[Objective] To study virtual plant modeling based on mutual feedback of function-structure.[Method] With the analysis of the shortcomings of current virtual plant modeling method,the modeling with the idea of function...[Objective] To study virtual plant modeling based on mutual feedback of function-structure.[Method] With the analysis of the shortcomings of current virtual plant modeling method,the modeling with the idea of function-structure mutual feedback was put forward,and the steps of this modeling were elaborated,including the determination of morphological structure model,biomass production model,biomass allocation model,organ reconstruction model,and the integration method of function model and morphological structure model.[Results] The breakthrough of function-structure mutual feedback based mechanism from the boundaries of physiological ecology model and morphological structure model can solve the difficulty of data transmission between the two models and build an integrated model from the two,which can effectively reflect the incidence relation between plant morphology and function,and more suitable for the growth mechanisms of plants.This modeling approach has significant advantages in the dynamic simulation of plant growth.[Conclusion] The virtual plant modeling based on function-structure mutual feedback provides basis for the simulation of plant growth status in the next stage,and has important significance for the accurate simulation of the dynamic growth process of plant.展开更多
The Follow up Move Research has been deepening after it was first defined in 1975 by Sinclair and Coulthard, but it has not been paid attention in China, let alone study its effect in the classroom. In this essay base...The Follow up Move Research has been deepening after it was first defined in 1975 by Sinclair and Coulthard, but it has not been paid attention in China, let alone study its effect in the classroom. In this essay based on the author's literature reading, the Follow up move functions and their language features are classified; its pragmatic motivations are researched and some factors which affect its relevance of occurrence are studied. Then with this guide of the frame four teachers classroom follow up moves are studied. Finally, the other scholars' findings in this field are commented and then the author's own insights are put forward.展开更多
[Objective] This study aimed to construct Brassica napus chloroplast multi- cistron double cross-over expression vector, to lay the foundation for the genetic engi- neering research of Brassica napus chloroplast. [Met...[Objective] This study aimed to construct Brassica napus chloroplast multi- cistron double cross-over expression vector, to lay the foundation for the genetic engi- neering research of Brassica napus chloroplast. [Method] Two primers were designed based on the known Brassica napus chloroplast DNA sequences AF267640 and Z50868 in GenBank. By using PCR method, two Brassica napus L. chloroplast DNA fragments were obtained, which were named RbcL and ACCD. The two Brassica na- pus chloroplast DNA homologous fragments were then cloned into plasmid pMD18-T to obtain recombinant plasmid pHBM715. Tandem expression cassette harboring spectinomycin-resistant gene aadA, mannanase gene man and green fluorescent pro- tein gene gfp was cloned into the plasmid pHBM715, thereby constructing Brassica napus chloroplast multicistron double cross-over expression vector pHBM716, which was transformed into Escherichia coil for expression and identification. [Result] Plate qualitative analysis was conducted for the functional identification of expression cas- sette in the constructed Brassica napus chloroplast multicistron double cross-over ex- pression vector, results showed that the three genes of the same multicistron were all expressed in E. coil [Conclusion] This study successfully constructed Brassica napus chloroplast multicistron double cross-over expression vector, which laid the foundation for the genetic engineering of Brassica napus chloroplast.展开更多
Continued advances in surgical techniques and immunosuppressive therapy have allowed liver transplantation to become an extremely successful treatment option for patients with end-stage liver disease.Beginning with th...Continued advances in surgical techniques and immunosuppressive therapy have allowed liver transplantation to become an extremely successful treatment option for patients with end-stage liver disease.Beginning with the revolutionary discovery of cyclosporine in the 1970s,immunosuppressive regimens have evolved greatly and current statistics confirm one-year graft survival rates in excess of 80%. Immunosuppressive regimens include calcineurin inhibitors,anti-metabolites,mTOR inhibitors,steroids and antibody-based therapies.These agents target different sites in the T cell activation cascade,usually by inhibiting T cell activation or via T cell depletion.They are used as induction therapy in the immediate periand post-operative period,as long-term maintenance medications to preserve graft function and as salvage therapy for acute rejection in liver transplant recipients. This review will focus on existing immunosuppressive agents for liver transplantation and consider newer medications on the horizon.展开更多
