 《地学前缘》 EI CAS CSCD 北大核心 2024年第1期239-266,共28页
构造对成矿的控制是热液成矿系统的典型特征之一,系统剖析多重尺度控矿构造的几何学、运动学、动力学、流变学和热力学对认识矿床成因和预测找矿至关重要;而如何实现控矿构造格架、渗透性结构、成矿流体通道和矿化变形网络由静态到多尺... 构造对成矿的控制是热液成矿系统的典型特征之一,系统剖析多重尺度控矿构造的几何学、运动学、动力学、流变学和热力学对认识矿床成因和预测找矿至关重要;而如何实现控矿构造格架、渗透性结构、成矿流体通道和矿化变形网络由静态到多尺度时-空四维动态的转变,查明流体通道和矿床增量生长过程与控制因素,揭示热液成矿系统的构造-流体耦合成矿机制和定位规律是亟待解决的关键科学难题。为此,我们在对已有相关成果系统梳理的基础上,提出了科学构建热液成矿系统构造控矿理论的基本要点与对应方法及应用范畴:(1)流体而非构造是构造控矿理论的中心,热液系统的流体流动与成矿作用受控于断裂带格架及其渗透性结构,其中渗透率是将流体流动与流体压力变化联系起来理解控矿构造的核心;(2)不同控矿构造组合的关键控制是构造差应力和流体压力的大小,而矿化类型的变化可能是由于构造应力场引起的容矿构造方位的不同和赋矿围岩之间的强度差异所致;(3)流体通道的生长始于超压流体储库上游围岩中孤立的微裂隙沿流体压力梯度最大的方向、随裂隙发育且相互连结而形成新的长裂隙,并最终连通形成断裂网络内的流体通道,矿床的增量生长发生在高流体通量的短爆发期,断层反复滑动驱动其内流体压力、流速和应力快速变化,当由此诱发的流体通道生长破坏了流体系统的动态平衡时,随之而来的流体快速降压就成为金属沉淀成矿的关键驱动因素;(4)以热液裂隙-脉系统野外地质观测和构造-蚀变-矿化网络三维填图为基础,通过宏观与微观各级控矿构造相结合、地质历史与构造应力分析相结合、局部与区域点-线-面相结合、浅部与深部相结合、时间与空间相结合、定性和定量相结合,对各种控矿因素开展多学科、多尺度、多层次、全方位综合研究,是应遵循的基本原则;(5)通过构造-蚀变-矿化网络填图,将蚀变-矿化体与控矿构造的类型、形态、规模、产状和间距等几何学特征联系起来,利用热液裂隙-脉系统和断裂网络拓扑学及矿体三维几何结构分析等定量方法查明控矿构造格架和渗透性结构并揭示矿化变形网络的连通性与成矿潜力;(6)合理构建地质模型,选取合适的热力学参数和动力学边界条件,利用HCh和COMSOL等方法,定量模拟成矿过程中的流体流动、热-质传递、应力变形和化学反应等的时-空变化,是揭示构造-流体耦合成矿机理和定位规律、预测矿化中心和确定找矿目标的有效途径。进而提出了构造控矿理论的研究流程:聚焦构造-流体耦合成矿机制和定位规律这一关键科学问题,选择热液裂隙-脉系统和构造-蚀变-矿化网络为重点研究对象;通过几何学描述、运动学判断、流变学分析、动力学解析和热力学综合,厘定控矿构造格架,定位矿化中心,示踪成矿流体通道和多种矿化样式的增量生长过程及其关键控制,揭示渗透性结构的时-空演变规律及构造再活化与成矿定位的成因关联,建立构造-流体耦合成矿模式,服务新一轮战略找矿突破。以胶东焦家金矿田为例,开展控矿构造理论研究和成矿预测应用实践,证实了其科学性和有效性。 展开更多
关键词 热液裂隙-脉系统 构造-蚀变-矿化网络 渗透性结构与成矿定位 流体通道和矿床增量生长 构造-流体耦合成矿模式
下载PDF
颈静脉、锁骨下静脉汇入无名静脉区的影像解剖分型研究及其在中心静脉置管中的应用 被引量:1
10
作者 徐志宾 徐远 王鑫 《海南医学》 2024年第2期258-261,共4页
