Occult hepatitis B infection(OBI) is characterized by hepatitis B virus(HBV) DNA in serum in the absence of hepatitis B surface antigen(HBsAg) presenting HBsAg-negative and anti-HBc positive serological patterns.Occul...Occult hepatitis B infection(OBI) is characterized by hepatitis B virus(HBV) DNA in serum in the absence of hepatitis B surface antigen(HBsAg) presenting HBsAg-negative and anti-HBc positive serological patterns.Occult HBV status is associated in some cases with mutant viruses undetectable by HBsAg assays;but more frequently it is due to a strong suppression of viral replication and gene expression.OBI is an entity with world-wide diffusion.The failure to detect HBsAg,despite the persistence of the viral DNA,is due in most cases to the strong suppression of viral replication and gene expression that characterizes this"occult"HBV infection;although the mechanisms responsible for suppression of HBV are not well understood.The majority of OBI cases are secondary to overt HBV infection and represent a residual low viremia level suppressed by a strong immune response together with histological derangements which occurred during acute or chronic HBV infection.Much evidence suggests that it can favour the progression of liver fibrosis and the development of hepatocellular carcinoma.展开更多
On-line monitoring and fault diagnosis of chemical process is extremely important for operation safety and product quality. Principal component analysis (PCA) has been widely used in multivariate statistical process m...On-line monitoring and fault diagnosis of chemical process is extremely important for operation safety and product quality. Principal component analysis (PCA) has been widely used in multivariate statistical process monitoring for its ability to reduce processes dimensions. PCA and other statistical techniques, however, have difficulties in differentiating faults correctly in complex chemical process. Support vector machine (SVM) is a novel approach based on statistical learning theory, which has emerged for feature identification and classification. In this paper, an integrated method is applied for process monitoring and fault diagnosis, which combines PCA for fault feature extraction and multiple SVMs for identification of different fault sources. This approach is verified and illustrated on the Tennessee Eastman benchmark process as a case study. Results show that the proposed PCA-SVMs method has good diagnosis capability and overall diagnosis correctness rate.展开更多
Based on analysis of schedule setting and player performance of the sixth CCTV host contest, we discuss the selection contest idea and point out that the good quality of thinking is the core host of outstanding qualit...Based on analysis of schedule setting and player performance of the sixth CCTV host contest, we discuss the selection contest idea and point out that the good quality of thinking is the core host of outstanding quality, and the thinking quality of excellent host has three dimensions (depth of thinking, thinking, breadth and sensitivity thinking). Hosts should made efforts to nurture their spirituality and personality under the guidance of this scale.展开更多
The introduction of the ICTs (Information and Communication Technologies) in education has set a new paradigm in knowledge acquisition. The Internet, overhead projectors and interactive boards, presentation and anim...The introduction of the ICTs (Information and Communication Technologies) in education has set a new paradigm in knowledge acquisition. The Internet, overhead projectors and interactive boards, presentation and animation software, and online databases are only some resources that teachers use in order to present information in a more dynamic, immediate, and stunning way, transforming and revitalizing the teaching-learning process. The ICTs have been established in the university classroom and nowadays, they have become an essential part in this teaching-learning process. Lecturers make use of them in the same proportion as they make of traditional materials. At the same time, students have to be acquainted with these new technologies and they also have to be able to deal with them. The objective of this paper is twofold: On the one hand, we study and show how our students make use of the technologies when they have to face their oral presentations in the subject Advanced English: Professional Settings (English Studies Degree at Universitat Jaume I in Castellen, Spain). It is acknowledged that visual aids can be helpful to support a speech, but we want to analyze if the visual aids are successfully applied, how and to which extent. On the other hand, we want to make out the opinions of their classmates about the use of these graphical resources (students fill in a questionnaire about the effectiveness of the visual aids in their classmates' presentations and how they would improve them). Results demonstrate that not only teachers make advantage of the new technological resources, we show, based on the students' oral presentations and their peer-reviews, that also our university students are increasingly aware of the advantage and importance of the ICTs in the classroom.展开更多
