国家规划如何有效保护社会?——基于改革开放40年中国社会保险发展历程的研究

国家规划是国家提供社会保护的一种方式,与法律型治理、指令型治理不同。学术界分别从整体性知识、地方性知识以及价格信号作用三个角度对规划治理的有效性进行论证。新中国成立以来就深受国家计划/规划这种管理方式的影响,尤其是改革开放后,国家计划在中国发生了根本性的转变,成为具有战略指导意义的国家规划。本文基于改革开放40年中国社会保险发展历程的分析,探讨国家规划如何有效促进社会保护。研究发现,在中国社会保险体系建设过程中,国家规划面临着发展重心的选择,尤其是在后发国家追赶的背景下,身份机制能够主导权利机制。国家规划在社会保护中既需要保护社会免受市场机制的全面侵扰,也需要利用市场在资源配置中的优势,以此增强国家财政能力和居民自我保障能力。国家规划目标的实现既要依赖科层制内部的高效协调,通过"放权"、"让利"调动地方政府的积极性,也要通过约束、考核等保证政策的执行。国家规划保护社会并非一劳永逸,需要一系列相契合的制度安排。

Online residual useful life prediction of large-size slewing bearings A data fusion method

To decrease breakdown time and improve machine operation reliability,accurate residual useful life(RUL) prediction has been playing a critical role in condition based monitoring.A data fusion method was proposed to achieve online RUL prediction of slewing bearings,which consisted of a reliability based RUL prediction model and a data driven failure rate(FR) estimation model.Firstly,an RUL prediction model was developed based on modified Weibull distribution to build the relationship between RUL and FR.Secondly,principal component analysis(PCA) was introduced to process multi-dimensional life-cycle vibration signals,and continuous squared prediction error(CSPE) and its time-domain features were employed as equipment performance degradation features.Afterwards,an FR estimation model was established on basis of the degradation features and relevant FRs using simplified fuzzy adaptive resonance theory map(SFAM) neural network.Consequently,real-time FR of equipment can be obtained through FR estimation model,and then accurate RUL can be calculated through the RUL prediction model.Results of a slewing bearing life test show that CSPE is an effective indicator of performance degradation process of slewing bearings,and that by combining actual load condition and real-time monitored data,the calculation time is reduced by 87.3%and the accuracy is increased by 0.11%,which provides a potential for online RUL prediction of slewing bearings and other various machineries.

Command and Control Cities in Global Space-economy Before and after 2008 Geo-economic Transition

The global economic downturn caused primarily by the US sub-prime mortgage crisis in 2007 engendered revenue loss of the multinational corporations. Existing studies have yet to depict the detrimental impacts on city＇s command and control functions induced by the sub-prime mortgage crisis together with its residual wave of global economic recession on the global spatial economy. Recent and previous studies have produced an ＇instant history＇ of the global spatial economy before the global economic downturn undermines the global economy in late 2008. How- ever, the waxes and wanes of major cities＇ command and control functions on the global economic arena before and after the outbreak of financial crisis and its associated geo-economic transitions are still poorly understood. This paper attempts to contribute a new set of customized data to update and fill in the gap in the literature with the investigation of the command and control functions of cities arotmd the world from 2005 to 2009. Particular attentions are paid to the time-space relationship of the geo-economic transition that can capture the recent historical images of the com- mand and control situation of different cities in the world.

RESEARCH OF PINYIN-TO-CHARACTER CONVERSION BASED ON MAXIMUM ENTROPY MODEL

This paper applied Maximum Entropy (ME) model to Pinyin-To-Character (PTC) conversion in-stead of Hidden Markov Model (HMM) that could not include complicated and long-distance lexical informa-tion. Two ME models were built based on simple and complex templates respectively, and the complex one gave better conversion result. Furthermore, conversion trigger pair of y A → y B cBwas proposed to extract the long-distance constrain feature from the corpus; and then Average Mutual Information (AMI) was used to se-lect conversion trigger pair features which were added to the ME model. The experiment shows that conver-sion error of the ME with conversion trigger pairs is reduced by 4% on a small training corpus, comparing with HMM smoothed by absolute smoothing.

