期刊文献+
共找到875篇文章
< 1 2 44 >
每页显示 20 50 100
ON THE EXACT HAUSDORFF MEASURE OF A CLASS OF SELF-SIMILAR SETS SATISFYING OPEN SET CONDITION 被引量:2
1
作者 Shaoyuan Xu Weiyi Su Zuoling Zhou 《Analysis in Theory and Applications》 2008年第1期93-100,共8页
In this paper, we provide a new effective method for computing the exact value of Hausdorff measures of a class of self-similar sets satisfying the open set condition (OSC). As applications, we discuss a self-simila... In this paper, we provide a new effective method for computing the exact value of Hausdorff measures of a class of self-similar sets satisfying the open set condition (OSC). As applications, we discuss a self-similar Cantor set satisfying OSC and give a simple method for computing its exact Hausdorff measure. 展开更多
关键词 self-similar set Hausdorff measure and Hausdorff dimension open set condition
下载PDF
γ-(α,β)-Open Sets and γ-(α,β)-Ti Spaces 被引量:1
2
作者 WU Yao-qiang 《Chinese Quarterly Journal of Mathematics》 2018年第3期324-330,共7页
We introduce the concept of γ-(α, β)-open sets and the concepts of γ-(α, β)-T_i spaces(i = 0, 1, 2, 3, 4) based on the concept of(α, β)-open sets. We obtain some properties of γ-(α, β)-Tispaces. Furthermore... We introduce the concept of γ-(α, β)-open sets and the concepts of γ-(α, β)-T_i spaces(i = 0, 1, 2, 3, 4) based on the concept of(α, β)-open sets. We obtain some properties of γ-(α, β)-Tispaces. Furthermore, we study their essential characterization in topological space. 展开更多
关键词 γ-open sets β)-open sets γ- β)-open sets γ- β)-Tispaces
下载PDF
On <i>M</i>-Asymmetric Semi-Open Sets and Semicontinuous Multifunctions in Bitopological Spaces 被引量:2
3
作者 Levy K. Matindih Edwin Moyo 《Advances in Pure Mathematics》 2021年第4期218-236,共19页
The purpose of this paper is to introduce the notions of <em>m</em>-asymmetric semiopen sets and <em>M</em>-asymmetric semicontinuous multifunctions defined between asymmetric sets satisfying c... The purpose of this paper is to introduce the notions of <em>m</em>-asymmetric semiopen sets and <em>M</em>-asymmetric semicontinuous multifunctions defined between asymmetric sets satisfying certain minimal conditions in the framework of bitopological spaces. Some new characterizations of <em>m</em>-asymmetric semiopen sets and <em>M</em>-asymmetric semicontinuous multifunctions will be investigated and several fundamental properties will be obtained. 展开更多
关键词 m-Spaces m-Semiasymmetric open and Closed sets Upper and Lower M-Asymmetric Semicontinuous Multifunction
