Alzheimer's disease is a multifactorial pathology, for which no cure is currently available. Nowadays, researchers are moving towards a new hypothesis of the onset of the illness, linking it to a metabolic impairment...Alzheimer's disease is a multifactorial pathology, for which no cure is currently available. Nowadays, researchers are moving towards a new hypothesis of the onset of the illness, linking it to a metabolic impairment, q-his innovative approach will lead to the identification of new targets for the preparation of new effective drugs. Peroxisome proliferator-activated receptors and their ligands are the ideal candidates to reach the necessary breakthrough to defeat this complicate disease.展开更多
In cognitive linguistics, metaphor acts as an important tool in cognition. This paper explores and exposes the value of metaphor in English teaching. Thus, metaphor, as a significant way of thinking, not only provides...In cognitive linguistics, metaphor acts as an important tool in cognition. This paper explores and exposes the value of metaphor in English teaching. Thus, metaphor, as a significant way of thinking, not only provides the new way for English teaching, but also proposes the viewpoint that language teaching is one of the fields for cultivating thinking ability and creativity.展开更多
This paper falls into the broad area of economic geography and economics of creativity,and it presents an alternative approach to explain why total factor productivity(TFP)growth is different across China′s regions.I...This paper falls into the broad area of economic geography and economics of creativity,and it presents an alternative approach to explain why total factor productivity(TFP)growth is different across China′s regions.It establishes an empirical model to estimate the spatial agglomeration effects of creative industries on regional TFP growth,using China′s provincial panel data during the period of 2003 to 2010.We found that the creative industries agglomeration(CIA)has significant and positive impact on regional TFP growth.The result also implies that the CIA can facilitate regional TFP growth through promoting regional innovation instead of improving regional efficiency.Therefore,we argue that policy makers should take some measures to retain and establish more creative zones.展开更多
The Green and Sustainable Chemistry Network (GSCN) has been promoting GSC technology development since 2000 in three major activities, holding the GSC symposium, running the GSC Awards, and providing the information...The Green and Sustainable Chemistry Network (GSCN) has been promoting GSC technology development since 2000 in three major activities, holding the GSC symposium, running the GSC Awards, and providing the information related to GSC in Japan. GSCN holds a vision to expand the philosophy of GSC not only to the domestic, but also to the global. As for a regional network in Asia and Oceania, we established the Asia-Oceania GSC Network, and we hope to expand the Network to all countries.展开更多
Method development has always been and will continue to be a core driving force of microbiome science, In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by...Method development has always been and will continue to be a core driving force of microbiome science, In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by three key changes in both ways of thinking and technological platforms: ① a shift from dissecting microbiota structure by sequencing to tracking microbiota state, function, and intercellular interaction via imaging; ② a shift from interrogating a consortium or population of cells to probing individual cells; and ③a shift from microbiome data analysis to microbiome data science. Some of the recent methoddevelopment efforts by Chinese microbiome scientists and their international collaborators that underlie these technological trends are highlighted here. It is our belief that the China Microbiome Initiative has the opportunity to deliver outstanding "Made-in-China" tools to the international research community, by building an ambitious, competitive, and collaborative program at the forefront of method development for microbiome science.展开更多
This study compares the subject matter appeared on traditional Thai textbooks and Japanese textbooks and analyzes how extension and integration sequence on Japanese textbooks evokes students' mathematical creativity....This study compares the subject matter appeared on traditional Thai textbooks and Japanese textbooks and analyzes how extension and integration sequence on Japanese textbooks evokes students' mathematical creativity. The data were collected from the series of four lessons in the fifth grade by teaching experiment methodology conducted following the professional development project implemented lesson study and open approach in Thailand. The results show that extension and integration sequence is an appropriate subject matter to generate lesson for problem-solving classroom. The sequence of lesson leads students to excitement, curiosity, confidence and intimacy in mathematics that are powerful effects of mathematical creativity. Students can produce the different and various ways to solve problems that indicate their divergent thinking.展开更多
