Extended π-conjugated N-containing heteroaromatic hexacarboxylate organic anode for high performance rechargeable batteries

Organic electrode materials are desirable for green and sustainable Li-ion batteries(LIBs) due to their light-weight, low cost, abundance and multi-electron transfer reactions during battery operation. However, the successful utilization of organic electrodes is hindered by their poor electrical conductivity and low cyclic stability. Herein, a facile synthesis of π-conjugated N-containing heteroaromatic hexacarboxylate(Li6-HAT) compound and its electrochemical performance as an anode material in LIBs is reported.The as-synthesized Li6-HAT electrode renders an ultrahigh initial capacity of 1126.3 m Ah g^(-1) at the current density of 100 m A g^(-1). Moreover, π-conjugated N-containing heteroaromatic center provide excellent reversibility of(de)lithiation process, resulting in excellent capacity retention. Furthermore, a combination of density functional theory(DFT) calculations, in-situ Fourier transform infrared(FTIR) and ex-situ X-ray photoelectron spectroscopy(XPS) characterization reveal that the π-conjugated nitrogen and carboxyl oxygen act as electrochemically active sites during the charge/discharge process. The current work provides novel insights into the charge storage mechanism of organic electrodes and opens up avenues for further development and utilization of organic electrodes in Li-ion batteries.

EFFECT OF CIS-9, TRANS-11-CONJUGATED LINOLEIC ACID ON CELL CYCLE OF MAMMARY ADENOCARCINOMA CELLS(MCF-7)

Objective: To determine the effect of cis-9, trans-1 1-conjugated linoleic acid on the cell cycle of mammary cancer cells (MCF-7) and the possible mechanism of the inhibitory effect of c9,t11-CLA. Methods: Using cell culture and immunocytochemical techniques, we examined the cell growth, DNA synthesis, expression of PCNA, cyclin A, B1, D1, p16ink4a and p21cip/waf1 of MCF-7 cells at various c9,t11-CLA concentrations (25μM, 50μM, 100μM and 200μM), at 24h and 48h. 96% ethand was used as negative control. Results: The cell growth and DNA synthesis of MCF-7 cells were inhibited by c9,t11-CLA. After treatment with various doses of c9,t11-CLA mentioned above for 8 days, the inhibition frequency was 27.18%, 35.43%, 91.05%, and 92.86%, respectively. Inhibitory effect of c9,t11-CLA on DNA synthesis (except for 25μM, 24h) was demonstrated by significantly less incorporation of 3H-TdR than the negative control (P<0.05 and P<0.01). To further investigate the influence of the cell cycle progression, we found that c9,t11-CLA may arrest the cell cycle of MCF-7 cells. Immunocytochemical staining demonstrated that incubation with different concentration of c9,t11-CLA at various times significantly decreased the expression of PCNA, Cyclin A, B1, D1 in MCF-7 cells compared to the negative control (P<0.01), whereas the expression of p16ink4a and p21cip/waf1, cyclin-dependent kinases inhibitors (CDKI), were increased. Conclusions: The cell growth and proliferation of MCF-7 cells is inhibited by c9,t11-CLA via blocking cell cycle, accompanying reduced expression of cyclin A, B1, D1 and enhanced expression of CDKI (p16ink4a and p21cip/waf1).

MXene Hollow Spheres Supported by a C–Co Exoskeleton Grow MWCNTs for Efficient Microwave Absorption

High-performance microwave absorption(MA) materials must be studied immediately since electromagnetic pollution has become a problem that cannot be disregarded. A straightforward composite material, comprising hollow MXene spheres loaded with C–Co frameworks, was prepared to develop multiwalled carbon nanotubes(MWCNTs). A high impedance and suitable morphology were guaranteed by the C–Co exoskeleton, the attenuation ability was provided by the MWCNTs endoskeleton, and the material performance was greatly enhanced by the layered core–shell structure. When the thickness was only 2.04 mm, the effective absorption bandwidth was 5.67 GHz, and the minimum reflection loss(RLmin) was-70.70 d B. At a thickness of 1.861 mm, the sample calcined at 700 ℃ had a RLmin of-63.25 d B. All samples performed well with a reduced filler ratio of 15 wt%. This paper provides a method for making lightweight core–shell composite MA materials with magnetoelectric synergy.