To make up the poor quality defects of traditional control methods and meet the growing requirements of accuracy for strip crown,an optimized model based on support vector machine(SVM)is put forward firstly to enhance...To make up the poor quality defects of traditional control methods and meet the growing requirements of accuracy for strip crown,an optimized model based on support vector machine(SVM)is put forward firstly to enhance the quality of product in hot strip rolling.Meanwhile,for enriching data information and ensuring data quality,experimental data were collected from a hot-rolled plant to set up prediction models,as well as the prediction performance of models was evaluated by calculating multiple indicators.Furthermore,the traditional SVM model and the combined prediction models with particle swarm optimization(PSO)algorithm and the principal component analysis combined with cuckoo search(PCA-CS)optimization strategies are presented to make a comparison.Besides,the prediction performance comparisons of the three models are discussed.Finally,the experimental results revealed that the PCA-CS-SVM model has the highest prediction accuracy and the fastest convergence speed.Furthermore,the root mean squared error(RMSE)of PCA-CS-SVM model is 2.04μm,and 98.15%of prediction data have an absolute error of less than 4.5μm.Especially,the results also proved that PCA-CS-SVM model not only satisfies precision requirement but also has certain guiding significance for the actual production of hot strip rolling.展开更多
The calls for the employment demand are making a change to the rigid, backward teaching method. In this paper, the "three- dimensional teaching" as a very scientific, flexible, and efficient classroom teaching model...The calls for the employment demand are making a change to the rigid, backward teaching method. In this paper, the "three- dimensional teaching" as a very scientific, flexible, and efficient classroom teaching model currently is mainly discussed. Meanwhile, the dynamic internal composition of the "three-dimensional teaching" is mainly introduced from its three stages and three principles, and also the three-dimensional teaching reform plan is supported and promoted based on two advantages.展开更多
"EQ" has become one of the modem professional qualities; it is a capacity to deal with emotions. In the current work, the pressure of living is low and the ability to make personal frustration TV presenter faced sev..."EQ" has become one of the modem professional qualities; it is a capacity to deal with emotions. In the current work, the pressure of living is low and the ability to make personal frustration TV presenter faced severe psychological crisis. "EQ" on the TV show host has important implications; they focus on "emotional intelligence" training TV show host; the "EQ" Test selection criteria included the host, it is to improve the professional competence of TV presenter quality.展开更多
Background P-wave dispersion (PWD), a measure of heterogeneity of atrial refractoriness, is defined as the difference between the maximum and minimum P-wave duration. In patients with severe aortic stenosis (AS), ...Background P-wave dispersion (PWD), a measure of heterogeneity of atrial refractoriness, is defined as the difference between the maximum and minimum P-wave duration. In patients with severe aortic stenosis (AS), P-wave duration and PWD were shown to be increased, indicating atrial electrical remodeling. However, the effect of transcatheter aortic valve replacement (TAVR) on P-wave morphology has not been established yet. The aim of this study is to assess the short and long-term effects of TAVR with two types of bioprosthetic valves on P-wave duration and PWD in association with left atrial (LA) size. Methods Fifty-two (36 female) eligible patients in sinus rhythm who underwent transfemoral TAVR between June 01, 2012 and July 31, 2014 with either a Medtronic CoreValve (MCV) (n = 32) or an Edwards SAPIEN XT Valve (n = 20) were enrolled. Standard 12-lead electrocardiogram and echocardiographic evaluations were per- formed pre-procedurally, post-TAVR day one and 6 months post-TAVR. P-wave duration and PWD were measured and correlation analyses with