After announcing the goal of building a moderately prosperous society in all respects by 2020, the Chinese leadership also called for a new path of industrialization, putting a premium on quality and new development c...After announcing the goal of building a moderately prosperous society in all respects by 2020, the Chinese leadership also called for a new path of industrialization, putting a premium on quality and new development concepts. Unlike traditional industrialization in the broad or narrow sense, new-type industrialization features synergy between primary, secondary, and tertiary industries, integration between traditional economy and the new economy, environmental protection, technology progress, and innovation. It represents an inclusive approach to industrial development. At the fundamental level, the success of China’s new-type industrialization can be attributed to China’s inclusive learning and innovations.展开更多
To conform to the college English teaching reform from English for General Purposes (EGP) to English for Academic Purposes (EAP) in the vital transfer era, the Foreign Language Department of Second Military Medical Un...To conform to the college English teaching reform from English for General Purposes (EGP) to English for Academic Purposes (EAP) in the vital transfer era, the Foreign Language Department of Second Military Medical University (SMMU) launched an English for Medical Academic Purpose (EMAP) curriculum with English Forum on Medical Humanities (EFMH), a project-based teaching practice. Based on Rogers' learner-centered humanistic teaching approach which emphasizes students' involvement and experiences in learning, EFMH puts students and their practice in a central place. After four-year exploration and operation, the Forum has developed from a small-scaled embryo into an internationalized, standardized and professionalized event, having produced fruitful outcomes. It is expected that the success of EFMH will provide inspiring experiences and enlightenments for higher medical education in terms of academic English teaching and teachers' responsibilities to foster high-quality medical students.展开更多
In this study, the characteristics of nanocellulose extracted from bleached softwood and hardwood pulps by formic acid hydrolysis followed by TEMPO-mediated oxidation were compared using transmission electron microsco...In this study, the characteristics of nanocellulose extracted from bleached softwood and hardwood pulps by formic acid hydrolysis followed by TEMPO-mediated oxidation were compared using transmission electron microscopy(TEM), atomic force microscopy(AFM), Fourier transform infrared analysis(FT-IR), X-ray diffraction(XRD), and thermal gravimetric analysis(TGA). The experimental results showed that the nanocellulose products derived from spruce pulp exhibited a relatively larger particle size, higher crystallinity, and higher thermal stability, compared with the corresponding products obtained from aspen pulp under the same conditions.Furthermore, the study helped establish that the properties of the nanocellulose products were highly dependent on the nature of the starting materials under identical processing conditions.展开更多
Nanocellulose(NC) has attracted much interest in the tissue engineering(TE) field because of its properties including biocompatibility,renewability, non-toxicity, functionality, and excellent mechanical performance. T...Nanocellulose(NC) has attracted much interest in the tissue engineering(TE) field because of its properties including biocompatibility,renewability, non-toxicity, functionality, and excellent mechanical performance. This review mainly focused on the advanced applications of NC-based composites in hard TE including cartilage TE, bone TE, and dental TE, illustrated the processing methods for synthesizing scaffolds including electrospinning, freeze-drying, and 3 D printing, reviewed the current status of hard TE, and presented perspective on the future of TE technology.展开更多
Cellulose nanocrystals (CNCs), a unique and promising natural material extracted from native cellulose, have attracted considerable attention owing to their physical properties and special surface chemistry. This...Cellulose nanocrystals (CNCs), a unique and promising natural material extracted from native cellulose, have attracted considerable attention owing to their physical properties and special surface chemistry. This review focuses on chemical conjugation strategies that can be used for preparation of ?uorescent-molecule labeled CNCs and the development of biomaterials. Furthermore, their application in the detection of metal ions and future development prospects are discussed. We hope to provide a clear view of the strategies for surface fluorescent modifcation of CNCs and their application in detection of metal ions.展开更多
A fuzzy integral based way of measurement assessment has been established by using linguistic varia-bles and combining fuzzy integral with hierarchy analysis for measurement of medium and small enterprises'product...A fuzzy integral based way of measurement assessment has been established by using linguistic varia-bles and combining fuzzy integral with hierarchy analysis for measurement of medium and small enterprises'product innovation. The conclusions drawn from analyses made with 20 medium and small enterprises providebases for governments to formulate applicable policies and for medium and small enterprises to enhance theirproduct innovation.展开更多