Functionalized graphene nano-sheets(FGN) of 0.01%-0.05%(mass fraction) were added to produce FGN-cement composites in the form of mortars. Flow properties, mechanical properties and microstructure of the cementitious ...Functionalized graphene nano-sheets(FGN) of 0.01%-0.05%(mass fraction) were added to produce FGN-cement composites in the form of mortars. Flow properties, mechanical properties and microstructure of the cementitious material were then investigated. The results indicate that the addition of FGN decreases the fluidity slightly and improves mechanical properties of cement-based composites significantly. The highest strength is obtained with FGN content of 0.02% where the flexural strength and compressive strength at 28 days are 12.917 MPa and 52.42 MPa, respectively. Besides, scanning electron micrographs show that FGN can regulate formation of massive compact cross-linking structures and thermo gravimetric analysis indicates that FGN can accelerate the hydration reaction to increase the function of the composite effectively.展开更多
A growing number of three-dimensional(3D)-print- ing processes have been applied to tissue engineering. This paper presents a state-of-the-art study of 3D-printing technologies for tissue-engineering applications, wit...A growing number of three-dimensional(3D)-print- ing processes have been applied to tissue engineering. This paper presents a state-of-the-art study of 3D-printing technologies for tissue-engineering applications, with particular focus on the development of a computer-aided scaffold design system; the direct 3D printing of functionally graded scaffolds; the modeling of selective laser sintering(SLS) and fused deposition modeling(FDM) processes; the indirect additive manufacturing of scaffolds, with both micro and macro features; the development of a bioreactor; and 3D/4D bioprinting. Technological limitations will be discussed so as to highlight the possibility of future improvements for new 3D-printing methodologies for tissue engineering.展开更多
Alkalinity is one of the most important parameters that influence microbial metabolism and activity during sulfate-laden wastewater biological treatment. To comprehensively understand the structure and dynamics of fun...Alkalinity is one of the most important parameters that influence microbial metabolism and activity during sulfate-laden wastewater biological treatment. To comprehensively understand the structure and dynamics of functional microbial community under alkalinity changes in sulfate-reducing continuous stirred tank reactor (CSTR), fluorescent in situ hybridization (FISH) technique was selected for qualitative and semi-quantitative analysis of functional microbial compositions in activated sludge. During 93d of bioreactor operation, the influent alkalinity was adjusted by adding sodium bicarbonate from 4000mg·L^-1 down to 3000mg·L^-1, then to 1500mg·L^-1, whereas other parameters, such as the loading rates of chenucal oxygen demand (COD) and sulfate (SO4^2-), hydraulic retention time (HRT), and pH value, were continuously maintained at 24g·L^-1·d^-1 and 4.8g·L^-1·d^-1, 10h,and about 6.7, respectively. Sludge samples were collected during diflerent alkalinity levels, and total Bacteria, tlae sulfate-reducing bacteria (SRB), and four SRB genera were demonstrated with 16S ribosomal .RNA-targeted oligonucleotide probes. The results indicated that bioreactor started-up successfully in 30d. The two instances ot drop in alkalinity resulted in the fluctuation of sulfate removal rate. The diversity of SRB community showed significant shift, and the alteration of microbial community directly resulted in the corresponding statuses of bioreactor. The dominant genera during the bioreactor start-up and alkalinity drops were Desulfovibrio, Desulfobacter, Desulfovibrio, Desulfobacter, and Desulfovibrio, respectively. In addition, the acetotrophic SRB sutterecl more trom me reduction of alkalinity than the non-acetotrophic SRB. This strategy can present the functional microbial community structure during start-up and alkalinity drop stages, and provides a powerful theoretical guideline for optimization and adjustment of bioreactor, as well.展开更多
