This study aimed to investigate the combined effects of nitrogen level (high and ordinary) and high temperature stress (37 ℃, 4 d) at the late panicle ini- tiation stage on yield, SPAD value and soluble sugar con...This study aimed to investigate the combined effects of nitrogen level (high and ordinary) and high temperature stress (37 ℃, 4 d) at the late panicle ini- tiation stage on yield, SPAD value and soluble sugar content of Ganxin 203, an early rice cultivar. The results showed that under both high and ordinary nitrogen levels, high temperature stress reduced the seed-setting rate, yield per stem, SPAD value and soluble sugar content of Ganxin 203; under both high and ordinary tem- peratures, high nitrogen level increased the seed-setting rate, yield per stem and soluble sugar content of Ganxin 203; the seed-setting rate, yield per stem and yield per plant of Ganxin 203 under high temperature and high nitrogen level were higher than those under high temperature and ordinary nitrogen level. It suggests that ap- propriate high nitrogen level contributes to weakening the negative effects of high temperature stress on rice yield.展开更多
A two-dimensional (2-D) polynomial regression model is set up to approximate the time-frequency response of slowly time-varying orthogonal frequency-division multiplexing (OFDM) systems. With this model the estima...A two-dimensional (2-D) polynomial regression model is set up to approximate the time-frequency response of slowly time-varying orthogonal frequency-division multiplexing (OFDM) systems. With this model the estimation of the OFDM time-frequency response is turned into the optimization of some time-invariant model parameters. A new algorithm based on the expectation-maximization (EM) method is proposed to obtain the maximum-likelihood (ML) estimation of the polynomial model parameters over the 2-D observed data. At the same time, in order to reduce the complexity and avoid the computation instability, a novel recursive approach (RPEMTO) is given to calculate the values of the parameters. It is further shown that this 2-D polynomial EM-based algorithm for time-varying OFDM (PEMTO) can be simplified mathematically to handle the one-dimensional sequential estimation. Simulations illustrate that the proposed algorithms achieve a lower bit error rate (BER) than other blind algorithms.展开更多
The performance loss of an approximately 3 dB signal-to-noise ratio is always paid with conventional differential detection compared to the related coherent detection. A new detection scheme consisting of two steps is...The performance loss of an approximately 3 dB signal-to-noise ratio is always paid with conventional differential detection compared to the related coherent detection. A new detection scheme consisting of two steps is proposed for the differential unitary space-time modulation (DUSTM) system. In the first step, the data sequence is estimated by conventional unitary space-time demodulation (DUSTD) and differentially encoded again to produce an initial estimate of the transmitted symbol stream. In the second step, the initial estimate of the symbol stream is utilized to initialize an expectation maximization (EM)-based iterative detector. In each iteration, the most recent detected symbol stream is employed to estimate the channel, which is then used to implement coherent sequence detection to refine the symbol stream. Simulation results show that the proposed detection scheme performs much better than the conventional DUSTD after several iterations.展开更多
Based on the 1961-2010 weather data from 65 meteorological stations in Heilongjiang Province, using the statistic software and GIS, the change characteristics of water budget, including the precipitation, reference ev...Based on the 1961-2010 weather data from 65 meteorological stations in Heilongjiang Province, using the statistic software and GIS, the change characteristics of water budget, including the precipitation, reference evapotranspiration and water budget in the whole year and the temperature-defined growing season, were analyzed. The results indicated that the both the precipitation during the whole year and that of during the temperature-defined growing season from 1961 to 2010 all decreased, while the annual reference evapotranspiration decreased, but the reference evapotranspiration during the temperature-defined growing season presented an increasing trend. The water resources were generally characterized by water deficit, especially in the beginning of 21 st .展开更多
An improved Gaussian mixture model (GMM)- based clustering method is proposed for the difficult case where the true distribution of data is against the assumed GMM. First, an improved model selection criterion, the ...An improved Gaussian mixture model (GMM)- based clustering method is proposed for the difficult case where the true distribution of data is against the assumed GMM. First, an improved model selection criterion, the completed likelihood minimum message length criterion, is derived. It can measure both the goodness-of-fit of the candidate GMM to the data and the goodness-of-partition of the data. Secondly, by utilizing the proposed criterion as the clustering objective function, an improved expectation- maximization (EM) algorithm is developed, which can avoid poor local optimal solutions compared to the standard EM algorithm for estimating the model parameters. The experimental results demonstrate that the proposed method can rectify the over-fitting tendency of representative GMM-based clustering approaches and can robustly provide more accurate clustering results.展开更多
The Fenghua River Bridge is a major structure on the highway between Hengzhang and Guojiachi, which is to be built with a four-span prestress concrete (PC) box girder and symmetrical cantilever castings. In this paper...The Fenghua River Bridge is a major structure on the highway between Hengzhang and Guojiachi, which is to be built with a four-span prestress concrete (PC) box girder and symmetrical cantilever castings. In this paper, a finite element method (FEM) model is set up to study the effects of concrete differential aging time on the construction phases of the Fenghua River Bridge by calculating the vertical displacement of the folding segment of the middle span and the longitudinal bending moment of Pier 12#. In the model, the girders are classified into 150 changing sections based on the desgn scheme, and their construction is to be carried in 16 phases respectively to build 12 blocks connected by a side folding segment and a middle folding segment, covered with a second dead load and in completion for 20 years. It is found that the internal forces and deformations of the concrete structures at the aging time of 60 d are quite different from those of 0 d aging time while the behaviors of the structures of 120 d aging time is nearly the same as those of 60 d aging time― the differences are so small that can be neglected, suggesting that the creep develops obviously about one month after the cement is hardened and the development fades later on.展开更多