下载PDF
基于YOLO-OpenMax的水声通信信号开集识别方法
4
作者 李杰 李勇斌 +2 位作者 郑娄 王彬 黄焱 《信息工程大学学报》 2024年第3期258-264,271,共8页
水声通信信号调制方式随着技术进步从典型的传统调制方式发展为水声通信机厂商私有开发的新型调制方式,这使得现有的水声通信信号闭集调制识别技术实用性受到制约,但现阶段鲜有研究基于深度学习的水声通信信号调制方式的开集识别方法。... 水声通信信号调制方式随着技术进步从典型的传统调制方式发展为水声通信机厂商私有开发的新型调制方式,这使得现有的水声通信信号闭集调制识别技术实用性受到制约,但现阶段鲜有研究基于深度学习的水声通信信号调制方式的开集识别方法。针对此现状,提出一种基于YOLO图像检测识别网络和OpenMax模型的开集识别方法。利用YOLOv5网络的输出特点,将传统OpenMax模型的处理方法进行改进,提出一种两步测试方法,实现了在多径信道下的水声通信信号的开集识别。仿真实验表明:在归一化系数为0.5,信噪比等于10 dB条件下的归一化开集识别准确率达到90%以上,实测数据同样验证了本文方法的有效性。 展开更多
关键词 水声通信 调制方式识别 开集识别 两步测试流程
下载PDF
SETD5介导AKT1磷酸化调控结肠癌细胞的迁移和5-FU敏感性
5
作者 黄开禹 史建国 程勇 《中国肿瘤生物治疗杂志》 CAS CSCD 北大核心 2024年第6期586-591,共6页
目的:探讨含SET结构域蛋白5(SETD5)对结肠癌细胞增殖、迁移和对5-氟尿嘧啶(5-FU)药物敏感性的影响及机制。方法:常规培养结肠癌细胞,用Lipofectamine 2000将siSETD5-NC、si-SETD5-1~3质粒转染至HT-29细胞中,将其分为对照组(未处理)、si-... 目的:探讨含SET结构域蛋白5(SETD5)对结肠癌细胞增殖、迁移和对5-氟尿嘧啶(5-FU)药物敏感性的影响及机制。方法:常规培养结肠癌细胞,用Lipofectamine 2000将siSETD5-NC、si-SETD5-1~3质粒转染至HT-29细胞中,将其分为对照组(未处理)、si-SETD5-NC组、si-SETD5组和si-SETD5+SC79组,si-SETD5+SC79组HT-29细胞转染质粒的同时用10µmol/L SC79处理。qPCR法检测NCM460、HT-29和LoVo细胞中SETD5 mRNA表达,流式细胞术、细胞划痕法、WB法和CCK-8法分别检测各组HT-29细胞的凋亡情况、迁移能力、相关蛋白的表达,以及对5-FU的敏感性。结果:SETD5 mRNA在HT-29、LoVo细胞中均呈高表达(均P<0.01)。在HT-29细胞中成功地敲减了SETD5 mRNA(P<0.01)。敲减SETD5 mRNA可明显抑制HT-29细胞的增殖活性(P<0.01)、迁移能力(P<0.01)、相关蛋白(SETD5、p-PI3K、p-AKT1、p-mTOR蛋白)的表达(均P<0.01)、促进细胞凋亡(P<0.01),且提高其对5-FU的敏感性(P<0.01),这些作用均可被AKT激活剂SC79部分阻挡(P<0.05或P<0.01)。结论:SETD5在HT-29、LoVo细胞中高表达,SETD5通过PI3K/AKT1通路促进结肠癌HT-29细胞的增殖、迁移,且降低其对5-FU的敏感性,SETD5是结肠癌临床诊断、治疗的潜在靶点。 展开更多
关键词 结肠癌 含有set结构域蛋白5 蛋白激酶B磷酸化 增殖 迁移 5-氟尿嘧啶 耐药
下载PDF
S-rough sets and knowledge separation 被引量:104
6
作者 Shi Kaiquan 1,21. School of Mathematics and System Sciences, Liaocheng University, Liaocheng 252059, P. R. China 2. School of Mathematics and System Sciences, Shandong University, Jinan 250100, P. R. China 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2005年第2期403-410,共8页
The conceptions of the knowledge screen generated by S-rough sets are given: f- screen and - screen , and then puts forward - filter theorem, - filter theorem of knowledge. At last, the applications of knowledge separ... The conceptions of the knowledge screen generated by S-rough sets are given: f- screen and - screen , and then puts forward - filter theorem, - filter theorem of knowledge. At last, the applications of knowledge separation are given according to - screen and - screen. 展开更多
关键词 S- rough sets f- screen - screen f-filter theorem - filter theorem knowledge separation.