echocardiographic variables were performed. Results P-wave duration and PWD were significantly decreased on post-TAVR day one (P 〈 0.05). They continued to decrease during the six month follow-up period, but were not significantly different from short-term values (P 〉 0.05). The decrease of LA diameter was found significant at the sixth-months of follow-up (P 〈 0.05). These changes were independent from the types of bioprosthetic valves implanted (P 〉 0.05). A positive correlation was detected between minimum P-wave duration and maximum aortic valve gradients at post-TAVR day one (r = 0.297, P = 0.032). Conclusions P-wave duration and PWD were significantly reduced early after TAVR indicating early reverse atrial electrical remodeling. Moreover, structural reverse remodeling of atrium was detected at the 6-months of follow-up. The effects of two types of bioprosthetic valves on atrial remodeling were similar.展开更多
When it comes to the afterlife, Seventh-day Adventists advocate "soul sleep" condition, in which the dead person is in some sort of suspended state until the final judgment. On the other hand, many Evangelical Chris...When it comes to the afterlife, Seventh-day Adventists advocate "soul sleep" condition, in which the dead person is in some sort of suspended state until the final judgment. On the other hand, many Evangelical Christians believe that the dead go directly to Heaven to be with the Lord. But in Roman Catholicism, purgatory is considered as the place where most dead believers expiate their remaining sins before entering the visible presence of God. This doctrine has been criticized extensively both by Catholics and Evangelicals in spite of its massive defence by the Holy office. Several alternative views about the resurrection of the dead have been propounded by some twentieth-century Protestants and some notable Catholic theologians. Although the doctrine of purgatory has been approved and reaffirmed by several Church councils, the questions that still remain are: Is the doctrine of purgatory biblically justifiable? Does the work of salvation extend beyond the grave? This study attempts to find answers to these questions. The study therefore surveys the doctrine of purgatory in the light of the biblical teachings about death. The second section surveys the background to the doctrine with reference to Judaism, the Apocrypha, the New Testament, the Church Fathers, and Church Councils. The third section looks at the nature of purgatory, the duration and the nature of the punishment meted out to those who go to purgatory and how souls are released from purgatory. The fourth section also examines the biblical teaching on death. The study concludes that the doctrine of purgatory is based on tradition rather than the Bible. The Bible emphasizes the finality of one's destiny in this life rather than after this life.展开更多
According to the development trend in China' s radio and television industry, the requirements of the media for broadcasters and hosts are totally different from before, and they differ from each other. Good appearan...According to the development trend in China' s radio and television industry, the requirements of the media for broadcasters and hosts are totally different from before, and they differ from each other. Good appearance, elegant temperament and pleasant voice are no longer the sole criteria for being employed. This paper analyzes the problems with the education of broadcasting and hosting majors in China' s universities and proposes strategies and suggestions on this, so as to offer a guideline for its future development.展开更多
文摘Occult hepatitis B infection(OBI) is characterized by hepatitis B virus(HBV) DNA in serum in the absence of hepatitis B surface antigen(HBsAg) presenting HBsAg-negative and anti-HBc positive serological patterns.Occult HBV status is associated in some cases with mutant viruses undetectable by HBsAg assays;but more frequently it is due to a strong suppression of viral replication and gene expression.OBI is an entity with world-wide diffusion.The failure to detect HBsAg,despite the persistence of the viral DNA,is due in most cases to the strong suppression of viral replication and gene expression that characterizes this"occult"HBV infection;although the mechanisms responsible for suppression of HBV are not well understood.The majority of OBI cases are secondary to overt HBV infection and represent a residual low viremia level suppressed by a strong immune response together with histological derangements which occurred during acute or chronic HBV infection.Much evidence suggests that it can favour the progression of liver fibrosis and the development of hepatocellular carcinoma.
