Peripherally inserted central catheter(PICC)is extensively used in critical care settings,because it plays a vital role in providing safe central venous entry.However,PICC is associated with several complications,whic...Peripherally inserted central catheter(PICC)is extensively used in critical care settings,because it plays a vital role in providing safe central venous entry.However,PICC is associated with several complications,which should be detected to shorten the duration of patients'improvement,reduce health care cost,and lessen the incidence of various PICC-related complications.Therefore,this study aimed to outline current literature on PICC procedures,potential complications,and measures for prevention.Understanding evidence-based guidelines regarding insertion technique,early detection of complications,and care bundle of PICC is significant in complication prevention.Implementation of education,training,and appropriate multidisciplinary approaches on PICC care among nurses and caregivers is the key to preventing complications.Thus,the strict care of indwelling PICC lines,the targeted and reasonable PICCassociated complication prevention,and nursing care have a major clinical significance in reducing the occurrence of potential PICC complications.展开更多
To date many monitoring techniques have been used to determine the efficacy of surgical correction of mitral valve disease. The most common non-invasive method in use is echocardiography which can assess the myocardia...To date many monitoring techniques have been used to determine the efficacy of surgical correction of mitral valve disease. The most common non-invasive method in use is echocardiography which can assess the myocardial and mitral valve function changes after mitral valve replacement procedures. In this study, we investigated the five-year follow-up echocardiographic results of 143 patients undergoing mitral valve replacement with preservation of subvalvular apparatus to analyze the recovery of myocardial and mitral valve functions.展开更多
Background QT dispersion (QTd) is a predictor of ventricular arrhythmia. Ventricular arrhythmia is an important factor influencing morbidity and mortality in patients with aortic stenosis. Surgical aortic valve repl...Background QT dispersion (QTd) is a predictor of ventricular arrhythmia. Ventricular arrhythmia is an important factor influencing morbidity and mortality in patients with aortic stenosis. Surgical aortic valve replacement reduced the QTd in this patients group. However, the effect of transcatheter aortic valve implantation (TAVI) on QTd in patients with aortic stenosis is unknown. The aim of this study was to investigate the effect of TAVI on QTd in patients with aortic stenosis. Methods Patients with severe aortic stenosis, who were not candi-dates for surgical aortic valve replacement due to contraindications or high surgical risk, were included in the study. All patients underwent electrocardiographic and echocardiographic evaluation before, and at the 6th month after TAVI, computed QTd and left ventricular mass index (LVMI). Results A total 30 patients were admitted to the study (mean age 83.2 ± 1.0 years, female 21 and male 9, mean valve area 0.7 ± 3 mm2). Edwards SAPIEN heart valves, 23 mm (21 patients) and 26 mm (9 patients), by the transfemoral approach were used in the TAVI procedures. All TAVI procedures were successful. Both QTd and LVMI at the 6th month after TAVI were significantly reduced com-pared with baseline values of QTd and LVMI before TAVI (73.8 ± 4 ms vs. 68 ± 2 ms, P=0.001 and 198 ± 51 g/m2 vs. 184 ± 40 g/m2, P=0.04, respectively). There was a significant correlation between QTd and LVMI (r=0.646, P〈0.001). Conclusions QTd, which malign ventricular arrhythmia marker, and LVMI were significantly reduced after TAVI procedure. TAVI may decrease the possibility of ventricu-lar arrhythmia in patients with aortic stenosis.展开更多
The subcutaneous implantable cardioverter defibrillators (SICD) is an altemative to the transvenous ICD for the prevention of sudden cardiac death (SCD). Multiple studies have shown that the SICD is safe and effec...The subcutaneous implantable cardioverter defibrillators (SICD) is an altemative to the transvenous ICD for the prevention of sudden cardiac death (SCD). Multiple studies have shown that the SICD is safe and effective in treating ventricular arrhythmias. While earlier stud- ies mainly enrolled younger patients with channelopathies, more recent reports included patients with "typical" indications for ICD therapy for the prevention of SCD. In this review we summarize the data available to date on the SICD while highlighting its pros and cons.展开更多
