In this paper,transient electromagnetic method was used to carry out the feasibility study on the detection and recognition of chamber blasting misfire.Firstly,an electromagnetic background field was established in th...In this paper,transient electromagnetic method was used to carry out the feasibility study on the detection and recognition of chamber blasting misfire.Firstly,an electromagnetic background field was established in the test;secondly,a benign conductor was preset in the chamber,and then the background field was eliminated after the electromagnetic field was measured;thirdly,the transient electromagnetic field was measured again after blasting;at last,the chamber blasting misfire was detected and recognized by comparing the change of eddy current field of the preset benign conductor before and after blasting.The test results showed that:When the buried depth of aluminum box target was no more than 30 m,transient electromagnetic method can clearly identify the position of the aluminum box;when the buried depth of aluminum box was more than30 m,the buried depth and position of the aluminum box was not sure due to the unknown level of secondary eddy current field generated by aluminum box.展开更多
A 65-year-old man with cT1bN0M0 stage I middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiothe...A 65-year-old man with cT1bN0M0 stage I middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiotherapy and chemotherapy in a clinical trial. Anastomotic leakage occurred, but it spontaneously improved. At six months after the operation, he was rehospitalized with a cough and dysphagia. An esophago-bronchiole fistula and stenosis of the gastric tube were observed. He first underwent stent placement in the gastric tube. Two weeks later, the syringeal epithelium was burned by argon plasma coagulation after stent removal. Endoscopic occlusion was then performed for the fistula with two guidewire-assisted silicone spigots. Two weeks later, he was discharged on an oral diet, and he has not developed recurrence of the fistula or cancer for three years. This is the first report of endoscopic occlusion with a guidewire-assisted silicone spigot through the esophagus.展开更多
Uni-modal rainfall pattern has long dry spell wherein sweetpotato is scarce, expensive but cheap at harvest. The crop is mostly consumed, processed or sold. Extending shelf-life of roots is crucial for Malawi and Nort...Uni-modal rainfall pattern has long dry spell wherein sweetpotato is scarce, expensive but cheap at harvest. The crop is mostly consumed, processed or sold. Extending shelf-life of roots is crucial for Malawi and Northern Ghana as the crop has high value. Trials were conducted in the countries at the community level. In the dry season, temperature is cool in Malawi while warm in Ghana, but thru harmattan, the night is cool with low relative humidity. In Malawi, orange-fleshed sweetpotato Zondeni var., white and yellow types were assessed in three types of storage, Afghan ventilated pit store, storage in dry sand of pit-steps, and of a granary In Ghana, local moistened heap and sandbox were compared. In Malawi, weight losses were calculated relative to the quantity stored at start, it was not cumulative. At 1.5 months no significant difference was among treatments. By 3.5 months the pit-steps method emerged to be superior and continued to 6.5 months. Losses in granary were due to shriveling, in the pit-stepsdue to termites and rats, and in ventilated pit due to termites, rats and Java black rot. Sprouting was high in pit-steps, but it was simply removed and roots returned to storage. At 6.5 months, the beta-carotene of Zondeni roots was traceable. Farmers gained high price when selling them as roots were scarce. Women favored the pit-steps because it was manageable. In Ghana, the sandbox was superior to local moistened heap. Methods designed were suitable for home consumption, but will require modification for commercialization.展开更多
This overview discusses old and new results as to the controversy on the past glacier extension in High Asia, which has been debated for 35 years now. This paper makes an attempt to come closer to a solution. H.v. Wis...This overview discusses old and new results as to the controversy on the past glacier extension in High Asia, which has been debated for 35 years now. This paper makes an attempt to come closer to a solution. H.v. Wissmann's interpretation (1959) of a small-scale glaciation contrasts with M. Kuhle's reconstruction (1974) of a large-scale glaciation with a 2.4 million km2 extended Qinghai-Xizang (Tibetan) inland glaciation and a Himalaya-Karakorum icestream network. Both opinions find support but also contradiction in the International and Chinese literature (Academia Sinica). The solution of this question is of supraregional importance because of the subtropical position of the concerned areas. In case of large albedo-intensive ice surfaces, a global cooling would be the energetical consequence and, furthermore, a breakdown of the summer monsoon. The current and interglacial heat-low above the very effective heating panel of the Qinghai-Xizang (Tibetan) Plateau exceeding 4000 m, which gives rise to this monsoon circulation, would be replaced by the cold-high of an inland ice. In addition, the plate-tectonically created Pleistocene history of the uplift of High Asia — should the occasion arise up to beyond the snowline (ELA) —would attain a paleoclimatically great, perhaps global importance. In case of a heavy superimposed ice load, the question would come up as to the glacio-isostatic interruption of this primary uplift. The production of the loesses sedimentated in NE-China and their very probable glacial genesis as well as an eustatic lowering of the sea-level by 5 to 7 m in the maximum case of glaciation are immediately tied up with the question of glaciation we want to discuss. Not the least, the problems of biotopes of the sanctuary-centres of flora and fauna, i.e., interglacial re-settlement, are also dependent on it. On the basis of this Quaternary- geomorphological-glaciological connection, future contributions are requested on the past glaciation, the current and glacial permafrost table and periglacial development, the history of uplift, and the development of Ice Age lakes and loess, but also on the development of vegetation and fauna in High Asia.展开更多
People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.
