Basic structure and algorithm of leaf mechanism photosynthesis model were described in first part of this study based on former researcher results. Then, considering some environmental factors influencing on leaf ph...Basic structure and algorithm of leaf mechanism photosynthesis model were described in first part of this study based on former researcher results. Then, considering some environmental factors influencing on leaf photosynthesis, three numerical sensitivity experiments were carried out. We simulated the sing le leaf net CO2 assimilation, which acts as a function of different light, carbo n dioxide and temperature conditions. The relationships between leaf net photosy nthetic rate of C3 and C4 plant with CO2 concentration intercellular, leaf tempe rature, and photosynthetic active radiation (PAR) were presented, respectively. The results show the numerical experiment may indicate the main characteristic o f plant photosynthesis in C3 and C4 plant, and further can be used to integrate with the regional climate model and act as land surface process scheme, and bett er understand the interaction between vegetation and atmosphere.展开更多
Basic structure and algorithm of leaf mechanism photosynthesis model were described in first part of this study based on former researcher results. Then, considering some environmental factors influencing on leaf ph...Basic structure and algorithm of leaf mechanism photosynthesis model were described in first part of this study based on former researcher results. Then, considering some environmental factors influencing on leaf photosynthesis, three numerical sensitivity experiments were carried out. We simulated the sing le leaf net CO2 assimilation, which acts as a function of different light, carbo n dioxide and temperature conditions. The relationships between leaf net photosy nthetic rate of C3 and C4 plant with CO2 concentration intercellular, leaf tempe rature, and photosynthetic active radiation (PAR) were presented, respectively. The results show the numerical experiment may indicate the main characteristic o f plant photosynthesis in C3 and C4 plant, and further can be used to integrate with the regional climate model and act as land surface process scheme, and bett er understand the interaction between vegetation and atmosphere.展开更多
The existing collaborative recommendation algorithms have lower robustness against shilling attacks.With this problem in mind,in this paper we propose a robust collaborative recommendation algorithm based on k-distanc...The existing collaborative recommendation algorithms have lower robustness against shilling attacks.With this problem in mind,in this paper we propose a robust collaborative recommendation algorithm based on k-distance and Tukey M-estimator.Firstly,we propose a k-distancebased method to compute user suspicion degree(USD).The reliable neighbor model can be constructed through incorporating the user suspicion degree into user neighbor model.The influence of attack profiles on the recommendation results is reduced through adjusting similarities among users.Then,Tukey M-estimator is introduced to construct robust matrix factorization model,which can realize the robust estimation of user feature matrix and item feature matrix and reduce the influence of attack profiles on item feature matrix.Finally,a robust collaborative recommendation algorithm is devised by combining the reliable neighbor model and robust matrix factorization model.Experimental results show that the proposed algorithm outperforms the existing methods in terms of both recommendation accuracy and robustness.展开更多
Based on spontaneous desorption characteristic, the correlation of desorption time and gas content was analyzed and the application of it in production was researched. The desorption of high rank coalbed methane in Qi...Based on spontaneous desorption characteristic, the correlation of desorption time and gas content was analyzed and the application of it in production was researched. The desorption of high rank coalbed methane in Qinshui basin was periodic, and isotope fractionation effect also exists in the process. △δ^13C1 can be used to distinguish the stabilization of coalbed methane wells, associated with desorption rate, the individual well recoverable reserves can be calculated. Economically recoverable time can be predicted according to the logarithmic relationship between desorption gas content per ton and desorption time. The error between predicted result and numerical simulation result is only 1.5%.展开更多
Zhao (2003a) first established a congruence for any odd prime p〉3, S(1,1,1 ;p)=-2Bp-3 (mod p), which holds when p=3 evidently. In this paper, we consider finite triple harmonic sum S(α,β, γ,ρ) (modp) is...Zhao (2003a) first established a congruence for any odd prime p〉3, S(1,1,1 ;p)=-2Bp-3 (mod p), which holds when p=3 evidently. In this paper, we consider finite triple harmonic sum S(α,β, γ,ρ) (modp) is considered for all positive integers α,β, γ. We refer to w=α+β+ γ as the weight of the sum, and show that if w is even, S(α,β, γ,ρ)=0 (mod p) for p≥w+3; if w is odd, S(α,β, γ,ρ)=-rBp-w (mod p) for p≥w, here r is an explicit rational number independent ofp. A congruence of Catalan number is obtained as a special case.展开更多
