With the aid of commercial finite element analysis software package ANSYS,investigations are made on the contributions of main components to stiffness of the main module for parallel machine tools,and it is found that...With the aid of commercial finite element analysis software package ANSYS,investigations are made on the contributions of main components to stiffness of the main module for parallel machine tools,and it is found that the frame is the main contributor.Then,influences of constraints,strut length and working ways of the main module have also been investigated.It can be concluded that when one of the main planes of the frame without linear drive unit is constrained,the largest whole stiffness can be acquired.And,the stiffness is much better when the main module is used in a vertical machine tool instead of a horizontal one.Finally,the principle of stiffness variation is summarized when the mobile platform reaches various positions within its working space and when various loads are applied.These achievements have provided critical instructions for the design of the main module for parallel machine tools.展开更多
AIM To evaluate the safety and efficacy of combined endovascular brachytherapy(EVBT),transarterial chemoembolization(TACE),and sorafenib to treat hepatocellular carcinoma(HCC) patients with main portal vein tumor thro...AIM To evaluate the safety and efficacy of combined endovascular brachytherapy(EVBT),transarterial chemoembolization(TACE),and sorafenib to treat hepatocellular carcinoma(HCC) patients with main portal vein tumor thrombus(MPVTT).METHODS This single-center retrospective study involved 68 patients with unresectable HCC or those who were unfit for liver transplantation and percutaneous frequency ablation according to the BCLC classification. All patients had Child-Pugh classification grade A or B,Eastern Cooperative Oncology Group(ECOG)performance status of 0-2,and MPVTT. The patients received either EVBT with stent placement,TACE,and sorafenib(group A,n = 37),or TACE with sorafenib(group B,n = 31). The time to progression(TTP) and overall survival(OS) were evaluated by propensity score analysis.RESULTS In the entire cohort,the 6-,12-,and 24-mo survival rates were 88.9%,54.3%,and 14.1% in group A,and 45.8%,0%,and 0% in group B,respectively(P < 0.001). The median TTP and OS were significantly longer in group A than group B(TTP: 9.0 mo vs 3.4 mo,P < 0.001; OS: 12.3 mo vs 5.2 mo,P < 0.001). In the propensity score-matched cohort,the median OS was longer in group A than in group B(10.3 mo vs 6.0 mo,P < 0.001). Similarly,the median TTP was longer in group A than in group B(9.0 mo vs 3.4 mo,P < 0.001). Multivariate Cox analysis revealed that the EVBT combined with stent placement,TACE,and sorafenib strategy was an independent predictor of favorable OS(HR = 0.18,P < 0.001). CONCLUSION EVBT combined with stent placement,TACE,and sorafenib might be a safe and effective palliative treatment option for MPVTT.展开更多
In order to facilitate the extraction of the default mode network（DMN）, reduce the data complexity of the functional magnetic resonance imaging （fMRI）and overcome the restriction of the linearity of the mixing pro...In order to facilitate the extraction of the default mode network（DMN）, reduce the data complexity of the functional magnetic resonance imaging （fMRI）and overcome the restriction of the linearity of the mixing process encountered with the independent component analysis（ICA）, a framework of dimensionality reduction and nonlinear transformation is proposed. First, the principal component analysis（PCA）is applied to reduce the time dimension 153 594×128 of the fMRI data to 153 594×5 for simplifying complexity computation and obtaining 95% of the information. Secondly, a new kernel-based nonlinear ICA method referred as the kernel ICA（KICA）based on the Gaussian kernel is introduced to analyze the resting-state fMRI data and extract the DMN. Experimental results show that the KICA provides a better performance for the resting-state fMRI data analysis compared with the classical ICA. Furthermore, the DMN is accurately extracted and the noise is reduced.展开更多
The purpose of this paper is looking for associations between environmental factors and morphological parameters in tambaqui （Piaractus brachypomus） individuals to differentiate this species in lentic environments ...The purpose of this paper is looking for associations between environmental factors and morphological parameters in tambaqui （Piaractus brachypomus） individuals to differentiate this species in lentic environments （lake） and lotic （river）. In this, regard studied 30 specimens, 15 from lentic environment （lake） and 15 from lotic （river）. Also, on right profile of these 25 morphometric variables were measured. On data matrix a PCA （principal components analysis） based on morphometric correlations matrix, which was defined in the new morphologic space of these specimens （3 principal components） which explain 73.23% of variability. Fish projection in first two principal components showed a morphological differentiation between two environments （lentic and lotic）, with variables as, horizontal eye diameter, length maxilla, suggesting greater response of these fish in lotic environment by their adaptation to light conditions, predators threat and food distribution. Finally, in lotic environment these fish have thinner caudal peduncle, indicating greater plasticity, namely stylized fish.展开更多
