In the presence of diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate（DHP） and a catalytic amount of potassium iodide,severalα-halo ketones were easily reduced to the corresponding ketones in acetone media....In the presence of diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate（DHP） and a catalytic amount of potassium iodide,severalα-halo ketones were easily reduced to the corresponding ketones in acetone media.The procedure presented here showed several merits such as short reaction time,practical experimental and isolated procedure,and excellent yields of products.展开更多
The sequential oxidation-Horner-Wadsworth-Emmons reaction of alcohols to prepare α-Halo-α,β-unsaturated esters （halo =F, Cl） with middle to excellent （Z）-selectivity was developed.
Due to the chemoselective dehalogenation by SmI2, the addition of α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfones gave the products in moderate to ...Due to the chemoselective dehalogenation by SmI2, the addition of α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfones gave the products in moderate to good yields. The SmI2-mediat-ed addition of gem-dihalomethylsulfones to ketones also afforded α-halo-β-hydroxysulfones in moderate yields.展开更多
应用一种扩展的分子动力学模型(Extension of quantum molecular dynamics,EQMD)研究了轻核的晕结构和团簇结构。对于晕结构,详细讨论了晕结构核在EQMD模型框架下的初始化,给出了14Be、17B、19C和22C的晕核结构性质和物质密度分布,讨论...应用一种扩展的分子动力学模型(Extension of quantum molecular dynamics,EQMD)研究了轻核的晕结构和团簇结构。对于晕结构,详细讨论了晕结构核在EQMD模型框架下的初始化,给出了14Be、17B、19C和22C的晕核结构性质和物质密度分布,讨论了价中子波包宽度、核芯核子的波包宽度以及核芯的形态对于晕结构存在的重要性。对于团簇结构,给出了EQMD模型框架下对于轻的4n核的α团簇态的描述结果,讨论了不同团簇态的稳定性、结合能以及不同核子的波包宽度,指出了团簇态在自由演化过程中的α之间能量流动性质。并讨论了4-α正四面体结构作为16O基态的可能性。展开更多
Halogenation of the potassium or silver salts of bis(trifluoromethanesulfonyl)methane (CF3SO2)2CH2 and its cyclo analogues 1 with N-fluoro-bis(trifluoromethanesulfonyl)imine [(CF3SO3)2NF], chlorine or bromine gave goo...Halogenation of the potassium or silver salts of bis(trifluoromethanesulfonyl)methane (CF3SO2)2CH2 and its cyclo analogues 1 with N-fluoro-bis(trifluoromethanesulfonyl)imine [(CF3SO3)2NF], chlorine or bromine gave good yields of the corresponding α-halo disulfone (CF3SO2)2CHX and cyclo analogues 9, 10. The chemical transformation of these fluorinated α-halo-disulfones are described.展开更多
The hydrohalogenation reaction of 1-alkyl substituted 1,2-allenyl carboxylic acid esters (1) with MX (M= Na, or Li, X= Cl, Br, I) afforded a mixture of β,γ-unsaturated 3-halo–3-alkenoates (2) and Q,P unsaturated 3-...The hydrohalogenation reaction of 1-alkyl substituted 1,2-allenyl carboxylic acid esters (1) with MX (M= Na, or Li, X= Cl, Br, I) afforded a mixture of β,γ-unsaturated 3-halo–3-alkenoates (2) and Q,P unsaturated 3-halo-2-alkenoates (3) in HOAc, while using a mixture of HOAC-CF3CO2H (1:1) or CF3C2H as the reaction medium the corresponding reaction cleanly produced β,γ -unsaturated 3-hale3-alkenoates (2) as the sole products in high yields. The subsequent coupling reactions were studied.展开更多
基金the Guangdong Natural Science Foundation(No.8151063201000016)the National Natural Science Foundation of China(No.20672046) for financial support
文摘In the presence of diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate（DHP） and a catalytic amount of potassium iodide,severalα-halo ketones were easily reduced to the corresponding ketones in acetone media.The procedure presented here showed several merits such as short reaction time,practical experimental and isolated procedure,and excellent yields of products.
文摘The sequential oxidation-Horner-Wadsworth-Emmons reaction of alcohols to prepare α-Halo-α,β-unsaturated esters （halo =F, Cl） with middle to excellent （Z）-selectivity was developed.
基金Project supported by the National Natural Science Foundation of China(No.20272050).
文摘Due to the chemoselective dehalogenation by SmI2, the addition of α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfones gave the products in moderate to good yields. The SmI2-mediat-ed addition of gem-dihalomethylsulfones to ketones also afforded α-halo-β-hydroxysulfones in moderate yields.
基金Project supported by the National Natural Science Foundation of China(No.21362002)the Bagui Scholar Program of Guangxi Province of China(No.2016A13)~~
文摘应用一种扩展的分子动力学模型(Extension of quantum molecular dynamics,EQMD)研究了轻核的晕结构和团簇结构。对于晕结构,详细讨论了晕结构核在EQMD模型框架下的初始化,给出了14Be、17B、19C和22C的晕核结构性质和物质密度分布,讨论了价中子波包宽度、核芯核子的波包宽度以及核芯的形态对于晕结构存在的重要性。对于团簇结构,给出了EQMD模型框架下对于轻的4n核的α团簇态的描述结果,讨论了不同团簇态的稳定性、结合能以及不同核子的波包宽度,指出了团簇态在自由演化过程中的α之间能量流动性质。并讨论了4-α正四面体结构作为16O基态的可能性。
基金Project (No. 29632003 and No. 29672041) supported by the National Natural Science Foundation of China.
文摘Halogenation of the potassium or silver salts of bis(trifluoromethanesulfonyl)methane (CF3SO2)2CH2 and its cyclo analogues 1 with N-fluoro-bis(trifluoromethanesulfonyl)imine [(CF3SO3)2NF], chlorine or bromine gave good yields of the corresponding α-halo disulfone (CF3SO2)2CHX and cyclo analogues 9, 10. The chemical transformation of these fluorinated α-halo-disulfones are described.
基金National Natural Science Foundation of China (No. 29525202)Shanghai Municipal Cormnittee of Science and Technology (No. 98QA14001).
文摘The hydrohalogenation reaction of 1-alkyl substituted 1,2-allenyl carboxylic acid esters (1) with MX (M= Na, or Li, X= Cl, Br, I) afforded a mixture of β,γ-unsaturated 3-halo–3-alkenoates (2) and Q,P unsaturated 3-halo-2-alkenoates (3) in HOAc, while using a mixture of HOAC-CF3CO2H (1:1) or CF3C2H as the reaction medium the corresponding reaction cleanly produced β,γ -unsaturated 3-hale3-alkenoates (2) as the sole products in high yields. The subsequent coupling reactions were studied.