Mafic intrusions and dykes are well preserved in the Yinmin and Lanniping districts, located within the western margin of the Yangtze Block, SW China. Although these mafic rocks from the two areas formed during differ...Mafic intrusions and dykes are well preserved in the Yinmin and Lanniping districts, located within the western margin of the Yangtze Block, SW China. Although these mafic rocks from the two areas formed during different periods, they share similar ranges of PGE concentration. Most of the Yinmin gabbroic dykes contain relatively high PGE concentrations (PGEs=13.9-87.0 ppb) and low S contents (0.003 %-0.020 %), higher than the maximum PGE concentrations of mafic magmas melting from the mantle. Two exceptional Yinmin samples are characterized by relatively low PGE (PGEs = 0.31-0.37 ppb)and high S (0.114 %-0.257 %) contents. In contrast, most samples from the Lanniping gabbroic intrusion have low PGE con- centrations (PGEs = 0.12-1.02 ppb) and high S contents (0.130 %-0.360 %), except that the three samples exhibit relatively high PGE (PGEs=16.3-34.8 ppb) and low S concentrations (0.014 %-0.070 %). All the Yinmin and Lanniping samples are characterized by the enrichment of PPGE relative to IPGE in the primitive-mantle normalized diagrams, and the high-PGE samples exhibit obvious Ru anomalies. This study suggests that during the ascent of the parental magma, removal of Os-Ir-Ru alloys and/or chro- mite/spinel leads to high Pd/Ir ratios and Ru anomalies for the Yinmin high-PGE samples and relatively lower Pd/lr ratios and Ru anomalies for the Lanniping low-PGE samples. We propose that the magmas parental to the Yinmin gabbroic dykes are initially S-unsaturated, and subsequently, minor evolved magma reached sulfur saturation and led to sulfide segregation. Although the Lanniping parental magmas are originally not saturated in S, the high Cu/Pd ratios (3.8× 10^4 to 3.2 × 10^6) for most of the Lanniping samples indicate the S-saturated state and sulfide segregation. A calculation shows that the PGE-poor magmas might have experienced 0.01%-0.1%sulfidesegregationinthemagma chamber. Therefore, our study provides a possible opportunity to discover PGE-enriched sulfide mineralization some- where near or within the Lanniping mafic intrusion.展开更多
With the continuous progress on affinity peptide research, it has become more and more popular in pharmacology and medicine. lt is promising to study these viruses affinity peptide to treat infectious diseases. And th...With the continuous progress on affinity peptide research, it has become more and more popular in pharmacology and medicine. lt is promising to study these viruses affinity peptide to treat infectious diseases. And the analysis on the virus affinity peptide with high selectivity and high sensitivity could provide valuable means for disease detection, treatment as wel as the study on the molecular mechanism of virus affinity peptide. Therefore, we reviewed the bioinformatics pre-diction technologies of computer simulation, molecular docking and homology model-ing, as wel as the research method on analyzing and screening virus affinity pep-tide, such as Phage display technology.展开更多
As part of the mosaic of micro-continents within the Central Asian Orogenic Belt(CAOB), the Xing’anAirgin Sum Block(XAB) features increasingly-recognized Meso-Neoproterozoic geological records. However, the origin, t...As part of the mosaic of micro-continents within the Central Asian Orogenic Belt(CAOB), the Xing’anAirgin Sum Block(XAB) features increasingly-recognized Meso-Neoproterozoic geological records. However, the origin, temporal-spatial distribution of ancient materials, and their roles in crust evolution remain to debate. This paper presents an integrated study of zircon U-Pb ages and Hf-O isotopes for Mesoproterozoic and Paleozoic granites from the Erenhot region of central Inner Mongolia, along eastern CAOB. The intrusion of 1450 Ma syenogranite denotes that the Precambrian basement of XAB extends from Sonid Zuoqi westward to Erenhot. The 384 and 281 Ma monzogranites containing Mesoproterozoic xenocrystic zircons possess Proterozoic-dominant two-stage Hf model ages, further suggesting the wide existence of Proterozoic crust beneath western XAB. Cyclic Proterozoic crustal growth and reworking seem to show close linkages with the orogenesis during relevant supercontinent cycles. 1450-1360 Ma juvenile crustal growth at Erenhot and synchronous ancient crust reworking at Sonid Zuoqi and Abagaqi were likely resulted from retreating subduction involved in Columbia breakup, while 1.2-1.0 Ga reworking and 0.9-0.7 Ga growth events within the Erenhot basement might respond to assembly and breakup of Rodinia, respectively. Besides, our work confirms that reworking of Neoproterozoic crust played important roles during Paleozoic multi-stage accretion of CAOB.展开更多
Vacuum ultraviolet(VUV)photoionization and photodissociation of methylcyclohexane have been studied utilizing a reflectron time-of-flight mass spectrometer(RTOF-MS)with synchrotron radiation source.Photoionization eff...Vacuum ultraviolet(VUV)photoionization and photodissociation of methylcyclohexane have been studied utilizing a reflectron time-of-flight mass spectrometer(RTOF-MS)with synchrotron radiation source.Photoionization efficiency curves(PIEs)of molecule ion C7H14^+ and fragment ions C7H13^+,C6H11^+,C6H10+,C5H10^+,C5H9^+,C4H8^+,C4H7^+,and C3H5^+ were observed.The ionization energy of methylcyclohexane was measured to be(9.80±0.03)eV,and appearance energies of fragment ions were determined from the PIEs.Optimized structures of transitional states,intermediates and product ions were characterized at the B3LYP/6-31G(d)level and the energies were calculated using G3B3 method.Formation channels of dominating fragment ions were proposed.Intramolecular hydrogen migrations and carbon ring-opening were the foremost processes in fragmentation pathways of methylcyclohexane.展开更多
