目的探讨成人接种60μg重组乙型肝炎疫苗(酿酒酵母)的免疫成功率和效果。方法选择我县200名16岁以上已进行乙肝疫苗免疫且没有抗体产生的人群,由深圳康泰生物制品股份有限公司提供60μg重组乙型肝炎疫苗220支,批号20100732-1,一针接种后...目的探讨成人接种60μg重组乙型肝炎疫苗(酿酒酵母)的免疫成功率和效果。方法选择我县200名16岁以上已进行乙肝疫苗免疫且没有抗体产生的人群,由深圳康泰生物制品股份有限公司提供60μg重组乙型肝炎疫苗220支,批号20100732-1,一针接种后1个月采血,进行血清免疫学检测。结果接种人群均未出现异常反应。接种一针后1个月,阳转率达98%,抗-HBs几何平均滴度(GMT)为150.88 m IU/m L。结论60μg重组乙型肝炎疫苗安全性良好,免疫成功率高,可用于成人乙肝疫苗加强免疫。展开更多
A novel second-order nonlinear optical chromophore (DCDHF-2-V) was synthesized from 3-Hydroxy-3-methyl-2-butanae, propanedinitrile and 4-diethylaminobenzaldehyde by aldol condensation reaction. Molecular structural ch...A novel second-order nonlinear optical chromophore (DCDHF-2-V) was synthesized from 3-Hydroxy-3-methyl-2-butanae, propanedinitrile and 4-diethylaminobenzaldehyde by aldol condensation reaction. Molecular structural characterization was investigated by elemental analysis, FTIR, and 1H-NMR spectra. The melting point obtained from DSC thermogram was almost 251 ℃, and the compound shows a thermal stability up to 270 ℃. Second-order NLO properties of the chro- mophore were measured by solvatochromic method. From the quantum-mechanical two-level model, it can be obtained that the value of DCDHF-2-V is 6520 × 10-48 esu at the wavelength of 1064 nm.展开更多
目的探讨重组乙型肝炎(乙肝)疫苗(酵母)[Hepatitis B Vaccine Made by Recombinant DNA Techniques inYeast,HepB(Yeast)]10μg成人免疫失败的因素,为制定成人HepB接种方案提供依据。方法随机选取≥18岁易感人群,按0、1、6个月免疫程序...目的探讨重组乙型肝炎(乙肝)疫苗(酵母)[Hepatitis B Vaccine Made by Recombinant DNA Techniques inYeast,HepB(Yeast)]10μg成人免疫失败的因素,为制定成人HepB接种方案提供依据。方法随机选取≥18岁易感人群,按0、1、6个月免疫程序接种HepB(Yeast)10μg,对免疫失败者进行病例对照研究。结果成人接种10μgHepB(Yeast)免疫失败率为12.99%。免疫失败人群吸烟率、肥胖率、乙肝家族史及微量乙肝病毒(Hepatitis BVirus,HBV)感染率均高于免疫成功人群,差异有显著的统计学意义。结论成人接种10μgHepB(Yeast)免疫失败与吸烟、肥胖、乙肝家族史、微量HBV感染有关。展开更多
文摘目的探讨成人接种60μg重组乙型肝炎疫苗(酿酒酵母)的免疫成功率和效果。方法选择我县200名16岁以上已进行乙肝疫苗免疫且没有抗体产生的人群,由深圳康泰生物制品股份有限公司提供60μg重组乙型肝炎疫苗220支,批号20100732-1,一针接种后1个月采血,进行血清免疫学检测。结果接种人群均未出现异常反应。接种一针后1个月,阳转率达98%,抗-HBs几何平均滴度(GMT)为150.88 m IU/m L。结论60μg重组乙型肝炎疫苗安全性良好,免疫成功率高,可用于成人乙肝疫苗加强免疫。
文摘A novel second-order nonlinear optical chromophore (DCDHF-2-V) was synthesized from 3-Hydroxy-3-methyl-2-butanae, propanedinitrile and 4-diethylaminobenzaldehyde by aldol condensation reaction. Molecular structural characterization was investigated by elemental analysis, FTIR, and 1H-NMR spectra. The melting point obtained from DSC thermogram was almost 251 ℃, and the compound shows a thermal stability up to 270 ℃. Second-order NLO properties of the chro- mophore were measured by solvatochromic method. From the quantum-mechanical two-level model, it can be obtained that the value of DCDHF-2-V is 6520 × 10-48 esu at the wavelength of 1064 nm.
文摘目的探讨重组乙型肝炎(乙肝)疫苗(酵母)[Hepatitis B Vaccine Made by Recombinant DNA Techniques inYeast,HepB(Yeast)]10μg成人免疫失败的因素,为制定成人HepB接种方案提供依据。方法随机选取≥18岁易感人群,按0、1、6个月免疫程序接种HepB(Yeast)10μg,对免疫失败者进行病例对照研究。结果成人接种10μgHepB(Yeast)免疫失败率为12.99%。免疫失败人群吸烟率、肥胖率、乙肝家族史及微量乙肝病毒(Hepatitis BVirus,HBV)感染率均高于免疫成功人群,差异有显著的统计学意义。结论成人接种10μgHepB(Yeast)免疫失败与吸烟、肥胖、乙肝家族史、微量HBV感染有关。