The title compound 2-[(4-methoxy-6-methylthio-2-pyrimidinyl)aminocarbonyl- aminosulfonyl]benzoic acid methyl ester (C15H16N4O6S2, Mr = 412.44) was obtained by the reaction of (4-methoxy-6-methylthio-2-pyrimidinyl)amin...The title compound 2-[(4-methoxy-6-methylthio-2-pyrimidinyl)aminocarbonyl- aminosulfonyl]benzoic acid methyl ester (C15H16N4O6S2, Mr = 412.44) was obtained by the reaction of (4-methoxy-6-methylthio-2-pyrimidinyl)amine with 2-methoxylcarbonylbenzene-sulfonylisocya- nate. The crystal is of monoclinic, space group P21/c with a =11.169(3), b = 9.508(3), c = 17.690(5) ? b = 91.593(5), Z = 4, V = 1877.9(10) 3, Dc = 1.459 g/cm3, F(000) = 856, m(MoKa) = 0.324 mm-1, R = 0.0690 and wR = 0.1368 for 3301 observed reflections (I > 2s(I)). The N(1)H…N(3) and N(2)H…O(4) hydrogen bonds can be observed. In the molecule the phenyl plane(I), pyrimi- din-2-yl-urea bridge plane(Ⅱ) and ester plane(Ⅲ) form three conjugated systems.展开更多
Self-assembled structures of 3,4,5-tris-dodecy- loxy benzoic acid methyl ester (E12), 3,4,5-tris-tetradecy- loxy-benzoic acid methyl ester (E14) and their mixture (E12/E14) have been studied on HOPG by scanning tunnel...Self-assembled structures of 3,4,5-tris-dodecy- loxy benzoic acid methyl ester (E12), 3,4,5-tris-tetradecy- loxy-benzoic acid methyl ester (E14) and their mixture (E12/E14) have been studied on HOPG by scanning tunnel- ing microscopy (STM). Dimer-like patterns induced by di- pole-dipole interaction are observed in E12 and E14 monolayers. The molecules form close-packed rows and in- terdigitate with the alkyl chains in adjacent molecules. The structural differences are proposed to be from the different length of substituted alkyl chains. Owing to similar adsorp- tion energy, phase separation is observed in the E12 and E14 mixed adlayer with different domains.展开更多
Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been conf...Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection.展开更多
基金The project was supported by the National Natural Science Foundation of China (20372021) and Natural Science Foundation of Hunan Province (03JJY3018)
文摘The title compound 2-[(4-methoxy-6-methylthio-2-pyrimidinyl)aminocarbonyl- aminosulfonyl]benzoic acid methyl ester (C15H16N4O6S2, Mr = 412.44) was obtained by the reaction of (4-methoxy-6-methylthio-2-pyrimidinyl)amine with 2-methoxylcarbonylbenzene-sulfonylisocya- nate. The crystal is of monoclinic, space group P21/c with a =11.169(3), b = 9.508(3), c = 17.690(5) ? b = 91.593(5), Z = 4, V = 1877.9(10) 3, Dc = 1.459 g/cm3, F(000) = 856, m(MoKa) = 0.324 mm-1, R = 0.0690 and wR = 0.1368 for 3301 observed reflections (I > 2s(I)). The N(1)H…N(3) and N(2)H…O(4) hydrogen bonds can be observed. In the molecule the phenyl plane(I), pyrimi- din-2-yl-urea bridge plane(Ⅱ) and ester plane(Ⅲ) form three conjugated systems.
文摘Self-assembled structures of 3,4,5-tris-dodecy- loxy benzoic acid methyl ester (E12), 3,4,5-tris-tetradecy- loxy-benzoic acid methyl ester (E14) and their mixture (E12/E14) have been studied on HOPG by scanning tunnel- ing microscopy (STM). Dimer-like patterns induced by di- pole-dipole interaction are observed in E12 and E14 monolayers. The molecules form close-packed rows and in- terdigitate with the alkyl chains in adjacent molecules. The structural differences are proposed to be from the different length of substituted alkyl chains. Owing to similar adsorp- tion energy, phase separation is observed in the E12 and E14 mixed adlayer with different domains.
文摘Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection.
