AIM： To compare the one-day quadruple therapy with a standard 7-d triple therapy for H pylori eradication in a rural population of China. METHODS： A total of 396 patients with 13C-urea breath test positive for H pyl...AIM： To compare the one-day quadruple therapy with a standard 7-d triple therapy for H pylori eradication in a rural population of China. METHODS： A total of 396 patients with 13C-urea breath test positive for H pylori were assigned into two groups： 239 patients received one-day quadruple therapy （amoxicillin 2000 mg qid; metronidazole 500 mg qid; bismuth citrate 900 mg qid and lansoprazole 60 mg once daily） and 157 patients received 7-d standard triple therapy （amoxicillin 1000 mg bid; clarithromycin 500 mg bid and lansoprazole 30 mg bid）. All the patients underwent a 13C-UBT to assess the eradication of Hpylori infection six weeks after treatment. RESULTS： Two hundred and twenty-nine patients completed the one-day therapy （95.8%） and 148 patients completed the 7-d therapy （94.2%）. The oneday therapy eradicated H pylori infection in 64 patients （27.95%）. In contrast, 103 patients （69.59%） were Hpylori negative after the 7-d therapy （P 〈 0.01）. CONCLUSION： This pilot study suggests there is no beneficial effect of the one-day therapy in treatment ofHpylori infection compared with the 7-d standard therapy.展开更多
China is experiencing a fast process of farmland conversion which is conducted mainly by local governments to fuel economic development.Social tension is aroused and policy makers take great concerns on coordinating i...China is experiencing a fast process of farmland conversion which is conducted mainly by local governments to fuel economic development.Social tension is aroused and policy makers take great concerns on coordinating interests among different stakeholders,especially for increasing farmers′ interest.The purpose of this study is to get some insights related to land acquisition institution by exploring farmers′ perception to farmland conversion.Participatory Rural Appraisal(PRA) was applied for the investigation in peri-urban area,of Xining City,Qinghai Province,China.The total of 519 householders from 15 villages completed valid questionnaire survey from July to November,2012.The results indicate that farmland conversion has several impacts on farmers′ life.Most farmers are gradually adapting to city life.Higher living expenses and more income are perceived by farmers with average score of 4.21 and 2.69,respectively.The average scores of 2.38 and 2.46 are for improvement of life security and more job opportunities.Farmers expect to get some stable ways of compensation in addition to lump-sum compensation in cash.Stable subsidies every year and obtaining same number of land received strong proposal.And these two options are cited by 49.6% and 43.9% of respondents.Farmland conversion brings about cleaner living condition and more amenities,but lower air visibility and drier air.Results reflect landless farmers′ economic and life pressures and various demands.Local government should pay more attention to increase farmers′ income and improve rural security system.展开更多
The problem of wild elephants, or human-elephant conflict (HEC), influences the daily life of local communities and hinders the conservation of wild elephants.The perception and attitudes of local communities who inha...The problem of wild elephants, or human-elephant conflict (HEC), influences the daily life of local communities and hinders the conservation of wild elephants.The perception and attitudes of local communities who inhabited the frontiers between human activities and wild elephant movement are important to the mitigation of the HEC and conservation of wild elephants. To analyze the perception and attitudes of local communities, the Participatory Rural Appraisal (PRA) was used in the investigation of 423 interviewees from 22 villages in Xishuangbanna from July 2009 to February 2010. The results indicated that local communities had their views on the elephant-related problems. In field survey, we found that 66.5% of interviewees were willing to support, participate in, and assist in the conservation of wild elephants;33.5% of interviewees were opposed or indifferent to such conservation, because their livelihoods and even their lives were endangered by wild elephants. These views and attitudes were influenced by local communities′perception of HEC, education level, gender and self-interest. Therefore, it is necessary to analyze the diverse views among local communities and balance profits and costs in addressing HEC.展开更多
