目的:了解上海市素食人群血清ω-3脂肪酸的水平以及与杂食人群的差异。方法:于上海市区招募愿接受调查的成年健康素食者222名及同性别同年龄杂食者222名,通过超高效液相色谱串联质谱方法,测定血清ω-3脂肪酸的含量,包括α-亚麻酸(ALA)...目的:了解上海市素食人群血清ω-3脂肪酸的水平以及与杂食人群的差异。方法:于上海市区招募愿接受调查的成年健康素食者222名及同性别同年龄杂食者222名,通过超高效液相色谱串联质谱方法,测定血清ω-3脂肪酸的含量,包括α-亚麻酸(ALA)、二十二碳六烯酸(DHA)、二十碳五烯酸(EPA)、二十二碳五烯酸(DPA)。用非参数检验比较素食人群与杂食人群血清ω-3脂肪酸含量的差异。结果:虽然素食人群血清ω-3脂肪酸总量(μmol/L)与杂食人群无显著差异(21.26 vs 21.04,P=0.321),但素食人群血清ALA含量(μmol/L)显著高于杂食人群(15.05 vs 11.25,P=0.000),素食人群血清DHA、血清EPA (μmol/L)均显著低于杂食人群[(2.87 vs5.92,P=0.000)、(0.73 vs 0.98,P=0.000)]。素食人群中,全素人群血清DHA含量(μmol/L)显著低于奶蛋素人群(2.17 vs 3.10,P=0.000)。素食时长≥5年人群的血清DHA含量(μmol/L)显著低于素食时长<5年人群(2.59 vs 3.12,P=0.007)。结论:受调查的素食人群血清ω-3脂肪酸总量与杂食人群相当,虽然血清DHA和EPA含量较杂食人群低,但血清ALA含量较杂食人群高。展开更多
Cardiovascular diseases are serious pathologies that affect an increasing number of people. Several preventive measures are generally used, including supplementing of oils in foods. Our objective was to compare the ef...Cardiovascular diseases are serious pathologies that affect an increasing number of people. Several preventive measures are generally used, including supplementing of oils in foods. Our objective was to compare the effects of Tetracarpidum conophorum oil (TC) and corn oil (CO) on serum lipid profiles of normal male rats. 42 Wistar rats were divided into 7 groups. Diets included TC oil (groups TC5, TC10 and TC20) and corn oil (groups CO5, CO10 and CO20) in proportions of 5%, 10% and 20%, with a control group (T). After 5 weeks of feeding, several parameters were measured during and after the study, including body weight, food intake and organ weights (kidney, liver and fat). Lipid profiles (total cholesterol, TG, HDL and LDL), glucose and protein levels were measured in the serum. The increase in body mass was inversely proportional to the amount of oil in the food. The decrease in body mass and adiposomatic index of group TC10 was significant (p < 0.05) compared with the other groups. The lowest glycaemia (64.17 ± 5.14 mg/dl) was noted with the diet containing 20% TC oil. A significant reduction in total cholesterol, LDL fraction and blood triglycerides was observed in the groups supplemented with TC and corn oils compared to controls. Results were also more beneficial for the TC10 group. HDL-cholesterol levels were significantly higher (p < 0.05) in the oil-supplemented groups than in the control group. Castelli’s risk indices decrease significantly (p < 0.05) with increasing oil content for TC. The oils had no impact on blood protein contents. One can conclude that a diet containing 10% crude oil from TC kernels could prevent or alleviate cardiovascular diseases and glycemia.展开更多
文摘目的:了解上海市素食人群血清ω-3脂肪酸的水平以及与杂食人群的差异。方法:于上海市区招募愿接受调查的成年健康素食者222名及同性别同年龄杂食者222名,通过超高效液相色谱串联质谱方法,测定血清ω-3脂肪酸的含量,包括α-亚麻酸(ALA)、二十二碳六烯酸(DHA)、二十碳五烯酸(EPA)、二十二碳五烯酸(DPA)。用非参数检验比较素食人群与杂食人群血清ω-3脂肪酸含量的差异。结果:虽然素食人群血清ω-3脂肪酸总量(μmol/L)与杂食人群无显著差异(21.26 vs 21.04,P=0.321),但素食人群血清ALA含量(μmol/L)显著高于杂食人群(15.05 vs 11.25,P=0.000),素食人群血清DHA、血清EPA (μmol/L)均显著低于杂食人群[(2.87 vs5.92,P=0.000)、(0.73 vs 0.98,P=0.000)]。素食人群中,全素人群血清DHA含量(μmol/L)显著低于奶蛋素人群(2.17 vs 3.10,P=0.000)。素食时长≥5年人群的血清DHA含量(μmol/L)显著低于素食时长<5年人群(2.59 vs 3.12,P=0.007)。结论:受调查的素食人群血清ω-3脂肪酸总量与杂食人群相当,虽然血清DHA和EPA含量较杂食人群低,但血清ALA含量较杂食人群高。
文摘Cardiovascular diseases are serious pathologies that affect an increasing number of people. Several preventive measures are generally used, including supplementing of oils in foods. Our objective was to compare the effects of Tetracarpidum conophorum oil (TC) and corn oil (CO) on serum lipid profiles of normal male rats. 42 Wistar rats were divided into 7 groups. Diets included TC oil (groups TC5, TC10 and TC20) and corn oil (groups CO5, CO10 and CO20) in proportions of 5%, 10% and 20%, with a control group (T). After 5 weeks of feeding, several parameters were measured during and after the study, including body weight, food intake and organ weights (kidney, liver and fat). Lipid profiles (total cholesterol, TG, HDL and LDL), glucose and protein levels were measured in the serum. The increase in body mass was inversely proportional to the amount of oil in the food. The decrease in body mass and adiposomatic index of group TC10 was significant (p < 0.05) compared with the other groups. The lowest glycaemia (64.17 ± 5.14 mg/dl) was noted with the diet containing 20% TC oil. A significant reduction in total cholesterol, LDL fraction and blood triglycerides was observed in the groups supplemented with TC and corn oils compared to controls. Results were also more beneficial for the TC10 group. HDL-cholesterol levels were significantly higher (p < 0.05) in the oil-supplemented groups than in the control group. Castelli’s risk indices decrease significantly (p < 0.05) with increasing oil content for TC. The oils had no impact on blood protein contents. One can conclude that a diet containing 10% crude oil from TC kernels could prevent or alleviate cardiovascular diseases and glycemia.