Between the two major arsenic-containing salts in natural water, arsenite(As(Ⅲ)) is far more harmful to human and the environment than arsenate(As(V)) due to its high toxicity and transportability. Therefore, preoxid...Between the two major arsenic-containing salts in natural water, arsenite(As(Ⅲ)) is far more harmful to human and the environment than arsenate(As(V)) due to its high toxicity and transportability. Therefore, preoxidation of As(Ⅲ) to As(V) is considered to be an effective means to reduce the toxicity of arsenic and to promote the removal efficiency of arsenic. Due to their high catalytic activity and arsenic affinity, iron-based functional materials can quickly oxidize As(Ⅲ) to As(V) in heterogeneous Fenton-like systems, and then remove As(V) from water through adsorption and surface coprecipitation. In this review, the effects of different iron-based functional materials such as zero-valent iron and iron(hydroxy) oxides on arsenic removal are compared, and the catalytic oxidation mechanism of As(Ⅲ) in heterogeneous Fenton process is further clarified. Finally, the main challenges and opportunities faced by iron-based As(Ⅲ) oxidation functional materials are prospected.展开更多
A kind of predator-prey system of Holling typeⅡand interaction perturbation with impulsive effect is presented.By using Floquet theory and small amplitude perturbations skills,the locally asymptotical stability of pr...A kind of predator-prey system of Holling typeⅡand interaction perturbation with impulsive effect is presented.By using Floquet theory and small amplitude perturbations skills,the locally asymptotical stability of prey-eradication periodic solution and the permanence of the system are discussed and the corresponding threshold conditions are given respectively.Finally,the existence of positive periodic solution is investigated by the bifurcation theory.展开更多
The junction between the esophagus and the stomach is a specialized region, composed of lower esophageal sphincter (LES) and its adjacent anatomical structures, the gastric sling and crural diaphragm. Together these s...The junction between the esophagus and the stomach is a specialized region, composed of lower esophageal sphincter (LES) and its adjacent anatomical structures, the gastric sling and crural diaphragm. Together these structures work in a coordinated manner to allow ingested food into the stomach while preventing reflux of gastric contents across the esophago-gastric junction (EGJ) into the esophagus. The same zone also permits retrograde passage of air and gastric contents into esophagus during belching and vomiting. The precise coordination required to execute such a complicated task is achieved by a finely-regulated high-pressure zone. This zone keeps the junction between esophagus and stomach continuously closed, but is still able to relax briefly via input from inhibitory neurons that are responsible for its innervation. Alterations of the structure and function of the EGJ and the LES may predispose to gastroesophageal reflux disease (GERD).展开更多
As a main channel for the foreign economic cooperation of China nuclear industry,China Zhongyuan Engineering Corporation (CZEC) has been constantly engaged in technical modifications and management innovations in its ...As a main channel for the foreign economic cooperation of China nuclear industry,China Zhongyuan Engineering Corporation (CZEC) has been constantly engaged in technical modifications and management innovations in its exporting nuclear reactor projects.In the implementation of heavy water research reactor contract in Algeria,CZEC had established a complete and adequate design standards system in compliance with the international standards,and made significant modifications to the reference reactor in the aspects of reactor power and reactor safety,solved quite some technical issues which affected the reactor technical performance.The modifications and improvements enabled the technical parameters,safety features,reactor multipurpose application to attain to the advanced level in the world.In the 300 MWe PWR NPPs in Pakistan,safety features had been updated in line with upgrading regulatory requisites.The design philosophy and technology application demonstrated CZEC's creation and innovation on basis of constant safety enhancement of nuclear power projects.Efforts had also been made by CZEC in promoting China made equipment items and components exportation.展开更多
NAC family genes encode plant-specific transcription factors involved in diverse biological processes. In this study, the Arabidopsis NAC gene ATAF1 was found to be induced by drought, high-salinity, abscisic acid (...NAC family genes encode plant-specific transcription factors involved in diverse biological processes. In this study, the Arabidopsis NAC gene ATAF1 was found to be induced by drought, high-salinity, abscisic acid (ABA), methyl jasmonate, mechanical wounding, and Botrytis cinerea infection. Significant induction of ATAF1 was found in an ABA-deficient mutant aba2 subjected to drought or high salinity, revealing an ABA-independent mechanism of expression. Arabidopsis ATAFl-overexpression lines displayed many altered phenotypes, including dwarfism and short primary roots. Furthermore, in vivo experiments indicate that ATAF1 is a bonafide regulator modulating plant responses to many abiotic stresses and necrotrophic-pathogen infection. Overexpression of ATAF1 in Arabidopsis increased plant sensitivity to ABA, salt, and oxidative stresses. Especially, ATAF1 overexpression plants, but not mutant lines, showed remarkably enhanced plant tolerance to drought. Additionally, ATAF1 overexpression enhanced plant susceptibility to the necrotrophic pathogen B. cinerea, but did not alter disease symptoms caused by avirulent or virulent strains of P. syringae pv tomato DC3000. Transgenic plants overexpressing ATAF1 were hypersensitive to oxidative stress, suggesting that reactive oxygen intermediates may be related to ATAFl-mediated signaling in response to both pathogen and abiotic stresses.展开更多