Based on the monthly average SST and 850 hPa monthly average wind data,the seasonal,interannual and long-term variations in the eastern Indian Ocean warm pool(EIWP) and its relationship to the Indian Ocean Dipole(IOD)...Based on the monthly average SST and 850 hPa monthly average wind data,the seasonal,interannual and long-term variations in the eastern Indian Ocean warm pool(EIWP) and its relationship to the Indian Ocean Dipole(IOD),and its response to the wind over the Indian Ocean are analyzed in this study.The results show that the distribution range,boundary and area of the EIWP exhibited obviously seasonal and interannual variations associated with the ENSO cycles.Further analysis suggests that the EIWP had obvious long-term trend in its bound edge and area,which indicated the EIWP migrated westwards by about 14 longitudes for its west edge,southwards by about 5 latitudes for its south edge and increased by 3.52×106 km2 for its area,respectively,from 1950 to 2002.The correlation and composite analyses show that the anomalous westward and northward displacements of the EIWP caused by the easterly wind anomaly and the southerly wind anomaly over the eastern equatorial Indian Ocean played an important and direct role in the formation of the IOD.展开更多
The global long-term sea level trend is obtained from the analysis of tide gauge data and TOPEX/Poseidon data. The linear trend of global mean sea level is highly non-uniform spatially, with an average rate of 2.2 mmy...The global long-term sea level trend is obtained from the analysis of tide gauge data and TOPEX/Poseidon data. The linear trend of global mean sea level is highly non-uniform spatially, with an average rate of 2.2 mmyear^-1 in T/P sea-level rise from October 1992 to September 2002. Sea level change due to temperature variation (the thermosteric sea level) is discussed. The results are compared with TOPEX/Poseidon altimeter data in the same temporal span at different spatial scales. It is indicated that the thermal effect accounts for 86% and 73% of the observed seasonal variability in the northern and southern hemispheres, respectively. The TOPEX/Poseidon observed sea level lags behind the TSL by 2 months in the zonal band of 40%-60% in both the northern and southern hemispheres. Systematic differences of about 1-2 cm between TOPEX/Poseidon observations and thermosteric sea level data are obtained. The potential causes tbr these differences include water exchange among the atmosphere, land, and oceans, and some possible deviations in thermosteric contribution estimates and geophysical corrections to the TOPEX/Poseidon data.展开更多
Using the method of Singular Spectrum Analysis (SSA), the evolution regularity of tropical cyclo- nes landing in Guangdong are analyzed. The main periods of yearly topical cyclones landing in Guangdong are found at 8 ...Using the method of Singular Spectrum Analysis (SSA), the evolution regularity of tropical cyclo- nes landing in Guangdong are analyzed. The main periods of yearly topical cyclones landing in Guangdong are found at 8 and quasi-3 years, and in the west of Pearl River Mouth are 12 and quasi-2 years to the west of Pearl River Mouth. The northwest Pacific that topical cyclones are generated is divided into 8 areas, and the SeaSur- face Temperature (SST) in each area is analyzed using SSA. The main periods of NINO-west are 8 and 3 years, and those of the warm pool are 12 and 2 years, respectively. This may be the physical reason for the generation tropical cyclones landing in Guangdong. By combining the Maximum Entropy Method (MEM) with SSA (SSA- MEM), the yearly variation trend of tropical cyclones landing in Guangdong and the Pearl River Mouth are force- ast, and the results are good. The method can be used in operational short-range climate forecast.展开更多
Searching for more potent and less toxic HMBA related agents. Methods. Human erythroleukemia cell K562, murine erythroleukemia cell (MEL) and its sub line MEL DS19 were used as target cells to select a cell line which...Searching for more potent and less toxic HMBA related agents. Methods. Human erythroleukemia cell K562, murine erythroleukemia cell (MEL) and its sub line MEL DS19 were used as target cells to select a cell line which is the most sensitive to HMBA, then analyzed the activity of inducing differentiati on of two new designed HMBA derivatives: HMBPA [hexamethylenebi (3 pyridin) ami de] and Co HDTA (ethylenediaminetetra acetic acid cobalt) using cell biology, c ytochemical and molecular biology techniques. Results. We found that the MEL DS19 cells were most sensitive to HMBA (benzidine positive, B+~76%). Co HDTA can inhibit the growth of MEL DS19, but induces differentiation just in a small population (B+ 2%~4.5%). Between 0.02~5μmo l/L, HMBPA induces 3%~8% cells committed to differentiation with little inhib ition of cell proliferation. 1μmol/L HMBPA and 2mmol/L HMBA together, can obvio usly increase the percentage of differentiated cell (B+~ 72%), inhibit DNA sy nthesis and accelerate β globin transcription. Conclusion. The new HMBA derivatives may provide potential cancer differentiatio n inducers.展开更多
Objective The present study aims to identify the clinicopathologic factors predictive of lymph node metastasis(LNM) in poorly differentiated early gastric cancer(EGC) and to expand the possibility of using laparoscopi...Objective The present study aims to identify the clinicopathologic factors predictive of lymph node metastasis(LNM) in poorly differentiated early gastric cancer(EGC) and to expand the possibility of using laparoscopic surgery for the treatment of poorly differentiated EGC. Methods Data from 70 cases of poorly differentiated EGC treated with surgery were collected.The association between clinicopathologic factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results Univariate analysis showed that tumor size,depth of invasion,and lymphatic vessel involvement(LVI) were the significant and independent risk factors for LNM(all P<0.05).The LNM rates were 6.9%,45.5%,and 60.0%,respectively.There was no LNM in 25 patients without the above three risk factors. Conclusions Laparoscopic surgery is a sufficient treatment for intramucosal poorly differentiated EGC if the tumor is less than or equal to 2.0 cm in size and when LVI is absent upon postoperative histological examination.展开更多