文摘On-line monitoring and fault diagnosis of chemical process is extremely important for operation safety and product quality. Principal component analysis (PCA) has been widely used in multivariate statistical process monitoring for its ability to reduce processes dimensions. PCA and other statistical techniques, however, have difficulties in differentiating faults correctly in complex chemical process. Support vector machine (SVM) is a novel approach based on statistical learning theory, which has emerged for feature identification and classification. In this paper, an integrated method is applied for process monitoring and fault diagnosis, which combines PCA for fault feature extraction and multiple SVMs for identification of different fault sources. This approach is verified and illustrated on the Tennessee Eastman benchmark process as a case study. Results show that the proposed PCA-SVMs method has good diagnosis capability and overall diagnosis correctness rate.
文摘Based on analysis of schedule setting and player performance of the sixth CCTV host contest, we discuss the selection contest idea and point out that the good quality of thinking is the core host of outstanding quality, and the thinking quality of excellent host has three dimensions (depth of thinking, thinking, breadth and sensitivity thinking). Hosts should made efforts to nurture their spirituality and personality under the guidance of this scale.
文摘The introduction of the ICTs (Information and Communication Technologies) in education has set a new paradigm in knowledge acquisition. The Internet, overhead projectors and interactive boards, presentation and animation software, and online databases are only some resources that teachers use in order to present information in a more dynamic, immediate, and stunning way, transforming and revitalizing the teaching-learning process. The ICTs have been established in the university classroom and nowadays, they have become an essential part in this teaching-learning process. Lecturers make use of them in the same proportion as they make of traditional materials. At the same time, students have to be acquainted with these new technologies and they also have to be able to deal with them. The objective of this paper is twofold: On the one hand, we study and show how our students make use of the technologies when they have to face their oral presentations in the subject Advanced English: Professional Settings (English Studies Degree at Universitat Jaume I in Castellen, Spain). It is acknowledged that visual aids can be helpful to support a speech, but we want to analyze if the visual aids are successfully applied, how and to which extent. On the other hand, we want to make out the opinions of their classmates about the use of these graphical resources (students fill in a questionnaire about the effectiveness of the visual aids in their classmates' presentations and how they would improve them). Results demonstrate that not only teachers make advantage of the new technological resources, we show, based on the students' oral presentations and their peer-reviews, that also our university students are increasingly aware of the advantage and importance of the ICTs in the classroom.
基金Project(52005358)supported by the National Natural Science Foundation of ChinaProject(2018YFB1307902)supported by the National Key R&D Program of China+1 种基金Project(201901D111243)supported by the Natural Science Foundation of Shanxi Province,ChinaProject(2019-KF-25-05)supported by the Natural Science Foundation of Liaoning Province,China。
文摘To make up the poor quality defects of traditional control methods and meet the growing requirements of accuracy for strip crown,an optimized model based on support vector machine(SVM)is put forward firstly to enhance the quality of product in hot strip rolling.Meanwhile,for enriching data information and ensuring data quality,experimental data were collected from a hot-rolled plant to set up prediction models,as well as the prediction performance of models was evaluated by calculating multiple indicators.Furthermore,the traditional SVM model and the combined prediction models with particle swarm optimization(PSO)algorithm and the principal component analysis combined with cuckoo search(PCA-CS)optimization strategies are presented to make a comparison.Besides,the prediction performance comparisons of the three models are discussed.Finally,the experimental results revealed that the PCA-CS-SVM model has the highest prediction accuracy and the fastest convergence speed.Furthermore,the root mean squared error(RMSE)of PCA-CS-SVM model is 2.04μm,and 98.15%of prediction data have an absolute error of less than 4.5μm.Especially,the results also proved that PCA-CS-SVM model not only satisfies precision requirement but also has certain guiding significance for the actual production of hot strip rolling.
文摘The calls for the employment demand are making a change to the rigid, backward teaching method. In this paper, the "three- dimensional teaching" as a very scientific, flexible, and efficient classroom teaching model currently is mainly discussed. Meanwhile, the dynamic internal composition of the "three-dimensional teaching" is mainly introduced from its three stages and three principles, and also the three-dimensional teaching reform plan is supported and promoted based on two advantages.
