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Cryogenic springback of 2219-W aluminum alloy sheet through V-shaped bending
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作者 Xiao-bo FAN Qi-liang WANG +1 位作者 Fang-xing WU Xu-gang WANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第10期3185-3193,共9页
A V-shaped bending device was established to evaluate the effects of temperature and bending fillet radius on springback behavior of 2219-W aluminum alloy at cryogenic temperatures.The cryogenic springback mechanism w... A V-shaped bending device was established to evaluate the effects of temperature and bending fillet radius on springback behavior of 2219-W aluminum alloy at cryogenic temperatures.The cryogenic springback mechanism was elucidated through mechanical analyses and numerical simulations.The results indicated that the springback angle at cryogenic temperatures was greater than that at room temperature.The springback angle increased further as the temperature returned to ambient conditions,attributed to the combined effects of the “dual enhancement effect” and thermal expansion.Notably,a critical fillet radius made the springback angle zero for 90° V-shaped bending.The critical fillet radius at cryogenic temperatures was smaller than that at room temperature,owing to the influence of temperature variations on the bending moment ratio between the forward bending section at the fillet and the reverse bending section of the straight arm. 展开更多
关键词 2219-W aluminum alloy cryogenic forming V-shape bending SPRINGBACK critical fillet radius
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GENERAL SOLUTION OF THE OVERALL BENDING OF FLEXIBLE CIRCULAR RING SHELLS WITH MODERATELY SLENDER RATIO AND APPLICATIONS TO THE BELLOWS (Ⅲ)-CALCULATION FOR C-SHAPED BELLOWS
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作者 ZHU Wei-ping(朱卫平) +1 位作者 HUANG Qian(黄黔) 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2002年第10期1153-1163,共11页
This is one of the applications of Part (Ⅰ), in which the angular stiffness, the lateral stiffness and the corresponding stress distributions of C_shaped bellows were calculated. The bellows was divided into protrudi... This is one of the applications of Part (Ⅰ), in which the angular stiffness, the lateral stiffness and the corresponding stress distributions of C_shaped bellows were calculated. The bellows was divided into protruding sections and concave sections for the use of the general solution (Ⅰ), but the continuity of the stress resultants and the deformations at each joint of the sections were entirely satisfied. The present results were compared with those of the other theories and experiments, and are also tested by the numerically integral method. It is shown that the governing equation and the general solution (Ⅰ) are very effective. 展开更多
关键词 theory of flexible shell circular ring shell C_shaped bellows overall bending general solution
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GENERAL SOLUTION OF THE OVERALL BENDING OF FLEXIBLE CIRCULAR RING SHELLS WITH MODERATELY SLENDER RATIO AND APPLICATIONS TO THE BELLOWS (Ⅳ)-CALCULATION FOR U-SHAPED BELLOWS
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作者 ZHU Wei-ping(朱卫平) +1 位作者 HUANG Qian(黄黔) 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2002年第10期1164-1169,共6页
This is one of the applications of Part (Ⅰ),in which the angular stiffness, and the corresponding stress distributions of U_shaped bellows were discussed. The bellows was divided into protruding sections, concave sec... This is one of the applications of Part (Ⅰ),in which the angular stiffness, and the corresponding stress distributions of U_shaped bellows were discussed. The bellows was divided into protruding sections, concave sections and ring plates for the calculation that the general solution (Ⅰ) with its reduced form to ring plates were used respectively, but the continuity of the surface stresses and the meridian rotations at each joint of the sections were entirely satisfied. The present results were compared with those of the slender ring shell solution proposed earlier by the authors, the standards of the Expansion Joint Manufacturers Association (EJMA), the experiment and the finite element method. It is shown that the governing equation and the general solution (Ⅰ) are very effective. 展开更多
