In order to restrict non-yielding maneuvers of left-turning vehicles,an optimal design of left-lane line extensions is proposed to solve the problem.A field observation was conducted to collect a data set of left-turn...In order to restrict non-yielding maneuvers of left-turning vehicles,an optimal design of left-lane line extensions is proposed to solve the problem.A field observation was conducted to collect a data set of left-turning vehicles at the beginning of a green phase at two similar intersections(one with a permitted phase and the other with a protected phase).The comparative analysis shows no significant difference in the speed distribution using either a permitted phase or a protected phase,but it reveals that a permitted phase can lead to a larger acceleration when the left-turn vehicles pass through the conflict points.Those indicate the existence of non-yielding maneuvers of left-turn vehicles at signalized intersections with a permitted phase.Optimal designed left-lane line extensions contain two types of segments,circular curves and transition curves,and they are only related to four geometry parameters of an intersection.The proposed method is easy to use and it can offer reference for intersection channelization and traffic organization.展开更多
To maximize the number of vehicles passing by the stop-line in a cycle and improve the operation efficiency of intersection in China, the settlement of left-turn lane waiting-zone is becoming prevailing. Based on conf...To maximize the number of vehicles passing by the stop-line in a cycle and improve the operation efficiency of intersection in China, the settlement of left-turn lane waiting-zone is becoming prevailing. Based on conflicting-point method, the internal mechanism of left-turn flow after stopping line was analyzed through taking postposition left-turn lane waiting-zone intersection for instance. The relationship between the first left-turn vehicle and the last vehicle of previous phase passing the conflicting point was expounded. According to the time of successive arriving of two vehicle flows at conflicting-point, the reasonable layout for waiting area of left-turn vehicles was researched when the clearance index was less than O. The results suggest that the appropriate layout for waiting area of left-turning vehicles can improve the operation efficiency of intersections.展开更多
In order to gain circularly polarized light of left-handed and right-handed rotation by using a fixed device, a left-handed and right-handed rotation double function circular polarizer is designed with two λ/4 retard...In order to gain circularly polarized light of left-handed and right-handed rotation by using a fixed device, a left-handed and right-handed rotation double function circular polarizer is designed with two λ/4 retarders and one polarizer, and its operating principle is analysed by matrix optical means. The result indicates that when the monochromatic light enters this circular polarizer in the positive direction and the negative direction,the emergent light should be circularly polarized light,of left-handed and right-handed rotation respectively. The testing system has been established to verify the above results.展开更多
Objective There is little population-based data on the prevalence and the environmental or genetic determinants of left ventricular hypertrophy (LVH) in China. The purpose of this paper is to study LVH in relation t...Objective There is little population-based data on the prevalence and the environmental or genetic determinants of left ventricular hypertrophy (LVH) in China. The purpose of this paper is to study LVH in relation to systolic blood pressure and the angiotensin converting enzyme (ACE) insertion/deletion(I/D) polymorphism in Chinese. Methods We recorded 12- lead ECG (CardioSoft, v4.2) in 1365 residents in the Jingning County, Zhejiang Province, China. LVH was defined according to the gender-specific Sokolow-Lyon and Cornell product ECG criteria. Results Regardless of whether the Sokolow-Lyon or Cornell product ECG criteria was used, the prevalence of LVH (20.7% and 4.8%, respectively) significantly (P〈0.0001) increased with male gender (odds ratio [OR] 2.33 and 7.15) and systolic blood pressure (per 10 mm Hg increase, OR 1.46 and 1.33). If the Sokolow-Lyon criteria was used, the prevalence of LVH was also influenced by alcohol intake (OR 1.44, P=-0.03) and body mass index (OR 0.83, P=0.0005). The association between the Sokolow-Lyon voltage amplitude and the ACE I/D polymorphism was dependent on antihypertensive therapy (P=0.01). In 1262 untreated subjects, but not 103 patients on antihypertensive medication, the ACE DD compared with II subjects had significantly higher Sokolow-Lyon voltage amplitudes (29.8:-0.6 vs. 28.0-3:0.5 mV, P=-0.02) and higher risk of LVH (OR 1.74, 95% CI: 1.12-2.69, P=-0.01). Conclusion LVH is prevalent in Chinese, and is associated with systolic blood pressure and the ACE D allele. The genetic association might be modulated by antihypertensive therapy(J Geriatr Cardio12009; 6:131-136).展开更多