Objective:This study aimed to explore health care team members’understanding of the factors influencing the optimal selection of central venous access devices(CVADs).Methods:The data of the study was collected using ...Objective:This study aimed to explore health care team members’understanding of the factors influencing the optimal selection of central venous access devices(CVADs).Methods:The data of the study was collected using semi-structured interviews.Twenty-six hospital medical staff(four hospital manager,15 head nurses,7 nurse)with experience in peripheral or central catheterization from four regions(Northern China,Southern China,Northwest China,and Qinghai-Tibet China)in China were interviewed between June and October 2021.Content analysis was used to analyze the data.Results:The results revealed five themes and 14 sub-themes.Patients:concerns,resources,requirements,and evaluation(security concerns,support resources,life requirements,evaluation among patients);nurses:awareness,knowledge,and popularizing methods(awareness of intravenous therapy,understanding of professional knowledge,forms of popularizing methods);doctors:support and involvement(support for decision-making,involvement in intravenous work);hospital managers:authority,quality control and continuing education(management of catheterization authority,quality control of intravenous infusion,investment in continuing education)and environment:differences and commonalities(differences in social support,and current commonalities).Conclusion:Nurses and other healthcare team members’understanding,selection,use,and recommendation of CVADs have an indirect effect on patients’decision-making.Therefore,hospital managers and government departments can indirectly strengthen medical team cooperation and improve learning education in order to improve the safety of patients receiving intravenous infusions.展开更多
Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens, and the influence of each regimen on hospital stays after device implantation...Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens, and the influence of each regimen on hospital stays after device implantation. Methods We prospectively enrolled 364 patients receiving the cardiac rhythm device implantations in Fuwai Hospital from July 2012 to December 2013. Bleeding complications including pocket hematoma, hemothorax, cardiac tamponade and blood transfusion requirement were measured as endpoints. Post operation hospital stay was also included in the endpoints. Results Bleeding complications were detected in 15 patients (14 with hematoma, one with hemothorax) out of all 364 patients (4.12%). Dual antiplatelet therapy (DAT) significantly increased hematoma (19.3%) compared with aspi- fin treatment (ASA) (3.2%, P = 0.001) and no antiplatelet therapy (1.9%, P 〈 0.001). There was no significant difference in incidence of pocket hematoma between the ASA group and the control group (P = 0.45). The post procedure hospital stay was longer in DAT group (5.45 ± 2.01 days) compared to those in the ASA group (3.65 ± 1.37 days, P 〈 0.05) or control group (3.99 ± 2.27 days, P 〈 0.05). Pocket hema- toma was considered an independent predictor of hospital stay prolongation (OR: 5.26; 95% CI: 1.56-16.64; P = 0.007). Conclusions Among the Chinese patients undergoing device implantation in this study, the use of dual antiplatelet agents significantly increased the risk of pocket hematoma complications and led to a longer hospital stay. Use of aspirin alone did not increase the risk.展开更多
An experimental investigation of irregular wave forces on quasi-ellipse caisson structures is presented. Irregular waves were generated based on the Jonswap spectrum with two significant wave heights, and the spectrum...An experimental investigation of irregular wave forces on quasi-ellipse caisson structures is presented. Irregular waves were generated based on the Jonswap spectrum with two significant wave heights, and the spectrum peak periods range from 1.19 s to 1.81 s. Incident wave directions relative to the centre line of the multiple caissons are from 0° to 22.5°. The spacing between caissons ranges from 2 to 3 times that of the width of the caisson. The effects of these parameters on the wave forces of both the perforated and non-perforated caissons were compared and analyzed. It was found that the perforated caisson can reduce wave forces, especially in the transverse direction. Furthermore, the relative interval and incident wave direction have significant effects on the wave forces in the case of multiple caissons.展开更多