For the electrostatically suspended gyro （ESG） with solid rotor, because the equatorial photoelectric sensor won＇t sense the equatorial marking line and output the correct damping control information when the nutat...For the electrostatically suspended gyro （ESG） with solid rotor, because the equatorial photoelectric sensor won＇t sense the equatorial marking line and output the correct damping control information when the nutation angle is small, the active damping with equatorial marking line will bring considerable error. The passive damping method by applying strong DC magnetic field requires too much time. So an active damping method by longitude marking lines is proposed to fulfill the fine damping for solid ESG rotor. The shape of rotor marking lines and the principle of fine damping are introduced. The simulation results prove that this fine damping method can effectively solve the problem of damping error introduced by active damping with equatorial marking line. The estimating resuits for damping time indicate that the fine damping time is less than 10 percent of passive damping time.展开更多
Since product metric on AdS space has played a very important role in Lorentz version of AdS/CFT correspondence, the Yang Mills equation on AdS space with this metric is considered and a static solution is obtained in...Since product metric on AdS space has played a very important role in Lorentz version of AdS/CFT correspondence, the Yang Mills equation on AdS space with this metric is considered and a static solution is obtained in this paper, which helps to understand the AdS/CFT correspondence of Yang Mills fields.展开更多
After experiencing racism in Canada, where multiculturalism emphasized ethnic differences and fixed identities rather than allowing for cultural interaction and hybridity, the author, B. Mukherjee, moves to the USA wh...After experiencing racism in Canada, where multiculturalism emphasized ethnic differences and fixed identities rather than allowing for cultural interaction and hybridity, the author, B. Mukherjee, moves to the USA whose biculturalism favors cultural interactions and fluid identities. Here she experiences the transformative powers of cultural interactions and frees herself and her work from the static power of cultural disjunction. Her personal experience highlights the need of immigrant characters to connect to the mainstream and not to be isolated from it The paper explores the problem of cultural adaptability and integration as experienced by Dimple, the main character in Mukherjee＇s novel Wife （1975）. Based upon contemporary research on cultural and social identity formation, the paper analyses Dimple＇s inner struggle of identity in the context of her immigrant status, and it relates her ultimately tragic response to loneliness and alienation resulting in cultural disjunction, non-adaptability, and non-assimilation.展开更多
By virtue of a 3∶1 complementary coordination strategy,a chiral heteroleptic metal-organic cage that con-tains divergent functional units,Pd‑R(Zn),was precisely constructed via self-assembly of monodentate variationa...By virtue of a 3∶1 complementary coordination strategy,a chiral heteroleptic metal-organic cage that con-tains divergent functional units,Pd‑R(Zn),was precisely constructed via self-assembly of monodentate variational Zn-salen ligands RZn and NADH(reduced nicotinamide adenine dinucleotide)mimic modified tridentate ligands with square-planar Pd ions.UV-Vis and luminescence spectra experiments reveal that different anions could selec-tively interact with different sites of Zn-salen modified metal-organic cages to achieve the structural regulation of cage compound,by using the differentiated host-guest electrostatic interactions of counter ions with metal-organic hosts.Compared to other anions,the presence of chloride ions caused the most significant fluorescence emission enhancement of Pd‑R(Zn),meanwhile,the UV-Vis absorption band attributed to the salen aromatic backbone showed an absorption decrease,and the metal-to-ligand induced peak displayed a blue shift effect.Circular dichro-ism and ^(1)H NMR spectra further demonstrate that the introduction of chloride anions is beneficial to keeping a more rigid scaffold.展开更多
The binding energy and Stark effect energy shifts of a shallow donor impurity state in a strained GaN/AlxGa1-xN spherical finite-potential quantum dot (QD) are calculated using a variational method based on the effect...The binding energy and Stark effect energy shifts of a shallow donor impurity state in a strained GaN/AlxGa1-xN spherical finite-potential quantum dot (QD) are calculated using a variational method based on the effective mass approximation. The binding energy is computed as a function of dot size and hydrostatic pressure. The numerical results show that the binding energy of the impurity state increases, attains a maximum value, and then decreases as the QD radius increases for any electric field. Moreover, the binding energy increases with the pressure for any size of dot. The Stark shift of the impurity energy for large dot size is much larger than that for the small dot size, and it is enhanced by the increase of electric field. We compare the binding energy of impurity state with and without strain effects, and the results show that the strain effects enhance the impurity binding energy considerably, especially for the small QD size. We also take the dielectric mismatch into account in our work.展开更多
文摘With the aid of commercial finite element analysis software package ANSYS,investigations are made on the contributions of main components to stiffness of the main module for parallel machine tools,and it is found that the frame is the main contributor.Then,influences of constraints,strut length and working ways of the main module have also been investigated.It can be concluded that when one of the main planes of the frame without linear drive unit is constrained,the largest whole stiffness can be acquired.And,the stiffness is much better when the main module is used in a vertical machine tool instead of a horizontal one.Finally,the principle of stiffness variation is summarized when the mobile platform reaches various positions within its working space and when various loads are applied.These achievements have provided critical instructions for the design of the main module for parallel machine tools.