Inhibitory effect of emodin and Astragalus polysaccharide on the replication of HBV

AIM: To evaluate the anti-viral effect of emodin plus Astragalus polysaccharide (APS) in hepatitis B virus (HBV) transgenic mice.METHODS: Sixty HBV transgenic mice (HBV TGM) whose weight varied between 18 and 24 g were randomly divided into 3 groups, with 20 mice in each group. Group A was the normal control, where the mice were treated with physiological saline; group B was the positive control where the mice were treated with lamivudine solution (100 mL/kg per day). Group C was the experimental group where the mice were treated with physiological saline containing emodin and APS (57.59 mg/kg per day and 287.95 mg/kg per day, respectively). The mice were treated daily for 3 wk. After 1 wk recovery time, the mice were sacrifi ced and serum as well as liver tissues were collected for ELISA and histological examination.RESULTS: After 21 d treatment, HBV DNA levels in group B and group C significantly declined when compared with group A (P < 0.05). However, a signif icant increase in HBV DNA content was observed in group B, whereas this phenomenon was not observed in group C. A reduction in the contents of HBsAg, HBeAg and HBcAg in the mice from group B and C was observed when compared with group A.CONCLUSION: Emodin and APS have a weak but persistent inhibitory effect on HBV replication in vivo, which may function as a supplementary modality in the treatment of hepatitis B infection.

Atmospheric radiative transfer simulation for at mospheric correction of remote sensing data

The radiance leaving the earth-atmosphere system which can be sensed by a satellite borne radiometer is the sum of radiation emission from the earth surface and each atmospheric level that are transmitted to the top of the atmosphere. The radiation emission from the earth surface and the radiance of each atmospheric level can be separated from the radiance at the top the atmospheric level measured by a satellite borne radiometer. However, it is very difficult to measure the atmospheric radiance, especially the synchronous measurement with the satellite. Thus some atmospheric radiative transfer models have been developed to provide many options for modeling atmospheric radiation transport, such as LOWTRAN, MODTRAN, 6S, FASCODE, LBLRTM, SHARC, and SAMM. Meanwhile, these models can support the detailed detector system design, the optimization and evaluation of satellite mission parameters, and the data processing procedures. As an example, the newly atmospheric radiative transfer models, MODTRAN will be compared with other models after the atmospheric radiative transfer is described. And the atmospheric radiative transfer simulation procedures and their applications to atmospheric transmittance, retrieval of atmospheric elements, and surface parameters, will also be presented.

Signal transduction mechanism of TRB3 in rats with non-alcoholic fatty liver disease

AIM： To evaluate the possible role of Tribble 3 （TRB3） in a rat model of non-alcoholic fatty liver disease （NAFLD） and its signal transduction mechanism.METHODS： Thirty Sprague-Dawley rats were randomized into three groups： normal control group, non-alcoholic fatty liver group A （fed on a high-fat diet for 8 wk） and group B （fed on a high-fat diet for 16 wk）. To determine the degree of hepatic steatosis in rats of each group, livers were stained with hematoxylin and eosin, and evaluated; real-time fluorescent quantitative reverse transcriptase-polymerase chain reaction was performed to measure the expression levels of TRI33 mRNA, and Western blotting analysis was done to determine the expression levels of protein kinase B （Akt） and phosphorylated protein kinase B （p-Akt-Thr308, p-Akt-Ser473）.RESULTS： Hepatic steatosis was evident in both NAFLD groups： mild to moderate hepatic steatosis occurred in group A, mainly as mild steatosis.Moderate to severe hepatic steatosis occurred in group B, mainly as severe steatosis. The expression level of TRB3 mRNA in group B was significantly higher than in the control group （122.28 ± 95.37 vs 3.06 ± 2.33,P = 0.002） and group A （122.28 ± 95.37 vs 5.77 ± 4.20,P = 0.001）. There was no significant difference in the expression levels of Akt （1.03 ± 0.53 vs 1.12 ± 0.77,P = 0.729） and p-Akt-Thr308 （0.82 ± 0.45 vs 0.92 ± 0.38, P = 0.592） between group A and the control group. The expression level of Akt and p-Akt-Thr308 in group B was significantly lower than in group A （Akt 0.41 ± 0.16 vs 1.12 ± 0.77, P = 0.008; p-Akt-Thr308 0.47 ± 0.19 vs 0.82 ± 0.45, P = 0.036） and the control group （Akt 0.41 ± 0.16 vs 1.03 ± 0.53, P = 0.018;p-Akt-Thr308 0.47 ± 0.19 vs 0.92 ± 0.38, P = 0.010）.The expression level of p-Akt-Ser473 in group A was significantly higher than in group B （1.48 ± 0.50 vs 0.81± 0.39, P = 0.041） as well as the control group （1.48 ± 0.50 vs 0.45 ± 0.26, P = 0.003）.CONCLUSION： TRB3 blocks insulin signaling by inhibiting Akt activation, which contributes to insulin resistance. It may be an important factor in the occurrence and development of NAFLD.

