Objective:Osteosarcoma is a highly aggressive primary malignant bone tumor commonly seen in children and adolescents,with a poor prognosis.Anchorage-dependent cell death(anoikis)has been proven to be indispensable in ...Objective:Osteosarcoma is a highly aggressive primary malignant bone tumor commonly seen in children and adolescents,with a poor prognosis.Anchorage-dependent cell death(anoikis)has been proven to be indispensable in tumor metastasis,regulating the migration and adhesion of tumor cells at the primary site.However,as a type of programmed cell death,anoikis is rarely studied in osteosarcoma,especially in the tumor immune microenvironment.This study aims to clarify prognostic value of anoikis and tumor immune microenvironment-related gene in the treatment of osteosarcoma.Methods:Anoikis-related genes(ANRGs)were obtained from GeneCards.Clinical information and ANRGs expression profiles of osteosarcoma patients were sourced from the therapeutically applicable research to generate effective therapies and Gene Expression Omnibus(GEO)databases.ANRGs highly associated with tumor immune microenvironment were identified by the estimate package and the weighted gene coexpression network analysis(WGCNA)algorithm.Machine learning algorithms were performed to construct long-term survival predictive strategy,each sample was divided into high-risk and low-risk subgroups,which was further verified in the GEO cohort.Finally,based on single-cell RNA-seq from the GEO database,analysis was done on the function of signature genes in the osteosarcoma tumor microenvironment.Results:A total of 51 hub ANRGs closely associated with the tumor microenvironment were identified,from which 3 genes(MERTK,BNIP3,S100A8)were selected to construct the prognostic model.Significant differences in immune cell activation and immune-related signaling pathways were observed between the high-risk and low-risk groups based on tumor microenvironment analysis(all P<0.05).Additionally,characteristic genes within the osteosarcoma microenvironment were identified in regulation of intercellular crosstalk through the GAS6-MERTK signaling pathway.Conclusion:The prognostic model based on ANRGs and tumor microenvironment demonstrate good predictive power and provide more personalized treatment options for patients with osteosarcoma.展开更多
To investigate drivers' lane-changing behavior under different information feedback strategies,a microscopic traffic simulation based on the cellular automaton model was made on the typical freeway with a regular ...To investigate drivers' lane-changing behavior under different information feedback strategies,a microscopic traffic simulation based on the cellular automaton model was made on the typical freeway with a regular lane and a high-occupancy one. A new dynamic tolling scheme in terms of the real-time traffic condition on the high-occupancy lane was further designed to enhance the whole freeway's flow throughput. The results show that the mean velocity feedback strategy is generally more efficient than the travel time feedback strategy in correctly guiding drivers' lane choice behavior. Specifically,the toll level,lane-changing rate and freeway's throughput and congestion coefficient induced by the travel time feedback strategy oscillate with larger amplitude and longer period. In addition,the dynamic tolling scheme can make the high-occupancy lane less congested and maximize the freeway's throughput when the regular-lane inflow rate is larger than 0.45.展开更多
Mechanical vibration of target structures will modulate the phase function of radar backscattering,and will induce the frequency modulation of returned signals from the target. It generates a side bands of the target ...Mechanical vibration of target structures will modulate the phase function of radar backscattering,and will induce the frequency modulation of returned signals from the target. It generates a side bands of the target body Doppler frequency shift,which is helpful for target recognition. Based on this,a micro-Doppler atomic storehouse is built for the target recognition,and four kinds of common classifiers are used separately to perform the classified recognition. The simulation experimental results show that this method has high recognition rate above 90%.展开更多
Medical image registration is important in many medical applications. Registration method based on maximization of mutual information of voxel intensities is one of the most popular methods for 3-D multi-modality medi...Medical image registration is important in many medical applications. Registration method based on maximization of mutual information of voxel intensities is one of the most popular methods for 3-D multi-modality medical image registration. Generally, the optimization process is easily trapped in local maximum, resulting in wrong registration results. In order to find the correct optimum, a new multi-resolution approach for brain image registration based on normalized mutual information is proposed. In this method, to eliminate the effect of local optima, multi-scale wavelet transformation is adopted to extract the image edge features. Then the feature images are registered, and the result at this level is taken as the initial estimate for the registration of the original images. Three-dimensional volumes are used to test the algorithm. Experimental results show that the registration strategy proposed is a robust and efficient method which can reach sub-voxel accuracy and improve the optimization speed.展开更多