文摘"EQ" has become one of the modem professional qualities; it is a capacity to deal with emotions. In the current work, the pressure of living is low and the ability to make personal frustration TV presenter faced severe psychological crisis. "EQ" on the TV show host has important implications; they focus on "emotional intelligence" training TV show host; the "EQ" Test selection criteria included the host, it is to improve the professional competence of TV presenter quality.
文摘Background P-wave dispersion (PWD), a measure of heterogeneity of atrial refractoriness, is defined as the difference between the maximum and minimum P-wave duration. In patients with severe aortic stenosis (AS), P-wave duration and PWD were shown to be increased, indicating atrial electrical remodeling. However, the effect of transcatheter aortic valve replacement (TAVR) on P-wave morphology has not been established yet. The aim of this study is to assess the short and long-term effects of TAVR with two types of bioprosthetic valves on P-wave duration and PWD in association with left atrial (LA) size. Methods Fifty-two (36 female) eligible patients in sinus rhythm who underwent transfemoral TAVR between June 01, 2012 and July 31, 2014 with either a Medtronic CoreValve (MCV) (n = 32) or an Edwards SAPIEN XT Valve (n = 20) were enrolled. Standard 12-lead electrocardiogram and echocardiographic evaluations were per- formed pre-procedurally, post-TAVR day one and 6 months post-TAVR. P-wave duration and PWD were measured and correlation analyses with echocardiographic variables were performed. Results P-wave duration and PWD were significantly decreased on post-TAVR day one (P 〈 0.05). They continued to decrease during the six month follow-up period, but were not significantly different from short-term values (P 〉 0.05). The decrease of LA diameter was found significant at the sixth-months of follow-up (P 〈 0.05). These changes were independent from the types of bioprosthetic valves implanted (P 〉 0.05). A positive correlation was detected between minimum P-wave duration and maximum aortic valve gradients at post-TAVR day one (r = 0.297, P = 0.032). Conclusions P-wave duration and PWD were significantly reduced early after TAVR indicating early reverse atrial electrical remodeling. Moreover, structural reverse remodeling of atrium was detected at the 6-months of follow-up. The effects of two types of bioprosthetic valves on atrial remodeling were similar.
文摘When it comes to the afterlife, Seventh-day Adventists advocate "soul sleep" condition, in which the dead person is in some sort of suspended state until the final judgment. On the other hand, many Evangelical Christians believe that the dead go directly to Heaven to be with the Lord. But in Roman Catholicism, purgatory is considered as the place where most dead believers expiate their remaining sins before entering the visible presence of God. This doctrine has been criticized extensively both by Catholics and Evangelicals in spite of its massive defence by the Holy office. Several alternative views about the resurrection of the dead have been propounded by some twentieth-century Protestants and some notable Catholic theologians. Although the doctrine of purgatory has been approved and reaffirmed by several Church councils, the questions that still remain are: Is the doctrine of purgatory biblically justifiable? Does the work of salvation extend beyond the grave? This study attempts to find answers to these questions. The study therefore surveys the doctrine of purgatory in the light of the biblical teachings about death. The second section surveys the background to the doctrine with reference to Judaism, the Apocrypha, the New Testament, the Church Fathers, and Church Councils. The third section looks at the nature of purgatory, the duration and the nature of the punishment meted out to those who go to purgatory and how souls are released from purgatory. The fourth section also examines the biblical teaching on death. The study concludes that the doctrine of purgatory is based on tradition rather than the Bible. The Bible emphasizes the finality of one's destiny in this life rather than after this life.
文摘According to the development trend in China' s radio and television industry, the requirements of the media for broadcasters and hosts are totally different from before, and they differ from each other. Good appearance, elegant temperament and pleasant voice are no longer the sole criteria for being employed. This paper analyzes the problems with the education of broadcasting and hosting majors in China' s universities and proposes strategies and suggestions on this, so as to offer a guideline for its future development.