Current guidelines for implantable cardioverter-defibrillator (ICD) therapy in heart failure patients were established by multiple device Irials; however, very few geriatric patients (patients ≥ 65 years old) wer...Current guidelines for implantable cardioverter-defibrillator (ICD) therapy in heart failure patients were established by multiple device Irials; however, very few geriatric patients (patients ≥ 65 years old) were included in these studies. This article explores the controversies of ICD implantation in the geriatric population, management of delivered ICD therapy in this age group, and the end of life care in patients with ICD.展开更多
Seepage is one of the main causes for the deformation and instability of canal slopes in Xinjiang,China.In this study,centrifugal model tests under wetting-drying(WD)and wetting-drying-freezing-thawing(WDFT)cycles wer...Seepage is one of the main causes for the deformation and instability of canal slopes in Xinjiang,China.In this study,centrifugal model tests under wetting-drying(WD)and wetting-drying-freezing-thawing(WDFT)cycles were performed to investigate the water infiltration characteristics below a canal.The results show that the shallow soil of the canal models was fully saturated in the wetting process.Compared with the canal model under the WD cycles,the canal model under the WDFT cycles had larger saturated areas and a higher degree of saturation below the canal top after each cycle,indicating that the freezing-thawing(FT)process in the WDFT cycles promoted the water infiltration behavior below the canal slope.The cracks on the surface of the canal model under the cyclic action of WDFT developed further and had a higher connectivity,which provided the conditions for slope instability from a transverse tensile crack running through the canal top.On this basis,a field test was conducted to understand the water infiltration distribution below a typical canal in Xinjiang,China,which also verified the accuracy of the centrifugal results.This study provides a preliminary basis for the maintenance and seepage treatment of canals in Xinjiang,China.展开更多
Background Cardiac implantable electronic devices (CIEDs) greatly improve survival and life quality of patients. However, there are gender differences regarding both the utilization and benefit of these devices. In ...Background Cardiac implantable electronic devices (CIEDs) greatly improve survival and life quality of patients. However, there are gender differences regarding both the utilization and benefit of these devices. In this prospective CIED registry, we aim to appraise the gender differences in CIED utilization in China. Methods Twenty centers from 14 provinces in China were included in our registry study. All patients who underwent a CIED implantation in these twenty centers between Jan 2015 and Dec 2016 were included. Results A total of 8570 patients were enrolled in the baseline cohort, including 7203 pacemaker, 664 implantable cardiac defibrillators (ICD) implants and 703 cardiac resynchronization therapy device (CRT/D). Totally, 4117 (48.0%) CIED patients were female, and more than 59% pacemaker patients were female, but women account only one third of ICD or CRT/D implantation in this registry. There were significant differences between genders at pacemaker and ICD indications. Female was more likely received a pacemaker due to sick sinus syndrome (SSS) (63.9% vs. 51.0%, P 〈 0.001). Female patients receiving an ICD were more likely due to cardiac ion channel disease (29.2% vs. 4.2%, P 〈 0.001). The percentage of utilization of dual-chamber pacemaker in female patients was significantly higher than male (85.3% vs. 81.1%, P 〈 0.001). But male patients were more likely received a cardiac resynchronization therapy devices with defibrillator than female (56.5% vs. 41.9%, P = 0.001). In pacemaker patient, male was more likely to have structure heart disease (31.3% vs. 28.0%, P = 0.002). In ICD patient, male patients were more likely to have ischemic heart disease (48.2% vs. 29.2%, P 〈 0.001). The mean age of women at the time of CRT/D implantation was older than men (P = 0.014). Nonischemic cardiomyopathy (70.9%) was the most common etiology in the patients who underwent the treat?ment of CRT/D, no matter male or female. Conclusions In real-world setting, female do have different epidemiology, pathophysiology and clinical presentation of many cardiac rhythm disorders when compared with male, and all these factors may affect the utilization of CIED implantation. But it also possibility that cultural and socioeconomic features may play a role in this apparent discrimination.展开更多