The left-inverse system with minimal order and its algorithms of discrete-time nonlinear systems are studied in a linear algebraic framework. The general structure of left-inverse system is described and computed in s...The left-inverse system with minimal order and its algorithms of discrete-time nonlinear systems are studied in a linear algebraic framework. The general structure of left-inverse system is described and computed in symbolic algorithm. Two algorithms are given for constructing left-inverse systems with minimal order.展开更多
Sulfotransferases(SULTs) are one of the most important phase II drug-metabolizing enzymes. Among them, aryl sulfotransferases(SULT1A1) and estrogen sulfotransferase(EST, SULT1E1) belong to the rSULT1 family that...Sulfotransferases(SULTs) are one of the most important phase II drug-metabolizing enzymes. Among them, aryl sulfotransferases(SULT1A1) and estrogen sulfotransferase(EST, SULT1E1) belong to the rSULT1 family that catalyzes sulfation of phenolic compounds. Dopamine(DA) acts as a vital neurotransmitter in central nervous system(CNS) and regulates a variety of activities in periphery. In our study, we aim to detect the effects of exogenous DA and levodopa(L-DOPA) on rSULTs(rSULT1A1 and rSULT1E1) in rat liver. In order to achieve this target, varying doses of DA(0, 2, 10 and 100 mg/kg/d) and L-DOPA(0, 5, 25 and 125 mg/kg/d) were provided to male and female rats, respectively. Real-time PCR assay and western blot were used in the determination of the mRNA and protein expression of rSULTs. PNPS assay and radioactivity assay were applied to the detection of enzyme activity of rSULT1A1 and rSULT1E1, respectively. Our results showed that DA induced the expression and activity of rSULT1A1 in the liver of male and female rats and DA had little effect on rSULT1E1. However, L-DOPA caused no evident change of rSULT1A1 in both sex and had no significant effect on rSULT1E1 in female rat liver, but increased rSULT1E1 expression and activity only in male rat liver when administered at high dose. Our results suggest that DA plays different roles in the regulation of rSULT1A1 and rSULT1E1 when it is in periphery or in the CNS.展开更多
基金The National Natural Science Foundation of China(No.51278220)
文摘In order to restrict non-yielding maneuvers of left-turning vehicles,an optimal design of left-lane line extensions is proposed to solve the problem.A field observation was conducted to collect a data set of left-turning vehicles at the beginning of a green phase at two similar intersections(one with a permitted phase and the other with a protected phase).The comparative analysis shows no significant difference in the speed distribution using either a permitted phase or a protected phase,but it reveals that a permitted phase can lead to a larger acceleration when the left-turn vehicles pass through the conflict points.Those indicate the existence of non-yielding maneuvers of left-turn vehicles at signalized intersections with a permitted phase.Optimal designed left-lane line extensions contain two types of segments,circular curves and transition curves,and they are only related to four geometry parameters of an intersection.The proposed method is easy to use and it can offer reference for intersection channelization and traffic organization.
基金Sponsored by the National Natural Science Foundation of China(Grant No.70631002)Youth Science &Technology Foundation of Xi’an University of Architecture &Technology(Grant No.0608)
文摘To maximize the number of vehicles passing by the stop-line in a cycle and improve the operation efficiency of intersection in China, the settlement of left-turn lane waiting-zone is becoming prevailing. Based on conflicting-point method, the internal mechanism of left-turn flow after stopping line was analyzed through taking postposition left-turn lane waiting-zone intersection for instance. The relationship between the first left-turn vehicle and the last vehicle of previous phase passing the conflicting point was expounded. According to the time of successive arriving of two vehicle flows at conflicting-point, the reasonable layout for waiting area of left-turn vehicles was researched when the clearance index was less than O. The results suggest that the appropriate layout for waiting area of left-turning vehicles can improve the operation efficiency of intersections.
文摘In order to gain circularly polarized light of left-handed and right-handed rotation by using a fixed device, a left-handed and right-handed rotation double function circular polarizer is designed with two λ/4 retarders and one polarizer, and its operating principle is analysed by matrix optical means. The result indicates that when the monochromatic light enters this circular polarizer in the positive direction and the negative direction,the emergent light should be circularly polarized light,of left-handed and right-handed rotation respectively. The testing system has been established to verify the above results.