目的 研究双侧颈静脉、锁骨下静脉汇入无名静脉“三岔口”区的局部影像解剖并进行分型,初步探讨其在中心静脉置管中的应用。方法 河南科技大学第一附属医院2020年10月至2022年11月中心静脉置管病例389例,根据锁骨下静脉、颈静脉汇入无... 目的 研究双侧颈静脉、锁骨下静脉汇入无名静脉“三岔口”区的局部影像解剖并进行分型,初步探讨其在中心静脉置管中的应用。方法 河南科技大学第一附属医院2020年10月至2022年11月中心静脉置管病例389例,根据锁骨下静脉、颈静脉汇入无名静脉区局部影像解剖特点进行分型,右侧分为5型,左侧分为4型,结合置管后胸部X线片、CT检查、腔内心电及超声等资料明确中心静脉管位置,采用统计学方法分析“三岔口”区影像解剖分型与中心静脉导管异位的关系。结果 389例病例右侧“三岔口”区影像解剖分型中Ⅰ型占44.7%、Ⅱ型占24.7%、Ⅲ型占10.3%、Ⅳ型占17.2%、Ⅴ型占3.1%;左侧“三岔口”区影像解剖分型中Ⅰ型占29.3%、Ⅱ型占59.9%、Ⅲ型占9.8%、Ⅳ型占1.0%。经外周置入中心静脉导管(PICC)共271例,右侧入路180例中导管异位共24例,其中Ⅰ型3例、Ⅱ型5例、Ⅲ型4例、Ⅳ型7例、Ⅴ型5例,左侧入路91例中导管异位共3例,其中Ⅱ型2例、Ⅲ型1例;中心静脉导管异位发生率PICC右侧入路各型比较差异有统计学意义(χ^(2)=11.796,P=0.019),左侧入路各型比较差异无统计学意义(χ^(2)=2.073,P=0.557)。CVC置管118例,右侧入路104例中导管异位5例,其中Ⅱ型2例、Ⅲ型2例、Ⅳ型1例,左侧入路14例中导管异位3例,其中Ⅱ型2例、Ⅳ型1例,中心静脉导管异位发生率CVC右侧入路各型比较差异无统计学意义(χ^(2)=7.403,P=0.116),左侧入路各型比较差异无统计学意义(χ^(2)=4.497,P=0.213)。结论 颈静脉、锁骨下静脉汇入无名静脉区的影像解剖分型右侧Ⅰ型最多见,左侧Ⅱ型最多见,局部影像解剖分型与中心静脉导管异位存在一定关系。 展开更多
关键词 颈静脉 锁骨下静脉 无名静脉 影像解剖 经外周置入中心静脉导管 颈内静脉穿刺置入中心静脉导管
下载PDF
玻璃体腔注射雷珠单抗联合地塞米松缓释剂治疗视网膜静脉阻塞继发黄斑水肿 被引量:3
11
作者 朱晶 吴超琼 肖泽锋 《国际眼科杂志》 2024年第1期117-121,共5页
目的:比较玻璃体腔注射地塞米松缓释剂(Ozurdex)联合雷珠单抗治疗视网膜静脉阻塞继发黄斑水肿(RVO-ME)与单独使用雷珠单抗治疗的疗效及安全性的差异。方法:选取2020-06/2022-12就诊于我院经眼底血管荧光造影检查确诊为非缺血型RVO-ME的... 目的:比较玻璃体腔注射地塞米松缓释剂(Ozurdex)联合雷珠单抗治疗视网膜静脉阻塞继发黄斑水肿(RVO-ME)与单独使用雷珠单抗治疗的疗效及安全性的差异。方法:选取2020-06/2022-12就诊于我院经眼底血管荧光造影检查确诊为非缺血型RVO-ME的患者,所有患者先行玻璃体腔注射0.5 mg雷珠单抗注射液,2 wk后复查黄斑中心凹视网膜厚度(CRT)≥300μm的42例42眼患者纳入研究,随机分为联合治疗组(21例21眼,即时给予玻璃体腔内注射地塞米松缓释剂)及单药治疗组[21例21眼,仍继续按3+按需(PRN)方式行雷珠单抗注射治疗]。观察治疗前及分组治疗后2 wk,1、2、3、4、5、6 mo的最佳矫正视力(BCVA)、CRT及眼压的改变,并观察眼部及全身并发症的发生情况。结果:分组治疗后2 wk,1、2、3、4、5、6 mo,两组患者BCVA及CRT的改善程度较治疗前显著好转(均P<0.01);治疗后2、3 mo,两组间BCVA及CRT比较有差异(均P<0.05),治疗后2 mo时联合治疗组BCVA字母数增加最明显。单药治疗组黄斑水肿平均复发时间为1.45±0.53 mo,雷珠单抗注射平均4.21±0.78次,两组患者治疗后均未见严重并发症。联合治疗组最常见的并发症为结膜下出血和眼压升高,局部使用降压药后眼压可控制,没有患者需接受抗青光眼及白内障手术。结论:玻璃体腔注射地塞米松缓释剂联合雷珠单抗治疗RVO-ME与单独使用雷珠单抗治疗相比,能显著提高患者的视力,有效减轻黄斑水肿,疗效持续时间长,可有效减少玻璃体腔注药次数。 展开更多
