型号产品地面供气设备“三化”研究

根据装备“三化”的指导思想和“三化”的理论方法,结合型号产品地面供气设备的研制、生产和使用情况,对供气设备的现状进行了分析,提出了相应的“三化”方案,并对具体方案进行了阐述。

Migration of Infiltrated NH_4 and NO_3 in a Soil and Groundwater System Simulated by a Soil Tank

The infiltration of water contaminants into soil and groundwater systems can greatly affect the quality of groundwater. A laboratory-designed large soil tank with periodic and continuous infiltration models, respectively, was used to simulate the migration of the contaminants NH4 and NO3 in a soil and groundwater system, including unsaturated and saturated zones. The unsaturated soil zone had a significant effect on removing NH4 and NO3 infiltrated from the surface water. The patterns of breakthrough curves of NH4 and NO3 in the unsaturated zone were related to the infiltration time. A short infiltration time resulted in a single sharp peak in the breakthrough curve, while a long infiltration time led to a plateau curve. When NH4 and NO3 migrated from the unsaturated zone to the saturated zone, an interracial retardation was formed, resulting in an increased contaminant concentration on the interface. Under the influence of horizontal groundwater movement, the infiltrated contaminants formed a contamination-prone area downstream. As the contaminants migrated downstream, their concentrations were significantly reduced. Under the same infiltration concentration, the concentration of NO3 was greater than that of NH4 at every corresponding cross-section in the soil and groundwater tank, suggesting that the removal efficiency of NH4 was greater than that of NO3 in the soil and groundwater system.

Development and Commercial Application of Third Generation Resid Hydrotreating Catalysts

Based on the mechanism of resid hydrotreating reaction by coordinating the catalyst activity and stability, the diffusion mechanism and catalyst reactivity, the cost and catalyst performance, and the production and application requirements, the third-generation series catalysts for residue hydrotreating have been developed by Research Institute of Petroleum Processing, SINOPEC. The new series RHT catalysts possess higher activity for HDS, HDM and HDCCR performance as well as longer run length. The commercial results for application of these catalysts have demonstrated that the new catalyst system performs better than the reference ones.

Docking and 3D-QSAR studies of N-benzyl isatin oximes as JNK3 inhibitors

The c-Jun N-terminal kinase （JNK） is involved in a variety of important cellular processes and aberrant JNK activity is associated with many human diseases.The ligand-based and receptor-based alignment rules were used to build 3D-QSAR models for a series of N-benzyl isatin oximes JNK inhibitors. The best models were obtained for the receptor-based alignment with CoMSIA combining steric （S）, electrostatic （E）, and hydrogen bond donor （D） and hydrogen bond acceptor （A） fields （q2 = 0.759, r2 = 0.966, r2 pred = 0.703）. Based on the contour maps of RB CoMSIA model, some key structural factors responsible for inhibitory activity were investigated. Large groups at N-substituent or R6 position are preferred to interact with hydrophobic residues Ile70, Asp150, Ala151, Asn152 and Ser193. Electron-donating or hydrogen bond donor groups on the isatin ring would form polar and hydrogen bond with the negative-charged residue Glu147. In addition, electron-withdrawing groups or hydrogen bond acceptor group near the N-substituent would enhance inhibitory activity. The results are in good accordance and complementary to each other. The developed models could provide guidance in the rational design of more potent and selective JNK inhibitors.

Low-frequency fluctuation amplitude analysis of resting-state fMRI for functional brain response differences between acupuncture and moxibustion at Zusanli(ST 36) in patient with functional dyspepsia

Objective： To compare and analyze functional brain response characteristics by applying acupuncture or moxibustion to Zusanli（ST 36） in patients with functional dyspepsia（FD） and investigate the differences of central action mechanism resulting from acupuncture or moxibustion.Methods： A total of eligible 24 FD cases were divided into two blood-oxygen-level dependent（BOLD） sequences for functional magnetic resonance imaging（fMRI） scan. The amplitude of low frequency fluctuation（ALFF） analyses were conducted on the data of location phase, structure phase, resting state before acupuncture/moxibustion, working state during acupuncture/moxibustion and resting state after acupuncture/moxibustion using Data Processing Assistant for Resting-State fMRI（DPARSF） software.Results： Acupuncture and moxibustion produced significant differences in functional brain response. The working state during acupuncture/moxibustion mainly decreased ALFF values in the right supramarginal gyrus, right superior parietal lobule, right frontal gyrus, upper right occipital lobe, right precuneus and right cingulate gyrus. At the same time, it increased ALFF values in the left cerebellum, right caudate nucleus, right cerebellum and left inferior gyrus. The differences during the resting state after acupuncture/moxibustion were significantly smaller than the working state in intensity and size. It mainly resulted in decrease in ALFF values in the right postcentral gyrus and right supramarginal gyrus and increase in ALFF values in the left precuneus, orbital part of inferior frontal gyrus and right cerebellar peduncles.Conclusion： Needling and moxibustion at Zusanli（ST 36） can produce significant differences in immediate functional brain response.

A method of shadow puppet figure modeling and animation

To promote the development of the intangible cultural heritage of the world, shadow play, many studies have focused on shadow puppet modeling and interaction. Most of the shadow puppet figures are still imaginary,spread by ancients, or carved and painted by shadow puppet artists, without consideration of real dimensions or the appearance of human bodies. This study proposes an algorithm to transform 3D human models to 2D puppet figures for shadow puppets, including automatic location of feature points, automatic segmentation of 3D models, automatic extraction of 2D contours, automatic clothes matching, and animation. Experiment proves that more realistic and attractive figures and animations of the shadow puppet can be generated in real time with this algorithm.