Factor Price Distortion and Conseq uential A dverse Wealth Transfers in China

As critical piece of China＇s gradualist economic transition, domestic price reform still faces major challenges. In particular, factor price, which is still tightlycontrolled and not market-based, is lower than market equilibrium price. Factor price distortion not only reduces market efficiency but also affects wealth distribution. Subsequent wealth transfer has, over the past ten to fifieen years, created a powerful vested interests and spawned social resentment, both of which may constitute major hazards in China＇s future reform and development. Keeping in mind that China will have to address factor price distortion in its next step of reform, this paper takes stock of China＇s journey toward price rejorm; examines the relationship among factor price distortion, previous economic growth, and policy; and estimates＇ the size of resulting wealth transfer.

Soil-Vegetation-Atmosphere Radiative Transfer Model in Microwave Region

The radiative transfer is one of the significant theories that describe the processes of scattering, emission, and absorption of electromagnetic radiant intensity through scattering medium. It is the basis of the study on the quan-titative remote sensing. In this paper, the radiative characteristics of soil, vegetation, and atmosphere were described respectively. The numerical solution of radiative transfer was accomplished by Successive Orders of Scattering (SOS). A radiative transfer model for simulating microwave brightness temperature over land surfaces was constructed, de-signed, and implemented. Analyzing the database generated from soil-vegetation-atmosphere radiative transfer model under Advanced Microwave Scanning Radiometer-Earth Observing System (AMSR-E) configuration showed that the atmospheric effects on microwave brightness temperature should not be neglected, particularly for higher frequency, and can be parameterized. At the same time, the relationship between the emissivities of the different channels was developed. The study results will promote the development of algorithm to retrieve geophysical parameters from mi-crowave remotely sensed data.

Readiness of a Developing Nation in Implementing Automation and Robotics Technologies in Construction： A Case Study of Malaysia

The Malaysian government＇s vision to be a developed nation by 2020 has pushed forward the use of innovative technologies in most sectors and industries, including the construction industry. Through the ETP （Economic Transformation Programme）, major projects launched are expected to provide a great catalyst for the economy, and may become the platform for increasing the use of automation and highly enhanced plants and machineries in the construction industry. Innovations in most countries are mostly driven by the need to find revolutionary solutions to problems, such as a shortage of skilled labor, decreasing quality of product and processes, inferior working conditions, declining productivity and increasing costs of labor and materials. Automation and robotics technologies encompass a wide range of innovative technologies using technologically advanced machineries to improve the speed and efficiency of a given process. This paper discusses the readiness of a developing country in embracing construction automation and robotics, by exploring industry perception, suggested practices and barriers to its implementation using a questionnaire survey and semi-structured interviews directed at Malaysian construction finns of contractors, specialist sub-contractors, developers and consultants. The findings show that the Malaysian construction industry is ready, to a certain extent, for implementing the technologies in limited areas such as prefabrication and assembly and in the design, planning and costing phases.

Effect of ONO-4057 and tacrolimus on ischemia-reperfusion injury of the liver

AIM: To investigate the effects of a novel Leukotriene B4 receptor antagonist and/or tacrolimus on ischemia-reperfusion in a rat liver model. METHODS: Male Lewis rats were pretreated with ONO-4057 (100 mg/kg) and/or tacrolimus (1 mg/kg) orally, and divided into four experimental groups; group 1 (control), group 2 (ONO-4057), group 3 (tacrolimus), group 4 (ONO-4057 + tacrolimus). RESULTS: There was a tendency for long survival in the groups treated with tacrolimus alone and ONO-4057 plus tacrolimus. Post-reperfusion serum aspartate aminotransferase levels decreased more signif icantly in ONO-4057 plus tacrolimus group (P < 0.01), than in the tacrolimus alone group (P < 0.05), compared to controls. CONCLUSION: This study demonstrated that pretreat-ment with ONO-4057 in combination with tacrolimus produced additive effects in a rat model of liver isch-emia-reperfusion injury.

