略论《北山移文》中的“周子”及其创作方法

孔稚圭《北山移文》中的“周子”其实就是周颙。佛道之争的矛盾冲突使孔稚圭有了写作此文的动机,但是其道学的家学渊源使得这位身浴老庄玄风的仕途中人在写作倾向上有了极为独特的风格,这就是道家普遍的“遗貌取神”的文学创作精神。

EFFECT OF ACUPUNCTURE ON NEURONAL APOPTOSIS AFTER FOCAL CEREBRAL ISCHEMIC REPERFUSION INJURY IN RATS

Objective To observe the impacts of acupuncture on cell-cycl ODK4） and neuronal death in hippocampal neurons in rats with focal cerebra e-related factors （cyclin D1, schemic reperfusion injury Methods Middle cerebral artery occlusion （MCAO） was used to establish the model of cerebral ischemic reperfusion injury. Western blot （WB） and flow cytometry （FCM） were applied to the tests of cell-cycle-related factors and apoptosis respectively. Results In 48 h of reperfusion, the expressions of cell-cycle-related factors （cyclin D1, CDK4） in hippocampal neurons and apoptosis were increased. In acupuncture group, the expressions of cyclin DI and CDK4 and apoptosis were reduced remarkably （P 〈 0.01 ）. Conclusion Acupuncture plays the protective role in cerebral ischemic reperfusion injury, which is contributed probably to the modulation of cell-cycle-related factors to inhibit apoptosis.

Expressions of MMP-2,-9,TIMP-1,-2,-3 mRNA in Rat Uterus during Estrous Cycle

Zymography and in situ hybridization were used to investigate matrixmetalloproteinase -2, -9 (MMP -2, MMP-9) activities and expressions of MMP -2, -9 and TIMP1, -2, -3 (tissue inhibitors of matrix metallo-proteinases) mRNA in the rat uterus during estrouscycle. The relative activity was semiquanted by using densitometric analysis. The MMP-2(67 kDa) activity in every stage during estrpus cycle was detected by zymography. MMP-2activity was highest at proestrus; higher at estrus and metaestrus; lowest at diestrus. Throughin situ hybridization, MMP -2, -9, TIMP -1~ -3 mRNA mainly in hasal stroma cells of uterineendometrium were detected. The positive signals of MMP -2 and -9 mRNAs in hasal stromacells were shown stronger at proestrus, estrus and metaestrus while they showed the weakest atdiestrus. The expression of MMP -2 mRNA coincided with MMP -2 activity change. MMP-2and -9 mRNAs were also highly expressed in uterine circular muscle at estrus. Weak signals ofMMP -9 mRNA were detected in uterine luminal and glandular epithelial cells at estrus.TIMP -1 mRNA in hasal stroma cells was shown as the strongest expression at estrus andmetaestrus; stronger at proestrus and the weakest at diestrus. TIMP-2 mRNA in basal stromacells was stronger at estrus and diestrus; weaker at proestrus and metaestrus. TIMP -1 and -2mRNAs were also highly expressed in uterine luminal and glandular epithelial cells at estrus.TIMP -3 mRNA in hasal stroma cells revealed the strongest expression at estrus; stronger atdiestrus and metaestrus and showed the weakest at proestrus. The mRNA was also highlyexpressed in uterine circular muscle at estrus. In short, our present results provide evidencethat MMP -2, -9 and TIMP -1~ -3 were involved in rat uterine endometrium reconstructionduring estrous cycle.

Existence of Periodic Solutions of Nonlinear Neutral Differential Equation with Deviating Argument

Existence criteria is established for the periodic solution of the nonlinear neutral delay differential equation x′(t)=f(t,x(t),x(t-τ 1(t)),x′(t-τ 2(t)))+p(t) by means of an abstract continuous theorem of k-set contractive operator and some analysis technique.