Intercellular communication of notochord cells during their differentiation was studied by microinjection of a fluorescent dye, Lucifer Yellow. Close correlation existed between the incidences of dye coupling and quan...Intercellular communication of notochord cells during their differentiation was studied by microinjection of a fluorescent dye, Lucifer Yellow. Close correlation existed between the incidences of dye coupling and quantitative evaluation of gap junctions. High incidences of dye coupling and of gap junctions occurred at a stage when notochord cells were active in the change of cell shape and cell arrangement. With the subsidence of cell movements, both dye coupling and gap junctions were reduced to lower levels. It was, therefore, suggested that intercellular communication via gap junctions played an important role in the coordination of notochord cell movements.Gap junctions of altered configuration occurred in notochord cells in late tailbud stage. The comparison of incidences of dye coupling at this stage with those at other stages strongly suggested that the gap junctions of altered configuration functioned just as those of generalized type.展开更多
With the series of annual and seasonal temperature during 1957 – 2001 in Dongguan, Guangdong, the statistical characteristic and power spectrum and secular trend and sudden change phenomena are computed in this paper...With the series of annual and seasonal temperature during 1957 – 2001 in Dongguan, Guangdong, the statistical characteristic and power spectrum and secular trend and sudden change phenomena are computed in this paper. From the results it is known that (1) the temperatures have obvious characteristics of monsoon climate but do not have normal distribution, showing biased distribution of high or low kurtosis; (2) over the recent half- century, the temperatures tend to rise, specially in the last 10 years, in which mean temperature have quickly ascended by about 1.5°C, and except for the spring, there were sudden change of seasonal temperature rising from the 1980’s to 1990’s, which really reflected the influence of developing and opening and urbanization on Dongguan temperature; (3) except for the spring, the temperature of other seasons show some oscillatory periods in Dongguan and some of them also include long-term variation trends.展开更多
Hydration products and morphology characteristics of C3A (tricalcium aluminate)-CaCO3-H2O system were studied by means of XRD, DSC, FTIR spectrum analysis and SEM. The results indicate that, the new phases, i.e., C3...Hydration products and morphology characteristics of C3A (tricalcium aluminate)-CaCO3-H2O system were studied by means of XRD, DSC, FTIR spectrum analysis and SEM. The results indicate that, the new phases, i.e., C3A·0.5CaCO3·0.5Ca(OH)2·11.5H2O and C3A·CaCO3·11H2O are found in this system due to the activity of CaC03; the formation of C4AH13 and C2AH8 is prohibited and the generation of C3AH6 is delayed in the early hydration process. C3A·0.5CaCO3·0.5Ca(OH)2.11.5HEO is not stable and will be totally transferred within 24 h; C3A·CaCO3.11H2O exists stably once formation, and its flake-like crystalline phases in the early hydration transform to long rod shape, and to finally fine-needle at 28 d.展开更多
The paper deals with some questions of important aspects of food safety and application of principles of food physics in the food sector. Food production and processing of quality food and safe food are today of prima...The paper deals with some questions of important aspects of food safety and application of principles of food physics in the food sector. Food production and processing of quality food and safe food are today of primary importance. Food production is based on the principles of Good Agricultural Practice (GAP), Good Manufactoring Practice (GMP) and Good Hygiene Practice (GHP). Recently, the industrial food processing is focused dominantly on the quality, and one of the basic requirements of the quality is the safety. There are different methods and techniques to produce safe food. The up-to-date food technologies and quality measurements (quality control and quality assurance) involve the application of different physical methods, e.g., high pressure, pulsing electrical field, nondestructive techniques, e.g., nuclear magnetic resonance (NMR), near infrared reflectance, near infrared transmittance (NIR-NIT), photo acoustic spectroscopy (PAS) and instrumental neutron activation analysis (INAA) for chemical composition determination, radiation techniques, nanofiltration and reverse osmosis (RO) as well. Using ionizing radiation (nuclear methods) and non-ionizing radiation technologies, it is possible to fulfill a lot of expectations: decrease of microbial contamination, improve of sensory properties, increase of storability, etc..展开更多
Correlations among free radicals, apparent activation energy, and functional groups during lowtemperature oxidation of Jurassic coal in Northern Shaanxi were investigated by examining three coal samples collected from...Correlations among free radicals, apparent activation energy, and functional groups during lowtemperature oxidation of Jurassic coal in Northern Shaanxi were investigated by examining three coal samples collected from the Ningtiaota, Jianxin, and Shigetai coal mines. Free radical concentrations at less than 120 ℃ were investigated by electron spin resonance experiments while the thermogravimetric experiments were conducted to analyze apparent activation energies. In addition, Fourier transform infrared spectroscopy was employed to study the spectrum of functional groups generated in coal. The results indicated that, in decreasing order, the apparent activation energies were Shigetai 〉Jianxin 〉 Ningtiaota, indicating that, from 50 to 120 ℃, the Ningtiaota coal sample most easily absorbed and reacted with oxygen while the most resistant was the Shigetai coal sample. Free radical concentrations and line heights increased with increased temperature, and the line width and Lande factor showed irregular fluctuations. Functional group variations were different among these coals, and the phenol and alcohol-associated OHs, carboxyls, and aromatic ring double bonds might have had a major impact on free radical concentrations. These results were meaningful for better consideration and management of coal oxidation at low temperatures.展开更多