基于智力城镇化的特色小镇产业培育探索——以辽宁通远堡镇为例

我国城镇化正处于劣势的体力城镇化阶段,特色小镇作为新型城镇化的主力军,体力化威胁仍不可避免。为缓解特色小镇体力化困境,文章基于智力城镇化的相关理论,以辽宁通远堡镇为例,围绕特色产业展开智力化培育的探索。结合链式产业思维,以智力投入、智力主体、智力产出三大环节为基础,以智力要素创新性地打造智力链条,构建可持续的特色产业,带动城镇化转型升级,以期为辽宁省乃至全国特色小镇培育提供借鉴。

The transformation of College English in China

The key factors that pushed College English in China to the stage of transformation are:globalization,student challenges,expansion of enrolment and primary and high school coordination challenge.The theoretical frameworks should cover the concepts of communicative competence,the learning-centered approach and learner autonomy.It then describes the major areas affected by the transformation to a new CE,in which the primary objective is to develop students’English comprehension and communicative competence:the nature and goal of the curriculum,curriculum requirements,teaching mode,assessment,and administration,In the new CE,focus has shifted from reading to listening and speaking,and special attention is now given to independent learning by capitalizing on advanced information technology;five principles are understood as the underpinnings of the transformation:a shift in orientation towards competence,the dominance of learning,focus on process,emphasis on culture,and increasingly democratic learning.

Land Collectivization and the Structural Transformation of Traditional Rural Families

We use oral history materials from elderly rural people aged over seventy to analyze the circumstances of rural family production and daily life prior to collectivization in the mid- 1950s; during collectivization in the 1950s to the 1970s; and under the household contract responsibility system of the late 1970s. We find that the transition from the traditional to the nuclear family did not involve industrialization in the traditional Western sense. As an early state industrialization strategy after 1949, rural collectivization fundamentally changed the organizational pattern of traditional family production and daily life and of inter-generational relations and structures under the patriarchal system, launching the historical process of structural transition in the family. This explanation differs from the classic ＂theory of modernization＂ of family change.

Generation of obese rat model by transcription activator-like effector nucleases targeting the leptin receptor gene

The laboratory rat is a valuable mammalian model organism for basic research and drug discovery. Here we demonstrate an efficient methodology by applying transcription activator-like effector nucleases(TALENs) technology to generate Leptin receptor(Lepr) knockout rats on the Sprague Dawley(SD) genetic background. Through direct injection of in vitro transcribed m RNA of TALEN pairs into SD rat zygotes, somatic mutations were induced in two of three resulting pups. One of the founders carrying bi-allelic mutation exhibited early onset of obesity and infertility. The other founder carried a chimeric mutation which was efficiently transmitted to the progenies. Through phenotyping of the resulting three lines of rats bearing distinct mutations in the Lepr locus, we found that the strains with a frame-shifted or premature stop codon mutation led to obesity and metabolic disorders. However, no obvious defect was observed in a strain with an in-frame 57 bp deletion in the extracellular domain of Lepr. This suggests the deleted amino acids do not significantly affect Lepr structure and function. This is the first report of generating the Lepr mutant obese rat model in SD strain through a reverse genetic approach. This suggests that TALEN is an efficient and powerful gene editing technology for the generation of disease models.

The Rise and Impact of Financial Capitalism:A Sociological Analysis of New Forms of Capitalism

Compared with Karl Polanyi’s first Great Transformation,the emergence of the even more influential financial capitalism can be called the second Great Transformation.The global expansion of financial capitalism has extended its power beyond the remit of nation-states as governments,firms,families and individuals are increasingly guided and reshaped by financial markets,producing a trend toward the financialization of social life.An important social consequence is the ever more marked separation of financial markets from society,a separation that has gradually eroded the power of the state,trade unions and civil society and aggravated the employment crises,the polarization of rich and poor and the structural inequality of developed capitalist countries.In the face of society’s erosion by financial capital,the West has taken measures of social self-protection,but these have so far had little effect.To establish a new financial and market governance structure at the global level that will effectively cope with the negative impact of financial capitalism is a long and arduous task.

Effects of Sijunzi decoction and Yupingfeng powder on expression of janus kinase-signal transducer and activator of transcription signal pathway in the brain of spleen-deficiency model rats

