The blue swimming crabs Portunus trituberculatus with tea-green and/or purple carapace color have been discovered on the shore of eastern part of China these days, In this paper, 40 color-different crab individuals we...The blue swimming crabs Portunus trituberculatus with tea-green and/or purple carapace color have been discovered on the shore of eastern part of China these days, In this paper, 40 color-different crab individuals were evaluated using 80 RAPD primers. 30 primers were selected using bulk segregation analysis (BSA) and RAPD-PCR analysis. The results showed that the ratio of polymorphic loci was 61.29%, and Nei's gene diversity was 0.375 6, and Shannon's information index was 0.554 5 among purple crab individuals; and the ratio of polymorphic loci was 62.44%, and Nei's gene diversity was 0.3451, and Shannon's information index was 0.5099 among tea-green crab individuals. It was clear that the genetic diversity between purple and tea-green crabs was similar, which indicated close phylogenetic relationships between the purple and tea-green crabs. In addition, two primers (SBS A09 and SBS G16) got specific DNA bands by comparing forty individuals of color-different crab individuals through RAPD-PCR analysis and the following electrophoresis. They indicated close phylogenetic relationships between purple and tea-green crabs.展开更多
Aim and methods The study of three-dimensional quantitative structure-activity relationship (3D-QSAR) of DDPH and its derivatives has been performed using Apex-3D programme. Results The result indicates that substit...Aim and methods The study of three-dimensional quantitative structure-activity relationship (3D-QSAR) of DDPH and its derivatives has been performed using Apex-3D programme. Results The result indicates that substituents of para- and ortho-positions in phenyl ring of aryloxyalkylamine greatly influence the bioactivity. Conclusion The biophore model and 3D-QSAR equation help us not only further understand receptor-ligand interactions, but also design new compounds with better bioactivity.展开更多
Aim and Method Comparative molecular field analysis (CoMFA), a threedimensional quantitative structure-activity relationship (3D-QSAR) method was applied to a novelseries of C-3 substituted 4, 6-dichloioindole-2-carbo...Aim and Method Comparative molecular field analysis (CoMFA), a threedimensional quantitative structure-activity relationship (3D-QSAR) method was applied to a novelseries of C-3 substituted 4, 6-dichloioindole-2-carboxylic acids to study the relationship betweentheir structure and the affinity for the glycine site of the NMDA receptor. Result Hie coefficientsof cross-validation q^2 and non cross-validation r^2 for the model established by the study are0.744 and 0.993, respectively, the value of variance ratio F is 261.343, and standard error estimate(SE) is 0.039. Conclusion These values indicate that the CoMFA model may have a good prediction forthe activity of C-3 substituted 4, 6-dichloroin-dole-2-carboxylic acids. As a consequence, thepredicted activity values of new designed compounds supports our conclusion from the model.展开更多
The first step to defining the rights,responsibilities and interests of stakeholders and constructing a compensation mechanism is to identify the stakeholders and clarify their mutual relationships.Nature reserves are...The first step to defining the rights,responsibilities and interests of stakeholders and constructing a compensation mechanism is to identify the stakeholders and clarify their mutual relationships.Nature reserves are complex ecosystems involving nature,the economy and society.There exists a conflict between the public welfare benefits of ecological conservation and the private gains to be realized from social and economic development.There also exist in a nature reserve complex relationships among stakeholders,involving the utilization of ecological resources,ecological conservation and ecological-economic interests.The introduction of tourism brings substantial changes to the existing stakeholder benefit structure in a nature reserve.The implementation of tourism ecological compensation(tourism payment for ecological service)is a process for redefining the distribution of rights,responsibilities and profits among stakeholders and it is also an essential way to balance the interests of the stakeholders.This paper uses a case study of Sanya Coral Reef National Nature Reserve in China to examine the characteristics of stakeholders and analyze their interests.According to the method for defining basic attributes proposed by Mitchel and other scholars,in cases of tourism ecological compensation,stakeholders can be classified as definitive stakeholders,expectant stakeholders and latent stakeholders.This paper applies these classifications and then analyzes the relationships between the rights and responsibilities of these stakeholders and how these change after the implementation of compensation.Additionally,based on the impact compensation has on different stakeholders,changes in the relationships can be analyzed and the structure of the stakeholders can be modelled.This case study of the Sanya Coral Reef National Nature Reserve illustrates the operationalization of a new mechanism for tourism ecological compensation.The paper illustrates a method for coordinating the relationships among the stakeholders involved with this national-level nature reserve.展开更多
Intergroup conflicts occupy a special place in the interaction of social groups and of necessity form the basic building blocks for the integration of previously fragmented groups. The Western Niger delta obviously ha...Intergroup conflicts occupy a special place in the interaction of social groups and of necessity form the basic building blocks for the integration of previously fragmented groups. The Western Niger delta obviously has since been a theatre of socio-political conflicts. Viewed from the contemporary clime, there is a lacuna in the formulation of theories and concepts in understanding and explaining the nature and pattern of intergroup relations in the region from the pre-colonial period. This work therefore attempts an exploratory analysis of some theories and concepts of intergroup relations in the Western Niger Delta of Nigeria using the historical approach with the use of secondary source materials. The paper concludes that the relation among the diverse ethnic groups in Nigeria, especially the Western Niger Delta, may not have been as intense, or as hostile as it has become since the attainment of independence in 1960. This paper no doubt is essential for the understanding and tackling of the problem of intergroup relations and conflict in the region in particular and Nigeria at large.展开更多
基金supported by the grant of the Key Project in the National Science & Technology Pillar Program in the Eleventh Five-year Plan Period (No. 2006BAD09A01)
文摘The blue swimming crabs Portunus trituberculatus with tea-green and/or purple carapace color have been discovered on the shore of eastern part of China these days, In this paper, 40 color-different crab individuals were evaluated using 80 RAPD primers. 30 primers were selected using bulk segregation analysis (BSA) and RAPD-PCR analysis. The results showed that the ratio of polymorphic loci was 61.29%, and Nei's gene diversity was 0.375 6, and Shannon's information index was 0.554 5 among purple crab individuals; and the ratio of polymorphic loci was 62.44%, and Nei's gene diversity was 0.3451, and Shannon's information index was 0.5099 among tea-green crab individuals. It was clear that the genetic diversity between purple and tea-green crabs was similar, which indicated close phylogenetic relationships between the purple and tea-green crabs. In addition, two primers (SBS A09 and SBS G16) got specific DNA bands by comparing forty individuals of color-different crab individuals through RAPD-PCR analysis and the following electrophoresis. They indicated close phylogenetic relationships between purple and tea-green crabs.