The paper addresses the controversial question of the role of clay-sized dust in the formation of paleosols in coastal eolianites, Israel. At the Habonim type section, the pedocomplex dated by archaeology and luminesc...The paper addresses the controversial question of the role of clay-sized dust in the formation of paleosols in coastal eolianites, Israel. At the Habonim type section, the pedocomplex dated by archaeology and luminescence to 45-135 ka ago shows at least three paleosols, not separated by non-soil sediments. The oldest reddish paleosol (apparently related to MIS 5) is magnetically enhanced, leached from carbonates, with signs of bioturbation and strongly aged clay coatings. The reddening is due to very fine, -20 nm, poorly crystallized, superparamagnetic (SP) hematite, as determined by Mossbauer studies. In subsoil, lithorelics of eolianite are found. Over time, the soil surface aggraded due to accelerated fine dust accumulation alongside local slope wash. On younger materials formed magnetically depleted vertisols, dominated by smectite-type expandable paramagnetic clays. In thin sections, vertisols exhibit strong stipple-speckled and striated b-fabric due to shrink-swell processes, impregnative calcite nodules and Fe-Mn redistribution. The uppermost hydric vertisol shows the strongest expression of juxtaposed features of recurrent calcite and Fe precipitation. This paleosol developed on colluvial soil materials, as evidenced by mixing of clay coated and uncoated grains of quartz and calcite allochems. M6ssbauer spectra show high amounts of Fe(III) incorporated in the clay structure, low amounts of SP goethite and absence of SP hematite. Whilst magnetic susceptibility drops in vertisols to minimal values, increase. The latter along ferrimagnetie grain sizes with differences in the hierarchy of microfabric features is taken as indication for lithologic discontinuities which may have resulted from continuous, albeit variable and low-intensity, input of eolian clay from both remote Saharan and local sources, roughly dated to the earlier to middle part of the Last Glacial.展开更多
Wireless power transmission based on inductive coupling for remotely implanted micro devices has been considered in this paper. The receiving coil, integrated in microsystems and the external transmitting coil compose...Wireless power transmission based on inductive coupling for remotely implanted micro devices has been considered in this paper. The receiving coil, integrated in microsystems and the external transmitting coil compose a loosely coupled transformer. The coupling coefficient was calculated and measured on spacing misalignments. The geometric size of transmitting coil was analyzed for the target of remotely delivering power. The received power was maximized by choosing appropriate value of frequency, tuning capacitance and the load resistance. A conventional full bridge rectifier circuit was employed to convert ac to dc voltage. The received dc power was up to 160 mW with a transmitting vohage of 5 Vrms when the receiving coil was placed at the center of the transmitting coil. This may meet the requirement of some microsystems for high power over a long time.展开更多
We study the entanglement of the superconducting charge qubit with the quantized electromagnetic field in a microwave cavity. It can be controlled dynamically by a classical external field threading the SQUID within t...We study the entanglement of the superconducting charge qubit with the quantized electromagnetic field in a microwave cavity. It can be controlled dynamically by a classical external field threading the SQUID within the charge qubit. Utilizing the controllable quantum entanglement, we can demonstrate the dynamic process of the quantum storage of information carried by charge qubit. On the other hand, based on this engineered quantum entanglement, we can also demonstrate a progressive decoherence of charge cubit with quantum jump due to the coupling with the cavity field in quasi-classical state.展开更多
Previously, the military establishment has been the primary developer and user of micro technologies associated with unmanned systems. As these technologies become available commercially, a need exists to integrate th...Previously, the military establishment has been the primary developer and user of micro technologies associated with unmanned systems. As these technologies become available commercially, a need exists to integrate the use of the technology into local or regional public safety and homeland security incidents. The purpose of this presentation is to explain several key factors to consider when using micro technologies and unmanned systems in support of public safety and homeland security officials. Real time information is critical to the decision making process for public safety and homeland security officials to make assessments and quickly resolve crisis situations. Unmanned micro-vehicles and micro technologies are well suited to remotely observe, gather essential information, and immediately relay it to incident responders. These technologies can provide extremely important support during responses to hostage situations, hazardous environments, search and rescue, natural disasters, border patrol and many others. The true benefit is having remote resources providing real time support to incident responders. This paper discusses the use of several different types of micro-vehicle platforms in public safety scenarios and their use of associated technologies such as GPS (Global Positioning System) autopilot, communication, and sensor devices.展开更多