下载PDF
Spatial Distribution Feature Extraction Network for Open Set Recognition of Electromagnetic Signal
7
作者 Hui Zhang Huaji Zhou +1 位作者 Li Wang Feng Zhou 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期279-296,共18页
This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distri... This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distribution feature extraction layer in SDFEN replaces convolutional output neural networks with the spatial distribution features that focus more on inter-sample information by incorporating class center vectors.The designed hybrid loss function considers both intra-class distance and inter-class distance,thereby enhancing the similarity among samples of the same class and increasing the dissimilarity between samples of different classes during training.Consequently,this method allows unknown classes to occupy a larger space in the feature space.This reduces the possibility of overlap with known class samples and makes the boundaries between known and unknown samples more distinct.Additionally,the feature comparator threshold can be used to reject unknown samples.For signal open set recognition,seven methods,including the proposed method,are applied to two kinds of electromagnetic signal data:modulation signal and real-world emitter.The experimental results demonstrate that the proposed method outperforms the other six methods overall in a simulated open environment.Specifically,compared to the state-of-the-art Openmax method,the novel method achieves up to 8.87%and 5.25%higher micro-F-measures,respectively. 展开更多
关键词 Electromagnetic signal recognition deep learning feature extraction open set recognition
下载PDF
miR-127-3p靶向调节SETD8对胃癌细胞增殖、迁移和侵袭的影响
8
作者 冯丽萍 张辉洁 +1 位作者 欧雯婷 余盈 《中国老年学杂志》 CAS 北大核心 2024年第4期957-962,共6页
目的探讨微小RNA(miR)-127-3p对胃癌细胞增殖、迁移及侵袭的影响及其作用机制。方法采用qRT-聚合酶链反应(PCR)检测150例胃癌患者胃癌组织、癌旁组织及人胃上皮细胞GES1、人胃癌细胞SGC7901、AGS、MKN-45、MGC-803中miR-127-3p表达水平... 目的探讨微小RNA(miR)-127-3p对胃癌细胞增殖、迁移及侵袭的影响及其作用机制。方法采用qRT-聚合酶链反应(PCR)检测150例胃癌患者胃癌组织、癌旁组织及人胃上皮细胞GES1、人胃癌细胞SGC7901、AGS、MKN-45、MGC-803中miR-127-3p表达水平。双荧光素酶报告基因检测miR-127-3p与含SET结构域赖氨酸甲基转移酶(SETD)8的靶向调控关系。将SGC7901细胞分为对照(Control)组、miR-127-3p模拟物(miR-127-3p mimics)组及miR-NC组、沉默SETD8表达(si-SETD8)组、si-NC组、miR-127-3p mimics+SETD8过表达(miR-127-3p mimics+SETD8)组及空载质粒(miR-127-3p mimics+pcDNA)组。噻唑蓝(MTT)法、划痕愈合实验、Transwell小室实验分别检测SGC7901细胞增殖、迁移与侵袭;Western印迹检测SGC7901细胞SETD8、基质金属蛋白酶(MMP)-2、MMP-9蛋白表达;裸鼠成瘤实验检测过表达miR-127-3p对裸鼠胃癌移植瘤生长的影响。