关键词 theory of flexible shell circular ring shell U_shaped bellows pure bending general solution
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Numerical analysis of dimension precision of U-shaped aluminium profile rotary stretch bending 被引量:5
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作者 于忠奇 林忠钦 《中国有色金属学会会刊:英文版》 EI CSCD 2007年第3期581-585,共5页
In order to enhance the dimension precision of bent part, advanced bending technologies is requested recently. Rotary stretch bending(RSB) is a suitable technology to realize high precision of bent part. The effect of... In order to enhance the dimension precision of bent part, advanced bending technologies is requested recently. Rotary stretch bending(RSB) is a suitable technology to realize high precision of bent part. The effect of processing parameters, namely the side pressure and the stretching force, on the dimension precision of aluminium profile RSB part was studied by finite element method. The numerical simulation of the U-shaped aluminium profile RSB was carried out, and the validity of the simulation was checked. Parametric analysis shows that the section distortion of the U-shaped profile LY12M bent part decreases with the increasing of the side pressure, whereas the springback of curvature increases, and that both of the section distortion and the springback of curvature decrease with the increasing of the stretching force, moreover, the uniformity of curvature of the bent part is clearly enhanced with the increasing of the stretching force. The results above prove that RSB technology can better improve the dimension precision of aluminium profile bent part. 展开更多
关键词 数值分子 旋转拉伸 铝材料 回弹性能
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A smart finger patch with coupled magnetoelastic and resistive bending sensors
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作者 Ziyi Dai Mingrui Wang +4 位作者 Yu Wang Zechuan Yu Yan Li Weidong Qin Kai Qian 《Journal of Semiconductors》 2025年第1期194-203,共10页
In the era of Metaverse and virtual reality(VR)/augmented reality(AR),capturing finger motion and force interactions is crucial for immersive human-machine interfaces.This study introduces a flexible electronic skin f... In the era of Metaverse and virtual reality(VR)/augmented reality(AR),capturing finger motion and force interactions is crucial for immersive human-machine interfaces.This study introduces a flexible electronic skin for the index finger,addressing coupled perception of both state and process in dynamic tactile sensing.The device integrates resistive and giant magnetoelastic sensors,enabling detection of surface pressure and finger joint bending.This e-skin identifies three phases of finger action:bending state,dynamic normal force and tangential force(sweeping).The system comprises resistive carbon nanotubes(CNT)/polydimethylsiloxane(PDMS)films for bending sensing and magnetoelastic sensors(NdFeB particles,EcoFlex,and flexible coils)for pressure detection.The inward bending resistive sensor,based on self-assembled microstructures,exhibits directional specificity with a response time under 120 ms and bending sensitivity from 0°to 120°.The magnetoelastic sensors demonstrate specific responses to frequency and deformation magnitude,as well as sensitivity to surface roughness during sliding and material hardness.The system’s capability is demonstrated through tactile-based bread type and condition recognition,achieving 92%accuracy.This intelligent patch shows broad potential in enhancing interactions across various fields,from VR/AR interfaces and medical diagnostics to smart manufacturing and industrial automation. 展开更多
