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老年性心力衰竭96例临床分析 被引量:5
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作者 熊晨晖 《实用诊断与治疗杂志》 2007年第8期625-626,共2页
目的:探讨老年性心力衰竭的临床特点及治疗对策。方法:对符合Framinhan诊断标准的老年性心力衰竭患者96例进行临床症状、体征特点观察,应用血管紧张素酶抑制剂、β阻滞剂、利尿剂为基础药物加其它综合治疗,观察疗效。结果:治疗后心力衰... 目的:探讨老年性心力衰竭的临床特点及治疗对策。方法:对符合Framinhan诊断标准的老年性心力衰竭患者96例进行临床症状、体征特点观察,应用血管紧张素酶抑制剂、β阻滞剂、利尿剂为基础药物加其它综合治疗,观察疗效。结果:治疗后心力衰竭程度显著改善。结论:心力衰竭是老年人主要死亡原因之一,发病率高,诱发因素以呼吸道感染最常见,临床症状不典型者多。 展开更多
关键词 心力衰竭 血管紧张素酶抑 β阻滞制 利尿剂
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RE-EVALUATION OF THE MECHANISM AND TREATMENT OF ANGINA DECUBITUS 被引量:1
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作者 陈纪林 陈在嘉 +5 位作者 徐义枢 高润霖 寇文蓉 姚康宝 于全俊 陶寿琪 《Chinese Medical Sciences Journal》 CAS CSCD 1996年第1期8-12,共5页
patients with angina decubitus (AD) were studied during hospitalization. These patients were found to have severe coronary artery obstructive lesions and an increase of myocardial oxygen consumption (MOC) before the o... patients with angina decubitus (AD) were studied during hospitalization. These patients were found to have severe coronary artery obstructive lesions and an increase of myocardial oxygen consumption (MOC) before the onset to AD, indicating that AD belongs to the category of effort angina.18 patients were investigated by continuous hemodynamic monitoring. Three patients had significant increase in pulmonary artery diastolic pressure (PADP) before the onset. In the other 15 patients. PADP increased slightly in 12 and remained unchanged in 3 cases before the onset. Left ventriculography showed ejection fraction (EF)>45% in 25 of the 27 patients. These results indicate that left ventricular (LV) systolic dysfunction is not a major factor in the Pathogenesis of AD. The patients with LVEDP>12 mmHg constituted 60% of 25 patients with EF>45%, suggesting that these patients had ohvious LV diastolic dysfunction, which may be the major factor in the pathogenesis of AD.According to the results of our treatment, beta blockers may be used as the major form of tteatment in the patients with AD. 展开更多
关键词 angina decubitus LV diastolic dysfunction beta blockers
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Inappropriate use of digoxin in patients presenting with digoxin toxicity 被引量:2
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作者 Mustafa Adem Tatlisu Kazim Serhan Ozcan +3 位作者 Baris Gungor Ahmet Zengin Mehmet Baran Karatas Zekeriya Nurkalem 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2015年第2期143-146,共4页
Background Digoxin remains widely used today despite its narrow therapeutic index and toxicity. The objective of this study was to investigate the percentage of inappropriate use of digoxin and long-term outcomes of e... Background Digoxin remains widely used today despite its narrow therapeutic index and toxicity. The objective of this study was to investigate the percentage of inappropriate use of digoxin and long-term outcomes of elderly patients hospitalized for digoxin toxicity. Methods The study included 99 consecutive patients hospitalized for digoxin toxicity. The other study criteria for the inappropriate use of digoxin was regarded if participants having depressed left ventricular systolic function (ejection fraction 〈 45%) who were not on optimal medical therapy including beta-blocker and angiotensin-converting-enzyme inhibitor therapy or if participants having permanent AF who were not on optimal beta-blocker therapy. Results Appropriate digoxin usage was confirmed in 33 of patients in spite of its narrow therapeutic index. A total of 16 of 99 patients died, with a mean follow-up time of 22.1 ± 10.3 months. Conclusions Contrary to popular belief, the rate of inappropriate digoxin usage remains high. On account of its narrow therapeutic index and toxicity, digoxin should be used more carefully according to the current evidence and guidelines. 展开更多
关键词 DIGOXIN Ejection fraction INDICATIONS TOXICITY
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