In order to price European contingent claim in a class of fractional Black-Scholes market, where the prices of assets follow a Wick-Ito stochastic differential equation driven by the fractional Brownian motion and mar...In order to price European contingent claim in a class of fractional Black-Scholes market, where the prices of assets follow a Wick-Ito stochastic differential equation driven by the fractional Brownian motion and market coefficients are deterministic functions, the pricing formula of European call option was explicitly derived by the method of the stochastic calculus of tile fractional Brownian motion. A result about fractional Clark derivative was also obtained.展开更多
Objective To investigate the risk factors of symptomatic bradyarrhythrnias in relation to β-blockers use. Methods A hospital-based case-control study [228 patients： 108 with symptomatic bradyarrhythmias （cases） an...Objective To investigate the risk factors of symptomatic bradyarrhythrnias in relation to β-blockers use. Methods A hospital-based case-control study [228 patients： 108 with symptomatic bradyarrhythmias （cases） and 120 controls] was conducted in Sultanah Aminah Hospital, Malaysia between January 2011 and January 2014. Results The mean age was 61.1 ~ 13.3 years with a majority of men （68.9%）. Cases were likely than control to be older, hypertensive, lower body mass index and concomitant use of rate-controlling drugs （such as digoxin, verapamil, diltiazem, ivabradine or amiodarone）. Significantly higher level of serum potassium, urea, creatinine and lower level of estimated glomerular filtration rate （eGFR） were observed among cases as compared to controls. On univariate analysis among patients on β-blockers, older age （crude OR： 1.07; 95% CI： 1.03-1.11, P = 0.000）, hypertension （crude OR： 5.6; 95% CI： 1.51-20.72, P = 0.010）, lower sodium （crude OR： 0.04; 95% CI： 0.81-0.99, P = 0.036）, higher potassium （crude OR： 2.36; 95% CI： 1.31-4.26, P = 0.004） and higher urea （crude OR： 1.23; 95% CI： 1.11-1.38, P = 0.000） were associated with increased risk of symptomatic bradyarrhythmias; eGFR was inversely and significantly associated with symptomatic bradyarrhythmias in both ＇β-blockers＇ （crude OR： 0.97; 95% CI： 0.964）.98, P = 0.000） and ＇non-β-blockers＇ （crude OR： 0.99; 95% CI： 0.97-0.99, P = 0.023） arms. However, eGFR was not significantly associated with symptomatic bradyarrhythmias in the final model of both ＇β-blockers＇ （adjusted OR： 0.98; 95% CI： 0.96-0.98, P = 0.103） and ＇non-p-blockers＇ （adjusted OR： 0.99; 95% CI： 0.97-1.01, P = 0.328） arms. Importantly, older age was a significant predictor of symptomatic bradyarrhythmias in the ＇β-blockers＇ as compared to the ＇non-β-blockers＇ arms （adjusted OR： 1.09; 95% CI： 1.03-1.15, P = 0.003 vs. adjusted OR： 1.03; 95% CI： 0.98-1.09, P = 0.232, respectively）. Conclusion Older age was a significant predictor of symptomatic bradyarrhythmias in patients on β-blockers than those without β-blockers.展开更多
Experimental research has recently shown that acupuncture induces the formation of opioid-like peptides (OLPs) in animals. In order to provide further evidence, we tested the beta-endorphin levels and other parameters...Experimental research has recently shown that acupuncture induces the formation of opioid-like peptides (OLPs) in animals. In order to provide further evidence, we tested the beta-endorphin levels and other parameters (VIP, lymphocyte subsets, NK cells and monocyte phagocytosis) in a group of 90 patients suffering from various painful disorders treated with acupuncture. Zusanli (St 36) and Hegu (LI 4) acupoints were selected. A homogeneous group of 30 subjects was used as control. Evaluation of the above parameters was made with 3 series of blood tests before treatment, 30 minutes and 24 hours after acupuncture treatment. In the acupuncture group, the following results were achieved: 1) A considerable increase in beta-endorphin levels remained high even 24 hours after acupuncture treatment. In addition, we demonstrated an inverted correlation between beta-endorphins and VIP; 2) 30 minutes after acupuncture session, 80% of the treated patients showed a significant increase of CD3 and CD4 values and an increase of CD8 24 hours after stimulation; 3) Monocyte phagocytosis was increased in 45% of the treated subjects 30 minutes from starting treatment, and in 100% of them after 24 hours. The percentage of NK cells was also increased in 40% of cases after 30 minutes, and in 50% after 24 hours. However, in the control group, no such significant changes in immune parameters were found.展开更多
