文化实验厂3.0的“共感”制造 深圳金威啤酒厂旧址重生

都市实践建筑事务所在金威啤酒厂项目更新中提出了“即地制造”理念。作者认为,以文化运营持续引领工业遗存改造的文化实验厂3.0模式由此诞生。该项目无论在重生模式还是改造方式上,均呈现出对工业遗存场景的多维度“共感”制造意图。文章从重生模式、多维场景和空间体验三方面对其“即地制造”策略进行解析,研究该项目如何在工业生产逻辑向文化生产逻辑转型过程中,形成“共感”制造途径。文章认为,通过“密度”制造和场域呈现,可以激发现象学中对历史的、现代的多重信息叠加的共感体验,促使人们形成对工业遗存场所记忆及其再生产模式的理解。

论元宇宙中的“共感”与真实

元宇宙虚拟空间是包围物理现实与虚拟媒介的共延空间,元宇宙超越并融合现实世界,营造“共感—真实”效果。元宇宙通过媒介为介入数字叙事的人们提供“共感”体验,在这场体验中,元宇宙为“真实”提供了一个虚拟场域,受众事实性的真实情绪感知与身体体验又削弱了虚拟场域的边界感。最终,元宇宙传递的符号意义被接收者整合,受众携带当下的感知,主动“弥合”或“悬搁”现实和虚幻之间的距离,自主地“沉浸”于元宇宙空间;又在与人的共处中,真实地保留了经验世界中感官的丰富性。

欣赏《始得西山宴游记》中的共感

审美欣赏中的“共感”又称“感会”、“会心”、“应会”等等,指的是主体与对象之间心物两契,产生情感上的共振共鸣,即是西方美学所说的审美移情。

Asymmetrical Fabry-Perot cavity slot micro-ring resonator and its sensing characteristics

To achieve high quality factor and high-sensitivity refractive index sensor,a slot micro-ring resonator(MRR)based on asymmetric Fabry-Perot(FP)cavity was proposed.The structure consisted of a pair of elliptical holes to form an FP cavity and a microring resonator.The two different optical modes generated by the micro-ring resonator were destructively interfered to form a Fano line shape,which improved the system sensitivity while obtaining a higher quality factor and extinction ratio.The transmission principle of the structure was analyzed by the transfer matrix method.The transmission spectrum and mode field distribution of the proposed structure were simulated by the finite difference time domain(FDTD)method,and the key structural parameters affecting the Fano line shape in the device were optimized.The simulation results show that the quality factor of the device reached 22037.1,and the extinction ratio was 23.9 dB.By analyzing the refractive index sensing characteristics,the sensitivity of the structure was 354 nm·RIU−1,and the detection limit of the sensitivity was 2×10−4 RIU.Thus,the proposed compact asymmetric FP cavity slot micro-ring resonator has obvious advantages in sensing applications owing to its excellent performance.

情感智商与课堂教学气氛的营造

从情感智商的角度出发,论述了教师与学生的情感在课堂教学气氛中的作用,并阐述了教师如何运用“共感”能力来营造良好的课堂教学气氛。

Characteristics of suspended planar-type gas sensor based on MEMS process

In order to simplify the fabrication process,distribute the temperature uniformly and reduce the power consumption of the micro-hotplate（MHP） gas sensor,a planar-type gas sensor based on SnO2 thin film with suspended structure is designed through a MEMS process.Steady-state thermal analysis of the gas sensor and the closed membrane type sensor where the membrane overlaps the Si substrate is carried out with the finite element model,and it is shown that the suspended planar-type gas sensor has a more homogeneous temperature distribution and a lower power consumption.When the maximum temperature on the sensor reaches 383℃,the power consumption is only 7 mW,and the temperature gradient across the thin film is less than 14℃.To overcome the fragility of the suspended beams,a novel fabrication process in which the deposition of the gas sensing film occurs prior to the formation of suspended beams is proposed.The back side of the Si substrate is etched through deep reactive ion etching（DRIE） to avoid chemical pollution of the front side.The fabrication steps in which only four masks are used for the photolithography are described in detail.The Fe doped SnO2 thin film synthesized by sol-gel spin-coating is used as the gas sensing element.The device is tested on hydrogen and exhibits satisfactory sensing performance.The sensitivity increases with the rise of the concentration from 50×10-6 to 2000×10-6,and reaches about 30 at 2000×10-6.

