Objective To explore prenatal ultrasonic characteristics of fetal Currarino syndrome(CS)and methods for prenatal diagnosis of CS.Methods Two fetuses with CS confirmed by genetic examination were retrospectively analyz...Objective To explore prenatal ultrasonic characteristics of fetal Currarino syndrome(CS)and methods for prenatal diagnosis of CS.Methods Two fetuses with CS confirmed by genetic examination were retrospectively analyzed,while 6 CS fetuses with complete prenatal ultrasonic data in literature were reviewed.Prenatal ultrasonic characteristics of CS fetuses and the method for prenatal diagnosis of CS were discussed.Results Among 8 CS fetuses diagnosed with prenatal ultrasound,4 were female singletons with a clear family history of CS,and MNX 1 gene mutation was found in 1 fetus.The other 4 fetuses were 2 pairs of male monochorionic twins,all with MNX 1 gene mutation.Among 8 CS fetuses,complete triad(sacral agenesis abnormalities,anorectal malformation and presacral mass)were displayed only in 2 fetuses,while all 8 had sacral agenesis abnormalities and 6(6/8,75.00%)were detected with prenatal ultrasound,6 had low location of conus medullaris and 2(2/6,33.33%)detected with prenatal ultrasound.Conclusion Prenatal ultrasound was the first choice for non-invasive diagnosis of fetal CS.When one of sacral agenesis abnormalities,anorectal malformation and presacral mass was found with prenatal ultrasound,the possibility of CS should be considered,and fetal MRI,genetic examination and prenatal genetic counselling should be recommended if necessary.展开更多
This paper refers to an integrated mCCHP （micro-combined cooling heat and power） systems dedicated for isolated residents with energetic independence. The only energy sources are wood pellet and solar energy. The pr...This paper refers to an integrated mCCHP （micro-combined cooling heat and power） systems dedicated for isolated residents with energetic independence. The only energy sources are wood pellet and solar energy. The proposed trigeneration system is based on mCHP （micro-combined heat and power） unit with Stirling engine, photovoltaic panels, thermal solar collector and pellet boiler. The proposed mCCHP system utilizes the exceeding amount of heat in the summer for producing the necessary cooling. A residential building with known energy consumption is determined load curves that must be covered by mCCHP system. The paper analyzes four structures of trigeneration systems with thermal activation chiller and two structures of trigeneration systems with mechanical compression chiller. Performance indicators are determined based on energy balance equations for each variant. It compares the performances and establishes the best option.展开更多
文摘Objective To explore prenatal ultrasonic characteristics of fetal Currarino syndrome(CS)and methods for prenatal diagnosis of CS.Methods Two fetuses with CS confirmed by genetic examination were retrospectively analyzed,while 6 CS fetuses with complete prenatal ultrasonic data in literature were reviewed.Prenatal ultrasonic characteristics of CS fetuses and the method for prenatal diagnosis of CS were discussed.Results Among 8 CS fetuses diagnosed with prenatal ultrasound,4 were female singletons with a clear family history of CS,and MNX 1 gene mutation was found in 1 fetus.The other 4 fetuses were 2 pairs of male monochorionic twins,all with MNX 1 gene mutation.Among 8 CS fetuses,complete triad(sacral agenesis abnormalities,anorectal malformation and presacral mass)were displayed only in 2 fetuses,while all 8 had sacral agenesis abnormalities and 6(6/8,75.00%)were detected with prenatal ultrasound,6 had low location of conus medullaris and 2(2/6,33.33%)detected with prenatal ultrasound.Conclusion Prenatal ultrasound was the first choice for non-invasive diagnosis of fetal CS.When one of sacral agenesis abnormalities,anorectal malformation and presacral mass was found with prenatal ultrasound,the possibility of CS should be considered,and fetal MRI,genetic examination and prenatal genetic counselling should be recommended if necessary.
文摘This paper refers to an integrated mCCHP （micro-combined cooling heat and power） systems dedicated for isolated residents with energetic independence. The only energy sources are wood pellet and solar energy. The proposed trigeneration system is based on mCHP （micro-combined heat and power） unit with Stirling engine, photovoltaic panels, thermal solar collector and pellet boiler. The proposed mCCHP system utilizes the exceeding amount of heat in the summer for producing the necessary cooling. A residential building with known energy consumption is determined load curves that must be covered by mCCHP system. The paper analyzes four structures of trigeneration systems with thermal activation chiller and two structures of trigeneration systems with mechanical compression chiller. Performance indicators are determined based on energy balance equations for each variant. It compares the performances and establishes the best option.