This paper presents an architecture of a hybrid recommender system in E-commerce environment. The goal of the system is to make special improvements in giving precisely personalized recommendation through some effecti...This paper presents an architecture of a hybrid recommender system in E-commerce environment. The goal of the system is to make special improvements in giving precisely personalized recommendation through some effective measures. Based on the study on the existing recommendation methods of both the conventional similarity function and the conventional feedback function, several improvement algorithms are developed to enhance the precision of recommendation, which include three improved similarity functions, four improved feedback functions, and adoption of both explicit and implicit preferences in individual user profile. Among them, issues and countermeasures of a new user, prominent preferences and long-term preferences are nicely addressed to gain better recommendation. The users preferences is so designed to be precisely captured by a user-side agent, and can make self-adjustment with explicit or implicit feedback.展开更多
The present paper addresses the subject of truss damage identification using measured frequency response functions (FRF). Damage identification matrix is formed using measured FRFs obtained from truss dynamic test. Th...The present paper addresses the subject of truss damage identification using measured frequency response functions (FRF). Damage identification matrix is formed using measured FRFs obtained from truss dynamic test. Then using principal component analysis (PCA),the variable space dimensions of damage identification matrix can be reduced,and original data characters of FRFs can be analyzed and extracted from lower dimension variable space. Thus truss damages can be identified using the multivariate control chart of first several order principal components which contain almost all of original data information. Without the need for modal parameters,the method avoids the errors of modal fitting. In order to validate the reliability of the method,a whole size truss was tested with six types of damage case concerning single or two element damages. The experimental result shows that the proposed method is straightforward and reliable for truss damage identification. Especially,the method has good applicability for the truss under noisy environment and non-linear cases.展开更多
This study addresses the adaptive control and function projective synchronization problems between 2D Rulkov discrete-time system and Network discrete-time system. Based on backstepping design with three controllers, ...This study addresses the adaptive control and function projective synchronization problems between 2D Rulkov discrete-time system and Network discrete-time system. Based on backstepping design with three controllers, a systematic, concrete and automatic scheme is developed to investigate the function projective synchronization of discretetime chaotic systems. In addition, the adaptive control function is applied to achieve the state synchronization of two discrete-time systems. Numerical results demonstrate the effectiveness of the proposed control scheme.展开更多
Exosomes, secreted by many live cells, are small non-cell vesicles with nanoparticle-grade size. In addition to the original function of discarding the uselessful membrane molecules, exosomes are involved in a range o...Exosomes, secreted by many live cells, are small non-cell vesicles with nanoparticle-grade size. In addition to the original function of discarding the uselessful membrane molecules, exosomes are involved in a range of immunoregulatory functions. Dendritic cell-derived exosomes and tumor-derived exosomes are the best characterized vesicles with potent anti- tumor effect by efficiently inducing immune response. Down-regulation of immune response or induction of immune tolerance is another interesting function of exosomes. Further functional studies of the exosomes will shed light on the application of exosomes.展开更多
The alkylation of p-cresol with tert-butanol(TBA)to 2-tert-butyl-p-cresol(TBC)catalyzed by a novel multiple-SO3H functioned ionic liquid(IL1)was investigated.Meanwhile,the catalytic activity of this novel ionic ...The alkylation of p-cresol with tert-butanol(TBA)to 2-tert-butyl-p-cresol(TBC)catalyzed by a novel multiple-SO3H functioned ionic liquid(IL1)was investigated.Meanwhile,the catalytic activity of this novel ionic liquid was compared with other four traditional ionic liquids.The results showed that IL1 has superior catalytic activity to other four traditional ionic liquids with the conversion of 85.3%and selectivity of 95.2%.Also,the reaction conditions were investigated to obtain the optimum conditions.Operational simplicity,small amount of usage,high activity,reusability and selectivity are the key features of this methodology.展开更多