结果miR-127-3p在胃癌组织与细胞中较癌旁组织和正常细胞显著下调(P<0.05),SETD8 mRNA在胃癌组织中较癌旁组织显著上调(P<0.05);胃癌组织中miR-127-3p、SETD8 mRNA表达水平呈负相关(r=-0.553,P<0.05);双荧光素酶实验证实miR-127-3p与SETD8存在靶向调控关系(P<0.05);过表达miR-127-3p或抑制SETD8表达显著抑制SGC7901细胞增殖、迁移与侵袭(P<0.05);过表达SETD8可部分逆转过表达miR-127-3p对SGC7901细胞增殖、迁移与侵袭的抑制作用(P<0.05);裸鼠成瘤实验表明过表达miR-127-3p可显著抑制胃癌移植瘤生长(P<0.05)。结论miR-127-3p在胃癌组织与细胞中表达下调,过表达miR-127-3p可靶向抑制SETD8表达而抑制胃癌肿瘤生长。 展开更多
关键词 微小RNA-127-3p set结构域赖氨酸甲基转移酶8 胃癌细胞 增殖 迁移 侵袭
下载PDF
miR-184-3p促进舌鳞状细胞癌生长的作用机制研究
9
作者 赖河青 陈雅婷 +1 位作者 潘连芬 徐国超 《浙江医学》 2025年第1期21-26,31,I0004-I0006,共10页
目的探讨miR-184-3p通过抑制SET结构域蛋白2(SETD2)调节N-Myc原癌基因蛋白(MYCN)启动子的组蛋白H3第36位赖氨酸三甲基化(H3K36me3)修饰促进舌鳞状细胞癌(TSCC)发生、发展的机制。方法培养正常口腔上皮细胞系HOEC、TSCC细胞系(CAL27、SC... 目的探讨miR-184-3p通过抑制SET结构域蛋白2(SETD2)调节N-Myc原癌基因蛋白(MYCN)启动子的组蛋白H3第36位赖氨酸三甲基化(H3K36me3)修饰促进舌鳞状细胞癌(TSCC)发生、发展的机制。方法培养正常口腔上皮细胞系HOEC、TSCC细胞系(CAL27、SCC-4和SCC-9)。采用实时荧光定量聚合酶链反应法检测细胞miR-184-3p表达水平,细胞计数试剂盒8法检测细胞增殖能力,流式细胞术检测细胞凋亡率,克隆形成实验检测细胞克隆形成能力,划痕愈合实验检测细胞迁移能力,Transwell实验检测细胞侵袭能力,蛋白质印迹法检测SETD2、MYCN、H3K36me3表达水平。结果与HOEC细胞相比,TSCC细胞miR-184-3p表达上调,SETD2表达下调,MYCN表达上调,TSCC细胞增殖、迁移和侵袭能力增强,差异均有统计学意义(均P<0.05)。干扰CAL27、SCC-4细胞miR-184-3p表达后,H3K36me3表达上调,MYCN表达下调,细胞增殖、迁移和侵袭能力减弱;干扰CAL27细胞MYCN表达后,MYCN表达下调,细胞增殖、迁移和侵袭能力减弱,差异均有统计学意义(均P<0.05),而H3K36me3表达不变;干扰CAL27细胞MYCN表达,同时过表达miR-184-3p后,MYCN表达上调,细胞增殖、迁移和侵袭能力增强,H3K36me3表达下调,差异均有统计学意义(均P<0.05)。CAL27细胞过表达SETD2后,MYCN表达下调,H3K36me3表达上调,差异均有统计学意义(均P<0.05)。CAL27细胞过表达SETD2,同时过表达MYCN后,H3K36me3表达不变。结论在TSCC中高表达的miR-184-3p通过抑制SETD2调节MYCN启动子H3K36me3修饰促进TSCC细胞增殖、迁移和侵袭。 展开更多
关键词 miR-184-3p 舌鳞状细胞癌 N-Myc原癌基因蛋白 组蛋白H3第36位赖氨酸三甲基化 set结构域蛋白2
下载PDF
Exclusive Fibula Osteosynthesis for Treating Open Fractures Gustillo I-III B of the Distal Half of the Leg Bones in a Resources-Limited Setting
10
作者 Georges Kuyigwa Toha Paul Munguakonkwa Budema +2 位作者 Ona Longombe Ahuka Akinja Bitum Uwonda Jean Marie Vianney Kabangu Tshimbila 《Open Journal of Orthopedics》 2023年第3期108-121,共22页
Introduction: Management of open leg bones fractures is a challenging health issue for the surgeon, particularly true in resource-limited settings. In this study, we evaluate exclusive fibular osteosynthesis in the tr... Introduction: Management of open leg bones fractures is a challenging health issue for the surgeon, particularly true in resource-limited settings. In this study, we evaluate exclusive fibular osteosynthesis in the treatment of open fractures of the distal half of the leg bones as a therapeutic option in our context. Methods: This is