Modulation of Lianbizi Injection (Andrographolide ) on Some Immune Functions

Objective: To study the effects of andrographolide on immune functions and the immune mechanism in clinical therapy.Methods: The amounts of IFN-α,IFN-γ, TNF-α, IL-8 in the peripheral blood mononuclear cells (PBMC) culture supernatants dealt with by different concentrations of LianBiZhi (LBZ) injection, the effective component of which is andrographolide, were detected by biological activity test or ELISA in vitro. The effects of LBZ injection on macrophage phagocytotic function and natural killer cells cytotoxicity were examined by means of macrophage to phagocytize cock erythrocyte and measurement of lactate dehydrogenase (LDH) activity released from the damaged cells, respectively.Results: The LBZ injection could not only enhance the phagocytosis activity of peritoneal macrophage from guinea pig to phagocytosis cock erythrocytes, but also augment the cytotoxicity mediated by natural killer cells from PBMCs.Conclusion: Andrographolide is an immunostimulant agent which can modulate both antigen specific and nonspecific immune function by means of its natural killer cells, macrophage and cytokines.

Rational and Periodic Wave Solutions of Two-Dimensional Boussinesq Equation

Two new exact, rational and periodic wave solutions are derived for the two-dimensional Boussinesq equation. For the first solution it is obtained by performing an appropriate limiting procedure on the soliton solutions obtained by Hirota bilinear method. The second one in terms of Riemann theta function is explicitly presented by virtue of Hirota bilinear method and its asymptotic property is also analyzed in detail. Moreover, it is of interest to note that classical soliton solutions can be reduced from the periodic wave solutions.

UNDERSTANDING HREM IMAGES OF Al-Mn-Si ICOSAHEDRAL QUASICRYSTAL

提出了处理数字化图像的光滑算子。用它处理了Ａｌ－Ｍｎ－Ｓｉ二十面体准晶的高分辨电子显微图，处理后的图像展示了周期结构特征，由此建立了一个平面周期模型，其Ｆｏｕｒｉｅｒ变换图符合Ａｌ－Ｍｎ－Ｓｉ准晶相应的电子衍射图。

Akt1/p27^(kip1) Pathway Mediates Inhibition of LXA_4 on TNF-α-induced Proliferation of Rat Mesangial Cells

Objective:To examine whether lipoxin A 4(LXA 4) has an inhibitory effect on tumor necrosis factor-α(TNF-α)-induced proliferation of glomerular mesangial cells of rat, and explore the molecular mechanisms of signal pathway in LXA 4 actions. Methods: Glomerular mesangial cells of rat were cultured and treated with TNF-α(10 ng/ml), with or without preincubation with LXA 4 at different concentrations. Cell proliferation was evaluated by monotetrazolium (MTT) colorimetric assay. The expression of cyclin E mRNA was measured by RT-PCR. Phosphorylated Akt1(Thr308) and p27 kip1 were analyzed by Western blotting. Results: TNF-α-stimulated proliferation of mesangial cells was inhibited by LXA 4 in a dose-dependent manner. The marked increments in cyclin E mRNA expression induced by TNF-α during proliferation of mesangial cells were down-regulated by LXA 4. Threonine phosphorylated Akt1 proteins at 308 site stimulated by TNF-α was reduced by LXA 4. TNF-α-induced decrements in expression of p27 kip1 proteins was ameliorated by LXA 4 in a dose-dependent manner. Conclusion: TNF-α-induced proliferation of rat mesangial cells can be inhibited by TXA 4 through the mechanism of Akt 1/p27 kip1 pathway-dependent signal transduction.

Corrosion resistances of metallic materials in environments containing chloride ions:A review

Corrosion,more specifically,pitting corrosion happening extremely in marine environments,leads to lifespan of materials drastically decreasing in service,which causes enormous economic loss and even environmental disaster and casualties.In the past decade,increasing efforts have been made to study the corrosion behaviors of materials in chloride-containing aqueous environments.Herein,this work provides an overview of recent progress in understanding the degradation mechanism and improving the corrosion resistance and corrosion-wear resistance of materials from bulk metal to surface treatment involving organic coating,metal and its alloy or compound coating.The particular emphasis is given to the periodic layered structures(PLSs),whose anti-corrosion properties outperformed others to some extent,wherever in terms of bulk metal or surface treatment,regardless of aggressive environment(corrosion or corrosion-wear conditions).Numerical simulation based on kinds of models at different scales is introduced to deeply understand the process of corrosion and/or corrosion-wear in chloride-containing aqueous environment.Combined experimental result with numerical simulation,the micro-galvanic corrosion dominated degradation mechanism of PLSs is critically analyzed.Types of setups to realize corrosion-wear in laboratory are also summarized.At last,future research and development are prospected,offering to develop a basic application of PLSs designed by corrosion protection methodology in the near future.

