The effects of opioid peptides on iminune responses were investigated. It was found that β-endorphin (β-END) can depress proliferative responses to PHA in rat splenocytes but enhance those in mice, and it could also...The effects of opioid peptides on iminune responses were investigated. It was found that β-endorphin (β-END) can depress proliferative responses to PHA in rat splenocytes but enhance those in mice, and it could also inhibit the plaque-forming cell (PFC) response to sheep red blood cells when mouse splenocytes immunized in vivo were cultured in vitro with the peptide. The peptide antagonist naloxone was able to reverse β-END suppression of the PFC response. The data indicate that β-END suppresses antibody production or secretion via a specific opioidreceptor-mediated mechanism.展开更多
Objective： To investigate the clinical efficacy and immunological mechanism of herbal cake-partitioned moxibustion for aging process. Method： The herbal cake-partitioned moxibustion was adopted for 223 cases to obse...Objective： To investigate the clinical efficacy and immunological mechanism of herbal cake-partitioned moxibustion for aging process. Method： The herbal cake-partitioned moxibustion was adopted for 223 cases to observe the aging scores before and after the treatment. Apart from that, the T-lymphocyte subsets and changes of IL-2 and β-EP were also detected. Results： After treatment, the aging scores of 223 cases were all substantially reduced, along with an improvement of clinical symptoms, a strengthened cellular immune function, and an increase of total T-lymphocyte count. In addition, the CD4＋/CD8＋ ratio was restored normal, the synthesis or secretion of IL-2 was increased and the β-EP （as the neurotransmitter to modulate immune function） was substantially improved. Conclusion： The aging process is closely associated with the immune function. Moxibustion can modulate abnormal immune function and stabilize homeostasis and thus delay the aging process.展开更多
文摘The effects of opioid peptides on iminune responses were investigated. It was found that β-endorphin (β-END) can depress proliferative responses to PHA in rat splenocytes but enhance those in mice, and it could also inhibit the plaque-forming cell (PFC) response to sheep red blood cells when mouse splenocytes immunized in vivo were cultured in vitro with the peptide. The peptide antagonist naloxone was able to reverse β-END suppression of the PFC response. The data indicate that β-END suppresses antibody production or secretion via a specific opioidreceptor-mediated mechanism.
文摘Objective： To investigate the clinical efficacy and immunological mechanism of herbal cake-partitioned moxibustion for aging process. Method： The herbal cake-partitioned moxibustion was adopted for 223 cases to observe the aging scores before and after the treatment. Apart from that, the T-lymphocyte subsets and changes of IL-2 and β-EP were also detected. Results： After treatment, the aging scores of 223 cases were all substantially reduced, along with an improvement of clinical symptoms, a strengthened cellular immune function, and an increase of total T-lymphocyte count. In addition, the CD4＋/CD8＋ ratio was restored normal, the synthesis or secretion of IL-2 was increased and the β-EP （as the neurotransmitter to modulate immune function） was substantially improved. Conclusion： The aging process is closely associated with the immune function. Moxibustion can modulate abnormal immune function and stabilize homeostasis and thus delay the aging process.