a prospective, experimental, multicenter study of 30 open fractures of the distal half of the leg bones treated with exclusive fibula osteosynthesis, conducted in 3 hospitals in the DRC from January 1, 2013 to September 30, 2016. Results: The age range of 20 to 40 years grouped 22 (73.4%) patients, the sex ratio was 1:1 and the unemployed were the most involved with 16 (53.3%) cases. The Gustilo II, I, III B and III A types represented 40%, 33.3%, 20% and 6.7%, respectively. The fractures were located in the distal third in 12 (40%) cases, in the middle third in 11 (36.7%) cases, and in both malleoli in 7 cases (23.3%). Osteosynthesis of the fibula by screw plate was applied in 22 (73.3%) patients and pinning in 8 (26.7%). Satisfactory reduction of the tibial fracture site was achieved in 29 (96.7%) cases and 100% bone healing was achieved within an average of 10 weeks. Four (13.3%) loss of alignment, 1 (3.3%) infection, 1 (3.3%) skin necrosis and 2 (6.7%) ankle stiffness complicated our fractures. Conclusion: Exclusive osteosynthesis of the fibula as a common technique for fractures of the distal half of the leg bones allowed us to reduce, immobilize and consolidate the tibial fracture in the required time and to preserve the mobility of the ankle. 展开更多
关键词 Fibular Exclusive Osteosynthesis open Tibial Fractures Resources Limited settings Tibial Fracture Consolidation
下载PDF
Weak Form of Fuzzy Open Sets and Their Related Continuity
11
作者 N. Gowrisankar N. Rajesh 《模糊系统与数学》 CSCD 北大核心 2010年第3期86-91,共6页
The aim of this paper is to give a new class of fuzzy open sets called fuzzy pre-γ-open sets in fuzzy topological spaces. Also,a new type of fuzzy continuous functions called,fuzzy pre-γ-continuous functions is intr... The aim of this paper is to give a new class of fuzzy open sets called fuzzy pre-γ-open sets in fuzzy topological spaces. Also,a new type of fuzzy continuous functions called,fuzzy pre-γ-continuous functions is introduced and studied. 展开更多
关键词 模糊理论 空间理论 计算方法 数学理论
下载PDF
SN0144i-XX小井眼测井仪器套捞一体打捞技术研究及应用
12
作者 史配铭 李刚 刘振 《石油工业技术监督》 2025年第2期1-6,共6页
SN0144i-XX井是一口目的层为马家沟组碳酸盐岩储层小井眼井,完钻井深3805 m,152.4 mm裸眼段长3040 m,最大井斜24°,最大狗腿度4.05°,钻井液密度1.16 g/cm^(3)。井口起仪器过程中Φ57 mm测井仪器串落井,因井眼、仪器尺寸较小,... SN0144i-XX井是一口目的层为马家沟组碳酸盐岩储层小井眼井,完钻井深3805 m,152.4 mm裸眼段长3040 m,最大井斜24°,最大狗腿度4.05°,钻井液密度1.16 g/cm^(3)。井口起仪器过程中Φ57 mm测井仪器串落井,因井眼、仪器尺寸较小,仪器串结构复杂,仪器串抗拉抗压参数受限,落井仪器状态不明等问题,采用常规打捞技术已不能满足Φ152.4 mm小井眼中Φ57 mm测井仪器串的打捞要求,为此,通过分析测井仪器结构,每趟打捞出井仪器结构及落鱼在井筒内的相对位置及状态,开展套捞一体式专用打捞工具的设计制作、打捞方案的制定等研究,采用磁定位仪器确定鱼头技术,精准确定鱼头位置,提高仪器打捞成功率,设计制作了Φ146 mm大引鞋+Φ110 mm卡瓦打捞筒、Φ143 mm套铣头栽钢丝+内嵌式Φ110 m卡瓦打捞筒、Φ143 mm套铣管开窗+内嵌式Φ110 mm卡瓦打捞筒等套捞一体式打捞工具,进行26次的连续打捞作业,耗时45 d成功捞出落井仪器串19 m。阐述了小井眼裸眼井测井仪器落井后开展的套捞一体式非常规打捞工具设计加工、打捞方案编制及关键打捞措施,为今后类似测井仪器落井非常规打捞作业提供了一定的技术参考。 展开更多