New Families of Soliton and Periodic Solutions of Bose-Einstein Condensation in Linear Magnetic Field and Time-Dependent Laser Field

By using a new generally projective Riccati equation method and with the help of symbolic computation,we consider a nonlinear Gross-Pitaevskii equation with weak bias magnetic and time-dependent laser fields. As a result,some new soliton solutions, rational function solution, and periodic solutions are obtained.

Decoupling Bang-Bang Group for Adiabatic Decoherence Control in a Three-Level Atom

In this paper, we study the control problem of adiabatic decoherence in a three-level atom. We will find the decoupling bang-bang group for various configurations, including the V configuration and the cascade type of three-levelatom subjected to adiabatic decoherence. We also give the programs to design a sequence of periodic twinborn pulses to suppress the decoherence.

An Improved F-Expansion Method and Its Application to Coupled Drinfel'd-SokolovWilson Equation

With the aid of computerized symbolic computation, an improved F-expansion method is presented to uniformly construct more new exact doubly periodic solutions in terms of rational formal Jscobi elliptic function of nonlinear partial differential equations （NPDFs）. The coupled Drinfel＇d-Sokolov-Wilson equation is chosen to illustrate the method. As a result, we can successfully obtain abundant new doubly periodic solutions without calculating various Jacobi elliptic functions. In the limit cases, the rational solitary wave solutions and trigonometric function solutions are obtained as well.

Systematic Study on Alpha Decay Half-Lives of Superheavy Nuclei

The α-decay half-lives of a set of superheavy nuclear isotope chain from Z = 105 to 120 have been analyzed systematically within the WKB method, and some nuclear structure features are found. The decay barriers have been determined in the quasi-molecular shape path within the Generalized Liquid Drop Model （GLDM） including the proximity effects between nucleons in a neck and the mass and charge asymmetry. The results are in reasonable agreement with the published experimental data for the alpha decay half-llves of isotopes of charge 112, 114, and 116, of the element 294118 and of some decay products. A comparison of present calculations with the results by the DDM3Y effective interaction and by the Viola-Seaborg-Sobiczewski （VSS） formulae is also made. The experimental a decay half lives all stand in between the GLDM calculations and VSS formula results. This demonstrates the possibility of these models to provide reasonable estimates for the half-lives of nuclear decays by a emissions for the domain of SHN. The half-lives of these new nuclei are thus well tested from the reasonable consistence of the macroscopic, the microscopic, the empirical formulae and the experimental data. This also shows that the present data of SHN themselves are consistent. It could suggest that the present experimental claims on the existence of new elements Z =110 - 118 are reliable. It is expected that greater deviations of a few SHN between the data and the model may be eliminated by further improvements on the precision of the measurements.

Exact Discrete Soliton Solutions and Periodic Solutions to (2+1)-Dimensional Toda Lattice with a New Algebraic Method

In this paper,with the aid of symbolic computation,we present a uniform method for constructing soliton solutions and periodic solutions to (2+1)-dimensional Toda lattice equation.

An R2R3-type transcription factor gene AtMYB59 regulates root growth and cell cycle progression in Arabidopsis

MYB proteins play important roles in eukaryotic organisms. In plants, the R1R2R3-type MYB proteins function in cell cycle control. However, whether the R2R3-type MYB protein is also involved in the cell division process remains unknown. Here, we report that an R2R3-type transcription factor gene, AtMYB59, is involved in the regulation of cell cycle progression and root growth. The AtMYB59 protein is localized in the nuclei of onion epidermal cells and has transactivation activity. Expression of AtMYB59 in yeast cells suppresses cell proliferation, and the transfor- mants have more nuclei and higher anenpioid DNA content with longer cells. Mutation in the conserved domain of AtMYB59 abolishes its effects on yeast cell growth. In synchronized Arabidopsis cell suspensions, the AtMYB59 gene is specifically expressed in the S phase during cell cycle progression. Expression and promoter-GUS analysis reveals that the AtMYB59 gene is abundantly expressed in roots. Transgenic plants overexpressing AtMYB59 have shorter roots compared with wild-type plants （Arabidopsis accession Col-0）, and around half of the mitotic cells in root tips are at metaphase. Conversely, the null mutant myb59-1 has longer roots and fewer mitotic cells at metaphase than Col, suggesting that AtMYB59 may inhibit root growth by extending the metaphase of mitotic cells. AtMYB59 regulates many downstream genes, including the CYCB1;1 gene, probably through binding to MYB-responsive elements. These results support a role forAtMYB59 in cell cycle regulation and plant root growth.

