In order to deal with modeling problem of a pressure balance system with time-delay, nonlinear, time-varying and uncertain characteristics, an intelligent modeling procedure is proposed, which is based on artificial n...In order to deal with modeling problem of a pressure balance system with time-delay, nonlinear, time-varying and uncertain characteristics, an intelligent modeling procedure is proposed, which is based on artificial neural network(ANN) and input-output data of the system during shield tunneling and can overcome the precision problem in mechanistic modeling(MM) approach. The computational results show that the training algorithm with Gauss-Newton optimization has fast convergent speed. The experimental investigation indicates that, compared with mechanistic modeling approach, intelligent modeling procedure can obviously increase the precision in both soil pressure fitting and forecasting period. The effectiveness and accuracy of proposed intelligent modeling procedure are verified in laboratory tests.展开更多
The patterns of EEG will change with mental tasks performed by the subject. In the field of EEG signal analysis and application, the study to get the patterns of mental EEG and then to use them to classify mental task...The patterns of EEG will change with mental tasks performed by the subject. In the field of EEG signal analysis and application, the study to get the patterns of mental EEG and then to use them to classify mental tasks has the significant scientific meaning and great application value. But for the reasons of different artifacts existing in EEG, the pattern detection of EEG under normal mental states is a very difficult problem. In this paper, Independent Component Analysis is applied to EEG signals collected from performing different mental tasks .The experiment results show that when one subject performs a single mental task in different trials, the independent components of EEG are very similar. It means that the independent components can be used as the mental EEG patterns to classify the different mental tasks.展开更多
Autism is a complex neuropsychiatric disorder of developmental origin, where multiple genetic and environmental factors likely interact resulting in a clinical continuum between "affected" and "unaffect...Autism is a complex neuropsychiatric disorder of developmental origin, where multiple genetic and environmental factors likely interact resulting in a clinical continuum between "affected" and "unaffected" individuals in the general population. During the last two decades, relevant progress has been made in identifying chromosomal regions and genes in linkage or association with autism, but no single gene has emerged as a major cause of disease in a large number of patients. The purpose of this paper is to discuss specific methodological issues and experimental strategies in autism genetic research, based on fourteen years of experience in patient recruitment and association studies of autism spectrum disorder in Italy.展开更多
基金Project(2013CB035402) supported by the National Basic Research Program of ChinaProjects(51105048,51209028) supported by the National Natural Science Foundation of China
文摘In order to deal with modeling problem of a pressure balance system with time-delay, nonlinear, time-varying and uncertain characteristics, an intelligent modeling procedure is proposed, which is based on artificial neural network(ANN) and input-output data of the system during shield tunneling and can overcome the precision problem in mechanistic modeling(MM) approach. The computational results show that the training algorithm with Gauss-Newton optimization has fast convergent speed. The experimental investigation indicates that, compared with mechanistic modeling approach, intelligent modeling procedure can obviously increase the precision in both soil pressure fitting and forecasting period. The effectiveness and accuracy of proposed intelligent modeling procedure are verified in laboratory tests.
基金This research is supported by National Nature Science Foundation of China (6 0 2 710 2 4 ) and Nature Science Foundation of Anhuiprovince(0 0 4 32 14 )
文摘The patterns of EEG will change with mental tasks performed by the subject. In the field of EEG signal analysis and application, the study to get the patterns of mental EEG and then to use them to classify mental tasks has the significant scientific meaning and great application value. But for the reasons of different artifacts existing in EEG, the pattern detection of EEG under normal mental states is a very difficult problem. In this paper, Independent Component Analysis is applied to EEG signals collected from performing different mental tasks .The experiment results show that when one subject performs a single mental task in different trials, the independent components of EEG are very similar. It means that the independent components can be used as the mental EEG patterns to classify the different mental tasks.
基金supported by the Italian Ministry for University,Scientific Research and Technologythe Italian Ministry of Health,the Fondazione Giuseppe e Mafalda Luce(Milan,Italy)+3 种基金Autism Aid ONLUS(Naples,Italy)the Autism Speaks Foundation(Princeton,NJ)the Autism Research Institute(San Diego,CA)the European Union(IMI project EU-AIMS)
文摘Autism is a complex neuropsychiatric disorder of developmental origin, where multiple genetic and environmental factors likely interact resulting in a clinical continuum between "affected" and "unaffected" individuals in the general population. During the last two decades, relevant progress has been made in identifying chromosomal regions and genes in linkage or association with autism, but no single gene has emerged as a major cause of disease in a large number of patients. The purpose of this paper is to discuss specific methodological issues and experimental strategies in autism genetic research, based on fourteen years of experience in patient recruitment and association studies of autism spectrum disorder in Italy.