Glucose transporter 4 (GLUT4) is responsible for insulin-stimulated glucose transporting into the insulin-sensitive fat and muscle cells. The dynamics of GLUT4 storage vesicles (GSVs) remains to be explored and it is ...Glucose transporter 4 (GLUT4) is responsible for insulin-stimulated glucose transporting into the insulin-sensitive fat and muscle cells. The dynamics of GLUT4 storage vesicles (GSVs) remains to be explored and it is unclear how GSVs are arranged based on their mobility. We examined this issue in 3T3-L1 cells via investigating the three-dimensional mobility of single GSV labeled with EGFP-fused GLUT4. A thin layer of cytosol right adjacent to the plasma membrane was illuminated and successively imaged at 5 Hz under a total internal reflection fluorescence microscope with a penetration depth of 136 nm. Employing single particle tracking, the three-dimensional subpixel displacement of single GSV was tracked at a spatial precision of 22 nm. Both the mean square displacement and the diffusion coefficient were calculated for each vesicle. Tracking results revealed that vesicles moved as if restricted within a cage that has a mean radius of 160 nm, suggesting the presence of some intracellular tethering matrix. By constructing the histogram of the diffusion coefficients of GSVs, we observed a smooth distribution instead of the existence of distinct groups. The result indicates that GSVs are dynamically retained in a continuous and wide range of mobility rather than into separate classes.展开更多
Knowledge of the leaf anatomy of grassland plants is crucial for understanding how these plants adapt to the environment. Tibetan alpine grasslands and Inner Mongolian temperate grasslands are two major grassland type...Knowledge of the leaf anatomy of grassland plants is crucial for understanding how these plants adapt to the environment. Tibetan alpine grasslands and Inner Mongolian temperate grasslands are two major grassland types in northern China. Tibetan alpine grasslands occur in high-altitude regions where the low temperatures limit plant growth. Inner Mongolian temperate grasslands are found in arid regions where moisture is the limiting factor. Few comparative studies concerning the leaf anatomy of grassland plants of the Tibetan Plateau and Inner Mongolian Plateau have been conducted. We examined leaf characteristics at 71 sites and among 65 species, across the alpine grasslands of the Tibetan Plateau and the temperate grasslands of the Inner Mongolian Plateau. We compared the leaf structures of plants with different life forms and taxonomies, and their adaptation to arid or cold environments. We explored relationships among leaf features and the effects of climatic factors (i.e., growing season temperature and precipitation) on leaf characteristics. Our results showed that (i) there were significant differences in leaf anatomy between Tibetan alpine and Inner Mongolian temperate grasslands. Except for mesophyll cell density, the values obtained for thickness of leaf tissue, surface area and volume of mesophyll cells were larger on the Tibetan Plateau than on the Inner Mongolian Plateau. (ii) Within the same family or genus, leaf anatomy showed significant differences between two regions, and trends were consistent with those of whole species. (iii) Leaf anatomy of woody and herbaceous plants also showed significant differences between the regions. Except for mesophyll cell density, the values obtained for the thickness of leaf tissue, and the surface area and volume of mesophyll cells were larger in herbaceous than in woody plants. (iv) Leaf anatomical traits changed accordingly. Total leaf thickness, thicknesses of lower and upper epidermal cells, and surface area and volume of mesophyll cells were positively correlated, while mesophyll cell density was negatively associated with those traits. (v) Growing season temperature had stronger effects on leaf anatomy than growing season precipitation. Although the communities in Tibetan and Inner Mongolian grasslands were similar in appearance, leaf anatomy differed; this was probably due to the combined effects of evolutionary adaptation of plants to environment and environmental stress induced by climatic factors.展开更多