Focusing on the reform initiatives of Chinese Academy of Medical Sciences(CAMS) & Peking Union Medical College(PUMC) in medical scientific and technological innovation from perspectives of deepening the reform and...Focusing on the reform initiatives of Chinese Academy of Medical Sciences(CAMS) & Peking Union Medical College(PUMC) in medical scientific and technological innovation from perspectives of deepening the reform and optimizing the ecosystem of science and technology innovation,this article summarizes the highlights of CAMS & PUMC’s efforts in safeguarding people’ s health and promoting the Healthy China 2030 strategy through scientific and technological innovation in the fields including basic research,disease prevention and treatment,and medical technology in the past ten years.These achievements embody the endeavors and responsibility of CAMS& PUMC in realizing self-reliance and self-improvement of Chinese medical science and technology and highlight its contributions to the development of medical science and technology of China.展开更多
The project analyzes the student's participation in complementary activities such as Education Tutorial Program, Junior Company and Academic Center. These organizations have the goal to improve, expand and connect kn...The project analyzes the student's participation in complementary activities such as Education Tutorial Program, Junior Company and Academic Center. These organizations have the goal to improve, expand and connect knowledge learned during classes with several practical activities. They can provide a huge integration between the students and the professors in order to achieve better results in the pedagogical, structural and organizational parts of an engineering major degree. Therefore, the project goes through the impact of each entity in the student's life and the advantages to professional future, focusing the presence of these organizations in the Electrical Engineering Course of Federal University of Rio Grande do Norte.展开更多
Practice education is an important part of application-oriented higher education. Yet it poses many challenges when the design of practice education is questioned concerning whether it actually fulfills the education ...Practice education is an important part of application-oriented higher education. Yet it poses many challenges when the design of practice education is questioned concerning whether it actually fulfills the education purpose for high quality future professionals. This paper thus introduces an innovated "base"-driven model of practice education in Zhejiang University City College in China, with a purpose to provide empirical experiences that may be valuable for the decision-making of practice education design in higher education institutions. The paper progresses by examining the philosophy of its innovated model, discussing the framework, and further highlights a strategic consideration when designing practice education activities in higher education institutions.展开更多
The new media especially the use of mobile phone for information has a profound impact on contemporary university students' behavior, psychology, and way of thinking. This article will elaborate on the moral educatio...The new media especially the use of mobile phone for information has a profound impact on contemporary university students' behavior, psychology, and way of thinking. This article will elaborate on the moral education work with university students to explore innovative ideas and innovative approaches from the perspective of interpersonal communication, political science, and sociology under the new media environment. Then the article will put forward countermeasures and improvement strategies.展开更多
基金supported by Intervento cofinanziato dal Fondo di Sviluppo e Coesione 2007-2013–APQ Ricerca Regione Puglia "Programma regionale a sostegno della specializzazione intelligente e della sostenibilitàsociale ed ambientale-FutureInResearch".Project ID:I2PCTF6
文摘Alzheimer's disease is a multifactorial pathology, for which no cure is currently available. Nowadays, researchers are moving towards a new hypothesis of the onset of the illness, linking it to a metabolic impairment, q-his innovative approach will lead to the identification of new targets for the preparation of new effective drugs. Peroxisome proliferator-activated receptors and their ligands are the ideal candidates to reach the necessary breakthrough to defeat this complicate disease.
文摘In cognitive linguistics, metaphor acts as an important tool in cognition. This paper explores and exposes the value of metaphor in English teaching. Thus, metaphor, as a significant way of thinking, not only provides the new way for English teaching, but also proposes the viewpoint that language teaching is one of the fields for cultivating thinking ability and creativity.
基金Under the auspices of National Natural Science Foundation of China(No.71172213,71171183)Ministry of Educa-tion,Humanities and Social Sciences Project(No.09YJA630153,10YJA790260)+1 种基金National Social Science Foundation of China(No.08&ZD043)Australian Research Council,and Chinese Academy of Sciences(CAS)Special Grant for Postgraduate Research,Inno-vation and Practice
文摘This paper falls into the broad area of economic geography and economics of creativity,and it presents an alternative approach to explain why total factor productivity(TFP)growth is different across China′s regions.It establishes an empirical model to estimate the spatial agglomeration effects of creative industries on regional TFP growth,using China′s provincial panel data during the period of 2003 to 2010.We found that the creative industries agglomeration(CIA)has significant and positive impact on regional TFP growth.The result also implies that the CIA can facilitate regional TFP growth through promoting regional innovation instead of improving regional efficiency.Therefore,we argue that policy makers should take some measures to retain and establish more creative zones.