Seasonal variation of biochemical components in clam(Saxidomus purpuratus Sowerby 1852) was investigated from March 2012 to February 2013 in relation to environmental condition of Sanggou Bay and the reproductive cycl...Seasonal variation of biochemical components in clam(Saxidomus purpuratus Sowerby 1852) was investigated from March 2012 to February 2013 in relation to environmental condition of Sanggou Bay and the reproductive cycle of clam.According to the histological analysis,the reproductive cycle of S.purpuratus includes two distinctive phases:a total spent and inactive stage from November to January,and a gametogenesis stage,including ripeness and spawning,during the rest of the year.Gametes were generated at a low temperature(2.1℃) in February.Spawning took place once a year from June to October.The massive spawning occurred in August when the highest water temperature and chlorophyll a level could be observed.The key biochemical components(glycogen,protein and lipid) in five tissues(gonad,foot,mantle,siphon and adductor muscle) were analyzed.The glycogen content was high before gametogenesis,and decreased significantly during the gonad development in the gonad,mantle and foot of both females and males,suggesting that glycogen was an important energy source for gonad development.The protein and lipid contents increased in the ovary during the gonad development,demonstrating that they are the major organic components of oocytes.The lipid and protein contents decreased in the testis,implying that they can provide energy and material for spermatogenesis.The results also showed that protein stored in the mantle and foot could support the reproduction after the glycogen was depleted.展开更多
Xiashu loess strata are widely distributed along the middle-lower reaches of the Yangtze River in East China with the stratum near Nanjing,Jiangsu Province being typical.The cyclic variability of the stratum was inves...Xiashu loess strata are widely distributed along the middle-lower reaches of the Yangtze River in East China with the stratum near Nanjing,Jiangsu Province being typical.The cyclic variability of the stratum was investigated through comparison of geological features,chemical composition,and swelling-shrinkage properties between the loess and the paleosol layers.Based on the investigation of such a cyclic variability,soil behavior associated with the unsaturated state of the Xiashu loess stratum and its usefulness for geotechnical design and construction in the Nanjing area was analyzed. The stratum consisted of two types of cyclically alternating soil layers,namely the loess and the paleosol layers,which was the major cause for its cyclic variability.The loess and the paleosol layers were formed in different sedimentary environments.In order to avoid detrimental results from the differential engineering properties between them,this study suggested for the practitioners the importance of inspecting the variation of water content and controlling the downward net fluxes during geotechnical construction in the Nanjing area.展开更多
AIM: To investigate the prognostic significance of phosphatase regenerating liver 3 (PRL-3) protein expression in gastric cancer.METHODS: PRL-3 expression in paraffin-embedded tumor specimens from 293 patients wit...AIM: To investigate the prognostic significance of phosphatase regenerating liver 3 (PRL-3) protein expression in gastric cancer.METHODS: PRL-3 expression in paraffin-embedded tumor specimens from 293 patients with gastric cancer was studied retrospectively by immunohistochemistry. Nonoclonal antibody specifically against PRL-3, 3B6, was obtained with hybridoma technique.RESULTS: Positive PRL-3 expression was detected in 43.3% (227 of 293) of gastric cancer cases. High expression of PRL-3 was positively correlated with tumor size, depth of invasion, vascular/lymphatic invasion, lymph node metastasis, high TNM stage and tumor recurrence. Patients with positive PRL-3 expression had a significantly lower 5-year survival rate than those with negative expression (28.3% vs 52.9%, P 〈 0.0001). Patients who received curative surgery, and with positive PRL-3 expression had a significant shorter overall survival and disease-free disadvantage over patients with negative expression (hazard ratio of 16.7 and 16.6, respectively; P 〈 0.0001 for both). Multivariate analysis revealed that PRL-3 expression was an independent prognostic indicator for overall and disease-free survival of gastric cancer patients, particularly for survival in TNM stage Ⅲ patients. CONCLUSION: PRL-3 expression is a new independent prognostic indicator to predict the potential of recurrence and survival in patients with gastric cancer at the time of tumor resection,展开更多
基金Supported by Special Scientific Research Fund of Meteorological Public Welfare Profession of China(GYHY201406025GYHY201006025)+2 种基金Special Fund for Agroscientific Research in the Public Interest of China(201403002)Young Talent Project of China Meteorological AdministrationJiangxi"555"Ganpo Yingcai Project~~
文摘This study aimed to investigate the combined effects of nitrogen level (high and ordinary) and high temperature stress (37 ℃, 4 d) at the late panicle ini- tiation stage on yield, SPAD value and soluble sugar content of Ganxin 203, an early rice cultivar. The results showed that under both high and ordinary nitrogen levels, high temperature stress reduced the seed-setting rate, yield per stem, SPAD value and soluble sugar content of Ganxin 203; under both high and ordinary tem- peratures, high nitrogen level increased the seed-setting rate, yield per stem and soluble sugar content of Ganxin 203; the seed-setting rate, yield per stem and yield per plant of Ganxin 203 under high temperature and high nitrogen level were higher than those under high temperature and ordinary nitrogen level. It suggests that ap- propriate high nitrogen level contributes to weakening the negative effects of high temperature stress on rice yield.