关键词 地塞米松缓释剂 雷珠单抗注射液 血管内皮生长因子 视网膜静脉阻塞 黄斑水肿 玻璃体腔注射
下载PDF
多元化健康教育模式在预防下肢骨折患者深静脉血栓中的应用 被引量:1
12
作者 李明 陈铮 +6 位作者 王晓彦 张佳琦 张娇 张晶 薛慧 李秀婷 邸禄芹 《河北医药》 CAS 2024年第5期790-793,共4页
目的探讨多元化健康教育模式在预防下肢骨折患者深静脉血栓中的应用效果。方法采用便利抽样法,选取2021年1~12月收治的下肢骨折患者300例,按照住院时间将2021年1~6月收治的患者作为对照组,将2021年7~12月收治的患者作为观察组,每组150... 目的探讨多元化健康教育模式在预防下肢骨折患者深静脉血栓中的应用效果。方法采用便利抽样法,选取2021年1~12月收治的下肢骨折患者300例,按照住院时间将2021年1~6月收治的患者作为对照组,将2021年7~12月收治的患者作为观察组,每组150例。对照组采用常规健康教育模式,观察组采用多元化健康教育模式。比较2组患者对深静脉血栓的认知水平、基本预防措施依从性、深静脉血栓的发生率,以及患者对护理工作满意度。结果观察组患者对深静脉血栓的认知水平、对基本预防措施的依从性、护理满意度显著高于对照组(P<0.05)。观察组患者深静脉血栓发生率为16.00%低于对照组的25.33%,差异有统计学意义(P<0.05)。结论将多元化健康教育模式应用于下肢骨折患者,可提高护理效果,降低深静脉血栓的发生率,值得推广应用。 展开更多
关键词 多元化健康教育 下肢骨折 深静脉血栓 依从性
下载PDF
丹参片联合那屈肝素钙注射液对髋部骨折术后下肢静脉血流参数的影响 被引量:1
13
作者 王晓亚 杨淑仙 +7 位作者 王浩 任猛 李文夺 李金涛 刘建军 刘西斌 任宝 左静 《河北医药》 CAS 2024年第2期243-246,共4页
目的探讨丹参片联合那屈肝素钙注射液对髋部骨折术后下肢静脉血流参数的影响。方法将2021年12月至2022年12月接受髋部骨折手术治疗的108例患者作为研究对象,按随机数字表法分为对照组和观察组,每组54例,2组均在术后开始用药,对照组采用... 目的探讨丹参片联合那屈肝素钙注射液对髋部骨折术后下肢静脉血流参数的影响。方法将2021年12月至2022年12月接受髋部骨折手术治疗的108例患者作为研究对象,按随机数字表法分为对照组和观察组,每组54例,2组均在术后开始用药,对照组采用那屈肝素钙注射液治疗,观察组采用丹参片联合那屈肝素钙注射液治疗,2组均治疗7 d后,对比术前及术后7 d患肢小腿直径差,对比术前及术后7 d疼痛分级(NRS)、下肢静脉血流参数(股总静脉、股浅静脉、股深静脉)、凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、骨碱性磷酸酶(BALP)、骨钙素(BGP)、Ⅰ型胶原羧基端交联肽(CTX-1),比较2组术后下肢静脉血栓发生率、药物不良发生率。结果观察组术前及术后7 d患肢小腿直径差明显低于对照组,NRS评分低于术前及对照组术后7 d,差异均有统计学意义(P<0.05);术后7 d观察组股总静脉、股浅静脉、股深静脉参数、TT、PT、APTT、BALP、BGP水平明显高于术前及对照组术后7天,CTX-1水平明显低于术前及对照组术后7天,差异均有统计学意义(P<0.05);2组不良反应总发生率比较,差异无统计学意义(P>0.05);观察组下肢脉血栓发生率明显低于对照组(P<0.05)。结论丹参片联合那屈肝素钙注射液用于髋部骨折术后,能缓解患者肿胀及疼痛,加快下肢静脉血流,降低患者血液高凝状态,改善骨代谢指标,进而降低血栓发生率。 展开更多