Objective: To observe the clinical efficacy of point needle embedding in treating constipation after thoracolumbar vertebral fracture. Methods: By random number table based on the admission sequence, 85 patients wit...Objective: To observe the clinical efficacy of point needle embedding in treating constipation after thoracolumbar vertebral fracture. Methods: By random number table based on the admission sequence, 85 patients with constipation after thoracolumbar vertebral fracture were randomized into an observation group of 43 cases and a control group of 42 cases. The observation group was intervened by point needle embedding with intradermal needles, while the control group was by point application with Chinese medication. The clinical efficacies were compared between the two groups after intervention. Results: After treatment, the initial defecation time and bowel movement condition were compared. Despite the residual feeling in the initial defecation, the initial defecation time and bowel movements of the observation group were significantly superior to those of the control group (P〈0.05, P〈0.01); the total effective rate was 90.7% in the observation group versus 73.8% in the control group, and the difference was statistically significant (P〈0.05). Conclusion: Point needle embedding can produce a better therapeutic efficacy than Chinese medicinal application in treating constipation after thoracolumbar vertebral fracture; besides, it's easy-to-operate.展开更多
Objective:To observe the clinical efficacy difference in treating irritable bowel syndrome-diarrhea(IBS-D)of liver-qi stagnation and spleen-deficiency pattern with different treatment protocols,and the effects on seru...Objective:To observe the clinical efficacy difference in treating irritable bowel syndrome-diarrhea(IBS-D)of liver-qi stagnation and spleen-deficiency pattern with different treatment protocols,and the effects on serum levels of 5-hydroxytryptamine(5-HT),substance P(SP)and vasoactive intestinal peptide(VIP),for unveiling the mechanism of intradermal needle therapy plus pinaverium bromide in treating IBS-D.Methods:A total of 123 IBS-D patients were divided into an observation group,a Western medication group and an integrated Western and Chinese medication group using the random number table method,with 41 cases in each group.The Western medication group was given oral pinaverium bromide,50 mg each time and 3 times a day.The integrated Western and Chinese medication group was given additional Chinese herbal medicine Tong Xie Yao Fang,one dose each day.The observation group was given additional intradermal needle therapy on the basis of the Western medication group.The whole intervention lasted for 6 weeks.Before and after treatment,the scores of gastrointestinal symptoms,traditional Chinese medicine(TCM)symptoms,irritable bowel syndrome(IBS)symptom severity scale(IBS-SSS)and IBS quality of life(IBS-QOL)questionnaire,as well as the serum levels of 5-HT,SP and VIP were observed.The clinical efficacy was estimated.Results:The total effective rate was 92.7%in the observation group,68.3%in the Western medication group and 78.1%in the integrated Western and Chinese medication group.The total effective rate was higher in the observation group than in the other two groups,and higher in the integrated Western and Chinese medication group than in the Western medication group,showing statistical significance(all P<0.05).After treatment,the scores of gastrointestinal symptoms,TCM symptoms and IBS-SSS showed significant decreases in the three groups,presenting statistical significance compared with the baseline(all P<0.05);the scores of gastrointestinal symptoms,TCM symptoms and IBS-SSS were notably lower in the observation group than in the other two groups(all P<0.05),and lower in the integrated Western and Chinese medication group than in the Western medication group(all P<0.05).After treatment,the eight component scores of IBS-QOL showed significant increases in the three groups compared with the baseline(all P<0.05);the eight component scores in IBS-QOL were significantly higher in the observation group than in the other two groups(all P<0.05),and higher in the integrated Western and Chinese medication group than in the Western medication group(all P<0.05).After treatment,the serum levels of 5-HT,SP and VIP decreased markedly in the three groups compared with the baseline(all P<0.05);the serum levels of 5-HT,SP and VIP were significantly lower in the observation group than in the other two groups(all P<0.05),and lower in the integrated Western and Chinese medication group than in the Western medication group(P<0.05).Conclusion:Treatment with intradermal needle therapy plus pinaverium bromide results in significant improvements in the gastrointestinal symptoms and quality of life in patients with IBS-D of liver-qi stagnation and spleen deficiency pattern,and effectively regulates the gastrointestinal hormone production.展开更多