基金The National Natural Science Foundation of China(No60472026)
文摘A two-dimensional (2-D) polynomial regression model is set up to approximate the time-frequency response of slowly time-varying orthogonal frequency-division multiplexing (OFDM) systems. With this model the estimation of the OFDM time-frequency response is turned into the optimization of some time-invariant model parameters. A new algorithm based on the expectation-maximization (EM) method is proposed to obtain the maximum-likelihood (ML) estimation of the polynomial model parameters over the 2-D observed data. At the same time, in order to reduce the complexity and avoid the computation instability, a novel recursive approach (RPEMTO) is given to calculate the values of the parameters. It is further shown that this 2-D polynomial EM-based algorithm for time-varying OFDM (PEMTO) can be simplified mathematically to handle the one-dimensional sequential estimation. Simulations illustrate that the proposed algorithms achieve a lower bit error rate (BER) than other blind algorithms.
基金The National Natural Science Foundation of China(No60572072,60496311)the National High Technology Research and Development Program of China (863Program) (No2006AA01Z264)+1 种基金the National Basic Research Program of China (973Program) (No2007CB310603)the PhD Programs Foundation of Ministry of Educa-tion of China (No20060286016)
文摘The performance loss of an approximately 3 dB signal-to-noise ratio is always paid with conventional differential detection compared to the related coherent detection. A new detection scheme consisting of two steps is proposed for the differential unitary space-time modulation (DUSTM) system. In the first step, the data sequence is estimated by conventional unitary space-time demodulation (DUSTD) and differentially encoded again to produce an initial estimate of the transmitted symbol stream. In the second step, the initial estimate of the symbol stream is utilized to initialize an expectation maximization (EM)-based iterative detector. In each iteration, the most recent detected symbol stream is employed to estimate the channel, which is then used to implement coherent sequence detection to refine the symbol stream. Simulation results show that the proposed detection scheme performs much better than the conventional DUSTD after several iterations.
基金Supported by the Special Fund for Meteorological-Scientific Research in the Public Interest(GYHY201106026,GYHY200906021,GYHY200706030)the Special Fund for Climate Changes of China Meteorological Administration(CCSF-09-13)~~
文摘Based on the 1961-2010 weather data from 65 meteorological stations in Heilongjiang Province, using the statistic software and GIS, the change characteristics of water budget, including the precipitation, reference evapotranspiration and water budget in the whole year and the temperature-defined growing season, were analyzed. The results indicated that the both the precipitation during the whole year and that of during the temperature-defined growing season from 1961 to 2010 all decreased, while the annual reference evapotranspiration decreased, but the reference evapotranspiration during the temperature-defined growing season presented an increasing trend. The water resources were generally characterized by water deficit, especially in the beginning of 21 st .
基金The National Natural Science Foundation of China(No.61105048,60972165)the Doctoral Fund of Ministry of Education of China(No.20110092120034)+2 种基金the Natural Science Foundation of Jiangsu Province(No.BK2010240)the Technology Foundation for Selected Overseas Chinese Scholar,Ministry of Human Resources and Social Security of China(No.6722000008)the Open Fund of Jiangsu Province Key Laboratory for Remote Measuring and Control(No.YCCK201005)
文摘An improved Gaussian mixture model (GMM)- based clustering method is proposed for the difficult case where the true distribution of data is against the assumed GMM. First, an improved model selection criterion, the completed likelihood minimum message length criterion, is derived. It can measure both the goodness-of-fit of the candidate GMM to the data and the goodness-of-partition of the data. Secondly, by utilizing the proposed criterion as the clustering objective function, an improved expectation- maximization (EM) algorithm is developed, which can avoid poor local optimal solutions compared to the standard EM algorithm for estimating the model parameters. The experimental results demonstrate that the proposed method can rectify the over-fitting tendency of representative GMM-based clustering approaches and can robustly provide more accurate clustering results.