Four new lanostane triterpenoids featuring extendedπ-conjugated systems from the stems of Kadsura coccinea

Four new 14(13→12)-abeolanostane triterpenoids featuring extendedπ-conjugated systems,kadcoccitanes E-H(1-4),were obtained from the stems of Kadsura coccinea through using a HPLC−UV-guided approach.Their structural and configurational determination was accomplished through extensive spectroscopic analysis coupled with quantum chemical calculations.Kadcoccitanes E-H were tested for their cytotoxic activities against five human tumor cell lines(HL-60,A-549,SMMC-7721,MDA-MB-231,SW-480)but none of them exhibited activities at the concentration 40μM.

Three New -CF3, -CN Containing <i>π</i>-Conjugated Heteroaromatic Compounds: Synthesis, Crystal Structure and Photoelectronic Properties

Three new π-conjugated hetero aromatic materials consisting of pyridine 3a, furan 3b, and thiophene 3c have been synthesized by Knoevenagel condensation reaction. These molecules have been characterized by 1H NMR, EI-MS and single crystal X-ray diffraction analysis. Molecule 3a crystallized under monoclinic system with space group C2/c, molecule 3b crystallized under triclinic system with space group P-1 and the molecule 3c crystalized under triclinic system with space group P-1. The optoelectronic properties of these compounds have been studied.Molecules 3a, 3b and 3c showed strong absorption maxima wavelengths at 300, 419 and 418 nm, respectively. The molar extinction coefficients (ε) of the compounds 3a, 3b and 3c suggested that molecule 3b has better ability to absorb UV light;molecule 3a has better fluorescence intensity than molecule 3b and 3c. Low energy gaps of HOMO and LUMO energy levels of these compounds suggests that these compounds may be a promising new class of lead compounds for developing high performance semiconductor materials. Compounds 3a, 3b and 3c has emissions near to blue light, a slight modification of the structures by extending conjugation may find important applications in optoelectronic devices as blue light emitters in organic light-emitting devices for the development of new generation organic semiconducting materials.

Ageing-related bone and immunity changes:insights into the complex interplay between the skeleton and the immune system

Ageing as a natural irreversible process inherently results in the functional deterioration of numerous organ systems and tissues,including the skeletal and immune systems.Recent studies have elucidated the intricate bidirectional interactions between these two systems.

Rational design of carbon skeleton interfaces for highly reversible sodium metal battery anodes

Sodium metal batteries(SMBs)have attracted increasing attention over time due to their abundance of sodium resources and low cost.However,the widespread application of SMBs as a viable technology remains a great challenge,such as uneven metallic deposition and dendrite formation during cycling.Carbon skeletons as sodiophilic hosts can alleviate the dendrite formation during the plating/stripping.For the carbon skeleton,how to rationalize the design sodiophilic interfaces between the sodium metal and carbon species remains key to developing desirable Na anodes.Herein,we fabricated four kinds of structural features for carbon skeletons using conventional calcination and flash Joule heating.The roles of conductivity,defects,oxygen content,and the distribution of graphite for the deposition of metallic sodium were discussed in detail.Based on interface engineering,the J1600 electrode,which has abundant Na-C species on its surface,showed the highest sodiophilic.There are uniform and rich F-Na species distributed in the inner solid electrolyte interface layer.This study investigated the different Na-deposition behavior in carbon hosts with distinct graphitic arrangements to pave the way for designing and optimizing advanced electrode materials.

Vacancy defect MoSeTe embedded in N and F co-doped carbon skeleton for high performance sodium ion batteries and hybrid capacitors

Sodium-ion batteries(SIBs) and hybrid capacitors(SIHCs) have garnered significant attention in energy storage due to their inherent advantages,including high energy density,cost-effectiveness,and enhanced safety.However,developing high-performance anode materials to improve sodium storage performa nce still remains a major challenge.Here,a facile one-pot method has been developed to fabricate a hybrid of MoSeTe nanosheets implanted within the N,F co-doped honeycomb carbon skeleton(MoSeTe/N,F@C).Experimental results demonstrate that the incorporation of large-sized Te atoms into MoSeTe nanosheets enlarges the layer spacing and creates abundant anion vacancies,which effectively facilitate the insertion/extraction of Na^(+) and provide numerous ion adsorption sites for rapid surface capacitive behavior.Additionally,the heteroatoms N,F co-doped honeycomb carbon skeleton with a highly conductive network can restrain the volume expansion and boost reaction kinetics within the electrode.As anticipated,the MoSeTe/N,F@C anode exhibits high reversible capacities along with exceptional cycle stability.When coupled with Na_(3)V_(2)(PO_(4))_(3)@C(NVPF@C) to form SIB full cells,the anode delivers a reversible specific capacity of 126 mA h g^(-1) after 100 cycles at 0.1 A g^(-1).Furthermore,when combined with AC to form SIHC full cells,the anode demonstrates excellent cycling stability with a reversible specific capacity of50 mA h g^(-1) keeping over 3700 cycles at 1.0 A g^(-1).In situ XRD,ex situ TEM characterization,and theoretical calculations(DFT) further confirm the reversibility of sodium storage in MoSeTe/N,F@C anode materials during electrochemical reactions,highlighting their potential for widespread practical application.This work provides new insights into the promising utilization of advanced transition metal dichalcogenides as anode materials for Na^(+)-based energy storage devices.