文摘The Green and Sustainable Chemistry Network (GSCN) has been promoting GSC technology development since 2000 in three major activities, holding the GSC symposium, running the GSC Awards, and providing the information related to GSC in Japan. GSCN holds a vision to expand the philosophy of GSC not only to the domestic, but also to the global. As for a regional network in Asia and Oceania, we established the Asia-Oceania GSC Network, and we hope to expand the Network to all countries.
基金We are grateful to the support from the National Natural Science Foundation of China (NSFC) (31425002, 91231205, 81430011, 61303161, 31470220, and 31327001), and the Frontier Science Research Program, the Soil-Microbe System Function and Regulation Program, and the Science and Technology Service Network Initiative (STS) from the Chinese Academy of Sciences (CAS).
文摘Method development has always been and will continue to be a core driving force of microbiome science, In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by three key changes in both ways of thinking and technological platforms: ① a shift from dissecting microbiota structure by sequencing to tracking microbiota state, function, and intercellular interaction via imaging; ② a shift from interrogating a consortium or population of cells to probing individual cells; and ③a shift from microbiome data analysis to microbiome data science. Some of the recent methoddevelopment efforts by Chinese microbiome scientists and their international collaborators that underlie these technological trends are highlighted here. It is our belief that the China Microbiome Initiative has the opportunity to deliver outstanding "Made-in-China" tools to the international research community, by building an ambitious, competitive, and collaborative program at the forefront of method development for microbiome science.
文摘This study compares the subject matter appeared on traditional Thai textbooks and Japanese textbooks and analyzes how extension and integration sequence on Japanese textbooks evokes students' mathematical creativity. The data were collected from the series of four lessons in the fifth grade by teaching experiment methodology conducted following the professional development project implemented lesson study and open approach in Thailand. The results show that extension and integration sequence is an appropriate subject matter to generate lesson for problem-solving classroom. The sequence of lesson leads students to excitement, curiosity, confidence and intimacy in mathematics that are powerful effects of mathematical creativity. Students can produce the different and various ways to solve problems that indicate their divergent thinking.
文摘After announcing the goal of building a moderately prosperous society in all respects by 2020, the Chinese leadership also called for a new path of industrialization, putting a premium on quality and new development concepts. Unlike traditional industrialization in the broad or narrow sense, new-type industrialization features synergy between primary, secondary, and tertiary industries, integration between traditional economy and the new economy, environmental protection, technology progress, and innovation. It represents an inclusive approach to industrial development. At the fundamental level, the success of China’s new-type industrialization can be attributed to China’s inclusive learning and innovations.
文摘To conform to the college English teaching reform from English for General Purposes (EGP) to English for Academic Purposes (EAP) in the vital transfer era, the Foreign Language Department of Second Military Medical University (SMMU) launched an English for Medical Academic Purpose (EMAP) curriculum with English Forum on Medical Humanities (EFMH), a project-based teaching practice. Based on Rogers' learner-centered humanistic teaching approach which emphasizes students' involvement and experiences in learning, EFMH puts students and their practice in a central place. After four-year exploration and operation, the Forum has developed from a small-scaled embryo into an internationalized, standardized and professionalized event, having produced fruitful outcomes. It is expected that the success of EFMH will provide inspiring experiences and enlightenments for higher medical education in terms of academic English teaching and teachers' responsibilities to foster high-quality medical students.
基金the Johan GadolinScholarship Programme at the Johan Gadolin Process Chemistry Centre at Abo Akademi University (Finland)the National Natural Science Foundation of China (No. 31470609)
文摘In this study, the characteristics of nanocellulose extracted from bleached softwood and hardwood pulps by formic acid hydrolysis followed by TEMPO-mediated oxidation were compared using transmission electron microscopy(TEM), atomic force microscopy(AFM), Fourier transform infrared analysis(FT-IR), X-ray diffraction(XRD), and thermal gravimetric analysis(TGA). The experimental results showed that the nanocellulose products derived from spruce pulp exhibited a relatively larger particle size, higher crystallinity, and higher thermal stability, compared with the corresponding products obtained from aspen pulp under the same conditions.Furthermore, the study helped establish that the properties of the nanocellulose products were highly dependent on the nature of the starting materials under identical processing conditions.