关键词 human machine interface flexible sensor wearable sensor giant magnetoelastic effect inward bending sensor
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Deformation Analysis on Shear-Bending of Ring-Shaped Piezoelectric Actuator
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作者 康新 董帅 何小元 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2015年第6期585-590,共6页
Deformation of a simple single piezoelectric actuator is usually quite small.A ring-shaped piezoelectric actuator with large piezoelectrically generated displacement was proposed.The thickness of the actuator was1 mm,... Deformation of a simple single piezoelectric actuator is usually quite small.A ring-shaped piezoelectric actuator with large piezoelectrically generated displacement was proposed.The thickness of the actuator was1 mm,and the inner and outer diameters were 4 mm and 40 mm,respectively.The ring-shaped actuator was made of BiScO_3-PbTiO_3(BS-PT)ceramic and polarized in radial direction.An electric field was applied to thickness direction and a large shear-bending deformation emerged.Then Rayleigh-Ritz method and Bessel functions were adopted to analyze the shear-bending deformation.Results show that under an electric field of 7.5kV/cm,the maximum displacement at the inner edge of the actuator reached 5.07μm,which agreed well with the corresponding experimental results. 展开更多
关键词 ring-shaped piezoelectric actuator shear-bending Rayleigh-Ritz method
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基于IP联合蛋白质组学探讨ENG互作蛋白在bEnd.3细胞中的作用
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作者 陈清杰 李奥迪 +4 位作者 季慧敏 孙艺瑄 蒋越 叶子奇 潘荣 《湖北科技学院学报(医学版)》 2024年第6期461-466,F0002,共7页
目的本研究拟筛选并验证在脑微血管内皮细胞(bEnd.3)中Endoglin(ENG)的互作蛋白及其作用。方法采用蛋白质组学和生物信息学技术鉴定并富集ENG互作蛋白,对这些互作蛋白进行亚细胞定位、GO功能注释、IPR注释和蛋白互作网络等分析。将以上... 目的本研究拟筛选并验证在脑微血管内皮细胞(bEnd.3)中Endoglin(ENG)的互作蛋白及其作用。方法采用蛋白质组学和生物信息学技术鉴定并富集ENG互作蛋白,对这些互作蛋白进行亚细胞定位、GO功能注释、IPR注释和蛋白互作网络等分析。将以上分析筛选出的ENG互作蛋白,采用免疫共沉淀(IP)实验、细胞免疫荧光(IF)和蛋白免疫印迹(WB)技术进行验证和对比,探究ENG互作蛋白在棕榈酸(PA)、基因沉默和过表达ENG处理bEnd.3细胞中的表达变化及作用。结果通过蛋白质组学分析,bEnd.3细胞中ENG互作蛋白在亚细胞定位分析中细胞骨架相关成分呈现出较高的占比;通过GO注释和IPR注释进一步发现,是细胞骨架中的中间纤维和微丝蛋白呈现较高的富集状态。ENG与细胞骨架蛋白互作热力图结果显示,与对照组相比,PA处理的bEnd.3细胞中微丝蛋白Filamin B(Flnb)数值显著降低。IP和IF结果显示,bEnd.3细胞中ENG与Flnb存在蛋白互作和共定位情况。WB结果显示,bEnd.3细胞在PA处理条件下,ENG和Flnb蛋白表达均下降;在ENG沉默条件下,Flnb蛋白随ENG表达的减少而降低;在ENG过表达条件下,Flnb蛋白随ENG表达的增加而升高。结论ENG互作蛋白广泛参与到多种相关的生物途径以及信号通路之中,ENG在bEnd.3细胞中与Flnb蛋白存在相互作用且二者具有共定位现象,ENG还能够调控PA处理的bEnd.3细胞Flnb蛋白表达水平。 展开更多
关键词 ENG Flnb 互作蛋白 bend.3 棕榈酸
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Evaluation of “J”-shaped Uterine Incision during Caesarean Section in Patients with Placenta Previa:A Retrospective Study 被引量:8
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作者 邹丽 钟少平 +2 位作者 赵茵 朱剑文 陈莉娟 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2010年第2期212-216,共5页
This study evaluated the efficacy and safety of "J"-shaped uterine incision for caesarean section for patients diagnosed with placenta previa. A total of 55 consecutive cases of placenta previa treated in Union Hosp... This study evaluated the efficacy and safety of "J"-shaped uterine incision for caesarean section for patients diagnosed with placenta previa. A total of 55 consecutive cases of placenta previa treated in Union Hospital were retrospectively analyzed over a period of two years and 10 months. The subjects were divided into two groups with respect to the uterine incision. Twenty-four pregnant women with placenta previa who were indicated for caesarean section underwent the procedure using a new "J"-shaped uterine incision and 31 pregnant women with placenta previa received caesarean section that used