基金Supported by the National Natural Science Foundation of China (610620-07)the Principal Fund Project of Tarim University (TDZKSS201115)~~
文摘[Objective] To study virtual plant modeling based on mutual feedback of function-structure.[Method] With the analysis of the shortcomings of current virtual plant modeling method,the modeling with the idea of function-structure mutual feedback was put forward,and the steps of this modeling were elaborated,including the determination of morphological structure model,biomass production model,biomass allocation model,organ reconstruction model,and the integration method of function model and morphological structure model.[Results] The breakthrough of function-structure mutual feedback based mechanism from the boundaries of physiological ecology model and morphological structure model can solve the difficulty of data transmission between the two models and build an integrated model from the two,which can effectively reflect the incidence relation between plant morphology and function,and more suitable for the growth mechanisms of plants.This modeling approach has significant advantages in the dynamic simulation of plant growth.[Conclusion] The virtual plant modeling based on function-structure mutual feedback provides basis for the simulation of plant growth status in the next stage,and has important significance for the accurate simulation of the dynamic growth process of plant.
文摘The Follow up Move Research has been deepening after it was first defined in 1975 by Sinclair and Coulthard, but it has not been paid attention in China, let alone study its effect in the classroom. In this essay based on the author's literature reading, the Follow up move functions and their language features are classified; its pragmatic motivations are researched and some factors which affect its relevance of occurrence are studied. Then with this guide of the frame four teachers classroom follow up moves are studied. Finally, the other scholars' findings in this field are commented and then the author's own insights are put forward.
基金Supported by National 863 Project of China (2002AA227011)Natural Science Foundation of Hubei Province (2003ABAI18)Natural Science Foundation of Shandong Province (ZR2010HQ054)~~
文摘[Objective] This study aimed to construct Brassica napus chloroplast multi- cistron double cross-over expression vector, to lay the foundation for the genetic engi- neering research of Brassica napus chloroplast. [Method] Two primers were designed based on the known Brassica napus chloroplast DNA sequences AF267640 and Z50868 in GenBank. By using PCR method, two Brassica napus L. chloroplast DNA fragments were obtained, which were named RbcL and ACCD. The two Brassica na- pus chloroplast DNA homologous fragments were then cloned into plasmid pMD18-T to obtain recombinant plasmid pHBM715. Tandem expression cassette harboring spectinomycin-resistant gene aadA, mannanase gene man and green fluorescent pro- tein gene gfp was cloned into the plasmid pHBM715, thereby constructing Brassica napus chloroplast multicistron double cross-over expression vector pHBM716, which was transformed into Escherichia coil for expression and identification. [Result] Plate qualitative analysis was conducted for the functional identification of expression cas- sette in the constructed Brassica napus chloroplast multicistron double cross-over ex- pression vector, results showed that the three genes of the same multicistron were all expressed in E. coil [Conclusion] This study successfully constructed Brassica napus chloroplast multicistron double cross-over expression vector, which laid the foundation for the genetic engineering of Brassica napus chloroplast.
文摘Continued advances in surgical techniques and immunosuppressive therapy have allowed liver transplantation to become an extremely successful treatment option for patients with end-stage liver disease.Beginning with the revolutionary discovery of cyclosporine in the 1970s,immunosuppressive regimens have evolved greatly and current statistics confirm one-year graft survival rates in excess of 80%. Immunosuppressive regimens include calcineurin inhibitors,anti-metabolites,mTOR inhibitors,steroids and antibody-based therapies.These agents target different sites in the T cell activation cascade,usually by inhibiting T cell activation or via T cell depletion.They are used as induction therapy in the immediate periand post-operative period,as long-term maintenance medications to preserve graft function and as salvage therapy for acute rejection in liver transplant recipients. This review will focus on existing immunosuppressive agents for liver transplantation and consider newer medications on the horizon.