Based on the kairomone from the accessory gland of female Bombyx mori elicting the parasitoid, Telenomus theophilae, to parasitize artifical beads. A cDNA expression library of enrich kairomone gene was constr...Based on the kairomone from the accessory gland of female Bombyx mori elicting the parasitoid, Telenomus theophilae, to parasitize artifical beads. A cDNA expression library of enrich kairomone gene was constructed using mRNA rich secretory portion of the accessory glands of B. mori at the 9 day old of pupa. The titer of the unamplified library was 3.29×10 4 pfu/μL with a recombinant rate of 90.05%, and titer of amplified library was 1.56×10 7 pfu/μL. The inserted cDNA fragments of the library ranged from 0.5 to 8.0 kb and concentrated around the 2.5 kb, 1.1kb, and 0.75kb regions. All of the data suggest that the library has appropriate titer and high frequency kairomone gene fragments by using special developing stage and tissue of B. mori to extract mRNA. Directional cloning and λZiplox expression were help to clone the kairomone gene with immunoscreening.展开更多
To accelerate the breeding process of cultivated Ophiocordyceps sinensis and increase its yield,it is important to identify molecular fingerprint of dominant O.sinensis.In the present study,we collected 3 batches of i...To accelerate the breeding process of cultivated Ophiocordyceps sinensis and increase its yield,it is important to identify molecular fingerprint of dominant O.sinensis.In the present study,we collected 3 batches of industrially cultivated O.sinensis product with higher yield than the others and compared their internal transcribed spacer(ITS)sequences with the wild and the reported.The ITS sequence was obtained by bidirectional sequencing and analyzed with molecular systematics as a DNA barcode for rapid and accurate identification of wild and cultivated O.sinensis collected.The ITS sequences of O.sinensis with detailed collection loci on NCBI were downloaded to construct a phylogenetic tree together with the sequences obtained from the present study by using neighbor-joining method based on their evolution relationship.The information on collection loci was analyzed with ArcGIS 10.2 to demonstrate the geographic distribution of these samples and thus to determine the origin of the dominant samples.The results showed that all wild and cultivated samples were identified as O.sinensis and all sequences were divided into seven phylogenetic groups in the tree.Those groups were precisely distributed on the map and the process of their system evolution was clearly presented.The three cultivated samples were clustered into two dominant groups,showing the correlation between the industrially cultivated samples and the dominant wild samples,which can provide references for its optimized breeding in the future.展开更多
In most of the predator-prey systems, prey individuals make transitions between vulnerable and invulnerable states or locations. This transition is regulated by various inducible defense mechanisms. Diel vertical migr...In most of the predator-prey systems, prey individuals make transitions between vulnerable and invulnerable states or locations. This transition is regulated by various inducible defense mechanisms. Diel vertical migration （DVM） in zooplankton is the most effective and instantaneous defense observed in zooplankton population. Zooplankton shows downward vertical migration in the daytime in the presence of predators （or predator kairomones） to avoid predation （i.e. refuge use）, and it enters into the surface water again at night to graze phytoplankton. The dynamics of the planktonic ecosystem under DVM of zooplankton along with fish kairomone and the multiple delays due to migration for vulnerable and invulnerable prey and reproduction in the predator population is of considerable interest both in theoretical and experimental ecologists. By developing mathematical model, we analyze such a system. The conditions for which the system enters into Hopf-bifurcation are obtained. Moreover, the conditions for which the bifurcating branches are supercritical are also derived. Our results indicate that DVM along with the effect of kairomone and multiple delays with a certain range are responsible to enhance the stability of the system around the positive interior equilibrium point.展开更多
基金National Natural Science Foundation of China(No.10826098)Natural Science Foundation of Anhui Province,China(No.090416225)Anhui Natural Science Foundation of Universities,China(No.KJ2010A037)
文摘In order to price European contingent claim in a class of fractional Black-Scholes market, where the prices of assets follow a Wick-Ito stochastic differential equation driven by the fractional Brownian motion and market coefficients are deterministic functions, the pricing formula of European call option was explicitly derived by the method of the stochastic calculus of tile fractional Brownian motion. A result about fractional Clark derivative was also obtained.
