Inclusion Behavior of Dimer β-CyclodextrinBridged with Aspartic Acid Derivative

The (β-cyclodextrin (CD) dimer bridged with aspartic acid (ASP) derivative, FITC-ASP(NH-(-CD)2 (Host, FITC=fluorescein-4-isothiocyanate), was synthesized. Fluorescence polarization study showed that the novel host formed an inclusion compound, [FITC-ASP(NH-(-CD)2]ATA, for which Kd was determined to be 5.0×10-6 mol/L by Beacon 2000 Analyzer, when ATA (Guest) = Adm-Trp-Arg-Arg-NH2 (Adm = 1-adamantanecarboxylic acid, Trp = tryptophan, Arg = arginine), where Kd is the dissociation constant in aqueous solution at 298 K.

Study on the inclusion compound of β-cyclodextrin with (η5-cyclopentadienyl)tricarbonylmanganese(0)

The supramolecular inclusion compound of β-cyclodextrin (β-CD, host) with (η5-cyclopentadienyl)tricarbonylmanganese [MnCp(CO)3, guest] was obtained in a crystalline state. The host-guest compound is thermally stable and do not liberate the guest on heating at 100$ in vacuum. It was characteried by elemental analysis,1H NMR, differential scanning thermal (DSC) analysis and TLC. Continueous variation plot by NMR method shows that β-CD formed 1:1 inclusion compound with MnCp(CO)3. On the basis of 1H NMR spectra and the model building with Corey Pauling Koltum (CPK) models, the most probable inclusion mode is proposed.

Interaction of β-Cyclodextrin Catalyst with p-Chlorobenzonitrile for the Synthesis of 5-Substituted 1H-tetrazoles in n,n-Dimethylformamide：a DFT Study

The synthesis of 5-substituted 1H-tetrazoles in n,n-dimethylformamide（DMF） with b-cyclodextrin（β-CD） as catalyst can get an excellent yield in short reaction time.The interaction of β-CD with p-chlorobenzonitrile plays an important role in this process.This paper studies the complex of β-CD with p-chlorobenzonitrile using density functional theory（DFT） method.The minimum energy structure is investigated in water,DMF and DMSO.Hydrogen bonds are researched on the basis of natural bonding orbital（NBO） analysis.The relative position between p-chlorobenzonitrile and β-CD in DMF is confirmed by 1H nuclear magnetic resonance（1H NMR）.The data from 13 C and 15 N spectra indicate that more positive charges focus on the carbon atom of cyanogroup（C11） and more negative charges concentrate on the nitrogen atom of cyanogroup（N12） upon complexation.The results from frontier molecular orbitals and Mulliken charge reveal that β-CD catalyst improves the reactivity and electrophilicity of p-chlorobenzonitrile.Meanwhile,the functional group of p-chlorobenzonitrile is easier to be attacked by azide ions in the presence of β-CD as catalyst.

A new approach to the synthesis of N-monosubstituted aniline and its derivatives viaβ-cyclodextrin host-guest complexes

A novel method for the synthesis of N-monosubstituted aniline and its derivatives via β-cyclodextrin （CD） host-guest complexes has been presented. The mild reaction gives the title compounds with high selectivity in good yields of 90-98%.

Preparation and Characterization of Holmium-Beta-Cyclodextrin Complex

The purpose of this study was to prepare and characterize of holmium-beta-cyclodextrin complex (Ho-β-CD) in order to increase the solubility and stability of Holmium. To achieve this goal, Ho-β-CD complex was prepared by evaporation method of holmium and beta cyclodextrin solutions in a proportion (1:1) and (1:3), respectively. Infrared (IR) and Raman spectroscopy, X-Ray Diffraction were performed to identify the complex. Morphology of the Ho, β-CD, and Ho-β-CD were studied using Scanning Electron Microscopy (SEM).

NMR and IR Investigations of Ternary Inclusion Complexes among β-Cyclodextrin, Rare Earth Metal Ions, and Naphthalenediamines

Ternary inclusion complexes β-cyclodextrin （β-CD）, rare earth metal ions （YbC13, YC13）, and 1,8-naphthalene- diamine/ 1,5-naphthalenediamine are synthesized in basic aqueous media, which are characterized via IH NMR and IR spectroscopy. The stoichiometric proportion of β-CD ： YbC13 ： 1, 5-naphthalenedia- mine is 2：1：2, that of β-CD：YCI3 ： 1,8-naphthalenediamine is 2：1：1, and that of β-CD：YbC13 ： 1,8-naphthalenediamine is 2 ： 1 ： 1. The IR spectroscopy of the ternary inclusion complexes in the range of 935-1 000 cm 1 reveals the existence of the coordinate bond M---O or M---N. The possible conformations of the ternary inclusion complexes are depicted.