文摘Aim and methods The study of three-dimensional quantitative structure-activity relationship (3D-QSAR) of DDPH and its derivatives has been performed using Apex-3D programme. Results The result indicates that substituents of para- and ortho-positions in phenyl ring of aryloxyalkylamine greatly influence the bioactivity. Conclusion The biophore model and 3D-QSAR equation help us not only further understand receptor-ligand interactions, but also design new compounds with better bioactivity.
文摘Aim and Method Comparative molecular field analysis (CoMFA), a threedimensional quantitative structure-activity relationship (3D-QSAR) method was applied to a novelseries of C-3 substituted 4, 6-dichloioindole-2-carboxylic acids to study the relationship betweentheir structure and the affinity for the glycine site of the NMDA receptor. Result Hie coefficientsof cross-validation q^2 and non cross-validation r^2 for the model established by the study are0.744 and 0.993, respectively, the value of variance ratio F is 261.343, and standard error estimate(SE) is 0.039. Conclusion These values indicate that the CoMFA model may have a good prediction forthe activity of C-3 substituted 4, 6-dichloroin-dole-2-carboxylic acids. As a consequence, thepredicted activity values of new designed compounds supports our conclusion from the model.
基金The National Natural Science Foundation of China(4166111141361107+1 种基金41561111)the Natural Science Foundation of Hainan Province(413125)
文摘The first step to defining the rights,responsibilities and interests of stakeholders and constructing a compensation mechanism is to identify the stakeholders and clarify their mutual relationships.Nature reserves are complex ecosystems involving nature,the economy and society.There exists a conflict between the public welfare benefits of ecological conservation and the private gains to be realized from social and economic development.There also exist in a nature reserve complex relationships among stakeholders,involving the utilization of ecological resources,ecological conservation and ecological-economic interests.The introduction of tourism brings substantial changes to the existing stakeholder benefit structure in a nature reserve.The implementation of tourism ecological compensation(tourism payment for ecological service)is a process for redefining the distribution of rights,responsibilities and profits among stakeholders and it is also an essential way to balance the interests of the stakeholders.This paper uses a case study of Sanya Coral Reef National Nature Reserve in China to examine the characteristics of stakeholders and analyze their interests.According to the method for defining basic attributes proposed by Mitchel and other scholars,in cases of tourism ecological compensation,stakeholders can be classified as definitive stakeholders,expectant stakeholders and latent stakeholders.This paper applies these classifications and then analyzes the relationships between the rights and responsibilities of these stakeholders and how these change after the implementation of compensation.Additionally,based on the impact compensation has on different stakeholders,changes in the relationships can be analyzed and the structure of the stakeholders can be modelled.This case study of the Sanya Coral Reef National Nature Reserve illustrates the operationalization of a new mechanism for tourism ecological compensation.The paper illustrates a method for coordinating the relationships among the stakeholders involved with this national-level nature reserve.
文摘Intergroup conflicts occupy a special place in the interaction of social groups and of necessity form the basic building blocks for the integration of previously fragmented groups. The Western Niger delta obviously has since been a theatre of socio-political conflicts. Viewed from the contemporary clime, there is a lacuna in the formulation of theories and concepts in understanding and explaining the nature and pattern of intergroup relations in the region from the pre-colonial period. This work therefore attempts an exploratory analysis of some theories and concepts of intergroup relations in the Western Niger Delta of Nigeria using the historical approach with the use of secondary source materials. The paper concludes that the relation among the diverse ethnic groups in Nigeria, especially the Western Niger Delta, may not have been as intense, or as hostile as it has become since the attainment of independence in 1960. This paper no doubt is essential for the understanding and tackling of the problem of intergroup relations and conflict in the region in particular and Nigeria at large.