Terpene extract from the stem of Celastrus orbiculatus inhibits actin cytoskeleton remodelling in gastric cancer cells by regulating the protein interaction between PTBP1 and ACTN4

Adjuvant chemoradiotherapy,molecular targeted therapy,and immunotherapy are frequently employed to extend the survival of patients with advanced gastric cancer(GC).However,most of these treatments have toxic side effects,drug resistance,and limited improvements in survival and quality of life.Therefore,it is crucial to discover and develop new medications targeting GC that are highly effective and have minimal toxicity.In previous studies,the total terpene extract from the stem of Celastrus orbiculatus demonstrated anti-GC activity;however,the specific mechanism was unclear.Our research utilising coimmunoprecipitation-mass spectrometry(Co-IP-MS),polypyrimidine tract binding protein 1(ptbp1)clustered regularly interspaced short palindromic repeat-associated protein 9(Cas9)-knockout(KO)mouse model,tissue microarray,and functional experiments suggests that alpha actinin-4(ACTN4)could be a significant biomarker of GC.PTBP1 influences actin cytoskeleton restructuring in GC cells by interacting with ACTN4.Celastrus orbiculatus stem extract(COE)may directly target ACTN4 and affect the interaction between PTBP1 and ACTN4,thereby exerting anti-GC effects.

中华美学史的性质及内在逻辑论

对于中华美学史的性质及内在逻辑,可以从五个方面展开论述:第一,中华美学的民族性。中华美学是中华民族的美学,中华民族文化以汉文化为灵魂,却绝不只是汉族文化,它熔铸了生活在中国大地上的诸多民族的文化精神,突出体现了中华民族共同的理念、精神、传统。第二,中华美学的国家性。中华美学的国家性奠基于周朝,周朝的礼乐文化既是政治文化,又是审美文化。中华文化中的主要学派儒、道、墨等的美学思想均见出鲜明的国家性。第三,中华美学的文化骨架。其根植于中华文化的三大流派:儒、道、释。儒家美学重社会,道家美学重自然,释家美学重心性。三者相对而又互补,共同构成中华美学的文化骨架。第四,中华美学的诗性品位。《诗经》《楚辞》和唐诗的巨大影响构建了中华美学的诗性品位。第五,中华美学的基本精神。其体现在对审美本体论的认识上,道家的美在自然与儒家的美在文明的统一,构成了中华美学的基本精神。

基于UFAC应力吸收层的抗反射裂缝性能评价

目的为了解决“白加黑”技术中的反射裂缝问题,针对目前常用的悬浮密实型高弹改性沥青混合料(super flexible asphalt concrete,SFAC)应力吸收层变形量较大、容易造成上部沥青加铺层不利于受力的缺陷,方法提出基于CAVF法和富沥青理念优化设计的骨架密实型UFAC应力吸收层。采用有限元ABAQUS数值模拟方法对“白加黑”路面结构进行受力分析,并通过加速加载试验、冲击韧性试验和劈裂试验对材料与结构的抗反射裂缝性能进行评价。结果重载条件下,UFAC应力吸收层和高弹改性沥青应力吸收层的竖向位移相差5.93×10^(-2)mm,沥青加铺层底部所受竖向压应力σy、最大主应力σ_(max)、最大剪应力τ_(12)分别降低24%,32.3%,27.7%。当路面存在严重脱空或常规脱空情况时,基于UFAC应力吸收层的路面结构比GAC加铺路面结构的抗疲劳开裂性能分别提升48%,36%。与传统的悬浮型砂粒式AC-5应力吸收层相比,UFAC-5应力吸收层的冲击韧性增加60.8%,劈裂抗拉强度提高16.8%。结论基于UFAC应力吸收层的沥青加铺技术,通过增大常规改性沥青膜厚保证必要的疲劳抗拉能力,并采用骨架密实型级配显著提高集料间的嵌挤能力和内摩阻力,减小层间结构变形,可有效减缓沥青加铺层反射裂缝的产生与发展。