The quantum phase transition in the isotropic XY chain with three-site interaction has been studied by calculating the quantum discord, classicai correlation, and concurrence measuring entanglement. It is found that t...The quantum phase transition in the isotropic XY chain with three-site interaction has been studied by calculating the quantum discord, classicai correlation, and concurrence measuring entanglement. It is found that the quantum discord is a better choice than concurrence to signal the presence of the quantum phase transition in this model, since that for next-nearest neighbor spins the derivative of the quantum discord still exhibits singularity at the critical point while there is no more entanglement.展开更多
Chinese rice wine making is a typical simultaneous saccharification and fermentation (SSF) process. During the fermentation process, temperature is one of the key parameters which decide the quality of Chinese rice ...Chinese rice wine making is a typical simultaneous saccharification and fermentation (SSF) process. During the fermentation process, temperature is one of the key parameters which decide the quality of Chinese rice wine. To optimize the SSF process for Chinese rice wine brewing, the effects of temperature on the kinetic parameters of yeast growth and ethanol production at various temperatures were determined in batch cultures using a mathematical model. The kinetic parameters as a function of temperature were evaluated using the software Origin8.0. Combing these functions with the mathematical model, an appropriate form of the model equations for the SSF considering the effects of temperature were developed. The kinetic parameters were found to fit the experimental data satisfactorily with the developed temperature-dependent model. The temperature profile for maximizing the ethanol production for rice wine fermentation was determined by genetic algorithm. The optimum temperature profile began at a low temperature of 26℃ up to 30 h. The operating temperature increased rapidly to 31.9 ℃, and then decreased slowly to 18℃ at 65 h. Thereafter, the temperature was maintained at 18 ℃ until the end of fermentation. A maximum ethanol production of 89.3 g.L 1 was attained. Conceivably, our model would facilitate the improvement of Chinese rice wine production at the industrial scale.展开更多
We categorify the notion of coalgebras by imposing a co-associative law up to some isomorphisms on the co-multiplication map and requiring that these isomorphisms satisfy certairl law of their own, which is called the...We categorify the notion of coalgebras by imposing a co-associative law up to some isomorphisms on the co-multiplication map and requiring that these isomorphisms satisfy certairl law of their own, which is called the copentagon identity. We also set up a 2-category of 2-coalgebras. The purpose of this study is from the idea of reconsidering the quasi-Hopf algebras by the categorification process, so that we can study the theory of quasi-Hopf algebras and their representations in some new framework of higher category theory in natural ways.展开更多
In various environmental studies, geoscience variables not only have the characteristics of time and space, but also are influenced by other variables. Multivariate spatiotemporal variables can improve the accuracy of...In various environmental studies, geoscience variables not only have the characteristics of time and space, but also are influenced by other variables. Multivariate spatiotemporal variables can improve the accuracy of spatiotemporal estimation. Taking the monthly mean ground observation data of the period 1960–2013 precipitation in the Xinjiang Uygur Autonomous Region, China, the spatiotemporal distribution from January to December in 2013 was respectively estimated by space-time Kriging and space-time CoKriging. Modeling spatiotemporal direct variograms and a cross variogram was a key step in space-time CoKriging. Taking the monthly mean air relative humidity of the same site at the same time as the covariates, the spatiotemporal direct variograms and the spatiotemporal cross variogram of the monthly mean precipitation for the period 1960–2013 were modeled. The experimental results show that the space-time CoKriging reduces the mean square error by 31.46% compared with the space-time ordinary Kriging. The correlation coefficient between the estimated values and the observed values of the space-time CoKriging is 5.07% higher than the one of the space-time ordinary Kriging. Therefore, a space-time CoKriging interpolation with air humidity as a covariate improves the interpolation accuracy.展开更多
Passive system theory was applied to propose a new passive control method with nonlinear observer of the Permanent Magnet Synchronous Motor chaotic system. Through constructing a Lyapunov function, the subsystem of th...Passive system theory was applied to propose a new passive control method with nonlinear observer of the Permanent Magnet Synchronous Motor chaotic system. Through constructing a Lyapunov function, the subsystem of the Permanent Magnet Synchronous Motor chaotic system could be proved to be globally stable at the equilibrium point. Then a controller with smooth state feedback is designed so that the Permanent Magnet Synchronous Motor chaotic system can be equivalent to a passive system. To get the state variables of the controller, the nonlinear observer is also studied. It is found that the outputs of the nonlinear observer can approximate the state variables of the Permanent Magnet Synchronous Motor chaotic system if the system’s nonlinear function is a globally Lipschitz function. Simulation results showed that the equivalent passive system of Permanent Magnet Synchronous Motor chaotic system could be globally asymptotically stabilized by smooth state feedback in the observed parameter convergence condition area.展开更多