Virtualization is a common technology for resource sharing in data center. To make efficient use of data center resources, the key challenge is to map customer demands (modeled as virtual data center, VDC) to the ph...Virtualization is a common technology for resource sharing in data center. To make efficient use of data center resources, the key challenge is to map customer demands (modeled as virtual data center, VDC) to the physical data center effectively. In this paper, we focus on this problem. Distinct with previous works, our study of VDC embedding problem is under the assumption that switch resource is the bottleneck of data center networks (DCNs). To this end, we not only propose relative cost to evaluate embedding strategy, decouple embedding problem into VM placement with marginal resource assignment and virtual link mapping with decided source-destination based on the property of fat-tree, but also design the traffic aware embedding algorithm (TAE) and first fit virtual link mapping (FFLM) to map virtual data center requests to a physical data center. Simulation results show that TAE+FFLM could increase acceptance rate and reduce network cost (about 49% in the case) at the same time. The traffie aware embedding algorithm reduces the load of core-link traffic and brings the optimization opportunity for data center network energy conservation.展开更多
Background Evaluation of patient outcomes following transcatheter aortic valve implantation (TAVI) has usually been based on survival and clinical improvement. Studies on quality of life are limited, and data from c...Background Evaluation of patient outcomes following transcatheter aortic valve implantation (TAVI) has usually been based on survival and clinical improvement. Studies on quality of life are limited, and data from comprehensive assessments after the procedure are lacking. Methods Sixty patients referred for cardiac rehabilitation after TAVI underwent in-hospital and after-discharge multidimensional assessments to evaluate clinical, functional, and nutritional statuses, degree of autonomy, cognitive impairment, depression and quality of life. Results On admission to rehabilitation, approximately half of the patients had severe functional impairment and dependence for basic activities of daily living. During their hospital stay, one-third of the patients suffered significant clinical complications and two had to be transferred to the implantation center. Despite this, the overall outcome was very good. All of the remaining patients were clinically stable at discharge and functional status, autonomy and quality of life were improved in most. During a mean follow-up of 540 days (range: 192-738 days), five patients died from noncardiac causes, three were hospitalized for cardiac events, and nine for non cardiac reasons. Functional status and autonomy remained satisfactory in the majority of patients and most continued to live independently. Conclusions Patients referred for rehabilitation after TAVI are often very frail, with a high grade of functional impairment, dependence on others and high risk of clinical complications. During a rehabilitation programme, based on a multidimensional assessment and intervention, most patients showed significant improvement in functional status, quality of life, and autonomy, which remained stable in the majority of subjects during mid-term follow-up.展开更多
Pedestrians intercepted near the exits of a subway station in downtown Hong Kong were surveyed using a questionnaire and quota sampling in October 2012. The survey sampled 408 residents and tourists aged 16 and above....Pedestrians intercepted near the exits of a subway station in downtown Hong Kong were surveyed using a questionnaire and quota sampling in October 2012. The survey sampled 408 residents and tourists aged 16 and above. The awareness of the 16 ads. ranged from 18 to 80 percent with an average 43.5 percent. The layouts of the two subway ads. received highest awareness were focused and had a clear distinction between foreground and background. Average ad awareness was comparable to that reported in two similar studies of subway ads. conducted in the 1990s. Average ad awareness of subway ads. was higher than that of outdoor advertising measured using similar methodology in 2010s. Respondents demonstrated positive attitudes toward subway advertising, and reported that subway ads. that drew their attention were those with creative ideas, vivid colors, and large-than-life size execution.展开更多