Fabrication of an AlAs/In_(0.53)Ga_ ( 0.47)As/InAs Resonant Tunneling Diode on InP Substrate for High-Speed Circuit Applications

A high performance AlAs/In0.53 Ga0.47 As/InAs resonant tunneling diode （RTD） on InP substrate is fabricated by inductively coupled plasma etching. This RTD has a peak-to-valley current ratio （PVCR） of 7. 57 and a peak current density Jp = 39.08kA/cm^2 under forward bias at room temperature. Under reverse bias, the corresponding values are 7.93 and 34.56kA/cm^2 . A resistive cutoff frequency of 18.75GHz is obtained with the effect of a parasitic probe pad and wire. The slightly asymmetrical current-voltage characteristics with a nominally symmetrical structure are also discussed.

RIGHT INFERIOR FRONTAL GYRUS PROCESSING OF VISUAL EROTIC INFORMATION BASED ON fMRI

Visually-induced erotic arousal evoked by pornographic visual stimuli, such as films or photographs, is a common occurrence in human behavior. The brain activation associated with visual erotic stimuli in heterosexual right handed females is studied. Functional magnetic resonance imaging is used to investigate 15 female partici- panterotic arousal induced by visual stimuli in film and picture forms, respectively, performing three or more times during their menstrual cycle on a 3.0T magnetic resonance imaging scanner. There is activation of a set of bilateral brain areas, including the inferior lateral occipital cortex, the anterior supramarginal gyrus, the parietal operculum cortex, the superior parietal lobules, the right inferior frontal gyrus, the cerebellum, the hypothalamus, the thalamus, the hippocampus, and the mid-brain. From different regions, the brain activation is observed and the inferior frontal gyrus has found to be task-independent. Furthermore, the right inferior frontal gyrus has more activation than the left inferior frontal gyrus. The result shows that the right inferior frontal gyrus plays an important role in pornographic information processing rather than being activated stimuli property specific. It is presented for the first time that the functional laterization of the inferior frontal gyrus is bi-directional rather than single （left） directional.

Coinfection of TT virus and response to interferon therapy in patients with chronic hepatitis B or C

AIM: To investigate the serum positive percentage of TT virus (TTV) in patients with chronic hepatitis B or C and the response of the coinfected TTV to interferon (IFN) during IFN therapy for chronic hepatitis B and C. METHODS: We retrospectively studied the serum samples of 70 patients with chronic hepatitis who had received IFN-alpha therapy from January 1997 to June 2000, which included 40 cases of hepatitis B and 30 hepatitis C. All the patients had been followed up for at least 6 months after the end of IFN therapy. The serum TTV DNA was detected using the polymerase chain reaction (PCR) before and every month during the course of IFN treatment. RESULTS: TTV infection was detected in 15% (6/40) of the chronic hepatitis B group and 30% (9/30) of the chronic hepatitis C group. Loss of serum TTV DNA during IFN therapy occurred in 3 of 6 patients (50%) and 6 of 9 (67%) of hepatitis B and C groups, respectively. Seronegativity of TTV was found all during the first month of IFN therapy in the 9 patients. There was no correlation between the seroconversion of TTV and the biochemical changes of the patients. CONCLUSION: TTV is not infrequently coinfected in patients with chronic hepatitis B and C in Taiwan, and more than half of the TTV infections are IFN-sensitive. However, the loss of serum TTV DNA does not affect the clinical course of the patients with chronic hepatitis B or C.