OBJECTIVE To evaluate the clinical efficacy and toxicities of simultaneous modulated accelerated radiotherapy (SMART) and concurrent chemotherapy for locally advanced nasopharyngeal carcinoma. METHODS Eightyseven pa...OBJECTIVE To evaluate the clinical efficacy and toxicities of simultaneous modulated accelerated radiotherapy (SMART) and concurrent chemotherapy for locally advanced nasopharyngeal carcinoma. METHODS Eightyseven patients with nasopharyngeal carcinoma received SMART from April 2002 to September 2006. According to the UICC staging system, 30 patients were diagnosed as stage IIb, 42 patients stage III, 13 patients stage IVa and 2 patients stage IVb. The intensitymodulated radiotherapy was delivered with the "step and shoot" SMART technique with the prescribed dose of 66-76 Gy (2.2-2.4 Gy/day) to the gross tumor volume (GTV) and positive neck lymph nodes (GTVLN), with 60 Gy (2.0 Gy/day) to the highrisk clinical target volume (CTV1), encompassing the area around the nasopharynx and the upper neck, and with 54 Gy (1.8 Gy/day) to the lowrisk clinical target volume (CTV2), including the lower neck and supraclavicular area. Among all the patients, 31 received 2 cycles of SMART concurrently with 5 fluorouracil (5-Fu) and cisplatin (the FP group) and 56 received 2 cycles of concurrent cisplatin. All the patients received 3 to 4 cycles of adjuvant combination chemotherapy of cisplatin and 5fluorouracil starting from the 1st month after completion of SMART. RESULTS With a median follow up of 59 months (ranging from 19 to 85 months), the 1, 2 and 3year overall survival rates were 100%, 94.6% and 91.3% respectively. Acute mucositis and pharyngitis were more frequently observed in the FP group than in the cisplatin group. CONCLUSION SMART technique provides an excellent opportunity to spare normal tissue and is probably more biologically effective. Combination of single cisplatin was more tolerable.展开更多
The pyrolysis of n-butane and i-butane at low pressure was investigated from 823-1823 K in an electrically heated flow reactor using synchrotron vacuum ultraviolet photoionization mass spectrometry. More than 20 speci...The pyrolysis of n-butane and i-butane at low pressure was investigated from 823-1823 K in an electrically heated flow reactor using synchrotron vacuum ultraviolet photoionization mass spectrometry. More than 20 species, especially several radicals and isomers, were detected and identified from the measurements of photoionization efficiency (PIE) spectra. Based on the mass spectrometric analysis, the characteristics of n-butane and i-butane pyrolysis were discussed, which provided experimental evidences for the discussion of decomposition pathways of butane isomers. It is concluded that the isomeric structures of n-butane and i-butane have strong influence on their main decomposition pathways, and lead to dramatic differences in their mass spectra and PIE spectra such as the different dominant products and isomeric structures of butene products. Furthermore, compared with n-butane,i-butane can produce strong signals of benzene at low temperature in its pyrolysis due to the enhanced formation of benzene precursors like propargyl and C4 species, which provides experimental clues to explain the higher sooting tendencies of iso-alkanes than n-alkanes.展开更多
In order to improve the functional affinity of the humanized VH single domain antibody against human lung cancer, the genes coding the homogenous dimers dihu3D3Vn and tetramers tehu3D3VH were constructed by fusing the...In order to improve the functional affinity of the humanized VH single domain antibody against human lung cancer, the genes coding the homogenous dimers dihu3D3Vn and tetramers tehu3D3VH were constructed by fusing the SV5-Cys short peptide and p53 tetramefization structural domain gene to hu3D3VH gene via recombinant PCR technique, respectively. Then, the dihu3D3VH and tehu3D3VH genes were cloned to the prokaryotic expression vector pET-22b( + ) and expressed in E. coli BL21 (DE3). The proteins expressed were purified through Ni^2+ -affinity chromatographic column. Meanwhile, the hu3D3VH, dihu3D3VH and tehu3D3VH proteins were labeled with FTTC, and their reactivity with antigen and specificity were analyzed by immunofluorescence assay. As to their functional affinities, it was analyzed and compared by flow cytometry. The results indicated that these two genes were expressed as monomers and mainly as inclusion bodies. After purification and renaturation, there were about 50% of dimers and 70% of tetramer remaining in the protein solution. In addition, the dihu3D3VH and tehu3D3VH proteins still remained the reactivity with antigen and specificity of hu3D3VH protein, and their functional affinities were increased about 60% or 100% respectively, compared with those of hu3D3VH protein. It is evident that the functional affinity of hu3D3VH protein can be greatly improved by increasing its binding valency.展开更多
基金Natural Science Foundation of China (Grant No. 39900084)
文摘Basic structure and algorithm of leaf mechanism photosynthesis model were described in first part of this study based on former researcher results. Then, considering some environmental factors influencing on leaf photosynthesis, three numerical sensitivity experiments were carried out. We simulated the sing le leaf net CO2 assimilation, which acts as a function of different light, carbo n dioxide and temperature conditions. The relationships between leaf net photosy nthetic rate of C3 and C4 plant with CO2 concentration intercellular, leaf tempe rature, and photosynthetic active radiation (PAR) were presented, respectively. The results show the numerical experiment may indicate the main characteristic o f plant photosynthesis in C3 and C4 plant, and further can be used to integrate with the regional climate model and act as land surface process scheme, and bett er understand the interaction between vegetation and atmosphere.