文摘The Fenghua River Bridge is a major structure on the highway between Hengzhang and Guojiachi, which is to be built with a four-span prestress concrete (PC) box girder and symmetrical cantilever castings. In this paper, a finite element method (FEM) model is set up to study the effects of concrete differential aging time on the construction phases of the Fenghua River Bridge by calculating the vertical displacement of the folding segment of the middle span and the longitudinal bending moment of Pier 12#. In the model, the girders are classified into 150 changing sections based on the desgn scheme, and their construction is to be carried in 16 phases respectively to build 12 blocks connected by a side folding segment and a middle folding segment, covered with a second dead load and in completion for 20 years. It is found that the internal forces and deformations of the concrete structures at the aging time of 60 d are quite different from those of 0 d aging time while the behaviors of the structures of 120 d aging time is nearly the same as those of 60 d aging time― the differences are so small that can be neglected, suggesting that the creep develops obviously about one month after the cement is hardened and the development fades later on.
基金Supported by the National Key Basic Research Development Program of China (973 Program)(No 2006CB403606)the Knowledge Innovation Program of Chinese Academy of Sciences (KZCX1-YW-12)the National Natural Science Foundation of China (No 40306006)
文摘Based on the monthly average SST and 850 hPa monthly average wind data,the seasonal,interannual and long-term variations in the eastern Indian Ocean warm pool(EIWP) and its relationship to the Indian Ocean Dipole(IOD),and its response to the wind over the Indian Ocean are analyzed in this study.The results show that the distribution range,boundary and area of the EIWP exhibited obviously seasonal and interannual variations associated with the ENSO cycles.Further analysis suggests that the EIWP had obvious long-term trend in its bound edge and area,which indicated the EIWP migrated westwards by about 14 longitudes for its west edge,southwards by about 5 latitudes for its south edge and increased by 3.52×106 km2 for its area,respectively,from 1950 to 2002.The correlation and composite analyses show that the anomalous westward and northward displacements of the EIWP caused by the easterly wind anomaly and the southerly wind anomaly over the eastern equatorial Indian Ocean played an important and direct role in the formation of the IOD.
基金supported by the NSFC projects (Nos. 40376005, 40676013, 40506006 and 40676015)the SRFDP project (No. 20060423014)+1 种基金NCET-04-0646 Key Scientific Research Program (No. 2007CB411807)National Key Technology R&D Program (No. 2007BAC- 03A06-06)
文摘The global long-term sea level trend is obtained from the analysis of tide gauge data and TOPEX/Poseidon data. The linear trend of global mean sea level is highly non-uniform spatially, with an average rate of 2.2 mmyear^-1 in T/P sea-level rise from October 1992 to September 2002. Sea level change due to temperature variation (the thermosteric sea level) is discussed. The results are compared with TOPEX/Poseidon altimeter data in the same temporal span at different spatial scales. It is indicated that the thermal effect accounts for 86% and 73% of the observed seasonal variability in the northern and southern hemispheres, respectively. The TOPEX/Poseidon observed sea level lags behind the TSL by 2 months in the zonal band of 40%-60% in both the northern and southern hemispheres. Systematic differences of about 1-2 cm between TOPEX/Poseidon observations and thermosteric sea level data are obtained. The potential causes tbr these differences include water exchange among the atmosphere, land, and oceans, and some possible deviations in thermosteric contribution estimates and geophysical corrections to the TOPEX/Poseidon data.
基金Research on Short-Term Climate Systems--a key project in the 9th -five year economic de- velopment plan (96-908-05-07)
文摘Using the method of Singular Spectrum Analysis (SSA), the evolution regularity of tropical cyclo- nes landing in Guangdong are analyzed. The main periods of yearly topical cyclones landing in Guangdong are found at 8 and quasi-3 years, and in the west of Pearl River Mouth are 12 and quasi-2 years to the west of Pearl River Mouth. The northwest Pacific that topical cyclones are generated is divided into 8 areas, and the SeaSur- face Temperature (SST) in each area is analyzed using SSA. The main periods of NINO-west are 8 and 3 years, and those of the warm pool are 12 and 2 years, respectively. This may be the physical reason for the generation tropical cyclones landing in Guangdong. By combining the Maximum Entropy Method (MEM) with SSA (SSA- MEM), the yearly variation trend of tropical cyclones landing in Guangdong and the Pearl River Mouth are force- ast, and the results are good. The method can be used in operational short-range climate forecast.