关键词 小井眼 裸眼井 测井仪器 套捞一体式打捞工具 打捞技术
下载PDF
LEVEL SET输运方程的求解方法及其对气-液两相流运动界面数值模拟的影响 被引量:10
13
作者 李会雄 邓晟 +2 位作者 赵建福 陈听宽 王飞 《核动力工程》 EI CAS CSCD 北大核心 2005年第3期242-248,267,共8页
用数值模拟方法来研究气-液两相流动与传热现象是当今多相流领域的一个热门课题。由于两相流固有的复杂性,气-液两相流界面迁移现象的数值模拟一直是两相流研究中的一大难点。本文介绍了捕捉气-液两相流相界面运动的水平集方法(LevelSet... 用数值模拟方法来研究气-液两相流动与传热现象是当今多相流领域的一个热门课题。由于两相流固有的复杂性,气-液两相流界面迁移现象的数值模拟一直是两相流研究中的一大难点。本文介绍了捕捉气-液两相流相界面运动的水平集方法(LevelSet)及其研究进展,介绍了求解LevelSet输运方程的3种方法,即一般差分格式、Superbee-TVD格式和Runge-Kutta法-5阶WENO组合格式。结合主流场的求解,分别用这3种方法对4种典型相界面在5种流场中的迁移特性进行了模拟计算,并对计算结果进行了比较和分析。结果表明,Runge-Kutta法-5阶WENO组合格式求解LevelSet输运方程的效果最好,在以后的计算中将主要采用这种组合格式来进行气-液相界面输运方程的求解。 展开更多
关键词 运动界面 LEVEL set方法 -液两相流 5阶WENO格式 Superbee-TVD格式
下载PDF
高磷通过SET8-shRNA调控AKT/Caspase-3通路促进血管平滑肌细胞凋亡 被引量:7
14
作者 刘兰 张东雪 +3 位作者 朱荣芳 梁向楠 李晖 张胜雷 《山西医科大学学报》 CAS 2021年第10期1312-1318,共7页
目的探讨高磷通过SET8-shRNA调控AKT/Caspase-3通路促进大鼠血管平滑肌细胞(vascular smooth muscle cells,VSMCs)发生钙化的机制。方法将血管平滑肌细胞随机分为两组:正常组和高磷组(10 mmol/Lβ-甘油磷酸)。采用茜素红染色及钙含量检... 目的探讨高磷通过SET8-shRNA调控AKT/Caspase-3通路促进大鼠血管平滑肌细胞(vascular smooth muscle cells,VSMCs)发生钙化的机制。方法将血管平滑肌细胞随机分为两组:正常组和高磷组(10 mmol/Lβ-甘油磷酸)。采用茜素红染色及钙含量检测血管平滑肌细胞钙化,采用实时荧光定量及Western blot检测SET8、AKT、Caspase-3 mRAN和蛋白表达情况。为验证SET8在细胞钙化中的作用,将大鼠VSMCs分为6组:正常组、空质粒组、SET8低表达组(转染SET8-shRNA质粒)、高磷组(10 mmol/Lβ-甘油磷酸)、空质粒+高磷组(高磷基础上转染SET8过表达的对照质粒)、SET8过表达+高磷组(高磷基础上转染SET8过表达质粒)。检测各组血管平滑肌细胞的钙化、凋亡及AKT、Caspase-3表达情况。为进一步验证AKT在VSMCs钙化中的作用,将血管平滑肌细胞分为3组:AKT抑制剂组(1μl DMSO+AKT抑制剂LY294002)、对照组(1μl DMSO)和正常组,检测AKT、Caspase-3 mRAN和蛋白表达。结果与正常组比较,高磷组细胞钙化结节增多,钙含量增加(P<0.05),STE8和AKT表达降低,Caspase-3表达升高(P<0.05)。与正常组和空质粒组比较,SET8-shRNA组细胞钙化和凋亡增多,AKT表达降低,Caspase-3表达升高(P<0.05);与高磷组和空质粒+高磷组比较,SET8过表达+高磷组细胞钙化和凋亡减少,AKT表达升高,Caspase-3表达降低(P<0.05)。与正常组和对照组比较,AKT抑制剂组AKT表达显著降低,Caspase-3表达显著升高(P<0.05)。结论高磷通过SET8-shRNA抑制AKT活化,进而促进Caspase-3表达,增加VSMCs凋亡,从而影响细胞钙化的发生。 展开更多
关键词 血管平滑肌细胞 set8 AKT Caspase-3 β-甘油磷酸
下载PDF
B7-H3、葡萄糖6-磷酸脱氢酶及SET8蛋白在肾透明细胞癌中的表达及与预后的关系分析 被引量:1
15
作者 程波 黄连饴 张海芳 《癌症进展》 2021年第10期1047-1049,1065,共4页