Objective:To observe the clinical efficacy of intradermal needle therapy for urinary retention after cervical cancer surgery.Methods:A total of 100 patients with urinary retention after cervical cancer surgery were ra...Objective:To observe the clinical efficacy of intradermal needle therapy for urinary retention after cervical cancer surgery.Methods:A total of 100 patients with urinary retention after cervical cancer surgery were randomized into a control group and an observation group,with 50 cases in each group.The control group was treated with basic nursing only,and the observation group was treated with additional intradermal needle therapy.Both groups were treated for 2 courses of treatment.The main symptom scores and residual urine volume of the two groups were observed before and after treatment,and the inpatient time,catheter indwelling time and the clinical efficacy were compared between the two groups.Results:The total effective rate was 96.0%in the observation group and 88.0% in the control group,and the difference between the two groups was statistically significant(P<0.05).After treatment,the main symptom scores and residual urine volume in both groups decreased significantly(all P<0.0S),and the scores and residual urine volume in the observation group were significantly lower than those in the control group(all P<0.05).The inpatient time and catheter indwelling time in the observation group were significantly shorter than those in the control group(both P<0.05).Conclusion:Intradermal needle therapy has an obvious effect in improving symptoms of urinary retention after cervical cancer surgery,and the effect is significantly more persistent than that of simple basic nursing.展开更多
Inland lakes and alpine glaciers are important water resources on the Tibetan Plateau. Understanding their variation is crucial for accurate evaluation and prediction of changes in water supply and for retrieval and a...Inland lakes and alpine glaciers are important water resources on the Tibetan Plateau. Understanding their variation is crucial for accurate evaluation and prediction of changes in water supply and for retrieval and analysis of climatic information. Data from previous research on 35 alpine lakes on the Tibetan Plateau were used to investigate changes in lake water level and area. In terms of temporal changes, the area of the 35 alpine lakes could be divided into five groups: rising, falling-rising, rising-falling, fluctuating, and falling. In terms of spatial changes, the area of alpine lakes in the Himalayan Mountains, the Karakoram Mountains, and the Qaidam Basin tended to decrease; the area of lakes in the Naqu region and the Kunlun Mountains increased; and the area of lakes in the Hoh Xil region and Qilian Mountains fluctuated. Changes in lake water level and area were correlated with regional changes in climate. Reasons for changes in these lakes on the Tibetan Plateau were analyzed, including precipitation and evaporation from meteorological data, glacier meltwater from the Chinese glacier inventories. Several key problems, e.g. challenges of monitoring water balance, limitations to glacial area detection, uncertainties in detecting lake water-level variations and variable region boundaries of lake change types on the Tibetan Plateau were discussed. This research has most indicative significance to regional climate change.展开更多
Intradermal needle therapy is a kind of therapy by embedding specially-made short needles in the points for long time retaining.It is also known as needleembedding therapy,develops from the ancient method of needle re...Intradermal needle therapy is a kind of therapy by embedding specially-made short needles in the points for long time retaining.It is also known as needleembedding therapy,develops from the ancient method of needle retaining [1].展开更多
Store-operated Ca2+ entry(SOCE) controls intracellular Ca2+ homeostasis and regulates a wide range of cellular events including proliferation,migration and invasion.The discovery of STIM proteins as Ca2+ sensors and O...Store-operated Ca2+ entry(SOCE) controls intracellular Ca2+ homeostasis and regulates a wide range of cellular events including proliferation,migration and invasion.The discovery of STIM proteins as Ca2+ sensors and Orai proteins as Ca2+ channel pore forming units provided molecular tools to understand the physiological function of SOCE.Many studies have revealed the pathophysiological roles of Orai and STIM in tumor cells.This review focuses on recent advances in SOCE and its contribution to tumorigenesis.Altered Orai and/or STIM functions may serve as biomarkers for cancer prognosis,and targeting the SOCE pathway may provide a novel means for cancer treatment.展开更多