Fermentative production of chlortetracycline is a complex fed-batch bioprocess. It generally takes over 90 h for cultivation and is often contaminated by undesired microorganisms. Once the fermentation system is conta...Fermentative production of chlortetracycline is a complex fed-batch bioprocess. It generally takes over 90 h for cultivation and is often contaminated by undesired microorganisms. Once the fermentation system is contaminated to certain extent, the product quality and yield will be seriously affected, leading to a substantial economic loss. Using information fusion based on the Dezer–Smarandache theory, self-recursive wavelet neural network and unscented kalman filter, a novel method for online prediction of contamination is developed. All state variables of culture process involving easy-to-measure and difficult-to-measure variables commonly obtained with soft-sensors present their contamination symptoms. By extracting and fusing latent information from the changing trend of each variable, integral and accurate prediction results for contamination can be achieved. This makes preventive and corrective measures be taken promptly. The field experimental results show that the method can be used to detect the contamination in time, reducing production loss and enhancing economic efficiency.展开更多
The phase information of an enlarged source is reconstructed with an annular two-zone phase-only filter in a fluorescent confocal scanning optical microscope for resolution improvement. The dependences of its resoluti...The phase information of an enlarged source is reconstructed with an annular two-zone phase-only filter in a fluorescent confocal scanning optical microscope for resolution improvement. The dependences of its resolution on the source size and on the phase transmission of the outer annular zone of the falter are investigated theoretically by use of its three-dimensional optical transfer function (3D OTF ). The increased source size and the required phase value of the outer annular zone of the phase-only falter for an optimal 3D OTF of the optical system are presented.展开更多
The aim of this study is to report the use of RE (remote experimentation) in an educational press. The authors developed this remote experiment with the objective to study the Hooke's law through the analysis of th...The aim of this study is to report the use of RE (remote experimentation) in an educational press. The authors developed this remote experiment with the objective to study the Hooke's law through the analysis of the coil spring. The remote experiment is available in a website, where the students can manipulate and observe the educational press and confirm Hooke's statements with the output information. In addition, the students will have the opportunity to read in the website about the educational press, the physical law, and the use of the press in industrial processes. This remote experimentation exerts a force in the mechanical spring creating a deformation. In the defined point, the microcomputer will collect the data from the sensors, and it will save this data in the database. After the process execution, a graph with the data will be plotted in the website. The tests confirm that the educational press has informational potential because it returned values consistent with Hooke's law and the experiment presented repetition in all tests realized.展开更多
The phenotypic traits of high prolificacy, low fat on the rib eye muscle and high tolerance to internal parasites make the Barbados Blackbelly (BBB) sheep a valuable economic resource for small subsistence farmers o...The phenotypic traits of high prolificacy, low fat on the rib eye muscle and high tolerance to internal parasites make the Barbados Blackbelly (BBB) sheep a valuable economic resource for small subsistence farmers on some Caribbean islands. However, the determination of what is a purebred BBB sheep has long been a contentious issue because of the subjectivity. It is therefore necessary to have a more reliable means of identifying what is a purebred BBB sheep for purposes of conservation and breed improvement. Three geographically isolated populations of BBB sheep were genetically analysed at 19 microsatellite loci. Eighteen of the microsatellites were found to be useful for genetic analysis of the BBB sheep, based on polymorphic information content (PIC) values (0.5 〈 PIC 〉 0.25). One microsatellite was not useful for genetic analysis based on PIC (0.111), however it is considered to be a locus of interest because it is fully inbred (f = 1) and homozygous in all of the populations analysed. The analysis also showed that the purebred population of BBB sheep can be distinguished from other populations by formation of distinct clusters when subjected to analysis of molecular variance (AMOVA) and the construction of a rooted consensus tree using the Neighbour-Joining method and pair-wise distances based on marker estimated kinships.展开更多