关键词 丹参片 那屈肝素钙注射液 髋部骨折术 下肢静脉血流参数
下载PDF
基于诺莫图构建髋部骨折患者发生下肢深静脉血栓的预测模型 被引量:1
14
作者 王银平 杜雪莲 +4 位作者 王亮云 黄瑞珍 罗乙舒 熊俊琴 何丽连 《广东药科大学学报》 CAS 2024年第2期144-149,共6页
目的探讨髋部骨折患者发生下肢深静脉血栓(DVT)的独立危险因素,并构建和验证列线图模型。方法选择2020年1月至2023年6月佛山市中医院骨科收治的髋部骨折患者227例为研究对象,按照7∶3比例将患者分为建模组(n=159)和验证组(n=68)。收集... 目的探讨髋部骨折患者发生下肢深静脉血栓(DVT)的独立危险因素,并构建和验证列线图模型。方法选择2020年1月至2023年6月佛山市中医院骨科收治的髋部骨折患者227例为研究对象,按照7∶3比例将患者分为建模组(n=159)和验证组(n=68)。收集患者的临床资料,采用LASSO回归和Logistic回归筛选髋部骨折患者发生DVT的独立危险因素,建立风险预测模型和列线图。采用一致性指数(C-index)、校准曲线、受试者工作特征(ROC)曲线进行评价。结果建模组159例髋部骨折中发生DVT 33例,发生率为20.89%。LASSO回归结合多因素Logistic回归分析结果显示,年龄≥70岁、糖尿病、受伤至手术时间≥5 d、低蛋白血症、D-二聚体>0.5是髋部骨折患者发生DVT的独立危险因素。基于上述危险因素绘制列线图模型,将上述5个危险因素构建列线图模型,模型区分度良好(C-index=0.932);Hosmer-Lemeshow检验显示,列线图的拟合优度良好(χ^(2)=57.625,P=0.732)。建模组和验证组发生DVT的ROC曲线下面积分别为0.932、0.821,模型准确度高。结论年龄≥70岁、糖尿病、受伤至手术时间≥5 d、低蛋白血症、D-二聚体>0.5是髋部骨折患者发生DVT的独立危险因素,基于上述因子构建的列线图模型可有效预测髋部骨折患者发生DVT的风险。 展开更多
关键词 髋部骨折 下肢深静脉血栓 危险因素 列线图
下载PDF
全麻患者术后麻醉重症监护室中新发下肢深静脉血栓的危险因素 被引量:1
15
作者 王晓飞 孙铭阳 张加强 《临床麻醉学杂志》 CAS CSCD 北大核心 2024年第1期56-60,共5页
目的筛选全麻术后转入麻醉重症监护室(AICU)的患者新发下肢深静脉血栓(DVT)的危险因素。方法回顾性收集2022年5—8月择期行全麻下手术后带气管插管转入AICU的患者192例,男105例,女87例,年龄18~85岁,BMI 18~31 kg/m^(2),ASAⅡ或Ⅲ级。收... 目的筛选全麻术后转入麻醉重症监护室(AICU)的患者新发下肢深静脉血栓(DVT)的危险因素。方法回顾性收集2022年5—8月择期行全麻下手术后带气管插管转入AICU的患者192例,男105例,女87例,年龄18~85岁,BMI 18~31 kg/m^(2),ASAⅡ或Ⅲ级。收集患者基线资料、麻醉手术资料及实验室检查资料。根据入AICU 6 h内的超声结果是否有新发DVT将患者分为两组:DVT组和非DVT组。采用多因素Logistic回归分析筛选AICU中患者术后6 h内新发DVT的危险因素及其95%可信区间(CI)。结果全麻术后在AICU新发DVT的患者有64例(33.3%),均为小腿肌间静脉血栓(CMVT)。