Objectives:This study aims to investigate the environmental and individual factors contributing to male nurses'psychological well-being and to explore the psychological mechanisms that may explain the links betwee...Objectives:This study aims to investigate the environmental and individual factors contributing to male nurses'psychological well-being and to explore the psychological mechanisms that may explain the links between nurses'practice environment and work engagement,thereby presenting the implications for nurse managers.Methods:A total of 161 male nurses from three tertiary first-class hospitals in Changsha City in China participated in the study.We collected the data using the Practice Environment Scale of the Nursing Work Index,the Psychological Capital Questionnaire,and the Utrecht Work Engagement Scale.Results:Scores of male nurses'practice environment(2.88±0.31),psychological capital(4.42±0.62),and work engagement(3.17±1.39)were all above the midpoint;however,the subscales"the nursing staffing and resources adequacy"(2.72±0.48),"hope"(4.33±0.72),and"dedication"(2.96±1.61)scored lowest.Nurses'practice environment and psychological capital positively predicted nurses'work engagement;psychological capital fully mediated the influence of nurses'practice environment on work engagement.Conclusions:Creating a supportive nursing practice environment can increase male nurses'work engagement by developing their psychological capital.Nurse managers can then provide reasonable workload and pathways for male nurses to achieve goals,thereby fostering their hope.展开更多
文摘Peripherally inserted central catheter(PICC)is extensively used in critical care settings,because it plays a vital role in providing safe central venous entry.However,PICC is associated with several complications,which should be detected to shorten the duration of patients'improvement,reduce health care cost,and lessen the incidence of various PICC-related complications.Therefore,this study aimed to outline current literature on PICC procedures,potential complications,and measures for prevention.Understanding evidence-based guidelines regarding insertion technique,early detection of complications,and care bundle of PICC is significant in complication prevention.Implementation of education,training,and appropriate multidisciplinary approaches on PICC care among nurses and caregivers is the key to preventing complications.Thus,the strict care of indwelling PICC lines,the targeted and reasonable PICCassociated complication prevention,and nursing care have a major clinical significance in reducing the occurrence of potential PICC complications.
文摘To date many monitoring techniques have been used to determine the efficacy of surgical correction of mitral valve disease. The most common non-invasive method in use is echocardiography which can assess the myocardial and mitral valve function changes after mitral valve replacement procedures. In this study, we investigated the five-year follow-up echocardiographic results of 143 patients undergoing mitral valve replacement with preservation of subvalvular apparatus to analyze the recovery of myocardial and mitral valve functions.
文摘Background QT dispersion (QTd) is a predictor of ventricular arrhythmia. Ventricular arrhythmia is an important factor influencing morbidity and mortality in patients with aortic stenosis. Surgical aortic valve replacement reduced the QTd in this patients group. However, the effect of transcatheter aortic valve implantation (TAVI) on QTd in patients with aortic stenosis is unknown. The aim of this study was to investigate the effect of TAVI on QTd in patients with aortic stenosis. Methods Patients with severe aortic stenosis, who were not candi-dates for surgical aortic valve replacement due to contraindications or high surgical risk, were included in the study. All patients underwent electrocardiographic and echocardiographic evaluation before, and at the 6th month after TAVI, computed QTd and left ventricular mass index (LVMI). Results A total 30 patients were admitted to the study (mean age 83.2 ± 1.0 years, female 21 and male 9, mean valve area 0.7 ± 3 mm2). Edwards SAPIEN heart valves, 23 mm (21 patients) and 26 mm (9 patients), by the transfemoral approach were used in the TAVI procedures. All TAVI procedures were successful. Both QTd and LVMI at the 6th month after TAVI were significantly reduced com-pared with baseline values of QTd and LVMI before TAVI (73.8 ± 4 ms vs. 68 ± 2 ms, P=0.001 and 198 ± 51 g/m2 vs. 184 ± 40 g/m2, P=0.04, respectively). There was a significant correlation between QTd and LVMI (r=0.646, P〈0.001). Conclusions QTd, which malign ventricular arrhythmia marker, and LVMI were significantly reduced after TAVI procedure. TAVI may decrease the possibility of ventricu-lar arrhythmia in patients with aortic stenosis.
文摘The subcutaneous implantable cardioverter defibrillators (SICD) is an altemative to the transvenous ICD for the prevention of sudden cardiac death (SCD). Multiple studies have shown that the SICD is safe and effective in treating ventricular arrhythmias. While earlier stud- ies mainly enrolled younger patients with channelopathies, more recent reports included patients with "typical" indications for ICD therapy for the prevention of SCD. In this review we summarize the data available to date on the SICD while highlighting its pros and cons.
