Objective To study the mechanism of glucose transporting by the way of in different blood state myocardium.Methods The expression of GLUT4、 GLUT1 was dectected with Western blotting analysis.Results GLUT4、GLUT1 was ...Objective To study the mechanism of glucose transporting by the way of in different blood state myocardium.Methods The expression of GLUT4、 GLUT1 was dectected with Western blotting analysis.Results GLUT4、GLUT1 was increased when phenylephrine was used before ischemia. During ischemia,GLUT4、GLUT1 was increased. Phenylephrine given during repefusin increased GLUT4、GLUT1.Prazosin given during ischemia,GLUT4、GLUT1 was reduced. During reperfusion,GLUT4、GLUT1 was decreased.Conclusion Changing the expression of GLUT4、 GLUT1,adjustting transporting of glucose,controlling glucose transport in different states of cardiac muscle cell by α1-adrenoceptors.展开更多
文摘Objective To study the mechanism of glucose transporting by the way of in different blood state myocardium.Methods The expression of GLUT4、 GLUT1 was dectected with Western blotting analysis.Results GLUT4、GLUT1 was increased when phenylephrine was used before ischemia. During ischemia,GLUT4、GLUT1 was increased. Phenylephrine given during repefusin increased GLUT4、GLUT1.Prazosin given during ischemia,GLUT4、GLUT1 was reduced. During reperfusion,GLUT4、GLUT1 was decreased.Conclusion Changing the expression of GLUT4、 GLUT1,adjustting transporting of glucose,controlling glucose transport in different states of cardiac muscle cell by α1-adrenoceptors.