the traditional transverse incision. The two groups were compared in terms of operation time, estimated blood loss, infant expulsion time, exhaust time and postoperative recovery. Meanwhile, comparison was also made in neonatal clinical data between the two groups. Compared with the "J"-shaped incision group, the traditional incision group had a lower Apgar scores (P〈0.05). However, there existed no statistically significant differences in the overall time of operation and postoperative period of breaking wind (P〉0.05). It is concluded that, with caesarean section for placenta previa patients, the "J"-shaped uterine incision significantly decreases intraoperative blood loss and facilitates the fetal delivery. 展开更多
关键词 "J"-shaped incision caesarean section placenta previa
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Shortening turn-on delay of SiC light triggered thyristor by7-shaped thin n-base doping profile 被引量:2
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作者 Xi Wang Hong-Bin Pu +1 位作者 Qing Liu Li-Qi An 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第10期622-627,共6页
A new 4 H–SiC light triggered thyristor(LTT) with 7-shaped thin n-base doping profile is proposed and simulated using a two-dimensional numerical method. In this new structure, the bottom region of the thin n-base ... A new 4 H–SiC light triggered thyristor(LTT) with 7-shaped thin n-base doping profile is proposed and simulated using a two-dimensional numerical method. In this new structure, the bottom region of the thin n-base has a graded doping profile to induce an accelerating electric field and compensate for the shortcoming of the double-layer thin n-base structure in transmitting injected holes. In addition, the accelerating electric field can also speed up the transmission of photongenerated carriers during light triggering. As a result, the current gain of the top pnp transistor of the SiC LTT is further increased. According to the TCAD simulations, the turn-on delay time of the SiC LTT decreases by about 91.5% compared with that of previous double-layer thin n-base SiC LTT. The minimum turn-on delay time of the SiC LTT is only 828 ns,when triggered by 100 mW/cm^2 ultraviolet light. Meanwhile, there is only a slight degradation in the forward blocking characteristic. 展开更多
关键词 silicon carbide light triggered thyristor 7-shaped doping profile turn-on delay
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Research on vibration characteristics of L-shaped plate using a mobility power flow approach 被引量:2
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作者 CHEN Xiao-li SHENG Mei-ping 《Journal of Marine Science and Application》 2007年第3期12-16,共5页
L-shaped plates have become an important focuses in structural vibration research. To determine their vibration characteristics, this paper applied a mobility power flow method. Firstly, the L-shaped plate was divided... L-shaped plates have become an important focuses in structural vibration research. To determine their vibration characteristics, this paper applied a mobility power flow method. Firstly, the L-shaped plate was divided into two substructures to simplify analysis. The coupled bending moment was then deduced by applying a continuous vibration property on the common edge. Next, the response on any point of the plate and the input and transmitted power flow formulas were calculated. Numerical simulations showed the distribution of the coupled bending moment and the response of the whole structure. The validity of this method was verified by the SEA approach. 展开更多
关键词 L-shaped plate vibration response mobility power flow coupled bending moment
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Analysis and Simulation of S-shaped Waveguide in Silicon-on-insulator 被引量:1
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作者 WANGZhang-tao FANZhong-cao XIAJin-song CHENShao-wu YuJinzhong 《Semiconductor Photonics and Technology》 CAS 2004年第2期78-81,共4页