基金Natural Science Foundation of China (Grant No. 39900084)
文摘Basic structure and algorithm of leaf mechanism photosynthesis model were described in first part of this study based on former researcher results. Then, considering some environmental factors influencing on leaf photosynthesis, three numerical sensitivity experiments were carried out. We simulated the sing le leaf net CO2 assimilation, which acts as a function of different light, carbo n dioxide and temperature conditions. The relationships between leaf net photosy nthetic rate of C3 and C4 plant with CO2 concentration intercellular, leaf tempe rature, and photosynthetic active radiation (PAR) were presented, respectively. The results show the numerical experiment may indicate the main characteristic o f plant photosynthesis in C3 and C4 plant, and further can be used to integrate with the regional climate model and act as land surface process scheme, and bett er understand the interaction between vegetation and atmosphere.
基金National Natural Science Foundation of China under Grant No.61379116,Natural Science Foundation of Hebei Province under Grant No.F2015203046 and No.F2013203124,Key Program of Research on Science and Technology of Higher Education Institutions of Hebei Province under Grant No.ZH2012028
文摘The existing collaborative recommendation algorithms have lower robustness against shilling attacks.With this problem in mind,in this paper we propose a robust collaborative recommendation algorithm based on k-distance and Tukey M-estimator.Firstly,we propose a k-distancebased method to compute user suspicion degree(USD).The reliable neighbor model can be constructed through incorporating the user suspicion degree into user neighbor model.The influence of attack profiles on the recommendation results is reduced through adjusting similarities among users.Then,Tukey M-estimator is introduced to construct robust matrix factorization model,which can realize the robust estimation of user feature matrix and item feature matrix and reduce the influence of attack profiles on item feature matrix.Finally,a robust collaborative recommendation algorithm is devised by combining the reliable neighbor model and robust matrix factorization model.Experimental results show that the proposed algorithm outperforms the existing methods in terms of both recommendation accuracy and robustness.
文摘Based on spontaneous desorption characteristic, the correlation of desorption time and gas content was analyzed and the application of it in production was researched. The desorption of high rank coalbed methane in Qinshui basin was periodic, and isotope fractionation effect also exists in the process. △δ^13C1 can be used to distinguish the stabilization of coalbed methane wells, associated with desorption rate, the individual well recoverable reserves can be calculated. Economically recoverable time can be predicted according to the logarithmic relationship between desorption gas content per ton and desorption time. The error between predicted result and numerical simulation result is only 1.5%.
基金Project (No. 10371107) supported by the National Natural Science Foundation of China
文摘Zhao (2003a) first established a congruence for any odd prime p〉3, S(1,1,1 ;p)=-2Bp-3 (mod p), which holds when p=3 evidently. In this paper, we consider finite triple harmonic sum S(α,β, γ,ρ) (modp) is considered for all positive integers α,β, γ. We refer to w=α+β+ γ as the weight of the sum, and show that if w is even, S(α,β, γ,ρ)=0 (mod p) for p≥w+3; if w is odd, S(α,β, γ,ρ)=-rBp-w (mod p) for p≥w, here r is an explicit rational number independent ofp. A congruence of Catalan number is obtained as a special case.