基金Project(51102035)supported by the National Natural Science Foundation of China
文摘Functionalized graphene nano-sheets(FGN) of 0.01%-0.05%(mass fraction) were added to produce FGN-cement composites in the form of mortars. Flow properties, mechanical properties and microstructure of the cementitious material were then investigated. The results indicate that the addition of FGN decreases the fluidity slightly and improves mechanical properties of cement-based composites significantly. The highest strength is obtained with FGN content of 0.02% where the flexural strength and compressive strength at 28 days are 12.917 MPa and 52.42 MPa, respectively. Besides, scanning electron micrographs show that FGN can regulate formation of massive compact cross-linking structures and thermo gravimetric analysis indicates that FGN can accelerate the hydration reaction to increase the function of the composite effectively.
基金Singapore National Research Foundation (NRF) for funding the Singapore Centre for 3D Printing (SC3DP)
文摘A growing number of three-dimensional(3D)-print- ing processes have been applied to tissue engineering. This paper presents a state-of-the-art study of 3D-printing technologies for tissue-engineering applications, with particular focus on the development of a computer-aided scaffold design system; the direct 3D printing of functionally graded scaffolds; the modeling of selective laser sintering(SLS) and fused deposition modeling(FDM) processes; the indirect additive manufacturing of scaffolds, with both micro and macro features; the development of a bioreactor; and 3D/4D bioprinting. Technological limitations will be discussed so as to highlight the possibility of future improvements for new 3D-printing methodologies for tissue engineering.
基金Supported by the National Natural Science Foundation of China (No.50208006).
文摘Alkalinity is one of the most important parameters that influence microbial metabolism and activity during sulfate-laden wastewater biological treatment. To comprehensively understand the structure and dynamics of functional microbial community under alkalinity changes in sulfate-reducing continuous stirred tank reactor (CSTR), fluorescent in situ hybridization (FISH) technique was selected for qualitative and semi-quantitative analysis of functional microbial compositions in activated sludge. During 93d of bioreactor operation, the influent alkalinity was adjusted by adding sodium bicarbonate from 4000mg·L^-1 down to 3000mg·L^-1, then to 1500mg·L^-1, whereas other parameters, such as the loading rates of chenucal oxygen demand (COD) and sulfate (SO4^2-), hydraulic retention time (HRT), and pH value, were continuously maintained at 24g·L^-1·d^-1 and 4.8g·L^-1·d^-1, 10h,and about 6.7, respectively. Sludge samples were collected during diflerent alkalinity levels, and total Bacteria, tlae sulfate-reducing bacteria (SRB), and four SRB genera were demonstrated with 16S ribosomal .RNA-targeted oligonucleotide probes. The results indicated that bioreactor started-up successfully in 30d. The two instances ot drop in alkalinity resulted in the fluctuation of sulfate removal rate. The diversity of SRB community showed significant shift, and the alteration of microbial community directly resulted in the corresponding statuses of bioreactor. The dominant genera during the bioreactor start-up and alkalinity drops were Desulfovibrio, Desulfobacter, Desulfovibrio, Desulfobacter, and Desulfovibrio, respectively. In addition, the acetotrophic SRB sutterecl more trom me reduction of alkalinity than the non-acetotrophic SRB. This strategy can present the functional microbial community structure during start-up and alkalinity drop stages, and provides a powerful theoretical guideline for optimization and adjustment of bioreactor, as well.
基金financially supported by the National Science Fund for Excellent Young Scholars of China (No. 52022111)the Distinguished Young Scholars of China (No. 51825403)the National Natural Science Foundation of China (Nos. 51634010, 51974379)。
文摘Between the two major arsenic-containing salts in natural water, arsenite(As(Ⅲ)) is far more harmful to human and the environment than arsenate(As(V)) due to its high toxicity and transportability. Therefore, preoxidation of As(Ⅲ) to As(V) is considered to be an effective means to reduce the toxicity of arsenic and to promote the removal efficiency of arsenic. Due to their high catalytic activity and arsenic affinity, iron-based functional materials can quickly oxidize As(Ⅲ) to As(V) in heterogeneous Fenton-like systems, and then remove As(V) from water through adsorption and surface coprecipitation. In this review, the effects of different iron-based functional materials such as zero-valent iron and iron(hydroxy) oxides on arsenic removal are compared, and the catalytic oxidation mechanism of As(Ⅲ) in heterogeneous Fenton process is further clarified. Finally, the main challenges and opportunities faced by iron-based As(Ⅲ) oxidation functional materials are prospected.
