The secondary structures of proteins fall into two classes: regular structure and nonregular structure. Helices and sheets are termed 'regular' structures because their residues have repeating main-chain torsi...The secondary structures of proteins fall into two classes: regular structure and nonregular structure. Helices and sheets are termed 'regular' structures because their residues have repeating main-chain torsion angles, and their backbone N-H and C-O groups are arranged in a periodic pattern of hydrogen bonding. In contrast, the remaining structures with nonrepeating backbone torsion angles are called nonregular secondary structures. In this note, we performed an extensive sequence analysis of nonregular secondary structures and showed that these nonregular parts could be effectively predicted by continuous wavelet transform.展开更多
基金This work was supported by the National Natural Science Foundation of China (Grant No. 39870171).
文摘The secondary structures of proteins fall into two classes: regular structure and nonregular structure. Helices and sheets are termed 'regular' structures because their residues have repeating main-chain torsion angles, and their backbone N-H and C-O groups are arranged in a periodic pattern of hydrogen bonding. In contrast, the remaining structures with nonrepeating backbone torsion angles are called nonregular secondary structures. In this note, we performed an extensive sequence analysis of nonregular secondary structures and showed that these nonregular parts could be effectively predicted by continuous wavelet transform.