Skeletonization技术及其在深地震反射剖面解释中的应用

"深部探测技术与实验研究"(SINOPROBE)专项的启动揭开了中国"入地"计划的序幕.大规模的深地震反射剖面是该计划最重要的组成部分之一,如何从深地震反射剖面中获取更多有用的信息成为我们即将面临的重要课题.Skeletonization技术是西方国家在实施深部探测计划时发展的一项深地震剖面信息提取分析技术,对我们具有重要的借鉴意义.本文在研究前人工作的基础上,综述了Skeletonization技术的基本原理及其在国内外的发展,并在此基础上介绍了该技术在深地震反射剖面解释中的应用,最后结合我国刚刚启动的SINOPROBE计划对其进一步的发展进行了展望.

乳内动脉skeleton取材法在冠状动脉旁路移植术中的应用

目的 评价乳内动脉skeleton取材法在冠状动脉旁路移植术（CABG）中的应用及其效果。方法 277例接受CABG的患者（其中合并糖尿病33例）在术中分离乳内动脉的过程中，仅使用剪刀和钛夹来分离乳内动脉，即不附带任何周围组织的skeleton取材法游离一侧或两侧乳内动脉，其中21例糖尿病患者取用双侧乳内动脉；并观察患者术中、术后的临床结果。采用非体外循环CABG5例，体外循环CABG272例。结果 体外循环时间60～217min，平均90．1min；主动脉阻断时间30～160min，平均53．3min。手术死亡率2．2％（6／277）。手术中见乳内动脉桥质量良好，动脉桥血流量满意；术后移植血管通畅，心绞痛症状消失。取用双侧乳内动脉和糖尿病患者亦未出现更高的胸骨感染率。手术后冠状动脉造影显示乳内动脉血管桥通畅。结论 乳内动脉skeleton取材法有良好的血管桥通畅率，对患者胸骨创伤较小，对糖尿病患者取用双侧乳内动脉不再是禁忌证。

Rock skeleton models and seismic porosity inversion

By substituting rock skeleton modulus expressions into Gassmann approximate fluid equation, we obtain a seismic porosity inversion equation. However, conventional rock skeleton models and their expressions are quite different from each other, resuling in different seismic porosity inversion equations, potentially leading to difficulties in correctly applying them and evaluating their results. In response to this, a uniform relation with two adjusting parameters suitable for all rock skeleton models is established from an analysis and comparison of various conventional rock skeleton models and their expressions including the Eshelby-Walsh, Pride, Geertsma, Nur, Keys-Xu, and Krief models. By giving the two adjusting parameters specific values, different rock skeleton models with specific physical characteristics can be generated. This allows us to select the most appropriate rock skeleton model based on geological and geophysical conditions, and to develop more wise seismic porosity inversion. As an example of using this method for hydrocarbon prediction and fluid identification, we apply this improved porosity inversion, associated with rock physical data and well log data, to the ZJ basin. Research shows that the existence of an abundant hydrocarbon reservoir is dependent on a moderate porosity range, which means we can use the results of seismic porosity inversion to identify oil reservoirs and dry or water-saturated reservoirs. The seismic inversion results are closely correspond to well log porosity curves in the ZJ area, indicating that the uniform relations and inversion methods proposed in this paper are reliable and effective.

基于Skeleton Design的脱粒装置交互式设计系统研究

针对联合收获机脱粒装置设计过程中装备结构复杂、参数化变形设计困难以及对设计人员专业素质要求高的问题,为寻求合适的参数化设计手段,研究了基于Skeleton Design(骨架设计)的脱粒装置交互式设计系统。以纹杆滚筒式脱粒装置为研究对象,引入Skeleton Design过程体的概念,结合纹杆滚筒式脱粒装置的总体设计过程,实现脱粒装置的个性化设计与参数化建模。以VS(Microsoft Visual Studio)环境下VB.NET为开发语言,应用CATIA(Computer aided tri-dimensional interface application)二次开发接口技术与SQL Server数据库管理,将模型、参数、知识信息等数字化资源与操作平台组织起来,联合运用,通过人机交互的方式进行产品设计。系统测试表明,该系统能在降低设计人员专业性、提高开发产品准确性的同时,提高设计效率、缩短设计周期,并且易于理解和应用,增强了模型的知识继承与重用性,满足脱粒装置个性化设计要求。