Infectious conjunctivitis is no longer a common eye disease in cities and developed areas, but in remote mountainous regions of China where living conditions are relatively under-developed, the occurrence of infectiou...Infectious conjunctivitis is no longer a common eye disease in cities and developed areas, but in remote mountainous regions of China where living conditions are relatively under-developed, the occurrence of infectious conjunctivitis remains a public health issue. Here, we evaluate the ratio of infectious conjunctivitis among primary school students in the rural areas of Xunhua, Huangyuan, and Huzhu Counties in the Qinghai province of China, and report the microorganisms involved in causing infection. Of the 765 eligible primary school students, 694 participated to this study(a response rateof 90.7%), 381 boys and 313 girls, with a mean age of 7.52 years(range 7–9 years). A clinical diagnosis of infectious conjunctivitis was returned for 238 of the 694 children examined. The ratio of infectious conjunctivitis in Xunhua County(46.64%) was higher compared to that in Huangyuan(26.67%; P=0.03) and Huzhu Counties(23.61%; P=0.02). The leading cause of conjunctivitis was bacterial, followed by chlamydial and viral. Our results show that there is a high ratio of infectious conjunctivitis among rural primary school students in Qinghai province.展开更多
OBJECTIVE: To provide survival estimates of people living with human immunodeficiency virus(PLHIV) after treatment with Traditional Chinese Medicine(TCM) in rural China, to identify the prognostic factors at enrollmen...OBJECTIVE: To provide survival estimates of people living with human immunodeficiency virus(PLHIV) after treatment with Traditional Chinese Medicine(TCM) in rural China, to identify the prognostic factors at enrollment, and to explore the effectiveness of TCM intreating PLHIV.METHODS: PLHIV who enrolled in national TCM HIV treatment trial program in October 2004 were analyzed in this study and followed up to October 2010. Survival time was estimated by the Kaplan-Meier curve and hazard ratios, and identifying prognostic factors were computed through Cox proportional hazard models.RESULTS:A total of 1666 PLHIV were included with 102 591 person-months of follow-up. Overall, 312(18.7%) patients died. The total mortality rate over the study period was 3.6 per 100 person-years,which was lower than the worldwide rate. The cumulative survival rate was 95.9% at 1 year[95% confidence interval(CI)(94.8-96.8)] and 80.4% at 6years [95% CI(78.4-82.3)]. Elevated death risks emerged among males, older individuals, and thosewithlowerCD4+T-cellcounts.CONCLUSION: TCM could increase survival and lengthen the life span of PLHIV in Henan province of China, as shown by our retrospective cohort study. Factors such as sex, age, education, and CD4+ T-cell counts correlated to survival. However,retrospective cohorts bias the data, so more prospective studies should be performed to confirm our primary results.展开更多
基金Supported by a grant from International Digestive Cancer Alliance and Peking University School of Oncology
文摘AIM： To compare the one-day quadruple therapy with a standard 7-d triple therapy for H pylori eradication in a rural population of China. METHODS： A total of 396 patients with 13C-urea breath test positive for H pylori were assigned into two groups： 239 patients received one-day quadruple therapy （amoxicillin 2000 mg qid; metronidazole 500 mg qid; bismuth citrate 900 mg qid and lansoprazole 60 mg once daily） and 157 patients received 7-d standard triple therapy （amoxicillin 1000 mg bid; clarithromycin 500 mg bid and lansoprazole 30 mg bid）. All the patients underwent a 13C-UBT to assess the eradication of Hpylori infection six weeks after treatment. RESULTS： Two hundred and twenty-nine patients completed the one-day therapy （95.8%） and 148 patients completed the 7-d therapy （94.2%）. The oneday therapy eradicated H pylori infection in 64 patients （27.95%）. In contrast, 103 patients （69.59%） were Hpylori negative after the 7-d therapy （P 〈 0.01）. CONCLUSION： This pilot study suggests there is no beneficial effect of the one-day therapy in treatment ofHpylori infection compared with the 7-d standard therapy.
基金Under the auspices of National Natural Science Foundation of China(No.40971051)
文摘China is experiencing a fast process of farmland conversion which is conducted mainly by local governments to fuel economic development.Social tension is aroused and policy makers take great concerns on coordinating interests among different stakeholders,especially for increasing farmers′ interest.The purpose of this study is to get some insights related to land acquisition institution by exploring farmers′ perception to farmland conversion.Participatory Rural Appraisal(PRA) was applied for the investigation in peri-urban area,of Xining City,Qinghai Province,China.The total of 519 householders from 15 villages completed valid questionnaire survey from July to November,2012.The results indicate that farmland conversion has several impacts on farmers′ life.Most farmers are gradually adapting to city life.Higher living expenses and more income are perceived by farmers with average score of 4.21 and 2.69,respectively.The average scores of 2.38 and 2.46 are for improvement of life security and more job opportunities.Farmers expect to get some stable ways of compensation in addition to lump-sum compensation in cash.Stable subsidies every year and obtaining same number of land received strong proposal.And these two options are cited by 49.6% and 43.9% of respondents.Farmland conversion brings about cleaner living condition and more amenities,but lower air visibility and drier air.Results reflect landless farmers′ economic and life pressures and various demands.Local government should pay more attention to increase farmers′ income and improve rural security system.