文摘Searching for more potent and less toxic HMBA related agents. Methods. Human erythroleukemia cell K562, murine erythroleukemia cell (MEL) and its sub line MEL DS19 were used as target cells to select a cell line which is the most sensitive to HMBA, then analyzed the activity of inducing differentiati on of two new designed HMBA derivatives: HMBPA [hexamethylenebi (3 pyridin) ami de] and Co HDTA (ethylenediaminetetra acetic acid cobalt) using cell biology, c ytochemical and molecular biology techniques. Results. We found that the MEL DS19 cells were most sensitive to HMBA (benzidine positive, B+~76%). Co HDTA can inhibit the growth of MEL DS19, but induces differentiation just in a small population (B+ 2%~4.5%). Between 0.02~5μmo l/L, HMBPA induces 3%~8% cells committed to differentiation with little inhib ition of cell proliferation. 1μmol/L HMBPA and 2mmol/L HMBA together, can obvio usly increase the percentage of differentiated cell (B+~ 72%), inhibit DNA sy nthesis and accelerate β globin transcription. Conclusion. The new HMBA derivatives may provide potential cancer differentiatio n inducers.
基金supported by the Science Foundation of Xingtai City,China(No.20102025-2)
文摘Objective The present study aims to identify the clinicopathologic factors predictive of lymph node metastasis(LNM) in poorly differentiated early gastric cancer(EGC) and to expand the possibility of using laparoscopic surgery for the treatment of poorly differentiated EGC. Methods Data from 70 cases of poorly differentiated EGC treated with surgery were collected.The association between clinicopathologic factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results Univariate analysis showed that tumor size,depth of invasion,and lymphatic vessel involvement(LVI) were the significant and independent risk factors for LNM(all P<0.05).The LNM rates were 6.9%,45.5%,and 60.0%,respectively.There was no LNM in 25 patients without the above three risk factors. Conclusions Laparoscopic surgery is a sufficient treatment for intramucosal poorly differentiated EGC if the tumor is less than or equal to 2.0 cm in size and when LVI is absent upon postoperative histological examination.
文摘Intercellular communication of notochord cells during their differentiation was studied by microinjection of a fluorescent dye, Lucifer Yellow. Close correlation existed between the incidences of dye coupling and quantitative evaluation of gap junctions. High incidences of dye coupling and of gap junctions occurred at a stage when notochord cells were active in the change of cell shape and cell arrangement. With the subsidence of cell movements, both dye coupling and gap junctions were reduced to lower levels. It was, therefore, suggested that intercellular communication via gap junctions played an important role in the coordination of notochord cell movements.Gap junctions of altered configuration occurred in notochord cells in late tailbud stage. The comparison of incidences of dye coupling at this stage with those at other stages strongly suggested that the gap junctions of altered configuration functioned just as those of generalized type.
文摘With the series of annual and seasonal temperature during 1957 – 2001 in Dongguan, Guangdong, the statistical characteristic and power spectrum and secular trend and sudden change phenomena are computed in this paper. From the results it is known that (1) the temperatures have obvious characteristics of monsoon climate but do not have normal distribution, showing biased distribution of high or low kurtosis; (2) over the recent half- century, the temperatures tend to rise, specially in the last 10 years, in which mean temperature have quickly ascended by about 1.5°C, and except for the spring, there were sudden change of seasonal temperature rising from the 1980’s to 1990’s, which really reflected the influence of developing and opening and urbanization on Dongguan temperature; (3) except for the spring, the temperature of other seasons show some oscillatory periods in Dongguan and some of them also include long-term variation trends.
基金Project(50678177) supported by by the National Natural Science Foundation of China
文摘Hydration products and morphology characteristics of C3A (tricalcium aluminate)-CaCO3-H2O system were studied by means of XRD, DSC, FTIR spectrum analysis and SEM. The results indicate that, the new phases, i.e., C3A·0.5CaCO3·0.5Ca(OH)2·11.5H2O and C3A·CaCO3·11H2O are found in this system due to the activity of CaC03; the formation of C4AH13 and C2AH8 is prohibited and the generation of C3AH6 is delayed in the early hydration process. C3A·0.5CaCO3·0.5Ca(OH)2.11.5HEO is not stable and will be totally transferred within 24 h; C3A·CaCO3.11H2O exists stably once formation, and its flake-like crystalline phases in the early hydration transform to long rod shape, and to finally fine-needle at 28 d.
文摘The paper deals with some questions of important aspects of food safety and application of principles of food physics in the food sector. Food production and processing of quality food and safe food are today of primary importance. Food production is based on the principles of Good Agricultural Practice (GAP), Good Manufactoring Practice (GMP) and Good Hygiene Practice (GHP). Recently, the industrial food processing is focused dominantly on the quality, and one of the basic requirements of the quality is the safety. There are different methods and techniques to produce safe food. The up-to-date food technologies and quality measurements (quality control and quality assurance) involve the application of different physical methods, e.g., high pressure, pulsing electrical field, nondestructive techniques, e.g., nuclear magnetic resonance (NMR), near infrared reflectance, near infrared transmittance (NIR-NIT), photo acoustic spectroscopy (PAS) and instrumental neutron activation analysis (INAA) for chemical composition determination, radiation techniques, nanofiltration and reverse osmosis (RO) as well. Using ionizing radiation (nuclear methods) and non-ionizing radiation technologies, it is possible to fulfill a lot of expectations: decrease of microbial contamination, improve of sensory properties, increase of storability, etc..