The use of social media in political communication has demonstrated its significance by the example of Arab Spring and the 2008 US presidential election, but its role in non-western democratic countries like Taiwan ha...The use of social media in political communication has demonstrated its significance by the example of Arab Spring and the 2008 US presidential election, but its role in non-western democratic countries like Taiwan has rarely been examined. Micro-blogs share some characteristics with other types of social media but operate in a lighter way that has made it more and more popular among Internet users. Most researchers focus on the better-known Twitter, however, Plurk has found a niche and becomes the leading type of micro-blog in Taiwan and many politicians enjoy using it for political communication. This study seeks to answer the question "What patterns do Taiwan Residents politicians exhibit when utilizing Plurk?". By combining Habermasian communicative action theory and Foot and Schneider's Web Sphere, this research attempts to form a theoretical framework for micro-blogs. In-depth interviews were conducted with Taiwan Residents politicians at various levels and it was discovered that the broad pattern of political communication via Plurk may be characterised in Habermasian terms as strategic, through information broadcasting, public opinion formation, and political mobilization. In addition, this research shows that Taiwan Residents politicians use Plurk to gather information and ideas in exchanges which have dialogic elements.展开更多
In this paper, a theoretical scheme is proposed to implement the Deutsch-Jozsa algorithm with SQUIDs (superconducting quantum-interference devices) in cavity via Raman transition. The scheme only requires a quantize...In this paper, a theoretical scheme is proposed to implement the Deutsch-Jozsa algorithm with SQUIDs (superconducting quantum-interference devices) in cavity via Raman transition. The scheme only requires a quantized cavity field and classical microwave pulses. In this scheme, no transfer of quantum information between the SQUIDs and the cavity is required, the cavity field is only virtually excited and thus the cavity decay is suppressed.展开更多
The relationship between microsatellite polymorphism and body weight of captive bred Chinese sea cucumber Apostichopus japonicus was investigated in two local populations in Dalian. Among ten loci discovered, nine sho...The relationship between microsatellite polymorphism and body weight of captive bred Chinese sea cucumber Apostichopus japonicus was investigated in two local populations in Dalian. Among ten loci discovered, nine show changes except for AJ07 loci. Seven loci were found highly polymorphic in both populations. For each locus in two populations, the average number of alleles is 6.428 6 and 6.285 7, the average observed heterozygosity at 0.225 7 and 0.245 9, the expected heterozygosity at 0.776 8 and 0.748 8, the polymorphism information content (PIC) at 0.709 2 and 0.674 6, respectively. Further analysis show significant correlation between A. japonicus body weight and occurrence markers AJ02 and AJ04. The findings of the relation may be helpful for molecular breeding, as well as the marker-assisted selection of sea cucumbers.展开更多
Many problems in applied mathematics lead to ordinary differential equation. In this paper, a considerable refinement and improvement of the Euler's method obtained using PSO (particle swarm optimization) was prese...Many problems in applied mathematics lead to ordinary differential equation. In this paper, a considerable refinement and improvement of the Euler's method obtained using PSO (particle swarm optimization) was presented. PSO is a technique based on the cooperation between particles. The exchange of information between these particles allows to resolve difficult problems. This approach is carefully handled and tested with an illustrated example.展开更多
Data are critically important to good decision-making. In an increasingly complex economy, conventional data collecting schemes are no longer sufficient. To deal with the challenge of maintaining its statistics releva...Data are critically important to good decision-making. In an increasingly complex economy, conventional data collecting schemes are no longer sufficient. To deal with the challenge of maintaining its statistics relevant to the users in an ever-shifting environment, the Banco de Portugal decided to explore the largely unused statistical potential of the available micro-databases and to integrate the existing administrative and survey data, thus enhancing the basic information infrastructure while protecting confidentiality. This presentation will address the benefits and problems to be dealt with when two or more data-sources are to be integrated.展开更多
基金This work was supported by the National Natural Science Foundation(82172594 and 82373046)the Hunan Graduate Research Innovation Project(CX20230318),China.