多因素Logistic回归分析结果显示,术前心律失常(OR=2.236,95%CI 1.011~4.943,P=0.047)、术前血小板计数高(OR=1.006,95%CI 1.002~1.010,P=0.007)、术前D⁃二聚体浓度高(OR=1.203,95%CI 1.046~1.383,P=0.010)、术中低血压(OR=1.010,95%CI 1.002~1.019,P=0.020)和术中应用去甲肾上腺素(OR=3.796,95%CI 1.697~8.492,P=0.001)是全麻术后AICU中患者新发DVT的危险因素;阿司匹林规律服用史(OR=0.176,95%CI 0.060~0.518,P=0.002)是其保护因素。结论术前心律失常、术前血小板计数高、术前D⁃二聚体浓度高、术中低血压及术中应用去甲肾上腺素是全麻手术后AICU患者6 h内新发DVT的危险因素。 展开更多
关键词 下肢深静脉血栓 全麻 麻醉重症监护室 危险因素
下载PDF
视网膜静脉阻塞继发黄斑水肿患者基线房水细胞因子水平与抗VEGF疗效的相关性 被引量:1
16
作者 黄颖 陈佳沁 +1 位作者 蒋沁 姚进 《眼科新进展》 CAS 北大核心 2024年第1期39-43,共5页
目的利用基线房水细胞因子预测视网膜静脉阻塞继发黄斑水肿(RVO-ME)患者抗血管内皮生长因子(VEGF)治疗3个月后黄斑中心凹厚度(CMT)和最佳矫正视力(BCVA)的改善情况。方法选择2021年10月至2023年1月在南京医科大学附属眼科医院首诊为RVO... 目的利用基线房水细胞因子预测视网膜静脉阻塞继发黄斑水肿(RVO-ME)患者抗血管内皮生长因子(VEGF)治疗3个月后黄斑中心凹厚度(CMT)和最佳矫正视力(BCVA)的改善情况。方法选择2021年10月至2023年1月在南京医科大学附属眼科医院首诊为RVO-ME的患者30例(30眼),在抗VEGF药物注射前行前房穿刺收集房水。采用Luminex液相芯片技术测定患者房水中VEGF、细胞间黏附分子-1(ICAM-1)、白细胞介素(IL)和干扰素-γ(IFN-γ)等11种细胞因子的水平。分析RVO-ME患者基线房水细胞因子水平与CMT、BCVA(logMAR)以及其变化值(基线与抗VEGF治疗3个月后差值)的相关性;在基线时与抗VEGF治疗3个月后分别分析CMT和BCVA(logMAR)间的相关性。CMT、BCVA应答者定义为从基线到抗VEGF治疗3个月后CMT、BCVA(logMAR)减少50%及以上的患者,使用Logistic回归模型分析基线房水细胞因子与RVO-ME患者抗VEGF治疗3个月后成为CMT或BCVA应答者的关系。结果与基线时相比,抗VEGF治疗3个月后RVO-ME患者CMT明显下降,BCVA明显改善(均为P<0.001)。RVO-ME患者基线时、抗VEGF治疗3个月后CMT与BCVA(logMAR)之间均呈正相关(P=0.026、0.002)。基线时,RVO-ME患者VEGF、IL-8水平与CMT均呈正相关(P=0.032、0.035);IL-6、IL-8水平与BCVA(logMAR)均呈正相关(P=0.018、0.002)。RVO-ME患者基线IL-8水平与CMT变化值呈负相关(P=0.024)。Logistic回归分析结果表明,基线ICAM-1水平升高增加RVO-ME患者抗VEGF治疗3个月后BCVA无应答的风险(P=0.023)。结论基线IL-8与ICAM-1可能是RVO-ME抗VEGF治疗后CMT及BCVA改善的预测因子。 展开更多
关键词 视网膜静脉阻塞 黄斑水肿 房水 细胞因子 黄斑中心凹厚度 最佳矫正视力
下载PDF
乳腺癌患者外周中心静脉导管相关上肢深静脉血栓形成的抗凝治疗 被引量:1
17
作者 李伟 陈占 +2 位作者 鲁磊 王冰涛 尚宏清 《血管与腔内血管外科杂志》 2024年第3期327-331,共5页