基金supported by the Key Projects of the National Natural Science Foundation of China (Nos. 51504187, 51774233, and 51704226)Shaanxi Province Industrial Science and Technology Research Project (No. 2016GY-192)the China Postdoctoral Science Foundation (No. 2016-M-590963)
文摘Correlations among free radicals, apparent activation energy, and functional groups during lowtemperature oxidation of Jurassic coal in Northern Shaanxi were investigated by examining three coal samples collected from the Ningtiaota, Jianxin, and Shigetai coal mines. Free radical concentrations at less than 120 ℃ were investigated by electron spin resonance experiments while the thermogravimetric experiments were conducted to analyze apparent activation energies. In addition, Fourier transform infrared spectroscopy was employed to study the spectrum of functional groups generated in coal. The results indicated that, in decreasing order, the apparent activation energies were Shigetai 〉Jianxin 〉 Ningtiaota, indicating that, from 50 to 120 ℃, the Ningtiaota coal sample most easily absorbed and reacted with oxygen while the most resistant was the Shigetai coal sample. Free radical concentrations and line heights increased with increased temperature, and the line width and Lande factor showed irregular fluctuations. Functional group variations were different among these coals, and the phenol and alcohol-associated OHs, carboxyls, and aromatic ring double bonds might have had a major impact on free radical concentrations. These results were meaningful for better consideration and management of coal oxidation at low temperatures.
基金supported by the grants from National Marine Public Welfare Research Program (201305005)Scientific and Technical Supporting Program (2011BA D13B01)National Natural Science Foundation of China (41276138)
文摘Seasonal variation of biochemical components in clam(Saxidomus purpuratus Sowerby 1852) was investigated from March 2012 to February 2013 in relation to environmental condition of Sanggou Bay and the reproductive cycle of clam.According to the histological analysis,the reproductive cycle of S.purpuratus includes two distinctive phases:a total spent and inactive stage from November to January,and a gametogenesis stage,including ripeness and spawning,during the rest of the year.Gametes were generated at a low temperature(2.1℃) in February.Spawning took place once a year from June to October.The massive spawning occurred in August when the highest water temperature and chlorophyll a level could be observed.The key biochemical components(glycogen,protein and lipid) in five tissues(gonad,foot,mantle,siphon and adductor muscle) were analyzed.The glycogen content was high before gametogenesis,and decreased significantly during the gonad development in the gonad,mantle and foot of both females and males,suggesting that glycogen was an important energy source for gonad development.The protein and lipid contents increased in the ovary during the gonad development,demonstrating that they are the major organic components of oocytes.The lipid and protein contents decreased in the testis,implying that they can provide energy and material for spermatogenesis.The results also showed that protein stored in the mantle and foot could support the reproduction after the glycogen was depleted.
基金Project supported by the Foundation for the Key Disciplines of Nanjing University of Technology.
文摘Xiashu loess strata are widely distributed along the middle-lower reaches of the Yangtze River in East China with the stratum near Nanjing,Jiangsu Province being typical.The cyclic variability of the stratum was investigated through comparison of geological features,chemical composition,and swelling-shrinkage properties between the loess and the paleosol layers.Based on the investigation of such a cyclic variability,soil behavior associated with the unsaturated state of the Xiashu loess stratum and its usefulness for geotechnical design and construction in the Nanjing area was analyzed. The stratum consisted of two types of cyclically alternating soil layers,namely the loess and the paleosol layers,which was the major cause for its cyclic variability.The loess and the paleosol layers were formed in different sedimentary environments.In order to avoid detrimental results from the differential engineering properties between them,this study suggested for the practitioners the importance of inspecting the variation of water content and controlling the downward net fluxes during geotechnical construction in the Nanjing area.
基金Supported by Grant for Key Technology Research and Development Program 2002BA711A06National Basic Research Priorities Program 973 Project 1998051203the Ministry of Science and Technology of China,and grant H020920030390,from the Beijing Science and Technology Commission
文摘AIM: To investigate the prognostic significance of phosphatase regenerating liver 3 (PRL-3) protein expression in gastric cancer.METHODS: PRL-3 expression in paraffin-embedded tumor specimens from 293 patients with gastric cancer was studied retrospectively by immunohistochemistry. Nonoclonal antibody specifically against PRL-3, 3B6, was obtained with hybridoma technique.RESULTS: Positive PRL-3 expression was detected in 43.3% (227 of 293) of gastric cancer cases. High expression of PRL-3 was positively correlated with tumor size, depth of invasion, vascular/lymphatic invasion, lymph node metastasis, high TNM stage and tumor recurrence. Patients with positive PRL-3 expression had a significantly lower 5-year survival rate than those with negative expression (28.3% vs 52.9%, P 〈 0.0001). Patients who received curative surgery, and with positive PRL-3 expression had a significant shorter overall survival and disease-free disadvantage over patients with negative expression (hazard ratio of 16.7 and 16.6, respectively; P 〈 0.0001 for both). Multivariate analysis revealed that PRL-3 expression was an independent prognostic indicator for overall and disease-free survival of gastric cancer patients, particularly for survival in TNM stage Ⅲ patients. CONCLUSION: PRL-3 expression is a new independent prognostic indicator to predict the potential of recurrence and survival in patients with gastric cancer at the time of tumor resection,