基金the special fund for Independent Innovation and Industry Development in the Core Area in Haidian District of Beijing (255-kjc020)
文摘Nanocellulose(NC) has attracted much interest in the tissue engineering(TE) field because of its properties including biocompatibility,renewability, non-toxicity, functionality, and excellent mechanical performance. This review mainly focused on the advanced applications of NC-based composites in hard TE including cartilage TE, bone TE, and dental TE, illustrated the processing methods for synthesizing scaffolds including electrospinning, freeze-drying, and 3 D printing, reviewed the current status of hard TE, and presented perspective on the future of TE technology.
基金the National Natural Science Foundation of China (51373131)Fundamental Research Funds for the Central Universities (XDJK2016A017 and XDJK2016C033 )+1 种基金Project of Basic Science and Advanced Technology Research, Chongqing Science and Technology Commission (cstc2016, jcyjA0796)the Talent Project of Southwest University (SWU115034)
文摘Cellulose nanocrystals (CNCs), a unique and promising natural material extracted from native cellulose, have attracted considerable attention owing to their physical properties and special surface chemistry. This review focuses on chemical conjugation strategies that can be used for preparation of ?uorescent-molecule labeled CNCs and the development of biomaterials. Furthermore, their application in the detection of metal ions and future development prospects are discussed. We hope to provide a clear view of the strategies for surface fluorescent modifcation of CNCs and their application in detection of metal ions.
基金Sponsored by the National Natural Science Foundation of China (Grant No. 70171039)Major Project of the National Natural Science Foundation of China (Grant No. 70131010 )Natural Science Foundation of Heilongjiang Province (Grant No. G01-09)
文摘A fuzzy integral based way of measurement assessment has been established by using linguistic varia-bles and combining fuzzy integral with hierarchy analysis for measurement of medium and small enterprises'product innovation. The conclusions drawn from analyses made with 20 medium and small enterprises providebases for governments to formulate applicable policies and for medium and small enterprises to enhance theirproduct innovation.
文摘Focusing on the reform initiatives of Chinese Academy of Medical Sciences(CAMS) & Peking Union Medical College(PUMC) in medical scientific and technological innovation from perspectives of deepening the reform and optimizing the ecosystem of science and technology innovation,this article summarizes the highlights of CAMS & PUMC’s efforts in safeguarding people’ s health and promoting the Healthy China 2030 strategy through scientific and technological innovation in the fields including basic research,disease prevention and treatment,and medical technology in the past ten years.These achievements embody the endeavors and responsibility of CAMS& PUMC in realizing self-reliance and self-improvement of Chinese medical science and technology and highlight its contributions to the development of medical science and technology of China.
文摘The project analyzes the student's participation in complementary activities such as Education Tutorial Program, Junior Company and Academic Center. These organizations have the goal to improve, expand and connect knowledge learned during classes with several practical activities. They can provide a huge integration between the students and the professors in order to achieve better results in the pedagogical, structural and organizational parts of an engineering major degree. Therefore, the project goes through the impact of each entity in the student's life and the advantages to professional future, focusing the presence of these organizations in the Electrical Engineering Course of Federal University of Rio Grande do Norte.
文摘Practice education is an important part of application-oriented higher education. Yet it poses many challenges when the design of practice education is questioned concerning whether it actually fulfills the education purpose for high quality future professionals. This paper thus introduces an innovated "base"-driven model of practice education in Zhejiang University City College in China, with a purpose to provide empirical experiences that may be valuable for the decision-making of practice education design in higher education institutions. The paper progresses by examining the philosophy of its innovated model, discussing the framework, and further highlights a strategic consideration when designing practice education activities in higher education institutions.
文摘The new media especially the use of mobile phone for information has a profound impact on contemporary university students' behavior, psychology, and way of thinking. This article will elaborate on the moral education work with university students to explore innovative ideas and innovative approaches from the perspective of interpersonal communication, political science, and sociology under the new media environment. Then the article will put forward countermeasures and improvement strategies.