基金supported by the National Natural Science Foundation of China(41425011 and 41303016)
文摘Mafic intrusions and dykes are well preserved in the Yinmin and Lanniping districts, located within the western margin of the Yangtze Block, SW China. Although these mafic rocks from the two areas formed during different periods, they share similar ranges of PGE concentration. Most of the Yinmin gabbroic dykes contain relatively high PGE concentrations (PGEs=13.9-87.0 ppb) and low S contents (0.003 %-0.020 %), higher than the maximum PGE concentrations of mafic magmas melting from the mantle. Two exceptional Yinmin samples are characterized by relatively low PGE (PGEs = 0.31-0.37 ppb)and high S (0.114 %-0.257 %) contents. In contrast, most samples from the Lanniping gabbroic intrusion have low PGE con- centrations (PGEs = 0.12-1.02 ppb) and high S contents (0.130 %-0.360 %), except that the three samples exhibit relatively high PGE (PGEs=16.3-34.8 ppb) and low S concentrations (0.014 %-0.070 %). All the Yinmin and Lanniping samples are characterized by the enrichment of PPGE relative to IPGE in the primitive-mantle normalized diagrams, and the high-PGE samples exhibit obvious Ru anomalies. This study suggests that during the ascent of the parental magma, removal of Os-Ir-Ru alloys and/or chro- mite/spinel leads to high Pd/Ir ratios and Ru anomalies for the Yinmin high-PGE samples and relatively lower Pd/lr ratios and Ru anomalies for the Lanniping low-PGE samples. We propose that the magmas parental to the Yinmin gabbroic dykes are initially S-unsaturated, and subsequently, minor evolved magma reached sulfur saturation and led to sulfide segregation. Although the Lanniping parental magmas are originally not saturated in S, the high Cu/Pd ratios (3.8× 10^4 to 3.2 × 10^6) for most of the Lanniping samples indicate the S-saturated state and sulfide segregation. A calculation shows that the PGE-poor magmas might have experienced 0.01%-0.1%sulfidesegregationinthemagma chamber. Therefore, our study provides a possible opportunity to discover PGE-enriched sulfide mineralization some- where near or within the Lanniping mafic intrusion.
基金Supported by the Key Science and Technology Program of Henan Province(162102110136)the Science and Technology Fund for Outstanding Young People of Henan Academy of Agricultural Sciences(2016YQ28)~~
文摘With the continuous progress on affinity peptide research, it has become more and more popular in pharmacology and medicine. lt is promising to study these viruses affinity peptide to treat infectious diseases. And the analysis on the virus affinity peptide with high selectivity and high sensitivity could provide valuable means for disease detection, treatment as wel as the study on the molecular mechanism of virus affinity peptide. Therefore, we reviewed the bioinformatics pre-diction technologies of computer simulation, molecular docking and homology model-ing, as wel as the research method on analyzing and screening virus affinity pep-tide, such as Phage display technology.
基金Projects(41873035,41802053) supported by the National Natural Science Foundation of ChinaProject(ZD2021015) supported by the Science and Technology Project of Hebei Education Department,China+1 种基金Project(SCRM2116) supported by the Opening Foundation of Hebei Key Laboratory of Strategic Critical Mineral Resources,ChinaProject(202045004) supported by the Scientific Research Starting Foundation of Central South University,China。
文摘As part of the mosaic of micro-continents within the Central Asian Orogenic Belt(CAOB), the Xing’anAirgin Sum Block(XAB) features increasingly-recognized Meso-Neoproterozoic geological records. However, the origin, temporal-spatial distribution of ancient materials, and their roles in crust evolution remain to debate. This paper presents an integrated study of zircon U-Pb ages and Hf-O isotopes for Mesoproterozoic and Paleozoic granites from the Erenhot region of central Inner Mongolia, along eastern CAOB. The intrusion of 1450 Ma syenogranite denotes that the Precambrian basement of XAB extends from Sonid Zuoqi westward to Erenhot. The 384 and 281 Ma monzogranites containing Mesoproterozoic xenocrystic zircons possess Proterozoic-dominant two-stage Hf model ages, further suggesting the wide existence of Proterozoic crust beneath western XAB. Cyclic Proterozoic crustal growth and reworking seem to show close linkages with the orogenesis during relevant supercontinent cycles. 1450-1360 Ma juvenile crustal growth at Erenhot and synchronous ancient crust reworking at Sonid Zuoqi and Abagaqi were likely resulted from retreating subduction involved in Columbia breakup, while 1.2-1.0 Ga reworking and 0.9-0.7 Ga growth events within the Erenhot basement might respond to assembly and breakup of Rodinia, respectively. Besides, our work confirms that reworking of Neoproterozoic crust played important roles during Paleozoic multi-stage accretion of CAOB.
基金supported by the National Natural Science Foundation of China(No.91544105,No.41275127,No.U1532137 and No.11575178)。
文摘Vacuum ultraviolet(VUV)photoionization and photodissociation of methylcyclohexane have been studied utilizing a reflectron time-of-flight mass spectrometer(RTOF-MS)with synchrotron radiation source.Photoionization efficiency curves(PIEs)of molecule ion C7H14^+ and fragment ions C7H13^+,C6H11^+,C6H10+,C5H10^+,C5H9^+,C4H8^+,C4H7^+,and C3H5^+ were observed.The ionization energy of methylcyclohexane was measured to be(9.80±0.03)eV,and appearance energies of fragment ions were determined from the PIEs.Optimized structures of transitional states,intermediates and product ions were characterized at the B3LYP/6-31G(d)level and the energies were calculated using G3B3 method.Formation channels of dominating fragment ions were proposed.Intramolecular hydrogen migrations and carbon ring-opening were the foremost processes in fragmentation pathways of methylcyclohexane.