OBJECTIVE： To observe the influence of Sijunzi decoction and Yupingfeng powder on the expression of the relevant DNAs of janus kinase （JAK）-signal transducer and activator of transcription （STAT） sig- nal pathway of the brain in spleen-deficiency mod- el rats. METHODS： Eighty male Wistar rats of sanitary degree were divided randomly into four groups： nor- mal group, model group, treatment group 1, treatment group 2. Besides the rats in the normal group, all the rats in other 3 groups were prepared as spleen deficiency model. The treatment group 1 were treated with Sijunzi decoction and the treat- ment group 2 were treated with Yupingfeng powder. After treatment for 6 weeks, perfusion was given and the brain was taken for detection of the ex- pression of the relevant DNAs of JAK-STAT signal pathwayofthe brain in SD rats bygene chip method. RESULTS： Spleen deficiency could lead to increase expression of JAKI, STATI and Interleukin 4 （IL-4） in the brain, but the decrease expression of Suppres- sor of cytokine signaling I （SOCSI）, prolactin recep- tor （PRLR） and binding protein 3 （GATA 3）. Sijunzi decoction could increase expression of STAT3, Pro- lactin （PRL） and GATA3, but decrease expression of JAKI, STAT, STAT4, Interleukin 10 receptor, alpha （ILIORA）, Coagulation factor II （F2）, PRLR, MAD homolog 3 （SMAD3） and IL-4. Yupingfeng powder could decrease expression of JAKI, STATI, STAT4, SOCS4_ predicted, Epidermal growth factor receptor （EGFR）, PRLR, High mobility group AT-hook I （HMGAI 0）, IL-4. CONCLUSION： Sijunzi decoction and Yupingfeng powder can improve immune function of the rat through influencing the genetic expression of JAK-STAT signal pathway.

Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-β in rats with unilateral ureteral obstruction

Astragalus mongholicus （AM） derived from the dry root ofAstragalus membranaceus Bge. var. mongolicus （Bge.） Hsiao is a widely used traditional Chinese medicine. The present study investigated the potential role of AM on renal fibrosis on a rat model of unilateral ureteral obstruction （UUO）. We divided 48 Sprague-Dawley rats randomly into 4 groups： sham-operated group （Sham）, untreated UUO group, AM-treated （10 g/（kg.d）） UUO group, and losartan-treated （20 mg/（kg.d）） UUO group as positive control. Haematoxylin ＆ eosin （HE） and Masson staining were used to study the dynamic histological changes of the kidneys 7 and 14 d after operation. The expressions of fibronectin （FN）, type I collagen （coil）, hepatocyte growth factor （HGF）, transforming growth factor-β1 （TGF-β1）, and eL-smooth muscle actin （α-SMA） were analyzed by real-time polymerase chain reaction （PCR）, immunohistochemistry staining, and Western blot. Results show that, similar to losartan, AM alleviated the renal damage and decreased the deposition of FN and coil from UUO by reducing the expressions of TGF-β1 and α-SMA （P〈0.05）, whereas HGF increased greatly with AM treatment （P〈0.05）. Our findings reveal that AM could retard the progression of renal fibrosis. The renoprotective effect of AM might be related to inhibition ofmyofibroblast activation, inducing of HGF and reducing of TGF-β1 expression.

Effects of Bushen Huoxue Yin(补肾活血饮) on brain NF-κB and NO content in the parkinson's disease model mouse

OBJECTIVE:To observe the effects of Bushen Huoxue Yin(补肾活血饮,BSHXY) on nuclear transcription factor kappa B(NF-κB) and nitric oxide(NO) in the brain of the Parkinson's disease(PD) model mouse.METHODS:Forty-five C57BL/6 mice were randomly divided into three groups;normal,model and BSHXY treatment groups.Concentrations of NF-κB and NO in mouse brain tissue were determined by ELISA and spectrophotometry,respectively.RESULTS:NF-κB concentration in brain tissue in the model group was 14.04±4.38 μg· L-1,which was higher than that in normal(P<0.01) and BSHXY(P< 0.05) groups.NO content in brain tissue in the model group was 5.93±0.79 μmol · gprot-1,which was also higher than that in model(P<0.01) and BSHXY(P<0.01) groups.However,there were no significant differences in the content of NF-κB and NO between BSHXY and normal groups(P>0.05).CONCLUSION:The mechanism of BSHXY for treatment of PD is possibly related to inhibition ofNF-κB activation and decreased NO content in the brain.

Interpreting and considering the development of the goal orientation in the transformation of Chinese normal universities

As the teacher education in China gradually evolves from the closed one into an open one,and with the greater pressure from the competition among universities,the transformation of normal universities is an inevitable choice.The problems that normal universities need to face up to are the proper goal orientation and the setting of appropriate development goals.Through the comparison and interpretation of the development goals of current normal universities in China,this paper finds similar tendency in the development types and the choices of features.Goal orientation is vital to the development of normal universities.Therefore,when setting and implementing development goals,a sound understanding about expressions like“the features of operating schools”and“comprehensive universities”should be improved,and a rational thinking about the fundamental questions should be engaged in as well.