The North China and the neighbouring Mongolia in Asian Interior is characterized by extremely dry climate, resulted in one of the world's major dust emission centres. Deciphering the source region of Asian dust is cr...The North China and the neighbouring Mongolia in Asian Interior is characterized by extremely dry climate, resulted in one of the world's major dust emission centres. Deciphering the source region of Asian dust is critical for revealing the mechanism of the dust production, interpreting the paleo-environrnental records of eolian deposits, predicting the overall environmental effects of dust, and setting the strategies for the control of contemporary dust storms. This paper summarizes the geochemical methods applied to the source tracing of Asian dust. Nd-Sr isotopes were the most extensively studied source tracer of Asian dust and have been successfully applied in many cases. Geochemistry of detrital monomineral shows great theoretical advantages in source tracing and deserves further studies. The short-range transportation of Chinese loess with direction similar to that of the prevailing near surface wind is revealed. Source tracing also shows that the Asian dust has two ultimate material sources from the northern margin of the Tibetan Plateau and the Central Asian Orogen, which confirms the importance of mountain processes in the production of silt eolian particles. Based on the recent progresses on the source tracing of Asian dust, discussions are expanded on the natural background of Asian dust storms and potential anthropogenic influence, the materials evolution of the source regions of Asian dust and its relationships with climate changes and Tibetan uplift, and the role of Tibetan uplift in the Asian dust system.展开更多
文摘In this paper,transient electromagnetic method was used to carry out the feasibility study on the detection and recognition of chamber blasting misfire.Firstly,an electromagnetic background field was established in the test;secondly,a benign conductor was preset in the chamber,and then the background field was eliminated after the electromagnetic field was measured;thirdly,the transient electromagnetic field was measured again after blasting;at last,the chamber blasting misfire was detected and recognized by comparing the change of eddy current field of the preset benign conductor before and after blasting.The test results showed that:When the buried depth of aluminum box target was no more than 30 m,transient electromagnetic method can clearly identify the position of the aluminum box;when the buried depth of aluminum box was more than30 m,the buried depth and position of the aluminum box was not sure due to the unknown level of secondary eddy current field generated by aluminum box.
文摘A 65-year-old man with cT1bN0M0 stage I middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiotherapy and chemotherapy in a clinical trial. Anastomotic leakage occurred, but it spontaneously improved. At six months after the operation, he was rehospitalized with a cough and dysphagia. An esophago-bronchiole fistula and stenosis of the gastric tube were observed. He first underwent stent placement in the gastric tube. Two weeks later, the syringeal epithelium was burned by argon plasma coagulation after stent removal. Endoscopic occlusion was then performed for the fistula with two guidewire-assisted silicone spigots. Two weeks later, he was discharged on an oral diet, and he has not developed recurrence of the fistula or cancer for three years. This is the first report of endoscopic occlusion with a guidewire-assisted silicone spigot through the esophagus.
文摘Uni-modal rainfall pattern has long dry spell wherein sweetpotato is scarce, expensive but cheap at harvest. The crop is mostly consumed, processed or sold. Extending shelf-life of roots is crucial for Malawi and Northern Ghana as the crop has high value. Trials were conducted in the countries at the community level. In the dry season, temperature is cool in Malawi while warm in Ghana, but thru harmattan, the night is cool with low relative humidity. In Malawi, orange-fleshed sweetpotato Zondeni var., white and yellow types were assessed in three types of storage, Afghan ventilated pit store, storage in dry sand of pit-steps, and of a granary In Ghana, local moistened heap and sandbox were compared. In Malawi, weight losses were calculated relative to the quantity stored at start, it was not cumulative. At 1.5 months no significant difference was among treatments. By 3.5 months the pit-steps method emerged to be superior and continued to 6.5 months. Losses in granary were due to shriveling, in the pit-stepsdue to termites and rats, and in ventilated pit due to termites, rats and Java black rot. Sprouting was high in pit-steps, but it was simply removed and roots returned to storage. At 6.5 months, the beta-carotene of Zondeni roots was traceable. Farmers gained high price when selling them as roots were scarce. Women favored the pit-steps because it was manageable. In Ghana, the sandbox was superior to local moistened heap. Methods designed were suitable for home consumption, but will require modification for commercialization.