The simulation and analysis of S-shaped waveguide bend are presented.Bend radius larger than 30 mm assures less than 0.5 dB radiation loss for a 4-μm-wide silicon-on-insulator waveguide bend with 2-μm etch depth.Int... The simulation and analysis of S-shaped waveguide bend are presented.Bend radius larger than 30 mm assures less than 0.5 dB radiation loss for a 4-μm-wide silicon-on-insulator waveguide bend with 2-μm etch depth.Intersection angle greater than 20° provides negligible crosstalk (<-30 dB) and very low insertion loss.Any reduction in bend radius and intersection angle is at the cost of the degradation of characteristics of bent waveguide and intersecting waveguide, respectively. 展开更多
关键词 BPM S-shaped bend SILICON-ON-INSULATOR
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Experimental,Numerical,and Analytical Studies on the Bending of Mechanically Lined Pipe 被引量:1
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作者 WEI Wen-bin YUAN Lin +1 位作者 ZHOU Jia-sheng LIU Zheng 《China Ocean Engineering》 SCIE EI CSCD 2024年第2期221-232,共12页
Mechanically lined pipe(MLP)is often used for offshore oil and gas transport because of its low cost and corrosion resistance.During installation and operation,the pipe may undergo severe bending deformation,which cau... Mechanically lined pipe(MLP)is often used for offshore oil and gas transport because of its low cost and corrosion resistance.During installation and operation,the pipe may undergo severe bending deformation,which causes the liner to separate from the outer pipe and buckles,affecting the stability of the whole line.In this paper,the buckling response of MLP subjected to bending is investigated to clarify its bending characteristics by employing both experiments,numerical simulation,as theoretical methods.Two types of MLPs were manufactured with GB 45 carbon steel(SLP)and Al 6061(ALP)used as the outer pipe material,respectively.The hydraulic expansion and bending experiments of small-scale MLPs are conducted.In addition to the ovalized shape of the cross-section for the SLP specimens,the copper liner was found to wrinkle on the compressive side.In contrast,the liner of ALP remains intact without developing any wrinkling and collapse mode.In addition,a dedicated numerical framework and theoretical models were also established.It was found both the manufacturing and bending responses of the MLP can be well reproduced,and the predicted maximum moment and critical curvatures are in good agreement with the experimental results. 展开更多
关键词 lined pipe bendING nonlinear ring theory BUCKLING PLASTICITY
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Effect of characteristics and distribution of Mg_(17)Al_(12)precipitates on tensile and bending properties of high-Al-containing Mg alloys 被引量:1
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作者 Sumi Jo Gyo Myeong Lee +2 位作者 Jong Un Lee Young Min Kim Sung Hyuk Park 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第2期779-793,共15页
This study investigates the effect of characteristics and distribution of Mg_(17)Al_(12)precipitates on the uniaxial tensile and three-point bending properties of extruded Mg alloys containing high Al contents.The ext... This study investigates the effect of characteristics and distribution of Mg_(17)Al_(12)precipitates on the uniaxial tensile and three-point bending properties of extruded Mg alloys containing high Al contents.The extruded Mg–9Al–1Zn–0.3Mn(AZ91)alloy contains lamellar-structured Mg_(17)Al_(12)discontinuous precipitates along the grain boundaries,which are formed via static precipitation during natural air cooling.The extruded Mg–11Al–1Zn–0.3Mn(AZ111)alloy contains spherical Mg_(17)Al_(12)precipitates at the grain boundaries and inside the grains,which are formed via dynamic