Predominance of Plasmodium malariae-falciparum Co-Infection by Molecular Speciation in Bangolan, North West Region of Cameroon

Although microscopy still remains the gold standard for the diagnosis of malaria, rapid diagnostic tests （RDTs） and PCR assays have been shown to be sensitive and specific. Very few comparative studies have been reported of the three diagnostic methods on the same samples in vulnerable groups. Microscopy, RDTs and PCR assays were used for detection and speciation of Plasmodium falciparum （P）＇）, Plasmodium malariae （Pm） and Plasmodium ovale （Po） in patients in a rice culture savanna ecotype. Fifty four children and 16 pregnant women presenting with a fever were recruited. Bloods collected was used for thin and thick smears, perform RDTs and spotted blood on filter paper for DNA extraction and performance of a PCR. Mean parasitaemia was 37,619.06 （＋ 33,599.04） p/pL and 7,512.5 （＋ 12,446.11） p/μL for children and pregnant women, respectively. A total of 87.14% were positive by microscopy, 85.71% by RDTs and 90% by PCR. Distribution of Plasmodium species as identified by PCR was 72.86% Pf/Pm, 11.43% Pf/Pm/Po and 5.43% Pm while 10% were negative. Cohen＇s Kappa value for PCR and RDTs was K = 0.75 （CI = 0.28-1.22） while PCR and microscopy was K = 0.64 （CI = 0.18-1.10）. Malaria infection in Bangolan was mostly due to mix infection predominantly P. falciparum/P, malariae.

Effects of co-existing microalgae and grazers on the production of hemolytic toxins in Karenia mikimotoi

Karenia mikimotoi （Miyake ＆ Kominami ex Oda） Hansen ＆ Moestrup is associated with harmful algal blooms in temperate and subtropical zones of the world. The hemolytic substances produced by K. mikimotoi are thought to cause mortality in fishes and invertebrates. We evaluated the composition of the hemolytic toxin produced by K. mikimotoi cultured in the laboratory using thin-layer chromatography. In addition, we evaluated the effect of co-occuring algae （Prorocentrum donghaiense and Alexandrium tamarense） and the cladoceran grazer Moina mongoliea on hemolytic toxin production in K. mikimotoi. The hemolytic toxins from K. mikimotoi were a mixture of 2 liposaccharides and 1 lipid. Waterborne clues from P. donghaiense and A. tamarense inhibited the growth of K. mikimotoi but increased the production of hemolytic toxins. Conversely, K. mikimotoi strongly inhibited the growth of caged P. donghaiense and A. tamarense. In addition, the ingestion of K. mikimotoi by M. mongolica induced the production of hemolytic toxins in K. mikimotoi. Taken together, our results suggest that the presence of other microalgae and grazers may be as important as environmental factors for controlling the production of hemolytic substances. K. mikimotoi secreted allelochemicals other than unstable fatty acids with hemolytic activity. The production of hemolytic toxins in dinofiagellates was not only dependent on resource availability, but also on the risk of predation. Hemolytic toxins likely play an important role as chemical deterrents secreted by K. mikimotoi.

Crimean-Congo Hemorrhagic Fever: An Overview

Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic viral infection that is a serious threat to humans. The disease is widely distributed in Africa, Asia, and Europe and has developed into a serious public health concern. Humans become infected through the bites of ticks, by contact with a patient with CCHF, or by contact with blood or tissues from viremic livestock. Microvascular instability and impaired hemostasis are the hallmarks of the infection. Infection in human begins with nonspecific febrile symptoms, but may progress to a serious hemorrhagic syndrome with high mortality rates. Enzyme-linked immunoassay (ELISA) and polymerase chain reaction (PCR) are the most used and specific tests for the diagnosis. The mainstay of treatment is supportive. Although definitive studies are not available, ribavirin is suggested to be effective especially at the earlier phase of the infection. Uses of universal protective measures are the best way to avoid the infection. In this review, all aspects of CCHF are overviewed in light of the current literature.