基金Foundation item: Supported by the National Natural Science Foundation of China(10771179) Supported by the Natural Science Foundation of the Education Department Henan Province(2007110028)
文摘A kind of predator-prey system of Holling typeⅡand interaction perturbation with impulsive effect is presented.By using Floquet theory and small amplitude perturbations skills,the locally asymptotical stability of prey-eradication periodic solution and the permanence of the system are discussed and the corresponding threshold conditions are given respectively.Finally,the existence of positive periodic solution is investigated by the bifurcation theory.
文摘The junction between the esophagus and the stomach is a specialized region, composed of lower esophageal sphincter (LES) and its adjacent anatomical structures, the gastric sling and crural diaphragm. Together these structures work in a coordinated manner to allow ingested food into the stomach while preventing reflux of gastric contents across the esophago-gastric junction (EGJ) into the esophagus. The same zone also permits retrograde passage of air and gastric contents into esophagus during belching and vomiting. The precise coordination required to execute such a complicated task is achieved by a finely-regulated high-pressure zone. This zone keeps the junction between esophagus and stomach continuously closed, but is still able to relax briefly via input from inhibitory neurons that are responsible for its innervation. Alterations of the structure and function of the EGJ and the LES may predispose to gastroesophageal reflux disease (GERD).
文摘As a main channel for the foreign economic cooperation of China nuclear industry,China Zhongyuan Engineering Corporation (CZEC) has been constantly engaged in technical modifications and management innovations in its exporting nuclear reactor projects.In the implementation of heavy water research reactor contract in Algeria,CZEC had established a complete and adequate design standards system in compliance with the international standards,and made significant modifications to the reference reactor in the aspects of reactor power and reactor safety,solved quite some technical issues which affected the reactor technical performance.The modifications and improvements enabled the technical parameters,safety features,reactor multipurpose application to attain to the advanced level in the world.In the 300 MWe PWR NPPs in Pakistan,safety features had been updated in line with upgrading regulatory requisites.The design philosophy and technology application demonstrated CZEC's creation and innovation on basis of constant safety enhancement of nuclear power projects.Efforts had also been made by CZEC in promoting China made equipment items and components exportation.
基金We would like to thank Dr Nam-Hai Chua (Rockefeller Univer- sity) for kindly providing the pBA002Myc vector and the Arabi- dopsis Biological Resource Center (ABRC), Ohio State University for providing ToDNA insertion lines. This work was supported by grants from National Natural Science Foundation of China (No. 30530400/90717006/30670195) to Q Xie and Y Wu, the Chinese Academy of Science (KSCX2-YW-N-010 and CXTD-S2005-2), and the (iuangdong Natural Science Foundation, China (No. 5300648) to Z Deng.
文摘NAC family genes encode plant-specific transcription factors involved in diverse biological processes. In this study, the Arabidopsis NAC gene ATAF1 was found to be induced by drought, high-salinity, abscisic acid (ABA), methyl jasmonate, mechanical wounding, and Botrytis cinerea infection. Significant induction of ATAF1 was found in an ABA-deficient mutant aba2 subjected to drought or high salinity, revealing an ABA-independent mechanism of expression. Arabidopsis ATAFl-overexpression lines displayed many altered phenotypes, including dwarfism and short primary roots. Furthermore, in vivo experiments indicate that ATAF1 is a bonafide regulator modulating plant responses to many abiotic stresses and necrotrophic-pathogen infection. Overexpression of ATAF1 in Arabidopsis increased plant sensitivity to ABA, salt, and oxidative stresses. Especially, ATAF1 overexpression plants, but not mutant lines, showed remarkably enhanced plant tolerance to drought. Additionally, ATAF1 overexpression enhanced plant susceptibility to the necrotrophic pathogen B. cinerea, but did not alter disease symptoms caused by avirulent or virulent strains of P. syringae pv tomato DC3000. Transgenic plants overexpressing ATAF1 were hypersensitive to oxidative stress, suggesting that reactive oxygen intermediates may be related to ATAFl-mediated signaling in response to both pathogen and abiotic stresses.