基金Supported by National Natural Science Foundation of China under Grant Nos. 11075013 and 10974016
文摘The quantum phase transition in the isotropic XY chain with three-site interaction has been studied by calculating the quantum discord, classicai correlation, and concurrence measuring entanglement. It is found that the quantum discord is a better choice than concurrence to signal the presence of the quantum phase transition in this model, since that for next-nearest neighbor spins the derivative of the quantum discord still exhibits singularity at the critical point while there is no more entanglement.
基金Supported by the National Natural Science Foundation of China(21276111,21206053,61305017)the Programme of Introducing Talents of Discipline to Universities(B12018)+2 种基金Fundamental Research Funds for the Central Universities(JUSRP11558)the Natural Science Foundation of Jiangsu Province(no.BK20160162)the Fundamental Research Funds for the Central Universities(JUSRP51510)
文摘Chinese rice wine making is a typical simultaneous saccharification and fermentation (SSF) process. During the fermentation process, temperature is one of the key parameters which decide the quality of Chinese rice wine. To optimize the SSF process for Chinese rice wine brewing, the effects of temperature on the kinetic parameters of yeast growth and ethanol production at various temperatures were determined in batch cultures using a mathematical model. The kinetic parameters as a function of temperature were evaluated using the software Origin8.0. Combing these functions with the mathematical model, an appropriate form of the model equations for the SSF considering the effects of temperature were developed. The kinetic parameters were found to fit the experimental data satisfactorily with the developed temperature-dependent model. The temperature profile for maximizing the ethanol production for rice wine fermentation was determined by genetic algorithm. The optimum temperature profile began at a low temperature of 26℃ up to 30 h. The operating temperature increased rapidly to 31.9 ℃, and then decreased slowly to 18℃ at 65 h. Thereafter, the temperature was maintained at 18 ℃ until the end of fermentation. A maximum ethanol production of 89.3 g.L 1 was attained. Conceivably, our model would facilitate the improvement of Chinese rice wine production at the industrial scale.
基金Supported by National Natural Science Foundation of China under Grant Nos. 10975102, 11031005 10871135, 10871227, and PHR201007107
文摘We categorify the notion of coalgebras by imposing a co-associative law up to some isomorphisms on the co-multiplication map and requiring that these isomorphisms satisfy certairl law of their own, which is called the copentagon identity. We also set up a 2-category of 2-coalgebras. The purpose of this study is from the idea of reconsidering the quasi-Hopf algebras by the categorification process, so that we can study the theory of quasi-Hopf algebras and their representations in some new framework of higher category theory in natural ways.
基金Project(17D02)supported by the Open Fund of State Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing,Wuhan University,ChinaProject supported by the State Key Laboratory of Satellite Navigation System and Equipment Technology,China
文摘In various environmental studies, geoscience variables not only have the characteristics of time and space, but also are influenced by other variables. Multivariate spatiotemporal variables can improve the accuracy of spatiotemporal estimation. Taking the monthly mean ground observation data of the period 1960–2013 precipitation in the Xinjiang Uygur Autonomous Region, China, the spatiotemporal distribution from January to December in 2013 was respectively estimated by space-time Kriging and space-time CoKriging. Modeling spatiotemporal direct variograms and a cross variogram was a key step in space-time CoKriging. Taking the monthly mean air relative humidity of the same site at the same time as the covariates, the spatiotemporal direct variograms and the spatiotemporal cross variogram of the monthly mean precipitation for the period 1960–2013 were modeled. The experimental results show that the space-time CoKriging reduces the mean square error by 31.46% compared with the space-time ordinary Kriging. The correlation coefficient between the estimated values and the observed values of the space-time CoKriging is 5.07% higher than the one of the space-time ordinary Kriging. Therefore, a space-time CoKriging interpolation with air humidity as a covariate improves the interpolation accuracy.
基金Project supported by the Natural Science Foundation of Zhejiang Province (No. Y104414) and the Science and Technology Plan of Zhejiang Province (No. 2005C21084), China
文摘Passive system theory was applied to propose a new passive control method with nonlinear observer of the Permanent Magnet Synchronous Motor chaotic system. Through constructing a Lyapunov function, the subsystem of the Permanent Magnet Synchronous Motor chaotic system could be proved to be globally stable at the equilibrium point. Then a controller with smooth state feedback is designed so that the Permanent Magnet Synchronous Motor chaotic system can be equivalent to a passive system. To get the state variables of the controller, the nonlinear observer is also studied. It is found that the outputs of the nonlinear observer can approximate the state variables of the Permanent Magnet Synchronous Motor chaotic system if the system’s nonlinear function is a globally Lipschitz function. Simulation results showed that the equivalent passive system of Permanent Magnet Synchronous Motor chaotic system could be globally asymptotically stabilized by smooth state feedback in the observed parameter convergence condition area.