文摘Objective:Osteosarcoma is a highly aggressive primary malignant bone tumor commonly seen in children and adolescents,with a poor prognosis.Anchorage-dependent cell death(anoikis)has been proven to be indispensable in tumor metastasis,regulating the migration and adhesion of tumor cells at the primary site.However,as a type of programmed cell death,anoikis is rarely studied in osteosarcoma,especially in the tumor immune microenvironment.This study aims to clarify prognostic value of anoikis and tumor immune microenvironment-related gene in the treatment of osteosarcoma.Methods:Anoikis-related genes(ANRGs)were obtained from GeneCards.Clinical information and ANRGs expression profiles of osteosarcoma patients were sourced from the therapeutically applicable research to generate effective therapies and Gene Expression Omnibus(GEO)databases.ANRGs highly associated with tumor immune microenvironment were identified by the estimate package and the weighted gene coexpression network analysis(WGCNA)algorithm.Machine learning algorithms were performed to construct long-term survival predictive strategy,each sample was divided into high-risk and low-risk subgroups,which was further verified in the GEO cohort.Finally,based on single-cell RNA-seq from the GEO database,analysis was done on the function of signature genes in the osteosarcoma tumor microenvironment.Results:A total of 51 hub ANRGs closely associated with the tumor microenvironment were identified,from which 3 genes(MERTK,BNIP3,S100A8)were selected to construct the prognostic model.Significant differences in immune cell activation and immune-related signaling pathways were observed between the high-risk and low-risk groups based on tumor microenvironment analysis(all P<0.05).Additionally,characteristic genes within the osteosarcoma microenvironment were identified in regulation of intercellular crosstalk through the GAS6-MERTK signaling pathway.Conclusion:The prognostic model based on ANRGs and tumor microenvironment demonstrate good predictive power and provide more personalized treatment options for patients with osteosarcoma.
基金Project(70521001) supported by the National Natural Science Foundation of ChinaProject(2006CB705503) supported by the National Basic Research Program of ChinaProject supported by the Innovation Foundation of BUAA for PhD Graduates
文摘To investigate drivers' lane-changing behavior under different information feedback strategies,a microscopic traffic simulation based on the cellular automaton model was made on the typical freeway with a regular lane and a high-occupancy one. A new dynamic tolling scheme in terms of the real-time traffic condition on the high-occupancy lane was further designed to enhance the whole freeway's flow throughput. The results show that the mean velocity feedback strategy is generally more efficient than the travel time feedback strategy in correctly guiding drivers' lane choice behavior. Specifically,the toll level,lane-changing rate and freeway's throughput and congestion coefficient induced by the travel time feedback strategy oscillate with larger amplitude and longer period. In addition,the dynamic tolling scheme can make the high-occupancy lane less congested and maximize the freeway's throughput when the regular-lane inflow rate is larger than 0.45.
基金the foundation of doctor academic degree from Education Minirstry of China (20060699024)
文摘Mechanical vibration of target structures will modulate the phase function of radar backscattering,and will induce the frequency modulation of returned signals from the target. It generates a side bands of the target body Doppler frequency shift,which is helpful for target recognition. Based on this,a micro-Doppler atomic storehouse is built for the target recognition,and four kinds of common classifiers are used separately to perform the classified recognition. The simulation experimental results show that this method has high recognition rate above 90%.
基金Supported by National Natural Science Foundation of China (No.60373061)Natural Science Foundation of Tianjin (No.04310491R)+1 种基金National Natural Science Foundation of ChinaGeneral Administration of Civil Aviation of China (No.60372048) .
文摘Medical image registration is important in many medical applications. Registration method based on maximization of mutual information of voxel intensities is one of the most popular methods for 3-D multi-modality medical image registration. Generally, the optimization process is easily trapped in local maximum, resulting in wrong registration results. In order to find the correct optimum, a new multi-resolution approach for brain image registration based on normalized mutual information is proposed. In this method, to eliminate the effect of local optima, multi-scale wavelet transformation is adopted to extract the image edge features. Then the feature images are registered, and the result at this level is taken as the initial estimate for the registration of the original images. Three-dimensional volumes are used to test the algorithm. Experimental results show that the registration strategy proposed is a robust and efficient method which can reach sub-voxel accuracy and improve the optimization speed.