Polydopamine-Assisted Fabrication of Fiber-Optic Localized Surface Plasmon Resonance Sensor Based on Gold Nanoparticles

A fast and facile method of fabricating fiber-optic localized surface plasmon resonance sensors baseff on spherical gold nanoparticles was introduced in this study. The gold nanoparticles with an average diameter of 55 nm were synthesized via the Turkevich method and were then immobilized onto the surface of an uncladded sensor probe using a polydopamine layer. To obtain a sensor probe with high sensitivity to changes in the refractive index, a set of key optimization parameters, including the sensing length, coating time of the potydopamine layer, and coating time of the gold nanoparticles, were investigated. The sensitivity of the optimized sensor probe was 522.80 nm per refractive index unit, and the probe showed distinctive wavelength shifts when the refractive index was changed from 1.328 6 to 1.398 7. When stored in deionized water at 4 ℃, the sensor probe proved to be stable over a period of two weeks. The sensor also exhibited advantages, such as low cost, fast fabrication, and simple optical setup, which indicated its potential application in remote sensing and real-time detection.

Aircraft attitude estimation of MEMS sensor based on modified particle filter

The non-linearity problem of aircraft system could not be overcome by using the MEMS sensor only.In order to improve the accuracy of aerial vehicle attitude,an aircraft attitude estimation of the MEMS sensor based on modified particle filter is proposed.The aircraft attitude is optimized by the conjugate gradient method,and the drift error of gyroscope is reduced.Moreover,the particle weight is updated by the observed value to obtain an optimized state estimate.Finally,the conjugate gradient method and the modified particle filter are weightily combined to determine the optimal weighting factor.The attitude estimation is carried out with STM32 and MEMS sensor as the core to design system.The experimental results show that the static and dynamic attitude estimation performances of the aircraft are improved.The performances are well,the attitude data is relatively stable,and the tracking characteristics are better.Moreover,it has better robustness and stability.

Optimization of a fiber grating film sensor based on dual peak resonance

Based on the dual peak resonance of long-period fiber grating（LPFG）, a novel film sensor is presented, in which films sensitive to the surrounding gases are coated on the cladding of the fiber grating region, and the intervals of the dual peak resonant wavelengths change with the film refractive index. According to the coupled-mode theory, a triple-clad numerical model is developed to analyze the relation between the sensitivity Sn and the thin film optical parameters （the film thickness h3 and the refractive index n3） and the fiber grating parameters （the grating period A and the core index modulation σ）. By using optimization method, the optimal film optical parameters and the grating structure parameters are obtained. Numerical simulation shows that the sensitivity of this scheme to refractive index of the films is predicted to be more than 10-7. The theoretic analysis provides straightforward foundation for the actual highly sensitive film sensors.

Simulation and Analysis on Multiple Steady States of an Industrial Acetic Acid Dehydration System

In this work, an industrial acetic acid dehydration system via heterogeneous azeotropic distillation is simulated by Aspen Plus software. Residue curves are used to analyze the distillating behavior, and appropriate operating region of the system is determined. Based on steady states simulation, a sensitivity analysis is carried out to detect the output multiple steady states in the system. Different solution branches are observered when the flow rates of the feed stream and the organic reflux stream are selected as manipulated variables. The performance of the column under different steady states is different. A method is oroposed to achieve the desired steady state.

Worldwide epidemiology of liver hydatidosis including the Mediterranean area

The worldwide incidence and prevalence of cystic echinococcosis have fallen dramatically over the past several decades.Nonetheless,infection with Echinococcus granulosus(E.granulosus)remains a major public health issue in several countries and regions,even in places where it was previously at low levels,as a result of a reduction of control programmes due to economic problems and lack of resources.Geographic distribution differs by country and region depending on the presence in that country of large numbers of nomadic or semi-nomadic sheep and goat flocks that represent the intermediate host of the parasite,and their close contact with the final host,the dog,which mostly provides the transmission of infection to humans.The greatest prevalence of cystic echinococcosis in human and animal hosts is found in countries of the temperate zones,including several parts of Eurasia(the Mediterranean regions,southern and central parts of Russia,central Asia,China),Australia,some parts of America(especially South America)and north and east Africa.Echinococcosis is currently considered an endemic zoonotic disease in the Mediterranean region.The most frequent strain associated with human cystic echinococcosis appears to be the common sheep strain(G1).This strain appears to be widely distributed in all continents.The purpose of this review is to examine the distribution of E.granulosus and the epidemiology of a re-emerging disease such as cystic echinococcosis.

