基于“五轮学说”探讨脏腑辨证在RP的应用

原发性视网膜色素变性(RP)是以进行性夜盲、视野渐窄伴视力持续性下降为主要表现的眼病,因其不可逆的特性,被认为是常见的致盲眼病之一。中医学认为,本病病机以肝肾亏损为本,病理性质多以虚为主,瘀为标。“五轮学说”为中医眼科特有的重要理论之一,为后世中医眼科辨证施治提供核心理论依据。本文旨在基于“五轮学说”,运用脏腑辨证理论,深入探讨其在治疗RP中的临床应用,分辨病性,加深认识,并以此为诊疗此病提供新的临床思路和方法。

基于“五轮八廓”学说治疗视网膜静脉阻塞之思路初探

视网膜静脉阻塞(RVO)是眼科临床常见的视网膜血管性疾病,由视网膜静脉血流阻塞所致,其继发的黄斑水肿(ME)已成为导致RVO患者视力受损的重要原因。保护患者黄斑区视功能对提高患者的治疗效果及生存质量具有重要意义。目前临床一线治疗方法抗血管内皮生长因子(VEGF)药物玻璃体腔注射虽短期疗效显著,但ME易复发,需多次反复用药,增加了患者的经济负担及手术风险,且治标而未治本。本文结合中医眼科传统"五轮八廓"学说,在传统中医理论基础上传承发展,从整体的角度看待视网膜血管病,创新提出"黄斑八廓"假说。借助现代眼科检测设备,从分析RVO继发黄斑周围区域视功能损伤的中医发病机理等方面,浅析基于脏腑辨证、生物全息律,个体化治疗RVO的思路。

Ophthalmic Syndrome Differentiation System and Digital Chinese Medicine

In traditional Chinese medicine(TCM),ophthalmic syndrome differentiation is an ophthalmology-specific method for identifying syndromes based on the“Five Orbiculi”theory.It was devised by Professor Qing-Hua PENG through an unprecedented combination of syndrome element differentiation and ophthalmic clinical practices,based on the Clinical Terminology of Chinese Medical Diagnosis and Treatment-Syndromes of the National Standards of the People's Republic of China.This approach integrates an ophthalmic syndrome differentiation system with digital Chinese medicine(DCM),and proposes the extraction of syndrome elements of ophthalmic diseases from research on DCM.These elements are then quantified and organized to form a model of digital diagnosis and treatment specific to ophthalmology,which should help to achieve synergistic development of the ophthalmic syndrome differentiation system and DCM.