Two kinds of chiral monomers,(-)α-phenylethyl-acrylamide and(-)α phenylethyl-10-undecendyl amide,were synthesized via consendation of(S)-α-phenyl ethyl amine and acryl chloride or 10-undecendyl chloride.Their struc...Two kinds of chiral monomers,(-)α-phenylethyl-acrylamide and(-)α phenylethyl-10-undecendyl amide,were synthesized via consendation of(S)-α-phenyl ethyl amine and acryl chloride or 10-undecendyl chloride.Their structures and purities were determined via IR,1H NMR and elemental analysis.The seeded microspheres of polystyrene(about 3 μm) were prepared with dispersion polymerization,and monodisperse hollow chiral polymer microspheres were prepared with two-stage swelling procedure via copolymerization of styrene,divinyl benzene and the chiral monomers synthesized above.The average diameter of the microsphere was about 10 μm.The chiral polymer microspheres were used to be the stationary phase of HPLC.The molar ratio of(S)-α-ethyl hydroxy phenylbutyrate and(R)-α-ethylhydroxy phenylbutyrate were determined via chiral HPLC.The chromatography results showed that the chiral recognition was very higy when using chiral polymer microsphere,prepared by S-10-undecylenoyl(α-phenyl)ethylamide as chiral monomer,as chiral stationary phase of HPLC.展开更多
The crystal structure of the title compound C_12H_18NO_6P has been determined by X-ray diffraction methods. It belongs to orthorhombic space group Pabc with cell parameters: a=10. 708(5), b=16.151(4), c=17. 615(2) A, ...The crystal structure of the title compound C_12H_18NO_6P has been determined by X-ray diffraction methods. It belongs to orthorhombic space group Pabc with cell parameters: a=10. 708(5), b=16.151(4), c=17. 615(2) A, V=3046. 4 A￣3, Z=8, D_c= 1. 39 g/cm￣3, F(000)=1280, μ=29. 77cm￣(-1) (CuKα), M_r= 303. 25 ,R=0. 065, R_w= 0. 055. In the molecule, the P atom is coordinated by three O and one C atoms with a distorted tetrahedral configuration.展开更多
文摘Two kinds of chiral monomers,(-)α-phenylethyl-acrylamide and(-)α phenylethyl-10-undecendyl amide,were synthesized via consendation of(S)-α-phenyl ethyl amine and acryl chloride or 10-undecendyl chloride.Their structures and purities were determined via IR,1H NMR and elemental analysis.The seeded microspheres of polystyrene(about 3 μm) were prepared with dispersion polymerization,and monodisperse hollow chiral polymer microspheres were prepared with two-stage swelling procedure via copolymerization of styrene,divinyl benzene and the chiral monomers synthesized above.The average diameter of the microsphere was about 10 μm.The chiral polymer microspheres were used to be the stationary phase of HPLC.The molar ratio of(S)-α-ethyl hydroxy phenylbutyrate and(R)-α-ethylhydroxy phenylbutyrate were determined via chiral HPLC.The chromatography results showed that the chiral recognition was very higy when using chiral polymer microsphere,prepared by S-10-undecylenoyl(α-phenyl)ethylamide as chiral monomer,as chiral stationary phase of HPLC.
文摘The crystal structure of the title compound C_12H_18NO_6P has been determined by X-ray diffraction methods. It belongs to orthorhombic space group Pabc with cell parameters: a=10. 708(5), b=16.151(4), c=17. 615(2) A, V=3046. 4 A￣3, Z=8, D_c= 1. 39 g/cm￣3, F(000)=1280, μ=29. 77cm￣(-1) (CuKα), M_r= 303. 25 ,R=0. 065, R_w= 0. 055. In the molecule, the P atom is coordinated by three O and one C atoms with a distorted tetrahedral configuration.