基金Practice Teaching research project of Shandong University (No.2021Y240).
文摘Objective:This study aimed to explore health care team members’understanding of the factors influencing the optimal selection of central venous access devices(CVADs).Methods:The data of the study was collected using semi-structured interviews.Twenty-six hospital medical staff(four hospital manager,15 head nurses,7 nurse)with experience in peripheral or central catheterization from four regions(Northern China,Southern China,Northwest China,and Qinghai-Tibet China)in China were interviewed between June and October 2021.Content analysis was used to analyze the data.Results:The results revealed five themes and 14 sub-themes.Patients:concerns,resources,requirements,and evaluation(security concerns,support resources,life requirements,evaluation among patients);nurses:awareness,knowledge,and popularizing methods(awareness of intravenous therapy,understanding of professional knowledge,forms of popularizing methods);doctors:support and involvement(support for decision-making,involvement in intravenous work);hospital managers:authority,quality control and continuing education(management of catheterization authority,quality control of intravenous infusion,investment in continuing education)and environment:differences and commonalities(differences in social support,and current commonalities).Conclusion:Nurses and other healthcare team members’understanding,selection,use,and recommendation of CVADs have an indirect effect on patients’decision-making.Therefore,hospital managers and government departments can indirectly strengthen medical team cooperation and improve learning education in order to improve the safety of patients receiving intravenous infusions.
文摘Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens, and the influence of each regimen on hospital stays after device implantation. Methods We prospectively enrolled 364 patients receiving the cardiac rhythm device implantations in Fuwai Hospital from July 2012 to December 2013. Bleeding complications including pocket hematoma, hemothorax, cardiac tamponade and blood transfusion requirement were measured as endpoints. Post operation hospital stay was also included in the endpoints. Results Bleeding complications were detected in 15 patients (14 with hematoma, one with hemothorax) out of all 364 patients (4.12%). Dual antiplatelet therapy (DAT) significantly increased hematoma (19.3%) compared with aspi- fin treatment (ASA) (3.2%, P = 0.001) and no antiplatelet therapy (1.9%, P 〈 0.001). There was no significant difference in incidence of pocket hematoma between the ASA group and the control group (P = 0.45). The post procedure hospital stay was longer in DAT group (5.45 ± 2.01 days) compared to those in the ASA group (3.65 ± 1.37 days, P 〈 0.05) or control group (3.99 ± 2.27 days, P 〈 0.05). Pocket hema- toma was considered an independent predictor of hospital stay prolongation (OR: 5.26; 95% CI: 1.56-16.64; P = 0.007). Conclusions Among the Chinese patients undergoing device implantation in this study, the use of dual antiplatelet agents significantly increased the risk of pocket hematoma complications and led to a longer hospital stay. Use of aspirin alone did not increase the risk.
基金Foundation item: Supported by the National Natural Science Foundation of China under Grant No. 51109032, and the National Natural Science Foundation of China under Grant No. 50921001.
文摘An experimental investigation of irregular wave forces on quasi-ellipse caisson structures is presented. Irregular waves were generated based on the Jonswap spectrum with two significant wave heights, and the spectrum peak periods range from 1.19 s to 1.81 s. Incident wave directions relative to the centre line of the multiple caissons are from 0° to 22.5°. The spacing between caissons ranges from 2 to 3 times that of the width of the caisson. The effects of these parameters on the wave forces of both the perforated and non-perforated caissons were compared and analyzed. It was found that the perforated caisson can reduce wave forces, especially in the transverse direction. Furthermore, the relative interval and incident wave direction have significant effects on the wave forces in the case of multiple caissons.
文摘Current guidelines for implantable cardioverter-defibrillator (ICD) therapy in heart failure patients were established by multiple device Irials; however, very few geriatric patients (patients ≥ 65 years old) were included in these studies. This article explores the controversies of ICD implantation in the geriatric population, management of delivered ICD therapy in this age group, and the end of life care in patients with ICD.