precipitation during extrusion.Due to inhomogeneous distribution of precipitates,the AZ111 alloy consists of two different precipitate regions:precipitate-rich region with numerous precipitates and finer grains and precipitate-scarce region with a few precipitates and coarser grains.The AZ111 alloy exhibits a higher tensile strength than the AZ91 alloy because its smaller grain size and more abundant precipitates result in stronger grain-boundary hardening and precipitation hardening effects,respectively.However,the tensile elongation of the AZ111 alloy is lower than that of the AZ91 alloy because the weak cohesion between the dynamic precipitates and the matrix facilitates the crack initiation and propagation.During bending,a macrocrack initiates on the outer surface of bending specimen in both alloys.The AZ111 alloy exhibits higher bending yield strength and lower failure bending strain than the AZ91 alloy.The bending specimens of the AZ91 alloy have similar bending formability,whereas those of the AZ111 alloy exhibit considerable differences in bending formability and crack propagation behavior,depending on the distribution and number density of precipitates in the specimen.In bending specimens of the AZ111 alloy,it is found that the failure bending strain(ε_(f,bending))is inversely proportional to the area fraction of precipitates in the outer zone of bending specimen(A_(ppt)),with a relationship ofε_(f,bending)=–0.1A_(ppt)+5.86. 展开更多
关键词 Mg–Al alloy EXTRUSION bendING Precipitation Microstructure
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Learning curve for a surgeon in robotic pancreaticoduodenectomy through a“G”-shaped approach:A cumulative sum analysis
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作者 Zhi-Gang Wei Chao-Jie Liang +2 位作者 Yang Du Yong-Ping Zhang Yu Liu 《World Journal of Clinical Cases》 SCIE 2022年第14期4357-4367,共11页
BACKGROUND Robotic pancreaticoduodenectomy(RPD)can achieve similar surgical results to open and PD;however,RPD has a long learning curve and operation time(OT).To address this issue,we have summarized a surgical path ... BACKGROUND Robotic pancreaticoduodenectomy(RPD)can achieve similar surgical results to open and PD;however,RPD has a long learning curve and operation time(OT).To address this issue,we have summarized a surgical path to shorten the surgical learning curve and OT.AIM To investigate the effective learning curve of a“G”-shaped surgical approach in RPD for patients.METHODS A total of 60 patients,who received“G”-shaped RPD(GRPD)by a single surgeon in the First Hospital of Shanxi Medical University from May 2017 to April 2020,were included in this study.The OT,demographic data,intraoperative blood loss,complications,hospitalization time,and pathological results were recorded,and the cumulative sum(CUSUM)analysis was performed to evaluate the learning curve for GRPD.RESULTS According to the CUSUM analysis,the learning curve for GRPD was grouped into two phases:The early and late phases.The OT was 480±81.65 min vs 331±76.54 min,hospitalization time was 22±4.53 d vs 17±6.08 d,and blood loss was 308±54.78 mL vs 169.2±35.33 mL in the respective groups.Complications,including pancreatic fistula,bile leakage,reoperation rate,postoperative death,and delayed gastric emptying,were significantly decreased after this surgical technique.CONCLUSION GRPD can improve the learning curve and operative time,providing a new method for shortening the RPD learning curve. 展开更多
关键词 Robotic pancreaticoduodenectomy “G”-shaped approach Learning curve Cumulative sum analysis
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A Novel Open C-shaped Molar Band for Orthodontic Applications: Mechanical Characterizations and Clinical Trials
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作者 周珊 GUO Yang +3 位作者 WANG Peijun FU Wei XU Shiqian 张斌 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2016年第5期1174-1180,共7页