文摘Objective To investigate the risk factors of symptomatic bradyarrhythrnias in relation to β-blockers use. Methods A hospital-based case-control study [228 patients： 108 with symptomatic bradyarrhythmias （cases） and 120 controls] was conducted in Sultanah Aminah Hospital, Malaysia between January 2011 and January 2014. Results The mean age was 61.1 ~ 13.3 years with a majority of men （68.9%）. Cases were likely than control to be older, hypertensive, lower body mass index and concomitant use of rate-controlling drugs （such as digoxin, verapamil, diltiazem, ivabradine or amiodarone）. Significantly higher level of serum potassium, urea, creatinine and lower level of estimated glomerular filtration rate （eGFR） were observed among cases as compared to controls. On univariate analysis among patients on β-blockers, older age （crude OR： 1.07; 95% CI： 1.03-1.11, P = 0.000）, hypertension （crude OR： 5.6; 95% CI： 1.51-20.72, P = 0.010）, lower sodium （crude OR： 0.04; 95% CI： 0.81-0.99, P = 0.036）, higher potassium （crude OR： 2.36; 95% CI： 1.31-4.26, P = 0.004） and higher urea （crude OR： 1.23; 95% CI： 1.11-1.38, P = 0.000） were associated with increased risk of symptomatic bradyarrhythmias; eGFR was inversely and significantly associated with symptomatic bradyarrhythmias in both ＇β-blockers＇ （crude OR： 0.97; 95% CI： 0.964）.98, P = 0.000） and ＇non-β-blockers＇ （crude OR： 0.99; 95% CI： 0.97-0.99, P = 0.023） arms. However, eGFR was not significantly associated with symptomatic bradyarrhythmias in the final model of both ＇β-blockers＇ （adjusted OR： 0.98; 95% CI： 0.96-0.98, P = 0.103） and ＇non-p-blockers＇ （adjusted OR： 0.99; 95% CI： 0.97-1.01, P = 0.328） arms. Importantly, older age was a significant predictor of symptomatic bradyarrhythmias in the ＇β-blockers＇ as compared to the ＇non-β-blockers＇ arms （adjusted OR： 1.09; 95% CI： 1.03-1.15, P = 0.003 vs. adjusted OR： 1.03; 95% CI： 0.98-1.09, P = 0.232, respectively）. Conclusion Older age was a significant predictor of symptomatic bradyarrhythmias in patients on β-blockers than those without β-blockers.