目的分析B7-H3、葡萄糖6-磷酸脱氢酶(G6PD)及SET8蛋白在肾透明细胞癌中的表达及与预后的关系。方法收集81例肾透明细胞癌患者的肾透明细胞癌组织及正常组织,比较不同组织中B7-H3、G6PD及SET8蛋白阳性表达情况,随访2年分析肾透明细胞癌... 目的分析B7-H3、葡萄糖6-磷酸脱氢酶(G6PD)及SET8蛋白在肾透明细胞癌中的表达及与预后的关系。方法收集81例肾透明细胞癌患者的肾透明细胞癌组织及正常组织,比较不同组织中B7-H3、G6PD及SET8蛋白阳性表达情况,随访2年分析肾透明细胞癌预后的影响因素。结果肾透明细胞癌组织中B7-H3、G6PD及SET8蛋白阳性表达率均明显高于正常组织,差异均有统计学意义(P﹤0.01)。多因素分析结果显示,肿瘤直径≥5 cm、TNM分期为Ⅲ-Ⅳ期、有淋巴结转移、细胞分级为G2-3级、B7-H3阳性、G6PD阳性、SET8阳性均为影响肾透明细胞癌患者预后的独立危险因素(P﹤0.05)。结论B7-H3、G6PD及SET8蛋白在肾透明细胞癌中均高表达,在临床中检测三者表达情况对患者预后评估有重要参考价值。 展开更多
关键词 B7-H3 葡萄糖6-磷酸脱氢酶 set8 肾透明细胞癌 表达 预后
下载PDF
基于SET/MOS混合结构的4-2编码器设计
16
作者 魏榕山 陈锦锋 +1 位作者 陈寿昌 何明华 《南昌大学学报(工科版)》 CAS 2011年第2期190-193,共4页
基于单电子晶体管(SET)的库仑振荡效应、多栅输入特性和相移特性,实现了SET/MOS混合结构的或门逻辑,并利用该或门逻辑实现了4-2编码器。利用HSPICE对所设计电路进行仿真验证,仿真结果表明该电路能够实现4-2编码器的编码功能。与纯CMOS... 基于单电子晶体管(SET)的库仑振荡效应、多栅输入特性和相移特性,实现了SET/MOS混合结构的或门逻辑,并利用该或门逻辑实现了4-2编码器。利用HSPICE对所设计电路进行仿真验证,仿真结果表明该电路能够实现4-2编码器的编码功能。与纯CMOS编码器相比,该SET/MOS混合电路仅由2个PMOS管、2个NMOS管和2个SET构成,具有结构简单、尺寸小、集成度高的优点。 展开更多
关键词 单电子晶体管 set/MOS混合电路 4-2编码器 HSPICE仿真
下载PDF
细胞自身分化抗原-1—SET家族的新成员
17
作者 韩淑华 陈秋惠 迟宝荣 《中国老年学杂志》 CAS CSCD 北大核心 2006年第4期571-573,共3页
关键词 细胞自身分化抗原-1 set家族 转化生长因子Β1
下载PDF
数字政府背景下政府开放数据创新应用提升路径研究--基于31个省域应用数据的模糊集定性比较分析
18
作者 陶志梅 李芯蕊 高先涛 《天津商业大学学报》 2024年第3期58-64,共7页
政府开放数据是典型的创新扩散模型,受到国家政治制度和府际关系的深刻影响,解释政府开放数据创新应用的提升路径需要以府际关系和制度压力规制为逻辑起点,构建开放数据创新扩散模型,应用模糊集定性比较分析对我国31个省域政府开放数据... 政府开放数据是典型的创新扩散模型,受到国家政治制度和府际关系的深刻影响,解释政府开放数据创新应用的提升路径需要以府际关系和制度压力规制为逻辑起点,构建开放数据创新扩散模型,应用模糊集定性比较分析对我国31个省域政府开放数据应用创新扩散规律进行总结。研究发现上级压力规制、公众压力、府际竞争和府际学习因素组合是最典型的政府开放数据应用创新扩散模型,对开放数据创新应用和数据价值实现有更好的促进作用。除此之外,对于经济较发达且对上级财政依赖较小的地区可以通过政策压力、府际竞争和府际学习提升数据开放创新活动;而在经济欠发达且对上级财政依赖较大的地区,上级压力对开放数据应用扩散作用更突出。 展开更多
关键词 政府开放数据 开放数据应用 创新扩散理论 模糊集定性比较分析
下载PDF
Geochemistry of sedimentary rocks from Permian–Triassic boundary sections of Tethys Himalaya: implications for paleo-weathering, provenance, and tectonic setting 被引量:3
19
作者 Akhtar R.Mir V.Balaram +2 位作者 Javid A.Ganai Shamim A.Dar A.Keshav Krishna 《Acta Geochimica》 EI CAS CSCD 2016年第4期428-436,共9页
The geochemical characteristics of two sections—the Permian–Triassic boundary(PTB) Guryul Ravine section, Kashmir Valley, Jammu and Kashmir,India; and the Attargoo section, Spiti Valley, Himachal Pradesh, India—hav... The geochemical characteristics of two sections—the Permian–Triassic boundary(PTB) Guryul Ravine section, Kashmir Valley, Jammu and Kashmir,India; and the Attargoo section, Spiti Valley, Himachal Pradesh, India—have been studied in the context of provenance, paleo-weathering, and plate tectonic setting.These sections represent the siliciclastic sedimentary sequence from the Tethys Himalaya. The PTB siliciclastic sedimentary sequence in these regions primarily