文摘This paper presents an architecture of a hybrid recommender system in E-commerce environment. The goal of the system is to make special improvements in giving precisely personalized recommendation through some effective measures. Based on the study on the existing recommendation methods of both the conventional similarity function and the conventional feedback function, several improvement algorithms are developed to enhance the precision of recommendation, which include three improved similarity functions, four improved feedback functions, and adoption of both explicit and implicit preferences in individual user profile. Among them, issues and countermeasures of a new user, prominent preferences and long-term preferences are nicely addressed to gain better recommendation. The users preferences is so designed to be precisely captured by a user-side agent, and can make self-adjustment with explicit or implicit feedback.
基金the Foundation of Henan Province Key Technology R and D Program(Grant No.0423033700).
文摘The present paper addresses the subject of truss damage identification using measured frequency response functions (FRF). Damage identification matrix is formed using measured FRFs obtained from truss dynamic test. Then using principal component analysis (PCA),the variable space dimensions of damage identification matrix can be reduced,and original data characters of FRFs can be analyzed and extracted from lower dimension variable space. Thus truss damages can be identified using the multivariate control chart of first several order principal components which contain almost all of original data information. Without the need for modal parameters,the method avoids the errors of modal fitting. In order to validate the reliability of the method,a whole size truss was tested with six types of damage case concerning single or two element damages. The experimental result shows that the proposed method is straightforward and reliable for truss damage identification. Especially,the method has good applicability for the truss under noisy environment and non-linear cases.
基金supported by the Natural Science Foundation of China under Grant Nos.10747141 and 10735030Zhejiang Provincial Natural Science Foundation under Grant No.605408+3 种基金Ningbo Natural Science Foundation under Grant Nos.2007A610049 and 2008A61001National Basic Research Program of China (973 Program 2007CB814800)Programme for Changjiang Scholars and Innovative Research Team in University (IRT0734)K.C.Wong Magna Fund in Ningbo University
文摘This study addresses the adaptive control and function projective synchronization problems between 2D Rulkov discrete-time system and Network discrete-time system. Based on backstepping design with three controllers, a systematic, concrete and automatic scheme is developed to investigate the function projective synchronization of discretetime chaotic systems. In addition, the adaptive control function is applied to achieve the state synchronization of two discrete-time systems. Numerical results demonstrate the effectiveness of the proposed control scheme.
文摘Exosomes, secreted by many live cells, are small non-cell vesicles with nanoparticle-grade size. In addition to the original function of discarding the uselessful membrane molecules, exosomes are involved in a range of immunoregulatory functions. Dendritic cell-derived exosomes and tumor-derived exosomes are the best characterized vesicles with potent anti- tumor effect by efficiently inducing immune response. Down-regulation of immune response or induction of immune tolerance is another interesting function of exosomes. Further functional studies of the exosomes will shed light on the application of exosomes.
基金Supported by the National High Technology Research and Development Program of China(2006BAE03B06)Shanghai Leading Academic Discipline Project(B409)Shanghai International Cooperation of Science and Technology Project(06SR07101)
文摘The alkylation of p-cresol with tert-butanol(TBA)to 2-tert-butyl-p-cresol(TBC)catalyzed by a novel multiple-SO3H functioned ionic liquid(IL1)was investigated.Meanwhile,the catalytic activity of this novel ionic liquid was compared with other four traditional ionic liquids.The results showed that IL1 has superior catalytic activity to other four traditional ionic liquids with the conversion of 85.3%and selectivity of 95.2%.Also,the reaction conditions were investigated to obtain the optimum conditions.Operational simplicity,small amount of usage,high activity,reusability and selectivity are the key features of this methodology.