To evaluate the retention properties of the novel ‘C'-shaped molar bands at a laboratory level. Resin-modified glass ionomer cement(RMGIC) was used as a luting agent for the novel C-shaped molar band. The mechanic... To evaluate the retention properties of the novel ‘C'-shaped molar bands at a laboratory level. Resin-modified glass ionomer cement(RMGIC) was used as a luting agent for the novel C-shaped molar band. The mechanical properties of the band were examined and the retention performance was characterized in the mesial, distal and vertical directions. A clinical trial was conducted using a spilt-mouth design on 50 patients. The novel C-shaped molar bands fit most molars without a repeated try-in process.The use of both nanoHA coating and RMGIC enhanced the tensile(8.00 ± 1.8 MPa) and shear strengths(27.17 ± 8.6 MPa) of the molar bands, leading to high retention in vertical, mesial and distal directions( p 〈 0.001). In clinical trials, the C-shaped molar bands had a failure rate(15%) comparable to that of traditional bands, and 93% of the failed bands demonstrated an adhesive remnant index score of 0, corroborating the observation that no luting agent residue remained on the tooth surface in most cases. The novel C-shaped molar bands appear to be a promising appliance that requires further clinical investigations, and may be used effectively in orthodontics. 展开更多
关键词 Copen 'C'-shaped molar bands nano-hydroxyapatite resin-modified glass ionomer cement retention performance clinical trials
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An Inelastic Material Model for Lateral Torsional Buckling and Biaxial Bending of Steel W-Shapes
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作者 Barry T.Rosson 《Journal of Civil Engineering and Architecture》 2021年第12期599-603,共5页
A new material model for beam elements was developed for use as normalized tangent modulus expressions when performing 3-dimensional second-order inelastic analyses of steel I-section beams.The stiffness matrix of a 1... A new material model for beam elements was developed for use as normalized tangent modulus expressions when performing 3-dimensional second-order inelastic analyses of steel I-section beams.The stiffness matrix of a 14 degree-of-freedom beam element was updated to include the effects of yielding on St.Venant’s torsion and bimoment stiffness at the initial and terminal nodes.A validation study compared the new model’s results with those from published detailed finite element analyses and was found to be in very close agreement.A biaxial end-moment study with two different depth-to-flange-width ratios provided expected and consistent results over a range of moment conditions. 展开更多
关键词 Nonlinear analysis lateral torsional buckling biaxial bending stiffness reduction material model
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基于p38MAPK-PPARγ/NF-κB信号通路探讨消肿止痛合剂对血管内皮细胞bEND-3凋亡的影响 被引量:1
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作者 朱克玉 宋渊 +4 位作者 梁旭东 沈稼轩 张团庄 乔靖 刘涛 《辽宁中医杂志》 CAS 北大核心 2024年第4期149-152,I0002,共5页
目的从细胞及信号通路层面探讨消肿止痛合剂对皮瓣缺血再灌注损伤中血管内皮细胞凋亡的影响。方法血管内皮细胞bEND-3培养。TNF-α体外细胞凋亡诱导模型建立并将细胞分为:p38MAPK抑制剂组、PPARγ抑制剂组、NF-κB抑制剂组、模型对照组... 目的从细胞及信号通路层面探讨消肿止痛合剂对皮瓣缺血再灌注损伤中血管内皮细胞凋亡的影响。方法血管内皮细胞bEND-3培养。TNF-α体外细胞凋亡诱导模型建立并将细胞分为:p38MAPK抑制剂组、PPARγ抑制剂组、NF-κB抑制剂组、模型对照组、空白组。微丝绿色荧光探针观察细胞骨架微丝。RT-PCR法检测血管内皮细胞bEND-3细胞中p38MAPK、PPARγ、IκBα、NF-κBmRNA的表达。结果空白组中p38MAPK、PPARγ、IκBα、NF-κB的表达量无明显差异,模型对照组中p38MAPK与NF-κB的表达量最高,与模型对照组相比,p38MAPK抑制剂组bEnd.3细胞中p38MAPK与NF-κB的表达被抑制,PPARγ、IκBα表达量升高(P<0.05);PPARγ抑制剂组中PPARγ、IκBα、NF-κB的表达被抑制,p38MAPK表达量升高(P<0.05),NF-κB抑制剂组中p38MAPK与NF-κB的表达被抑制,IκBα与PPARγ的表达量升高(P<0.05);与空白组相比,p38MAPK抑制剂组与NF-κB抑制剂组中p38MAPK、PPARγ、IκBα、NF-κB的表达量升高(P<0.05),PPARγ抑制剂组中p38MAPK与NF-κB表达量明显升高,PPARγ、IκBα表达被抑制(P<0.05)。结论消肿止痛合剂可抑制bEND-3细胞凋亡,其机制与影响可能与p38MAPK-PPARγ/NF-κB信号通路有关。 展开更多
关键词 消肿止痛合剂 bend-3细胞 信号通路 皮瓣