基金Supported by the Project of Advanced and Appropriate Technique Generalization of Shanghai Health and Family Planning Committee,No.2013SY060the Scientific Program of Shanghai Municipal Heath Bureau,No.20124188
文摘AIM To evaluate the safety and efficacy of combined endovascular brachytherapy(EVBT),transarterial chemoembolization(TACE),and sorafenib to treat hepatocellular carcinoma(HCC) patients with main portal vein tumor thrombus(MPVTT).METHODS This single-center retrospective study involved 68 patients with unresectable HCC or those who were unfit for liver transplantation and percutaneous frequency ablation according to the BCLC classification. All patients had Child-Pugh classification grade A or B,Eastern Cooperative Oncology Group(ECOG)performance status of 0-2,and MPVTT. The patients received either EVBT with stent placement,TACE,and sorafenib(group A,n = 37),or TACE with sorafenib(group B,n = 31). The time to progression(TTP) and overall survival(OS) were evaluated by propensity score analysis.RESULTS In the entire cohort,the 6-,12-,and 24-mo survival rates were 88.9%,54.3%,and 14.1% in group A,and 45.8%,0%,and 0% in group B,respectively(P < 0.001). The median TTP and OS were significantly longer in group A than group B(TTP: 9.0 mo vs 3.4 mo,P < 0.001; OS: 12.3 mo vs 5.2 mo,P < 0.001). In the propensity score-matched cohort,the median OS was longer in group A than in group B(10.3 mo vs 6.0 mo,P < 0.001). Similarly,the median TTP was longer in group A than in group B(9.0 mo vs 3.4 mo,P < 0.001). Multivariate Cox analysis revealed that the EVBT combined with stent placement,TACE,and sorafenib strategy was an independent predictor of favorable OS(HR = 0.18,P < 0.001). CONCLUSION EVBT combined with stent placement,TACE,and sorafenib might be a safe and effective palliative treatment option for MPVTT.
基金Key Academic Discipline during the11th Five-Year Plan Period of Jiangsu Province
文摘In order to facilitate the extraction of the default mode network（DMN）, reduce the data complexity of the functional magnetic resonance imaging （fMRI）and overcome the restriction of the linearity of the mixing process encountered with the independent component analysis（ICA）, a framework of dimensionality reduction and nonlinear transformation is proposed. First, the principal component analysis（PCA）is applied to reduce the time dimension 153 594×128 of the fMRI data to 153 594×5 for simplifying complexity computation and obtaining 95% of the information. Secondly, a new kernel-based nonlinear ICA method referred as the kernel ICA（KICA）based on the Gaussian kernel is introduced to analyze the resting-state fMRI data and extract the DMN. Experimental results show that the KICA provides a better performance for the resting-state fMRI data analysis compared with the classical ICA. Furthermore, the DMN is accurately extracted and the noise is reduced.
文摘The purpose of this paper is looking for associations between environmental factors and morphological parameters in tambaqui （Piaractus brachypomus） individuals to differentiate this species in lentic environments （lake） and lotic （river）. In this, regard studied 30 specimens, 15 from lentic environment （lake） and 15 from lotic （river）. Also, on right profile of these 25 morphometric variables were measured. On data matrix a PCA （principal components analysis） based on morphometric correlations matrix, which was defined in the new morphologic space of these specimens （3 principal components） which explain 73.23% of variability. Fish projection in first two principal components showed a morphological differentiation between two environments （lentic and lotic）, with variables as, horizontal eye diameter, length maxilla, suggesting greater response of these fish in lotic environment by their adaptation to light conditions, predators threat and food distribution. Finally, in lotic environment these fish have thinner caudal peduncle, indicating greater plasticity, namely stylized fish.