基金Project(2017YFC0405100)supported by the National Key Research and Development Program of ChinaProjects(51879166,51709185,51909170)supported by the National Natural Science Foundation of China+1 种基金Project(SKLFSE201909)supported by the Open Research Fund Program of State Key Laboratory of Permafrost Engineering,ChinaProject(2018M640500)supported by Postdoctoral Science Foundation of China。
文摘Seepage is one of the main causes for the deformation and instability of canal slopes in Xinjiang,China.In this study,centrifugal model tests under wetting-drying(WD)and wetting-drying-freezing-thawing(WDFT)cycles were performed to investigate the water infiltration characteristics below a canal.The results show that the shallow soil of the canal models was fully saturated in the wetting process.Compared with the canal model under the WD cycles,the canal model under the WDFT cycles had larger saturated areas and a higher degree of saturation below the canal top after each cycle,indicating that the freezing-thawing(FT)process in the WDFT cycles promoted the water infiltration behavior below the canal slope.The cracks on the surface of the canal model under the cyclic action of WDFT developed further and had a higher connectivity,which provided the conditions for slope instability from a transverse tensile crack running through the canal top.On this basis,a field test was conducted to understand the water infiltration distribution below a typical canal in Xinjiang,China,which also verified the accuracy of the centrifugal results.This study provides a preliminary basis for the maintenance and seepage treatment of canals in Xinjiang,China.
文摘Background Cardiac implantable electronic devices (CIEDs) greatly improve survival and life quality of patients. However, there are gender differences regarding both the utilization and benefit of these devices. In this prospective CIED registry, we aim to appraise the gender differences in CIED utilization in China. Methods Twenty centers from 14 provinces in China were included in our registry study. All patients who underwent a CIED implantation in these twenty centers between Jan 2015 and Dec 2016 were included. Results A total of 8570 patients were enrolled in the baseline cohort, including 7203 pacemaker, 664 implantable cardiac defibrillators (ICD) implants and 703 cardiac resynchronization therapy device (CRT/D). Totally, 4117 (48.0%) CIED patients were female, and more than 59% pacemaker patients were female, but women account only one third of ICD or CRT/D implantation in this registry. There were significant differences between genders at pacemaker and ICD indications. Female was more likely received a pacemaker due to sick sinus syndrome (SSS) (63.9% vs. 51.0%, P 〈 0.001). Female patients receiving an ICD were more likely due to cardiac ion channel disease (29.2% vs. 4.2%, P 〈 0.001). The percentage of utilization of dual-chamber pacemaker in female patients was significantly higher than male (85.3% vs. 81.1%, P 〈 0.001). But male patients were more likely received a cardiac resynchronization therapy devices with defibrillator than female (56.5% vs. 41.9%, P = 0.001). In pacemaker patient, male was more likely to have structure heart disease (31.3% vs. 28.0%, P = 0.002). In ICD patient, male patients were more likely to have ischemic heart disease (48.2% vs. 29.2%, P 〈 0.001). The mean age of women at the time of CRT/D implantation was older than men (P = 0.014). Nonischemic cardiomyopathy (70.9%) was the most common etiology in the patients who underwent the treat?ment of CRT/D, no matter male or female. Conclusions In real-world setting, female do have different epidemiology, pathophysiology and clinical presentation of many cardiac rhythm disorders when compared with male, and all these factors may affect the utilization of CIED implantation. But it also possibility that cultural and socioeconomic features may play a role in this apparent discrimination.
基金This research was partially supported by the National Grand Fundamental Research 973 Program of China under Grant (No. 2013CB329103), Natural Science Foundation of China grant (No. 61271171), the Fundamental Research Funds for the Central Universities (ZYGX2013J002, ZYGX2012J004, ZYGX2010J002, ZYGX2010J009), Guangdong Science and Technology Project (2012B090500003, 2012B091000163, 2012556031).