文摘Experimental research has recently shown that acupuncture induces the formation of opioid-like peptides (OLPs) in animals. In order to provide further evidence, we tested the beta-endorphin levels and other parameters (VIP, lymphocyte subsets, NK cells and monocyte phagocytosis) in a group of 90 patients suffering from various painful disorders treated with acupuncture. Zusanli (St 36) and Hegu (LI 4) acupoints were selected. A homogeneous group of 30 subjects was used as control. Evaluation of the above parameters was made with 3 series of blood tests before treatment, 30 minutes and 24 hours after acupuncture treatment. In the acupuncture group, the following results were achieved: 1) A considerable increase in beta-endorphin levels remained high even 24 hours after acupuncture treatment. In addition, we demonstrated an inverted correlation between beta-endorphins and VIP; 2) 30 minutes after acupuncture session, 80% of the treated patients showed a significant increase of CD3 and CD4 values and an increase of CD8 24 hours after stimulation; 3) Monocyte phagocytosis was increased in 45% of the treated subjects 30 minutes from starting treatment, and in 100% of them after 24 hours. The percentage of NK cells was also increased in 40% of cases after 30 minutes, and in 50% after 24 hours. However, in the control group, no such significant changes in immune parameters were found.
文摘Based on the kairomone from the accessory gland of female Bombyx mori elicting the parasitoid, Telenomus theophilae, to parasitize artifical beads. A cDNA expression library of enrich kairomone gene was constructed using mRNA rich secretory portion of the accessory glands of B. mori at the 9 day old of pupa. The titer of the unamplified library was 3.29×10 4 pfu/μL with a recombinant rate of 90.05%, and titer of amplified library was 1.56×10 7 pfu/μL. The inserted cDNA fragments of the library ranged from 0.5 to 8.0 kb and concentrated around the 2.5 kb, 1.1kb, and 0.75kb regions. All of the data suggest that the library has appropriate titer and high frequency kairomone gene fragments by using special developing stage and tissue of B. mori to extract mRNA. Directional cloning and λZiplox expression were help to clone the kairomone gene with immunoscreening.
基金supported by the Macao Science and Technology Development Fund(No.062/2017/A2)
文摘To accelerate the breeding process of cultivated Ophiocordyceps sinensis and increase its yield,it is important to identify molecular fingerprint of dominant O.sinensis.In the present study,we collected 3 batches of industrially cultivated O.sinensis product with higher yield than the others and compared their internal transcribed spacer(ITS)sequences with the wild and the reported.The ITS sequence was obtained by bidirectional sequencing and analyzed with molecular systematics as a DNA barcode for rapid and accurate identification of wild and cultivated O.sinensis collected.The ITS sequences of O.sinensis with detailed collection loci on NCBI were downloaded to construct a phylogenetic tree together with the sequences obtained from the present study by using neighbor-joining method based on their evolution relationship.The information on collection loci was analyzed with ArcGIS 10.2 to demonstrate the geographic distribution of these samples and thus to determine the origin of the dominant samples.The results showed that all wild and cultivated samples were identified as O.sinensis and all sequences were divided into seven phylogenetic groups in the tree.Those groups were precisely distributed on the map and the process of their system evolution was clearly presented.The three cultivated samples were clustered into two dominant groups,showing the correlation between the industrially cultivated samples and the dominant wild samples,which can provide references for its optimized breeding in the future.
文摘In most of the predator-prey systems, prey individuals make transitions between vulnerable and invulnerable states or locations. This transition is regulated by various inducible defense mechanisms. Diel vertical migration （DVM） in zooplankton is the most effective and instantaneous defense observed in zooplankton population. Zooplankton shows downward vertical migration in the daytime in the presence of predators （or predator kairomones） to avoid predation （i.e. refuge use）, and it enters into the surface water again at night to graze phytoplankton. The dynamics of the planktonic ecosystem under DVM of zooplankton along with fish kairomone and the multiple delays due to migration for vulnerable and invulnerable prey and reproduction in the predator population is of considerable interest both in theoretical and experimental ecologists. By developing mathematical model, we analyze such a system. The conditions for which the system enters into Hopf-bifurcation are obtained. Moreover, the conditions for which the bifurcating branches are supercritical are also derived. Our results indicate that DVM along with the effect of kairomone and multiple delays with a certain range are responsible to enhance the stability of the system around the positive interior equilibrium point.
