Alpha-1-antitrypsin deficiency resulting in a hitherto unseen presentation of hepatocellular carcinoma:Polycythemia but with normal alpha fetoprotein

Polycythemia is a known paraneopastic manifestation of hepatoma, but only in the presence of alpha-fetopro （AFP）. We present a case of polycythemia in the absence of AFP, and suggest concurrent alpha-1-antitrypsin deficiency as the cause for breaking this rule. We also suggest a reason for the apparent constant conjunction between polycythemia and AFP in hepatoma.

乙酰半胱氨酸泡腾片对百草枯中毒患者肺纤维化改善的研究

目的:研究乙酰半胱氨酸泡腾片对百草枯中毒患者肺纤维化的改善。方法:百草枯中毒患者60例随机分成治疗组30例,对照组30例,治疗组在常规治疗基础上加用乙酰半胱氨酸泡腾片治疗。结果:治疗组治疗后体内α-1酶抗胰蛋白(α1-AT)、谷胱甘肽(GSH)升高程度明显优于对照组,而且随着用药时间的延长检测浓度也越高。治疗前后自身对照差异有显著性(P<0.05﹚。结论:乙酰半胱氨酸泡腾片能控制肺纤维化的发生和发展,可作为治疗百草枯中毒的有效手段之一。