基金The authors gratefully acknowledge the voluntary collaboration of the study participants and the support of the local public health authorities of Jingning County, Zhejiang Province, China. This study was financially supported by grants from the National Natural Science Foundation of China (grants 30871360 and 30871081), Beij'ing, China, and the Shanghai Commissions of Science and Technology (grant 07JC14047 and the "Rising Star" program 06QA14043) and Education (grant 07ZZ32 and the "Dawn" program 08SG20), and the European Union (InGenious HyperCare LSHM-CT-2006-037093 and HYPERGENES FP7-HEALTH-2007-201550). Dr Alexander Headley was supported by the AusAID Australian Youth Ambassadors for Development scheme and the George Foundation of the George Institute for International Health, Sydney, Australia.
文摘Objective There is little population-based data on the prevalence and the environmental or genetic determinants of left ventricular hypertrophy (LVH) in China. The purpose of this paper is to study LVH in relation to systolic blood pressure and the angiotensin converting enzyme (ACE) insertion/deletion(I/D) polymorphism in Chinese. Methods We recorded 12- lead ECG (CardioSoft, v4.2) in 1365 residents in the Jingning County, Zhejiang Province, China. LVH was defined according to the gender-specific Sokolow-Lyon and Cornell product ECG criteria. Results Regardless of whether the Sokolow-Lyon or Cornell product ECG criteria was used, the prevalence of LVH (20.7% and 4.8%, respectively) significantly (P〈0.0001) increased with male gender (odds ratio [OR] 2.33 and 7.15) and systolic blood pressure (per 10 mm Hg increase, OR 1.46 and 1.33). If the Sokolow-Lyon criteria was used, the prevalence of LVH was also influenced by alcohol intake (OR 1.44, P=-0.03) and body mass index (OR 0.83, P=0.0005). The association between the Sokolow-Lyon voltage amplitude and the ACE I/D polymorphism was dependent on antihypertensive therapy (P=0.01). In 1262 untreated subjects, but not 103 patients on antihypertensive medication, the ACE DD compared with II subjects had significantly higher Sokolow-Lyon voltage amplitudes (29.8:-0.6 vs. 28.0-3:0.5 mV, P=-0.02) and higher risk of LVH (OR 1.74, 95% CI: 1.12-2.69, P=-0.01). Conclusion LVH is prevalent in Chinese, and is associated with systolic blood pressure and the ACE D allele. The genetic association might be modulated by antihypertensive therapy(J Geriatr Cardio12009; 6:131-136).
文摘The left-inverse system with minimal order and its algorithms of discrete-time nonlinear systems are studied in a linear algebraic framework. The general structure of left-inverse system is described and computed in symbolic algorithm. Two algorithms are given for constructing left-inverse systems with minimal order.
基金National Natural Science Foundation of China(Grant No.81072699)
文摘Sulfotransferases(SULTs) are one of the most important phase II drug-metabolizing enzymes. Among them, aryl sulfotransferases(SULT1A1) and estrogen sulfotransferase(EST, SULT1E1) belong to the rSULT1 family that catalyzes sulfation of phenolic compounds. Dopamine(DA) acts as a vital neurotransmitter in central nervous system(CNS) and regulates a variety of activities in periphery. In our study, we aim to detect the effects of exogenous DA and levodopa(L-DOPA) on rSULTs(rSULT1A1 and rSULT1E1) in rat liver. In order to achieve this target, varying doses of DA(0, 2, 10 and 100 mg/kg/d) and L-DOPA(0, 5, 25 and 125 mg/kg/d) were provided to male and female rats, respectively. Real-time PCR assay and western blot were used in the determination of the mRNA and protein expression of rSULTs. PNPS assay and radioactivity assay were applied to the detection of enzyme activity of rSULT1A1 and rSULT1E1, respectively. Our results showed that DA induced the expression and activity of rSULT1A1 in the liver of male and female rats and DA had little effect on rSULT1E1. However, L-DOPA caused no evident change of rSULT1A1 in both sex and had no significant effect on rSULT1E1 in female rat liver, but increased rSULT1E1 expression and activity only in male rat liver when administered at high dose. Our results suggest that DA plays different roles in the regulation of rSULT1A1 and rSULT1E1 when it is in periphery or in the CNS.