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基于α-shape与SSA-XGBoost算法的无人机点云孔洞修补
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作者 宋晓辉 吕富强 +2 位作者 窦彩英 唐诗华 党梦鑫 《海洋测绘》 CSCD 北大核心 2024年第4期69-73,共5页
针对极限梯度提升树算法在进行无人机点云孔洞修补时核心超参数难以选取、点云孔洞修补范围识别困难以及孔洞修补精度较低等问题,提出基于麻雀搜索算法优化极限梯度提升树的点云孔洞修补方法。首先利用α-shape算法进行点云的孔洞识别,... 针对极限梯度提升树算法在进行无人机点云孔洞修补时核心超参数难以选取、点云孔洞修补范围识别困难以及孔洞修补精度较低等问题,提出基于麻雀搜索算法优化极限梯度提升树的点云孔洞修补方法。首先利用α-shape算法进行点云的孔洞识别,在此基础上,获取点云孔洞和周围点云的位置信息并将其作为模型的输入样本。再利用麻雀搜索算法优化极限梯度提升树算法中的核心超参数,构建SSA-XGBoost点云孔洞修补模型,并将该模型应用于无人机点云孔洞的修补中。最后将SSA-XGBoost与XGBoost、BP神经网络两组算法进行预测精度的对比。实验结果表明:SSA-XGBoost模型的预测结果相较于其它两组对比算法预测精度更高,在点云孔洞修补方面具有一定的意义。 展开更多
关键词 摄影测量 孔洞修补 α-shape算法 麻雀搜索算法 极限梯度提升树
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Discharge evolution law of debris flow based on a sharp bend physical modeling test
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作者 LU Ming SUN Hao +3 位作者 LIU Jinfeng Abrar HUSSAIN SHANG Yuqi FU Hang 《Journal of Mountain Science》 SCIE CSCD 2024年第6期1904-1915,共12页
For the basins with debris flow development,its channel terrain exhibits a tortuous shape,which significantly restricts the movement of debris flows and leads to severe erosion effects on the concave bank.Therefore,th... For the basins with debris flow development,its channel terrain exhibits a tortuous shape,which significantly restricts the movement of debris flows and leads to severe erosion effects on the concave bank.Therefore,this study aims to analyze the shear force of debris flows within the bend channel.We established the relationship between the shear force and bend curvature through laboratory experiments.Under the long-term erosion by debris flows,the curvature radius of bends gradually increases,however,when this increasing trend reaches an equilibrium state with the intensity of debris flow discharge,there will be no significant change in curvature radius.In general,the activity pattern and discharges of debris flows would remain relatively stable.Hence,we can infer the magnitude of debris flow discharges from the terrain parameters of the bend channel. 展开更多
关键词 Debris flow discharge Erosion effect bend channel Curvature radius
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Fabrication of lightweight 3D interpenetrated NiTi@Mg composite with superior bending properties
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作者 Yu-jing LIU Xiao-chun LIU +4 位作者 Kun-mao LI Xiang WU Sheng-feng ZHOU Wei LI Wen-cai ZHANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第11期3569-3584,共16页
A NiTi@Mg interpenetrating phase composite with high strength and lightweight was prepared by additive manufacturing(AM)and infiltration technology,and the interface bonding,three-point bending properties and cyclic c... A NiTi@Mg interpenetrating phase composite with high strength and lightweight was prepared by additive manufacturing(AM)and infiltration technology,and the interface bonding,three-point bending properties and cyclic compressive properties of NiTi@Mg composites were investigated.The results show that the metallurgically bonded interface is formed at the NiTi/Mg interfaces.The bending strength and compressive strength of the NiTi@Mg composite are 2.5 and 1.7 times higher than those of the NiTi scaffold,respectively.During the bending deformation process,a large number of dislocations are observed to accumulate in the soft Mg area at the interface.Furthermore,the finite element model showed that the stress accumulation area,where the bending crack is initiated,is located at the interface of NiTi and Mg.The strengthening mechanism of NiTi@Mg composites is attributed to the twinning strengthening of Mg and heterogeneous structure strengthening. 展开更多
关键词 metal composites NiTi@Mg bending properties finite element simulation strengthening mechanism
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