基金supported by the Research Authority of the University of Haifa, and the Joint Foundation between Technion and University of Haifa
文摘The paper addresses the controversial question of the role of clay-sized dust in the formation of paleosols in coastal eolianites, Israel. At the Habonim type section, the pedocomplex dated by archaeology and luminescence to 45-135 ka ago shows at least three paleosols, not separated by non-soil sediments. The oldest reddish paleosol (apparently related to MIS 5) is magnetically enhanced, leached from carbonates, with signs of bioturbation and strongly aged clay coatings. The reddening is due to very fine, -20 nm, poorly crystallized, superparamagnetic (SP) hematite, as determined by Mossbauer studies. In subsoil, lithorelics of eolianite are found. Over time, the soil surface aggraded due to accelerated fine dust accumulation alongside local slope wash. On younger materials formed magnetically depleted vertisols, dominated by smectite-type expandable paramagnetic clays. In thin sections, vertisols exhibit strong stipple-speckled and striated b-fabric due to shrink-swell processes, impregnative calcite nodules and Fe-Mn redistribution. The uppermost hydric vertisol shows the strongest expression of juxtaposed features of recurrent calcite and Fe precipitation. This paleosol developed on colluvial soil materials, as evidenced by mixing of clay coated and uncoated grains of quartz and calcite allochems. M6ssbauer spectra show high amounts of Fe(III) incorporated in the clay structure, low amounts of SP goethite and absence of SP hematite. Whilst magnetic susceptibility drops in vertisols to minimal values, increase. The latter along ferrimagnetie grain sizes with differences in the hierarchy of microfabric features is taken as indication for lithologic discontinuities which may have resulted from continuous, albeit variable and low-intensity, input of eolian clay from both remote Saharan and local sources, roughly dated to the earlier to middle part of the Last Glacial.
基金National High Technology Research and Development Program of China(863 Program),Grant number:2004AA404013.
文摘Wireless power transmission based on inductive coupling for remotely implanted micro devices has been considered in this paper. The receiving coil, integrated in microsystems and the external transmitting coil compose a loosely coupled transformer. The coupling coefficient was calculated and measured on spacing misalignments. The geometric size of transmitting coil was analyzed for the target of remotely delivering power. The received power was maximized by choosing appropriate value of frequency, tuning capacitance and the load resistance. A conventional full bridge rectifier circuit was employed to convert ac to dc voltage. The received dc power was up to 160 mW with a transmitting vohage of 5 Vrms when the receiving coil was placed at the center of the transmitting coil. This may meet the requirement of some microsystems for high power over a long time.
文摘We study the entanglement of the superconducting charge qubit with the quantized electromagnetic field in a microwave cavity. It can be controlled dynamically by a classical external field threading the SQUID within the charge qubit. Utilizing the controllable quantum entanglement, we can demonstrate the dynamic process of the quantum storage of information carried by charge qubit. On the other hand, based on this engineered quantum entanglement, we can also demonstrate a progressive decoherence of charge cubit with quantum jump due to the coupling with the cavity field in quasi-classical state.
文摘Previously, the military establishment has been the primary developer and user of micro technologies associated with unmanned systems. As these technologies become available commercially, a need exists to integrate the use of the technology into local or regional public safety and homeland security incidents. The purpose of this presentation is to explain several key factors to consider when using micro technologies and unmanned systems in support of public safety and homeland security officials. Real time information is critical to the decision making process for public safety and homeland security officials to make assessments and quickly resolve crisis situations. Unmanned micro-vehicles and micro technologies are well suited to remotely observe, gather essential information, and immediately relay it to incident responders. These technologies can provide extremely important support during responses to hostage situations, hazardous environments, search and rescue, natural disasters, border patrol and many others. The true benefit is having remote resources providing real time support to incident responders. This paper discusses the use of several different types of micro-vehicle platforms in public safety scenarios and their use of associated technologies such as GPS (Global Positioning System) autopilot, communication, and sensor devices.