文摘For the electrostatically suspended gyro （ESG） with solid rotor, because the equatorial photoelectric sensor won＇t sense the equatorial marking line and output the correct damping control information when the nutation angle is small, the active damping with equatorial marking line will bring considerable error. The passive damping method by applying strong DC magnetic field requires too much time. So an active damping method by longitude marking lines is proposed to fulfill the fine damping for solid ESG rotor. The shape of rotor marking lines and the principle of fine damping are introduced. The simulation results prove that this fine damping method can effectively solve the problem of damping error introduced by active damping with equatorial marking line. The estimating resuits for damping time indicate that the fine damping time is less than 10 percent of passive damping time.
基金Supported by National Key Basic Research Program of China under Grant No. 2004CB31800；National Natural Science Foundation of China under Grant No. 10375087；CUMT Foundation for Youth under Grant No. 2008A034, Qihang Project and Innovation Project of CUMT
文摘Since product metric on AdS space has played a very important role in Lorentz version of AdS/CFT correspondence, the Yang Mills equation on AdS space with this metric is considered and a static solution is obtained in this paper, which helps to understand the AdS/CFT correspondence of Yang Mills fields.
文摘After experiencing racism in Canada, where multiculturalism emphasized ethnic differences and fixed identities rather than allowing for cultural interaction and hybridity, the author, B. Mukherjee, moves to the USA whose biculturalism favors cultural interactions and fluid identities. Here she experiences the transformative powers of cultural interactions and frees herself and her work from the static power of cultural disjunction. Her personal experience highlights the need of immigrant characters to connect to the mainstream and not to be isolated from it The paper explores the problem of cultural adaptability and integration as experienced by Dimple, the main character in Mukherjee＇s novel Wife （1975）. Based upon contemporary research on cultural and social identity formation, the paper analyses Dimple＇s inner struggle of identity in the context of her immigrant status, and it relates her ultimately tragic response to loneliness and alienation resulting in cultural disjunction, non-adaptability, and non-assimilation.
文摘By virtue of a 3∶1 complementary coordination strategy,a chiral heteroleptic metal-organic cage that con-tains divergent functional units,Pd‑R(Zn),was precisely constructed via self-assembly of monodentate variational Zn-salen ligands RZn and NADH(reduced nicotinamide adenine dinucleotide)mimic modified tridentate ligands with square-planar Pd ions.UV-Vis and luminescence spectra experiments reveal that different anions could selec-tively interact with different sites of Zn-salen modified metal-organic cages to achieve the structural regulation of cage compound,by using the differentiated host-guest electrostatic interactions of counter ions with metal-organic hosts.Compared to other anions,the presence of chloride ions caused the most significant fluorescence emission enhancement of Pd‑R(Zn),meanwhile,the UV-Vis absorption band attributed to the salen aromatic backbone showed an absorption decrease,and the metal-to-ligand induced peak displayed a blue shift effect.Circular dichro-ism and ^(1)H NMR spectra further demonstrate that the introduction of chloride anions is beneficial to keeping a more rigid scaffold.
基金supported by the National Natural Science Foundation of China (No.10964006)the Research Funds for the Science and Technology Innovation Team of Inner Mongolia Agricultural University (No. NDPYTD2010-7)
文摘The binding energy and Stark effect energy shifts of a shallow donor impurity state in a strained GaN/AlxGa1-xN spherical finite-potential quantum dot (QD) are calculated using a variational method based on the effective mass approximation. The binding energy is computed as a function of dot size and hydrostatic pressure. The numerical results show that the binding energy of the impurity state increases, attains a maximum value, and then decreases as the QD radius increases for any electric field. Moreover, the binding energy increases with the pressure for any size of dot. The Stark shift of the impurity energy for large dot size is much larger than that for the small dot size, and it is enhanced by the increase of electric field. We compare the binding energy of impurity state with and without strain effects, and the results show that the strain effects enhance the impurity binding energy considerably, especially for the small QD size. We also take the dielectric mismatch into account in our work.