Synthesis and Characterization of Novel Temperature and pH Responsive Hydroxylpropyl Cellulose-based Graft Copolymers

In this study, double-hydrophilic hydroxylpropyl cellulose （HPC） based copolymers with poly（N- isopropylacrylamide） （PNIPAM） and poly（acrylic acid） （PAA） as graft chains were synthesized and characterized. The release behavior of drug-loaded micelles was studied. The results show that the hydrophilicity of copolymers improves as the pH increases, whereas the hydrophobicity of copolymers enhances as the temperature increases, and all the phase behaviors are reversible. The diameter of micelles decreases and then increases with pH increase. It shows different micellizing behavior under acidic and basic conditions according to the temperature increase. In vitro release experiments, which used theophylline as a model drug, show that the micelles enhance pH sensitivity in the release process.

New Progress in the Application of Satellite Thermal Infrared Imagery to Earthquake Prediction

The concept of stochastic resonance (SR) has been introduced into the analysis of satellite thermal infrared images. Six kinds of anomalous phenomena related to crustal movement were recognized in satellite thermal infrared images. Six diagnostic indicators for the prediction of global earthquakes with magnitude ≥6.0 and their quantitative evaluation standards have been established. The microscopic behavior of global crustal movement is successfully controlled by using satellite thermal infrared imagery, and the occurrence time and magnitude of over 80% of global strong earthquakes occurred since the foundation of the observation station have been successfully predicted. It is believed that the combination of satellite thermal infrared information with macroscopic anomalous phenomena will play an important role in earthquake hazard reduction.

Different cytokine response of primary colonic epithelial cells to commensal bacteria

AIM: To determine if primary murine colonic epithelial cells (CEC) respond to commensal bacteria and discriminate between different types of bacteria. METHODS: A novel CEC: bacteria co-culture system was used to compare the ability of the colonic commensal bacteria, Bacteroides ovatus, E coli(SLF) and Lactobacillus rhamnosus (LGG) to modulate production of different cytokines (n = 15) by primary CEC. Antibody staining and flow cytometry were used to investigate Toll-like receptor (TLR) expression by CEC directly ex vivo and TLR responsiveness was determined by examining the ability of TLR ligands to influence CEC cytokine production. RESULTS: Primary CEC constitutively expressed functional TLR2 and TLR4. Cultured in complete medium alone, CEC secreted IL-6, MCP-1 and IP-10 the levels of which were significantly increased upon addition of the TLR ligands peptidoglycan (PGN) and lipopolysaccharide (LPS). Exposure to the commensal bacteria induced or up-regulated different patterns of cytokine production and secretion.E coli induced production of MIP-1α/β and p defensin3 whereas B. ovatus and L. rhamnosus exclusively induced MCP-1 and MIP-2α expression, respectively. TNFa, RANTES and MEC were induced or up-regulated in response to some but not all of the bacteria whereas ENA78 and IP-10 were up-regulated in response to all bacteria. Evidence of bacterial interference and suppression of cytokine production was obtained from mixed bacterial: CEC co-cultures. Probiotic LGG suppressed E coli- and B. ovatus-induced cytokine mRNA accumulation and protein secretion. CONCLUSION: These observations demonstrate the ability of primary CEC to respond to and discriminate between different strains of commensal bacteria and identify a mechanism by which probiotic bacteria (LGG) may exert anti-inflammatory effects in vivo.