目的总结分析乳腺癌患者发生外周中心静脉导管(PICC)相关上肢深静脉血栓(DVT)形成的诊治经验。方法收集2021年6月至2023年3月北京市海淀医院收治的发生PICC相关上肢DVT的134例乳腺癌患者的临床资料,根据抗凝治疗方案的不同将患者分为低... 目的总结分析乳腺癌患者发生外周中心静脉导管(PICC)相关上肢深静脉血栓(DVT)形成的诊治经验。方法收集2021年6月至2023年3月北京市海淀医院收治的发生PICC相关上肢DVT的134例乳腺癌患者的临床资料,根据抗凝治疗方案的不同将患者分为低分子肝素组(n=65)和利伐沙班组(n=69)。比较两组患者的乳腺癌专科信息和启动抗凝治疗后3个月的随访结果。结果两组患者的临床分期、肿瘤部位、手术情况、放疗情况比较,差异均无统计学意义(P﹥0.05)。治疗后3个月随访结果显示,两组患者的导管功能失用率、上肢DVT复发率、出血发生率比较,差异均无统计学意义(P﹥0.05)。两组患者均发生了轻微出血。治疗前,两组患者的D-二聚体水平比较,差异无统计学意义(P﹥0.05);治疗后4、12周,两组患者的D-二聚体水平均较本组治疗前下降,差异均有统计学意义(P﹤0.05),但两组患者的D-二聚体水平比较,差异均无统计学意义(P﹥0.05)。结论低分子肝素与利伐沙班治疗乳腺癌患者PICC相关上肢DVT的疗效与安全性相当,但利伐沙班可能更方便患者出院后使用。 展开更多
关键词 乳腺癌 外周中心静脉导管 深静脉血栓 低分子肝素 利伐沙班
下载PDF
一种新的临时心脏起搏器置入方法及综合护理策略 被引量:1
18
作者 黄慧卿 吴斌斌 +3 位作者 黄峥嵘 李卫华 张雪好 何德化 《循证护理》 2024年第3期512-516,共5页
目的:探讨经肘正中静脉行临时心脏起搏器置入术的可行性、安全性、舒适度和情感差异,并总结相应的综合护理策略。方法:选取2020年6月—2022年3月于我院行临时心脏起搏器置入术病人136例,采用随机数字表法分为股静脉组(F组)和肘正中静脉... 目的:探讨经肘正中静脉行临时心脏起搏器置入术的可行性、安全性、舒适度和情感差异,并总结相应的综合护理策略。方法:选取2020年6月—2022年3月于我院行临时心脏起搏器置入术病人136例,采用随机数字表法分为股静脉组(F组)和肘正中静脉组(M组),各68例。统计两组病人的手术成功率、电极脱位率以及并发症发生率,并采用Kolcaba舒适状况量表(GCQ)、Zung焦虑自评量表(SAS)和Zung抑郁自评量表(SDS)进行舒适状况评价及情感评定,总结综合护理经验。结果:两组病人手术均成功,与M组比较,F组的电极脱位率和并发症发生率更高(P<0.05)。术后,与F组比较,M组GCQ评分更高(P<0.05),而SAS评分和SDS评分更低(P<0.05),相应的护理策略可以改善M组病人GCQ评分,差异均有统计学意义(P<0.05),但对F组GCQ改善不明显,差异无统计学意义(P>0.05);同时两组SAS评分和SDS评分均进一步降低,差异有统计学意义(P<0.05)。结论:与传统股静脉路径比较,经肘正中静脉置入临时心脏起搏器疗效确切,安全性更高、舒适度更佳且情绪更平稳,辅助于综合护理对病人获益更大。 展开更多
关键词 起搏器 肘正中静脉 舒适度 心理 心脏病 护理
下载PDF
儿童血液净化股静脉置管并发症风险预测模型的构建与验证 被引量:1
19
作者 张胜华 江雨秋 +3 位作者 李银 宋诗怡 唐静 胡燕 《中国血液净化》 CSCD 2024年第1期62-66,共5页