文摘Virtualization is a common technology for resource sharing in data center. To make efficient use of data center resources, the key challenge is to map customer demands (modeled as virtual data center, VDC) to the physical data center effectively. In this paper, we focus on this problem. Distinct with previous works, our study of VDC embedding problem is under the assumption that switch resource is the bottleneck of data center networks (DCNs). To this end, we not only propose relative cost to evaluate embedding strategy, decouple embedding problem into VM placement with marginal resource assignment and virtual link mapping with decided source-destination based on the property of fat-tree, but also design the traffic aware embedding algorithm (TAE) and first fit virtual link mapping (FFLM) to map virtual data center requests to a physical data center. Simulation results show that TAE+FFLM could increase acceptance rate and reduce network cost (about 49% in the case) at the same time. The traffie aware embedding algorithm reduces the load of core-link traffic and brings the optimization opportunity for data center network energy conservation.
文摘Background Evaluation of patient outcomes following transcatheter aortic valve implantation (TAVI) has usually been based on survival and clinical improvement. Studies on quality of life are limited, and data from comprehensive assessments after the procedure are lacking. Methods Sixty patients referred for cardiac rehabilitation after TAVI underwent in-hospital and after-discharge multidimensional assessments to evaluate clinical, functional, and nutritional statuses, degree of autonomy, cognitive impairment, depression and quality of life. Results On admission to rehabilitation, approximately half of the patients had severe functional impairment and dependence for basic activities of daily living. During their hospital stay, one-third of the patients suffered significant clinical complications and two had to be transferred to the implantation center. Despite this, the overall outcome was very good. All of the remaining patients were clinically stable at discharge and functional status, autonomy and quality of life were improved in most. During a mean follow-up of 540 days (range: 192-738 days), five patients died from noncardiac causes, three were hospitalized for cardiac events, and nine for non cardiac reasons. Functional status and autonomy remained satisfactory in the majority of patients and most continued to live independently. Conclusions Patients referred for rehabilitation after TAVI are often very frail, with a high grade of functional impairment, dependence on others and high risk of clinical complications. During a rehabilitation programme, based on a multidimensional assessment and intervention, most patients showed significant improvement in functional status, quality of life, and autonomy, which remained stable in the majority of subjects during mid-term follow-up.
文摘Pedestrians intercepted near the exits of a subway station in downtown Hong Kong were surveyed using a questionnaire and quota sampling in October 2012. The survey sampled 408 residents and tourists aged 16 and above. The awareness of the 16 ads. ranged from 18 to 80 percent with an average 43.5 percent. The layouts of the two subway ads. received highest awareness were focused and had a clear distinction between foreground and background. Average ad awareness was comparable to that reported in two similar studies of subway ads. conducted in the 1990s. Average ad awareness of subway ads. was higher than that of outdoor advertising measured using similar methodology in 2010s. Respondents demonstrated positive attitudes toward subway advertising, and reported that subway ads. that drew their attention were those with creative ideas, vivid colors, and large-than-life size execution.
文摘Objectives:This study aims to investigate the environmental and individual factors contributing to male nurses'psychological well-being and to explore the psychological mechanisms that may explain the links between nurses'practice environment and work engagement,thereby presenting the implications for nurse managers.Methods:A total of 161 male nurses from three tertiary first-class hospitals in Changsha City in China participated in the study.We collected the data using the Practice Environment Scale of the Nursing Work Index,the Psychological Capital Questionnaire,and the Utrecht Work Engagement Scale.Results:Scores of male nurses'practice environment(2.88±0.31),psychological capital(4.42±0.62),and work engagement(3.17±1.39)were all above the midpoint;however,the subscales"the nursing staffing and resources adequacy"(2.72±0.48),"hope"(4.33±0.72),and"dedication"(2.96±1.61)scored lowest.Nurses'practice environment and psychological capital positively predicted nurses'work engagement;psychological capital fully mediated the influence of nurses'practice environment on work engagement.Conclusions:Creating a supportive nursing practice environment can increase male nurses'work engagement by developing their psychological capital.Nurse managers can then provide reasonable workload and pathways for male nurses to achieve goals,thereby fostering their hope.