RIGHT INFERIOR FRONTAL GYRUS PROCESSING OF VISUAL EROTIC INFORMATION BASED ON fMRI

Visually-induced erotic arousal evoked by pornographic visual stimuli, such as films or photographs, is a common occurrence in human behavior. The brain activation associated with visual erotic stimuli in heterosexual right handed females is studied. Functional magnetic resonance imaging is used to investigate 15 female partici- panterotic arousal induced by visual stimuli in film and picture forms, respectively, performing three or more times during their menstrual cycle on a 3.0T magnetic resonance imaging scanner. There is activation of a set of bilateral brain areas, including the inferior lateral occipital cortex, the anterior supramarginal gyrus, the parietal operculum cortex, the superior parietal lobules, the right inferior frontal gyrus, the cerebellum, the hypothalamus, the thalamus, the hippocampus, and the mid-brain. From different regions, the brain activation is observed and the inferior frontal gyrus has found to be task-independent. Furthermore, the right inferior frontal gyrus has more activation than the left inferior frontal gyrus. The result shows that the right inferior frontal gyrus plays an important role in pornographic information processing rather than being activated stimuli property specific. It is presented for the first time that the functional laterization of the inferior frontal gyrus is bi-directional rather than single （left） directional.

Regulative Effects of Auricular Acupuncture,Moxibustion and Chinese Herbs on Immunologic Function in the D-Galactose-induced Aging Mouse

Objective:To observe the regulative effect of auricular acupuncture, moxibustion and Chinese herbs on immunologic function in the D-galactose-induced aging mouse and to probe the feasibility and possible mechanisms for delaying aging, so as to provide experimental basis for acupuncture, moxibustion and Chinese herbs for delaying aging. Methods: Aging mouse model was established by subcutaneous injection of D-galactose, and treated by auricular acupuncture, auricular acupuncture plus moxibustion, and auricular acupuncture plus Chinese herbs respectively for 6 weeks and then serum interleukin-2 (IL-2) and IL-6 contents and splenic lymphocyte transformation rate were compared among the groups. Results: Compared with the young group, the serum IL-2 level and the splenic lymphocyte transformation rate significantly decreased and the IL-6 level significantly increased in the aging mouse. After treatment by auricular acupuncture, auricular acupuncture plus Chinese herbs, especially auricular acupuncture plus moxibustion, the serum IL-2 level and the splenic lymphocyte transformation rate significantly increased, and the IL-6 level significantly decreased as compared with the model group. Conclusions: Combined application of auricular acupuncture, moxibustion and Chinese herbs can improve the decline or dysfunction of immunological function in the aging organism to a certain extent.

The molecular mechanisms of Yang Wei Kang Liu powder on anticancer and reducing chemotherapy side-effect in combination with chemotherapy

Objective:We studied the molecular mechanisms of Yang Wei Kang Liu Power(YWKL,traditional Chinese medicine for nourishing stomach and anticancer) on anticancer and reducing chemotherapy side-effect in combination with chemotherapy.Methods:615 pre-cancer mouse model of YWKL for 10 days and CTX 1 time,semi-quantitative reverse transcription-polymerase chain reaction(RT-PCR) to detect bone marrow granulocyte-macrophage colony-stimulating factor(GM-CSF) gene and cancer proto-oncogene Bcl-2,c-myc expression.Results:YWKL in combination with chemotherapy could obviously promoted the expression of GM-CSF gene and inhibited the expression of Bcl-2 and c-myc oncogenes of FC 615 mice.Conclusion:The molecular mechanisms of anticancer and reducing chemotherapy side-effect of YWKL in combination with chemotherapy are to promote the expression of GM-CSF gene and inhibit the expression of Bcl-2 and c-myc oncogenes.

Chemical constituents of the twigs and leaves of Erythrina strica

A total of 15 compounds were extracted from the ethyl acetate extraction of the twigs and leaves of Erythrina strica.Based on NMR spectral data, their structures were identified as loliolide(1), phaseic acid(2), pinnatififidanoid A(3), soyasapogenol E(4), soyasapogenol B(5), 2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid(6), 3β,22β,24-trihydroxyolean-12-en-29-oic acid(oxytrogenin)(7),(23 Z)-9,19-cycloart-23-ene-3β,25-diol(8), 3,4-dihydroxybenzoic acid(9), syringaresinol(10),(E)-4-hydroxy-dodec-2-enedioic acid(11), lutein(12), ergosterol-5,8-peroxide(13), β-sitosterol(14), and daucosterol(15). Except for compounds 13–15,all the compounds were isolated from this plant for the first time. Moreover, sesquiterpenoids were isolated from Erythrina genus for the first time.

Localizing epileptic focus and assessing electrical stimulus effects on epilepsy in rats using stretchable micro electrocorticogram electrodes

Epilepsy is a chronic nervous disease with increasing incidence worldwide,while the accurate localization of epileptic focus and the corresponding treatment are still challenging due to the lack of effective tools to monitor and modulate the related brain neurological activities.In this work,stretchable micro electrocorticogram(mECoG)electrodes are developed and used to investigate penicillininduced epilepsy in rats.The electrodes possess excellent stretchability,conformality,anti-interference ability and sufficient resolution to successfully monitor electroencephalogram(EEG)signals,which is superior to traditional rigid polyimide-based electrodes.Characteristic epileptic spike waves are detected and analyzed to study the epileptic focus and electrical stimulus effects during epileptic seizures.It is found that the spike waves occur first in the visual cortex which is likely to be the epileptic focus.Epileptic spike wave frequency quickly increases to 1.07 Hz where it reaches a plateau and remains stable.There is no dominant brain hemisphere that would show early warning of epileptic seizures.Electrical stimuli for various times are applied after administering penicillin.It is found that 15 min of electrical stimulus has the best restraining effect on epileptic seizures.The mECoG electrodes developed in this study show potentials for applications in stretchable biomedical devices.

Effect of acupuncture combined with rehabilitation training on walking function after arthroscopic meniscus repair

Objective： To observe the effect of acupuncture combined with rehabilitation training on walking function after arthroscopic meniscus repair. Methods： A total of 60 cases after arthroscopic meniscus repair were randomly allocated into an observation group and a control group, 30 in each group. Cases in the observation group received acupuncture combined with standard rehabilitation training, whereas cases in the control group only received the standard rehabilitation training. The energy, support torque and swing torque of the knee joints in the two groups were measured and compared before treatment, after 1-month and 2-month treatments. Results： Before treatment, there were no between-group significant differences in the differences of energy, support torque and swing torque of the knee joints （P〉0.05）. After 1-month and 2-month treatments, there were intra-group and inter-group statistical differences in these parameters （P〈0.05）. Conclusion： Acupuncture combined with rehabilitation training can increase the energy, support torque and swing torque of the knee joints of patients after arthroscopic meniscus repair and improve their walking function.