文摘This overview discusses old and new results as to the controversy on the past glacier extension in High Asia, which has been debated for 35 years now. This paper makes an attempt to come closer to a solution. H.v. Wissmann's interpretation (1959) of a small-scale glaciation contrasts with M. Kuhle's reconstruction (1974) of a large-scale glaciation with a 2.4 million km2 extended Qinghai-Xizang (Tibetan) inland glaciation and a Himalaya-Karakorum icestream network. Both opinions find support but also contradiction in the International and Chinese literature (Academia Sinica). The solution of this question is of supraregional importance because of the subtropical position of the concerned areas. In case of large albedo-intensive ice surfaces, a global cooling would be the energetical consequence and, furthermore, a breakdown of the summer monsoon. The current and interglacial heat-low above the very effective heating panel of the Qinghai-Xizang (Tibetan) Plateau exceeding 4000 m, which gives rise to this monsoon circulation, would be replaced by the cold-high of an inland ice. In addition, the plate-tectonically created Pleistocene history of the uplift of High Asia — should the occasion arise up to beyond the snowline (ELA) —would attain a paleoclimatically great, perhaps global importance. In case of a heavy superimposed ice load, the question would come up as to the glacio-isostatic interruption of this primary uplift. The production of the loesses sedimentated in NE-China and their very probable glacial genesis as well as an eustatic lowering of the sea-level by 5 to 7 m in the maximum case of glaciation are immediately tied up with the question of glaciation we want to discuss. Not the least, the problems of biotopes of the sanctuary-centres of flora and fauna, i.e., interglacial re-settlement, are also dependent on it. On the basis of this Quaternary- geomorphological-glaciological connection, future contributions are requested on the past glaciation, the current and glacial permafrost table and periglacial development, the history of uplift, and the development of Ice Age lakes and loess, but also on the development of vegetation and fauna in High Asia.
文摘People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.
文摘Glucose transporter 4 (GLUT4) is responsible for insulin-stimulated glucose transporting into the insulin-sensitive fat and muscle cells. The dynamics of GLUT4 storage vesicles (GSVs) remains to be explored and it is unclear how GSVs are arranged based on their mobility. We examined this issue in 3T3-L1 cells via investigating the three-dimensional mobility of single GSV labeled with EGFP-fused GLUT4. A thin layer of cytosol right adjacent to the plasma membrane was illuminated and successively imaged at 5 Hz under a total internal reflection fluorescence microscope with a penetration depth of 136 nm. Employing single particle tracking, the three-dimensional subpixel displacement of single GSV was tracked at a spatial precision of 22 nm. Both the mean square displacement and the diffusion coefficient were calculated for each vesicle. Tracking results revealed that vesicles moved as if restricted within a cage that has a mean radius of 160 nm, suggesting the presence of some intracellular tethering matrix. By constructing the histogram of the diffusion coefficients of GSVs, we observed a smooth distribution instead of the existence of distinct groups. The result indicates that GSVs are dynamically retained in a continuous and wide range of mobility rather than into separate classes.
基金supported by the Funds for Creative Research Groups of the National Natural Science Foundation of China (Grant No. 31021001)the Funds of the Chinese Academy of Sciences for Key Topics in Innovation Engineering (Grant No. KSCX2-YW-Z-0806)
文摘Knowledge of the leaf anatomy of grassland plants is crucial for understanding how these plants adapt to the environment. Tibetan alpine grasslands and Inner Mongolian temperate grasslands are two major grassland types in northern China. Tibetan alpine grasslands occur in high-altitude regions where the low temperatures limit plant growth. Inner Mongolian temperate grasslands are found in arid regions where moisture is the limiting factor. Few comparative studies concerning the leaf anatomy of grassland plants of the Tibetan Plateau and Inner Mongolian Plateau have been conducted. We examined leaf characteristics at 71 sites and among 65 species, across the alpine grasslands of the Tibetan Plateau and the temperate grasslands of the Inner Mongolian Plateau. We compared the leaf structures of plants with different life forms and taxonomies, and their adaptation to arid or cold environments. We explored relationships among leaf features and the effects of climatic factors (i.e., growing season temperature and precipitation) on leaf characteristics. Our results showed that (i) there were significant differences in leaf anatomy between Tibetan alpine and Inner Mongolian temperate grasslands. Except for mesophyll cell density, the values obtained for thickness of leaf tissue, surface area and volume of mesophyll cells were larger on the Tibetan Plateau than on the Inner Mongolian Plateau. (ii) Within the same family or genus, leaf anatomy showed significant differences between two regions, and trends were consistent with those of whole species. (iii) Leaf anatomy of woody and herbaceous plants also showed significant differences between the regions. Except for mesophyll cell density, the values obtained for the thickness of leaf tissue, and the surface area and volume of mesophyll cells were larger in herbaceous than in woody plants. (iv) Leaf anatomical traits changed accordingly. Total leaf thickness, thicknesses of lower and upper epidermal cells, and surface area and volume of mesophyll cells were positively correlated, while mesophyll cell density was negatively associated with those traits. (v) Growing season temperature had stronger effects on leaf anatomy than growing season precipitation. Although the communities in Tibetan and Inner Mongolian grasslands were similar in appearance, leaf anatomy differed; this was probably due to the combined effects of evolutionary adaptation of plants to environment and environmental stress induced by climatic factors.