Multiple Periodic-Soliton Solutions for(3+1)-Dimensional Jimbo-Miwa Equation

2N line-soliton solutions of the (3+1)-dimensional Jimbo-Miwa equation can be presented by resorting tothe Hirota bilinear method.In this paper,N periodic-soliton solutions of the (3+1)-dimensional Jimbo-Miwa equationare obtained from the 2N line-soliton solutions by selecting the parameters into conjugated complex parameters in pairs.

Expression patterns of cytokine,growth factor and cell cycle-related genes after partial hepatectomy in rats with thioacetamide-induced cirrhosis

AIM： To examine the differences in the responses of normal and cirrhotic livers to partial hepatectomy in relation to the factors influencing liver regeneration.METHODS： Cirrhosis was induced in rats by administration of thioacetarnide. Untreated rats were used as controls. The control rats as well as the cirrhotic rats were subjected to 70% partial hepatectorny. At different time points after hepatectorny, the livers were collected and the levels of cytokines, growth factors and cell cycle proteins were analyzed.RESULTS： After hepatectomy, the cirrhotic remnant expressed significantly lower levels of cyclin D1, its kinase partner, cdk4, and cyclin E as compared to the controls up to 72 h post hepatectomy. Significantly lower levels of cyclin A and cdk2 were also observed while the cdk inhibitor, p27 was significantly higher. In addition, the cirrhotic group had lower IL-6 levels than the control group at all time points up to 72 h following resection.CONCLUSION： The data from our study shows that impaired liver regeneration in cirrhotic remnants is associated with low expression of cyclins and cdks. This might be the consequence of the low IL-6 levels in cirrhotic liver remnant which would in turn influence the actions of transcription factors that regulate genes involved in cell proliferation and metabolic homeostasis during the regeneration process.

New Multiple Soliton-like and Periodic Solutions for （2＋l）-Dimensional Canonical Generalized KP Equation with Variable Coefficients

In this paper, the generalized ranch function method is extended to （2＋1）-dimensianal canonical generalized KP （CGKP） equation with variable coetfficients. Taking advantage of the Riccati equation, many explicit exact solutions, which contain multiple soliton-like and periodic solutions, are obtained for the （2＋1）-dimensional OGKP equation with variable coetffcients.

Coherently Controlled Periodic Entanglement of Two Moving Atoms in a Cavity

We analyze the entanglement of two atoms in a cavity. The evolvement of entanglement of two atoms is disorderly when two atoms in the cavity are fixed at initial time. However, the evolvement of entanglement of two atoms becomes well-regulated orderly under the coherent cavity field when atoms are in motion at beginning. We find that it is possible to control this periodic entanglement by properly choosing the velocity of atoms, and the initial state of the field.

Cell Cycle Kinetic Analysis in the Cortical Regions of the Lentil Primary Root During Germination

Cell cycle kinetic activity in the cortical cells of the lentil (Lens culinaris Me-die. cv. Verte du Puy) primary root during germination was examined both temporally and spatially. Immunohistochemical and cytological evidence indicated that DNA replication and cell division started in the cortical cells of tire lentil primary root after around 13 and 17 h of imbibition, respectively. The first cells in DNA synthesis and the First mitotic figures all appeared in the cortical cells about I mm front the root-cap junction, but these divided cells had synthesized their DNA during the maturity of seed instead of during germination. The kinetic pattern of activity of the first cell cycle showed that these cells were not activated synchronously, but re-entered the cell cycle in turn depending on their places in the root tip, However, the adjacent cells partially synchronously proceeded their cell cycle.