consists of sandstones and shales with variable thickness. Present studied sandstones and shales of both sections had chemical index of alteration values between 65 and 74; such values reveal low-to-moderate degree of chemical weathering. The chemical index of weathering in studied samples ranged from 71 to 94, suggesting a minor K-metasomatism effect on these samples. Plagioclase index of alteration in studied sections ranged from 68 to 92, indicating a moderate degree of weathering of plagioclase feldspars. The provenance discriminant function diagram suggests that the detritus involved in the formation of present studied siliciclastic sedimentary rocks fall in quartzose sedimentary and felsic igneous provenances. These sediments were deposited in a passive continental margin plate tectonic setting according to their location on a Si_2 O versus K_2O/Na_2 O tectonic setting diagram. 展开更多
关键词 GEOCHEMISTRY Permian-Triassic boundary - Guryul Ravine Tectonic settings
下载PDF
Process for improving the ladle free- opening rate for high aluminum steel in continuous casting 被引量:3
20
作者 LIU Junzhan ZHOU Tongjun LUO Hui 《Baosteel Technical Research》 CAS 2015年第1期42-45,共4页
Steel 20Mn23AlV is a type of high aluminum steel with a very low ladle free-opening rate. The aluminum composition of 20Mn23AlV ranges from 1.6% to 2.45% ,which is significantly higher than other types of steel. Accor... Steel 20Mn23AlV is a type of high aluminum steel with a very low ladle free-opening rate. The aluminum composition of 20Mn23AlV ranges from 1.6% to 2.45% ,which is significantly higher than other types of steel. According to the real condition of 40 t ladle in steel-making plant of Baosteel Special Steel Company, previous works show that the key factors affecting the ladle free-opening rate of high aluminum steel in continuous casting are:sand material, accessories baking, ladle nozzle cleaning, the process and amount of adding sand, and the rate of argon stirring during refining. Therefore, improving the ladle filler sand quality, baking all of the raw materials, controlling the addition of ladle filler sand, cleaning the ladle nozzle, and optimizing argon stirring during the refining process can resolve the problem of a low ladle free-opening rate of high aluminum steel caused by the long ladle time of liquid steel. 展开更多
关键词 continuous casting high aluminum steel LADLE free - opening rate
下载PDF
上一页 1 2 44 下一页 到第
使用帮助 返回顶部