Skeleton extraction of boiler flame images based on mathematical morphology

In this paper, a method and algorithm of skeleton extraction based on binary mathematical morphology is presented. Sequential structuring elements (SEs) is also studied, which is the key problem of skeleton extraction. The examples of boiler flame image processing show that the detected skeletons can present the geometric shape of flame images well.

神经网络Skeletonization算法在优化锅炉运行参数中的应用

对将神经网络Skeletonization算法进行改进,运用到优化调整锅炉性能参数的方法,用神经网络模型预测锅炉运行中需要优化的性能参数。通过神经网络的学习,模拟性能参数的影响因素与性能参数之间的映射函数,再通过改进Skeletonization算法对网络模型进一步计算,找出哪些影响因素对性能参数的影响较大,为快速有效准确的机组运行优化提供指导依据和方向。这种方法不仅能为机组运行优化提供直观的理论根据,同时对锅炉的运行不产生负面影响,可以实现在线优化运行。通过计算影响因素的权重值,对性能参数准确预报,为锅炉机组的性能优化调整提供便捷、准确、全面的方案。

Oviraptorosaurian Eggs (Dinosauria) with Embryonic Skeletons Discovered for the First Time in China

Two elongatoolithid dinosaur eggs from the Upper Cretaceous of Ganzhou, Jiangxi Province and the embryonic skeletons they bear are described. They represent the first oviraptorosaurian eggs with embryonic skeletons in China and provide the first example that an oospecies can be correlated to certain dinosaur taxon/taxa. The two eggs are the same as the pair of the eggs inside a female oviraptorosaurian pelvis from the same horizon of the same area in both macro- and micro-structures of the egg shells, and can he referred to the oospecies, Macroolithus yaotunensis Zhao, 1975. The morphology of the preserved part of the embryonic skeletons indicates that they may have been laid by an oviraptorid, Heyuannia huangi from Guangdong Province or a closely related oviraptorosaurian, which may have been lived in the Ganzhou area too in the Late Cretaceous. The embryonic skeletons of the two eggs are not in the same developing stage. In one of the eggs, the postzygapophysis of the preserved vertebrae are well ossified, indicating that it was just hatched.

Effects of Ultraviolet Radiation on Skeleton Development of Broiler Chickens

Seven hundred and twenty one-day-old AA broiler chickens were randomly allocated into two groups （male and female for half）, and put into two identical closed houses with different lighting programs. The first house was illuminated by using common incandescence light, and the second one was added with ultraviolet radiation light from the second week onwards. The birds lived in a floor with litters and free access to feed and water. Temperature, humidity and immune programs in the two houses were similar. The results showed that under ultraviolet radiation, the growth speed of skeleton increased （the shank length was significantly increased in the third week, P〈0.05; the leg muscle weight was significantly improved by 3.87%, P〈 0.05）; the skeleton quality improved （the density of skeleton mineralization was significantly increased by 6.11%, P 〈 0.01; serum calcium, phosphorus, and alkaline phosphatase activity were all improved）; and the growth performance was improved （feed conversion ratio was improved by 1.4% averagely; the uniformity of body weight, the shank length, the inclined body length and body height were significantly improved） in broiler chicken.

The Most Complete Pistosauroid Skeleton from the Triassic of Yunnan,China

A new specimen discovered from the Falang Formation in northeastern Yunnan represents the most complete skeleton of Triassic pistosauroids. The new specimen is referred to Yunguisaurus Cheng et al., 2006 on the basis of the skull features, such as the presence of a separated nasal entering the external naris, a large pineal foramen located at the frontal/parietal suture and an interpterygoid vacuity with a narrow anterior extension. The new specimen differs from the type species of Yunguisaurus liae Cheng et al., 2006 in some aspects. Most of these differences can be attributed to ontogenetic variations. The new specimen is provisionally considered as Yunguisaurus cf. liae although its relatively short snout of the skull and slenderer hyoid may not be explained ontogenetically. Whether or not the new specimen represents a different taxon has to wait for a detailed study of the whole skeleton.