目的首次构建儿童血液净化股静脉置管并发症的风险预测模型,并验证预测效果。方法选取2020年1月—2022年6月四川大学华西第二医院小儿肾脏科使用股静脉置管行血液净化治疗的患儿428例,行单因素和多因素Logistic回归分析股静脉置管并发... 目的首次构建儿童血液净化股静脉置管并发症的风险预测模型,并验证预测效果。方法选取2020年1月—2022年6月四川大学华西第二医院小儿肾脏科使用股静脉置管行血液净化治疗的患儿428例,行单因素和多因素Logistic回归分析股静脉置管并发症发生的危险因素,建立风险预测模型并使用列线图展示模型。采用ROC曲线、校准曲线评价模型的区分度和校准度,以2022年7月—10月50例患儿资料进行模型的外部验证。结果病因肾衰竭(OR=5.041,95%CI:1.170~21.726,P=0.030)、合并低白蛋白血症(OR=2.963,95%CI:1.090~8.057,P=0.033)、躁动(OR=2.871,95%CI:1.159~7.109,P=0.023)、双下肢水肿(OR=2.359,95%CI:1.052~5.288,P=0.037)、高血压(OR=2.473,95%CI:0.010~6.057,P=0.048)、腹腔积液(OR=5.673,95%CI:2.242~14.357,P<0.001)以及输注血/血制品(OR=2.693,95%CI:1.0697~6.612,P=0.031)是儿童血液净化股静脉置管并发症的独立危险因素。预测模型ROC曲线下面积(AUC)为0.794(95%CI:0.738~0.851,P<0.001),灵敏度为0.733,特异度为0.725,最大约登指数为0.458,预测模型拟合优势比χ^(2)=3.395,P=0.907。依据验证组所建模型预测概率绘制ROC曲线,AUC为0.810(P<0.001,95%CI:0.689~0.931),灵敏度为0.739,特异度为0.778。结论本研究构建的预测模型能较好地预测儿童血液净化股静脉置管并发症的发生风险,可为医护人员早期识别高危患儿,采取有效措施预防并发症的发生提供参考。 展开更多
关键词 儿童 血液净化 股静脉置管 并发症 危险因素 预测模型
下载PDF
无痛诊疗技术在超声PICC置管患儿中的应用效果研究 被引量:1
20
作者 黄亚利 王香红 +4 位作者 李洪辛 易琼 丛丹 方原 李若星 《中国现代医生》 2024年第5期87-90,共4页
目的探讨无痛诊疗技术在超声引导下儿童经外周静脉穿刺中心静脉置管术(peripherally inserted central catheter,PICC)中的应用效果。方法选取笔者医院2021年1月至2023年1月拟行PICC的患儿82例,用随机数字表法将其分为对照组、观察组,每... 目的探讨无痛诊疗技术在超声引导下儿童经外周静脉穿刺中心静脉置管术(peripherally inserted central catheter,PICC)中的应用效果。方法选取笔者医院2021年1月至2023年1月拟行PICC的患儿82例,用随机数字表法将其分为对照组、观察组,每组41例;对照组行常规超声引导下PICC置管术,观察组行无痛诊疗技术超声引导下PICC置管术;对比两组置管成功率、置管完成时间,患儿疼痛程度[儿童疼痛行为量表(children’s pain behavior scale,FLACC)],耐受度[Houpt行为量表(Houpt behavior scale,HBS)],依从性[Frankl量表(Frankl scale,FCS)]及家属满意度。结果观察组置管成功率较对照组高,置管时间较对照组短,差异有统计学意义(P<0.05);观察组FLACC评分较对照组低,HBS评分、FCS评分较对照组高,差异有统计学意义(P<0.05);观察组家属总满意度较对照组高,差异有统计学意义(P<0.05)。结论无痛诊疗技术用于超声引导下儿童PICC置管术可提高置管成功率,缩短置管时间,减轻患儿疼痛程度,增强耐受性、依从性,提升家属满意度。 展开更多
关键词 经外周静脉穿刺中心静脉置管术 超声 无痛诊疗技术
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部