文摘Objective: To observe the clinical efficacy of point needle embedding in treating constipation after thoracolumbar vertebral fracture. Methods: By random number table based on the admission sequence, 85 patients with constipation after thoracolumbar vertebral fracture were randomized into an observation group of 43 cases and a control group of 42 cases. The observation group was intervened by point needle embedding with intradermal needles, while the control group was by point application with Chinese medication. The clinical efficacies were compared between the two groups after intervention. Results: After treatment, the initial defecation time and bowel movement condition were compared. Despite the residual feeling in the initial defecation, the initial defecation time and bowel movements of the observation group were significantly superior to those of the control group (P〈0.05, P〈0.01); the total effective rate was 90.7% in the observation group versus 73.8% in the control group, and the difference was statistically significant (P〈0.05). Conclusion: Point needle embedding can produce a better therapeutic efficacy than Chinese medicinal application in treating constipation after thoracolumbar vertebral fracture; besides, it's easy-to-operate.
文摘Objective:To observe the clinical efficacy difference in treating irritable bowel syndrome-diarrhea(IBS-D)of liver-qi stagnation and spleen-deficiency pattern with different treatment protocols,and the effects on serum levels of 5-hydroxytryptamine(5-HT),substance P(SP)and vasoactive intestinal peptide(VIP),for unveiling the mechanism of intradermal needle therapy plus pinaverium bromide in treating IBS-D.Methods:A total of 123 IBS-D patients were divided into an observation group,a Western medication group and an integrated Western and Chinese medication group using the random number table method,with 41 cases in each group.The Western medication group was given oral pinaverium bromide,50 mg each time and 3 times a day.The integrated Western and Chinese medication group was given additional Chinese herbal medicine Tong Xie Yao Fang,one dose each day.The observation group was given additional intradermal needle therapy on the basis of the Western medication group.The whole intervention lasted for 6 weeks.Before and after treatment,the scores of gastrointestinal symptoms,traditional Chinese medicine(TCM)symptoms,irritable bowel syndrome(IBS)symptom severity scale(IBS-SSS)and IBS quality of life(IBS-QOL)questionnaire,as well as the serum levels of 5-HT,SP and VIP were observed.The clinical efficacy was estimated.Results:The total effective rate was 92.7%in the observation group,68.3%in the Western medication group and 78.1%in the integrated Western and Chinese medication group.The total effective rate was higher in the observation group than in the other two groups,and higher in the integrated Western and Chinese medication group than in the Western medication group,showing statistical significance(all P<0.05).After treatment,the scores of gastrointestinal symptoms,TCM symptoms and IBS-SSS showed significant decreases in the three groups,presenting statistical significance compared with the baseline(all P<0.05);the scores of gastrointestinal symptoms,TCM symptoms and IBS-SSS were notably lower in the observation group than in the other two groups(all P<0.05),and lower in the integrated Western and Chinese medication group than in the Western medication group(all P<0.05).After treatment,the eight component scores of IBS-QOL showed significant increases in the three groups compared with the baseline(all P<0.05);the eight component scores in IBS-QOL were significantly higher in the observation group than in the other two groups(all P<0.05),and higher in the integrated Western and Chinese medication group than in the Western medication group(all P<0.05).After treatment,the serum levels of 5-HT,SP and VIP decreased markedly in the three groups compared with the baseline(all P<0.05);the serum levels of 5-HT,SP and VIP were significantly lower in the observation group than in the other two groups(all P<0.05),and lower in the integrated Western and Chinese medication group than in the Western medication group(P<0.05).Conclusion:Treatment with intradermal needle therapy plus pinaverium bromide results in significant improvements in the gastrointestinal symptoms and quality of life in patients with IBS-D of liver-qi stagnation and spleen deficiency pattern,and effectively regulates the gastrointestinal hormone production.