文摘OBJECTIVE To evaluate the clinical efficacy and toxicities of simultaneous modulated accelerated radiotherapy (SMART) and concurrent chemotherapy for locally advanced nasopharyngeal carcinoma. METHODS Eightyseven patients with nasopharyngeal carcinoma received SMART from April 2002 to September 2006. According to the UICC staging system, 30 patients were diagnosed as stage IIb, 42 patients stage III, 13 patients stage IVa and 2 patients stage IVb. The intensitymodulated radiotherapy was delivered with the "step and shoot" SMART technique with the prescribed dose of 66-76 Gy (2.2-2.4 Gy/day) to the gross tumor volume (GTV) and positive neck lymph nodes (GTVLN), with 60 Gy (2.0 Gy/day) to the highrisk clinical target volume (CTV1), encompassing the area around the nasopharynx and the upper neck, and with 54 Gy (1.8 Gy/day) to the lowrisk clinical target volume (CTV2), including the lower neck and supraclavicular area. Among all the patients, 31 received 2 cycles of SMART concurrently with 5 fluorouracil (5-Fu) and cisplatin (the FP group) and 56 received 2 cycles of concurrent cisplatin. All the patients received 3 to 4 cycles of adjuvant combination chemotherapy of cisplatin and 5fluorouracil starting from the 1st month after completion of SMART. RESULTS With a median follow up of 59 months (ranging from 19 to 85 months), the 1, 2 and 3year overall survival rates were 100%, 94.6% and 91.3% respectively. Acute mucositis and pharyngitis were more frequently observed in the FP group than in the cisplatin group. CONCLUSION SMART technique provides an excellent opportunity to spare normal tissue and is probably more biologically effective. Combination of single cisplatin was more tolerable.
基金This work is supported by the National. Natural Science Foundation of China (No.51106146, No.51036007, No.U1232127), the China Postdoctoral Science Foundation (No.20100480047 and No.201104326), the Chinese Universities Scientific Fund (No.WK2310000010), the Anhui Science & Technology Department (No.l1040606Q49), and the Chinese Academy of Sciences.
文摘The pyrolysis of n-butane and i-butane at low pressure was investigated from 823-1823 K in an electrically heated flow reactor using synchrotron vacuum ultraviolet photoionization mass spectrometry. More than 20 species, especially several radicals and isomers, were detected and identified from the measurements of photoionization efficiency (PIE) spectra. Based on the mass spectrometric analysis, the characteristics of n-butane and i-butane pyrolysis were discussed, which provided experimental evidences for the discussion of decomposition pathways of butane isomers. It is concluded that the isomeric structures of n-butane and i-butane have strong influence on their main decomposition pathways, and lead to dramatic differences in their mass spectra and PIE spectra such as the different dominant products and isomeric structures of butene products. Furthermore, compared with n-butane,i-butane can produce strong signals of benzene at low temperature in its pyrolysis due to the enhanced formation of benzene precursors like propargyl and C4 species, which provides experimental clues to explain the higher sooting tendencies of iso-alkanes than n-alkanes.
文摘In order to improve the functional affinity of the humanized VH single domain antibody against human lung cancer, the genes coding the homogenous dimers dihu3D3Vn and tetramers tehu3D3VH were constructed by fusing the SV5-Cys short peptide and p53 tetramefization structural domain gene to hu3D3VH gene via recombinant PCR technique, respectively. Then, the dihu3D3VH and tehu3D3VH genes were cloned to the prokaryotic expression vector pET-22b( + ) and expressed in E. coli BL21 (DE3). The proteins expressed were purified through Ni^2+ -affinity chromatographic column. Meanwhile, the hu3D3VH, dihu3D3VH and tehu3D3VH proteins were labeled with FTTC, and their reactivity with antigen and specificity were analyzed by immunofluorescence assay. As to their functional affinities, it was analyzed and compared by flow cytometry. The results indicated that these two genes were expressed as monomers and mainly as inclusion bodies. After purification and renaturation, there were about 50% of dimers and 70% of tetramer remaining in the protein solution. In addition, the dihu3D3VH and tehu3D3VH proteins still remained the reactivity with antigen and specificity of hu3D3VH protein, and their functional affinities were increased about 60% or 100% respectively, compared with those of hu3D3VH protein. It is evident that the functional affinity of hu3D3VH protein can be greatly improved by increasing its binding valency.