基金Under the auspices of National Natural Science Foundation of China(No.30870431)
文摘The problem of wild elephants, or human-elephant conflict (HEC), influences the daily life of local communities and hinders the conservation of wild elephants.The perception and attitudes of local communities who inhabited the frontiers between human activities and wild elephant movement are important to the mitigation of the HEC and conservation of wild elephants. To analyze the perception and attitudes of local communities, the Participatory Rural Appraisal (PRA) was used in the investigation of 423 interviewees from 22 villages in Xishuangbanna from July 2009 to February 2010. The results indicated that local communities had their views on the elephant-related problems. In field survey, we found that 66.5% of interviewees were willing to support, participate in, and assist in the conservation of wild elephants;33.5% of interviewees were opposed or indifferent to such conservation, because their livelihoods and even their lives were endangered by wild elephants. These views and attitudes were influenced by local communities′perception of HEC, education level, gender and self-interest. Therefore, it is necessary to analyze the diverse views among local communities and balance profits and costs in addressing HEC.
基金supported by National Natural Science Foundation of China (81470607)
文摘Infectious conjunctivitis is no longer a common eye disease in cities and developed areas, but in remote mountainous regions of China where living conditions are relatively under-developed, the occurrence of infectious conjunctivitis remains a public health issue. Here, we evaluate the ratio of infectious conjunctivitis among primary school students in the rural areas of Xunhua, Huangyuan, and Huzhu Counties in the Qinghai province of China, and report the microorganisms involved in causing infection. Of the 765 eligible primary school students, 694 participated to this study(a response rateof 90.7%), 381 boys and 313 girls, with a mean age of 7.52 years(range 7–9 years). A clinical diagnosis of infectious conjunctivitis was returned for 238 of the 694 children examined. The ratio of infectious conjunctivitis in Xunhua County(46.64%) was higher compared to that in Huangyuan(26.67%; P=0.03) and Huzhu Counties(23.61%; P=0.02). The leading cause of conjunctivitis was bacterial, followed by chlamydial and viral. Our results show that there is a high ratio of infectious conjunctivitis among rural primary school students in Qinghai province.
基金Supported by Research Project for Practice Development of National Traditional Chinese Medicine Clinical Research Bases(No.JDZX2012023)Henan province colleges and universities key youth teachers scheme(No.2013GGJS-095)+1 种基金National Special Science and Technology Program on Major Infectious Diseases(No.2012ZX10005010-001)China Academy of Traditional Chinese Medicine Item(No.ZZ060813)
文摘OBJECTIVE: To provide survival estimates of people living with human immunodeficiency virus(PLHIV) after treatment with Traditional Chinese Medicine(TCM) in rural China, to identify the prognostic factors at enrollment, and to explore the effectiveness of TCM intreating PLHIV.METHODS: PLHIV who enrolled in national TCM HIV treatment trial program in October 2004 were analyzed in this study and followed up to October 2010. Survival time was estimated by the Kaplan-Meier curve and hazard ratios, and identifying prognostic factors were computed through Cox proportional hazard models.RESULTS:A total of 1666 PLHIV were included with 102 591 person-months of follow-up. Overall, 312(18.7%) patients died. The total mortality rate over the study period was 3.6 per 100 person-years,which was lower than the worldwide rate. The cumulative survival rate was 95.9% at 1 year[95% confidence interval(CI)(94.8-96.8)] and 80.4% at 6years [95% CI(78.4-82.3)]. Elevated death risks emerged among males, older individuals, and thosewithlowerCD4+T-cellcounts.CONCLUSION: TCM could increase survival and lengthen the life span of PLHIV in Henan province of China, as shown by our retrospective cohort study. Factors such as sex, age, education, and CD4+ T-cell counts correlated to survival. However,retrospective cohorts bias the data, so more prospective studies should be performed to confirm our primary results.