文摘Objective:To observe the clinical efficacy of intradermal needle therapy for urinary retention after cervical cancer surgery.Methods:A total of 100 patients with urinary retention after cervical cancer surgery were randomized into a control group and an observation group,with 50 cases in each group.The control group was treated with basic nursing only,and the observation group was treated with additional intradermal needle therapy.Both groups were treated for 2 courses of treatment.The main symptom scores and residual urine volume of the two groups were observed before and after treatment,and the inpatient time,catheter indwelling time and the clinical efficacy were compared between the two groups.Results:The total effective rate was 96.0%in the observation group and 88.0% in the control group,and the difference between the two groups was statistically significant(P<0.05).After treatment,the main symptom scores and residual urine volume in both groups decreased significantly(all P<0.0S),and the scores and residual urine volume in the observation group were significantly lower than those in the control group(all P<0.05).The inpatient time and catheter indwelling time in the observation group were significantly shorter than those in the control group(both P<0.05).Conclusion:Intradermal needle therapy has an obvious effect in improving symptoms of urinary retention after cervical cancer surgery,and the effect is significantly more persistent than that of simple basic nursing.
基金The Major State Basic Research Development of China,No.2015CB954101National Mountain Flood Disaster Investigation Project,No.SHZH-IWHR-57+2 种基金The National Science and Technology Basic Special Project,No.2011FY11040-2National Natural Science Foundation of China,No.41171332The Surveying and Mapping Geoinformation Nonprofit Specific Project,No.201512033
文摘Inland lakes and alpine glaciers are important water resources on the Tibetan Plateau. Understanding their variation is crucial for accurate evaluation and prediction of changes in water supply and for retrieval and analysis of climatic information. Data from previous research on 35 alpine lakes on the Tibetan Plateau were used to investigate changes in lake water level and area. In terms of temporal changes, the area of the 35 alpine lakes could be divided into five groups: rising, falling-rising, rising-falling, fluctuating, and falling. In terms of spatial changes, the area of alpine lakes in the Himalayan Mountains, the Karakoram Mountains, and the Qaidam Basin tended to decrease; the area of lakes in the Naqu region and the Kunlun Mountains increased; and the area of lakes in the Hoh Xil region and Qilian Mountains fluctuated. Changes in lake water level and area were correlated with regional changes in climate. Reasons for changes in these lakes on the Tibetan Plateau were analyzed, including precipitation and evaporation from meteorological data, glacier meltwater from the Chinese glacier inventories. Several key problems, e.g. challenges of monitoring water balance, limitations to glacial area detection, uncertainties in detecting lake water-level variations and variable region boundaries of lake change types on the Tibetan Plateau were discussed. This research has most indicative significance to regional climate change.
文摘Intradermal needle therapy is a kind of therapy by embedding specially-made short needles in the points for long time retaining.It is also known as needleembedding therapy,develops from the ancient method of needle retaining [1].
文摘Store-operated Ca2+ entry(SOCE) controls intracellular Ca2+ homeostasis and regulates a wide range of cellular events including proliferation,migration and invasion.The discovery of STIM proteins as Ca2+ sensors and Orai proteins as Ca2+ channel pore forming units provided molecular tools to understand the physiological function of SOCE.Many studies have revealed the pathophysiological roles of Orai and STIM in tumor cells.This review focuses on recent advances in SOCE and its contribution to tumorigenesis.Altered Orai and/or STIM functions may serve as biomarkers for cancer prognosis,and targeting the SOCE pathway may provide a novel means for cancer treatment.
基金supported by National Natural Science Foundation of China (Grant No. 41021002)
文摘The North China and the neighbouring Mongolia in Asian Interior is characterized by extremely dry climate, resulted in one of the world's major dust emission centres. Deciphering the source region of Asian dust is critical for revealing the mechanism of the dust production, interpreting the paleo-environrnental records of eolian deposits, predicting the overall environmental effects of dust, and setting the strategies for the control of contemporary dust storms. This paper summarizes the geochemical methods applied to the source tracing of Asian dust. Nd-Sr isotopes were the most extensively studied source tracer of Asian dust and have been successfully applied in many cases. Geochemistry of detrital monomineral shows great theoretical advantages in source tracing and deserves further studies. The short-range transportation of Chinese loess with direction similar to that of the prevailing near surface wind is revealed. Source tracing also shows that the Asian dust has two ultimate material sources from the northern margin of the Tibetan Plateau and the Central Asian Orogen, which confirms the importance of mountain processes in the production of silt eolian particles. Based on the recent progresses on the source tracing of Asian dust, discussions are expanded on the natural background of Asian dust storms and potential anthropogenic influence, the materials evolution of the source regions of Asian dust and its relationships with climate changes and Tibetan uplift, and the role of Tibetan uplift in the Asian dust system.