Three major programs have been implemented in rural Tibetan areas in order to improve children's nutrition and healthcare,namely antenatal care,infant and young child feeding,as well as school feeding.In terms of ...Three major programs have been implemented in rural Tibetan areas in order to improve children's nutrition and healthcare,namely antenatal care,infant and young child feeding,as well as school feeding.In terms of effectiveness of service provision,the school feeding program has been put into practice more effectively than the other two for two reasons.First,rural Tibetan families are accustomed to traditional infant and young child feeding practices.Secondly,the lack of incentives for healthcare workers and the shortage of funding have hindered the provision of healthcare to rural families.Therefore,this paper proposes an adjustment of the incentive structure for healthcare providers,a fortification of the village level network of healthcare services,an improvement in the approach to healthcare education for farmers and herders,and the coordination of training courses targeted at the officials and service teams of the healthcare system.展开更多
Poultry and eggs are nutritious and healthy foods that contain high-quality proteins and low levels of fat compared with other meats. Recent studies have shown that poultry performance is closely associated with colon...Poultry and eggs are nutritious and healthy foods that contain high-quality proteins and low levels of fat compared with other meats. Recent studies have shown that poultry performance is closely associated with colonic health. Antibiotics are commonly used in the poultry industry to control diseases and enhance survival rates. However, antibiotic use can also result in host gut dysbiosis and immune dysregulation. Such imbalances compromise poultry health and growth performance. Thus, our study investigated the effect of Lactobacillus(L.) plantarum P-8 on the gut microbiome of chickens co-inoculated with the antibiotic lincomycin. Principal coordinate analysis showed that L. plantarum P-8 treatment shifted the faecal bacterial population structure. At the metagenomic level, the Clusters of Orthologous Groups(COGs) functional categories of P, C, N and A were overrepresented in the probiotic group. Additionally, the relative gene abundances of metabolic pathways involved in flagellar assembly,bacterial chemotaxis, nitrogen metabolism, sulfur metabolism, cofactor and vitamin biosynthesis were also higher in the probiotic group than the control; in contrast genes related to galactose degradation,carbon fixation, multiple sugar transport systems and ribosomes were underrepresented in the probiotic group. Our data suggest that feeding L. plantarum P-8 has the potential to improve metabolic activity and nutrient utilization of poultry. Furthermore, the faecal antibiotic resistomes of the two groups could be separated using principal components analysis, indicating that the probiotic treatment may modulate the intestinal antibiotic resistance gene pool by changing the population structure of the gut microbiota.This study has provided interesting insights into the application of probiotics in the poultry industry.展开更多
文摘Three major programs have been implemented in rural Tibetan areas in order to improve children's nutrition and healthcare,namely antenatal care,infant and young child feeding,as well as school feeding.In terms of effectiveness of service provision,the school feeding program has been put into practice more effectively than the other two for two reasons.First,rural Tibetan families are accustomed to traditional infant and young child feeding practices.Secondly,the lack of incentives for healthcare workers and the shortage of funding have hindered the provision of healthcare to rural families.Therefore,this paper proposes an adjustment of the incentive structure for healthcare providers,a fortification of the village level network of healthcare services,an improvement in the approach to healthcare education for farmers and herders,and the coordination of training courses targeted at the officials and service teams of the healthcare system.
文摘Poultry and eggs are nutritious and healthy foods that contain high-quality proteins and low levels of fat compared with other meats. Recent studies have shown that poultry performance is closely associated with colonic health. Antibiotics are commonly used in the poultry industry to control diseases and enhance survival rates. However, antibiotic use can also result in host gut dysbiosis and immune dysregulation. Such imbalances compromise poultry health and growth performance. Thus, our study investigated the effect of Lactobacillus(L.) plantarum P-8 on the gut microbiome of chickens co-inoculated with the antibiotic lincomycin. Principal coordinate analysis showed that L. plantarum P-8 treatment shifted the faecal bacterial population structure. At the metagenomic level, the Clusters of Orthologous Groups(COGs) functional categories of P, C, N and A were overrepresented in the probiotic group. Additionally, the relative gene abundances of metabolic pathways involved in flagellar assembly,bacterial chemotaxis, nitrogen metabolism, sulfur metabolism, cofactor and vitamin biosynthesis were also higher in the probiotic group than the control; in contrast genes related to galactose degradation,carbon fixation, multiple sugar transport systems and ribosomes were underrepresented in the probiotic group. Our data suggest that feeding L. plantarum P-8 has the potential to improve metabolic activity and nutrient utilization of poultry. Furthermore, the faecal antibiotic resistomes of the two groups could be separated using principal components analysis, indicating that the probiotic treatment may modulate the intestinal antibiotic resistance gene pool by changing the population structure of the gut microbiota.This study has provided interesting insights into the application of probiotics in the poultry industry.