文摘Fermentative production of chlortetracycline is a complex fed-batch bioprocess. It generally takes over 90 h for cultivation and is often contaminated by undesired microorganisms. Once the fermentation system is contaminated to certain extent, the product quality and yield will be seriously affected, leading to a substantial economic loss. Using information fusion based on the Dezer–Smarandache theory, self-recursive wavelet neural network and unscented kalman filter, a novel method for online prediction of contamination is developed. All state variables of culture process involving easy-to-measure and difficult-to-measure variables commonly obtained with soft-sensors present their contamination symptoms. By extracting and fusing latent information from the changing trend of each variable, integral and accurate prediction results for contamination can be achieved. This makes preventive and corrective measures be taken promptly. The field experimental results show that the method can be used to detect the contamination in time, reducing production loss and enhancing economic efficiency.
文摘The phase information of an enlarged source is reconstructed with an annular two-zone phase-only filter in a fluorescent confocal scanning optical microscope for resolution improvement. The dependences of its resolution on the source size and on the phase transmission of the outer annular zone of the falter are investigated theoretically by use of its three-dimensional optical transfer function (3D OTF ). The increased source size and the required phase value of the outer annular zone of the phase-only falter for an optimal 3D OTF of the optical system are presented.
文摘The aim of this study is to report the use of RE (remote experimentation) in an educational press. The authors developed this remote experiment with the objective to study the Hooke's law through the analysis of the coil spring. The remote experiment is available in a website, where the students can manipulate and observe the educational press and confirm Hooke's statements with the output information. In addition, the students will have the opportunity to read in the website about the educational press, the physical law, and the use of the press in industrial processes. This remote experimentation exerts a force in the mechanical spring creating a deformation. In the defined point, the microcomputer will collect the data from the sensors, and it will save this data in the database. After the process execution, a graph with the data will be plotted in the website. The tests confirm that the educational press has informational potential because it returned values consistent with Hooke's law and the experiment presented repetition in all tests realized.
文摘The phenotypic traits of high prolificacy, low fat on the rib eye muscle and high tolerance to internal parasites make the Barbados Blackbelly (BBB) sheep a valuable economic resource for small subsistence farmers on some Caribbean islands. However, the determination of what is a purebred BBB sheep has long been a contentious issue because of the subjectivity. It is therefore necessary to have a more reliable means of identifying what is a purebred BBB sheep for purposes of conservation and breed improvement. Three geographically isolated populations of BBB sheep were genetically analysed at 19 microsatellite loci. Eighteen of the microsatellites were found to be useful for genetic analysis of the BBB sheep, based on polymorphic information content (PIC) values (0.5 〈 PIC 〉 0.25). One microsatellite was not useful for genetic analysis based on PIC (0.111), however it is considered to be a locus of interest because it is fully inbred (f = 1) and homozygous in all of the populations analysed. The analysis also showed that the purebred population of BBB sheep can be distinguished from other populations by formation of distinct clusters when subjected to analysis of molecular variance (AMOVA) and the construction of a rooted consensus tree using the Neighbour-Joining method and pair-wise distances based on marker estimated kinships.
文摘The use of social media in political communication has demonstrated its significance by the example of Arab Spring and the 2008 US presidential election, but its role in non-western democratic countries like Taiwan has rarely been examined. Micro-blogs share some characteristics with other types of social media but operate in a lighter way that has made it more and more popular among Internet users. Most researchers focus on the better-known Twitter, however, Plurk has found a niche and becomes the leading type of micro-blog in Taiwan and many politicians enjoy using it for political communication. This study seeks to answer the question "What patterns do Taiwan Residents politicians exhibit when utilizing Plurk?". By combining Habermasian communicative action theory and Foot and Schneider's Web Sphere, this research attempts to form a theoretical framework for micro-blogs. In-depth interviews were conducted with Taiwan Residents politicians at various levels and it was discovered that the broad pattern of political communication via Plurk may be characterised in Habermasian terms as strategic, through information broadcasting, public opinion formation, and political mobilization. In addition, this research shows that Taiwan Residents politicians use Plurk to gather information and ideas in exchanges which have dialogic elements.
基金supported in part by Scientific Research Program of Hubei Provincial Department of Education under Grant No.D200634001Natural Science Foundation of Jiangxi Province under Grant No. 0612006
文摘In this paper, a theoretical scheme is proposed to implement the Deutsch-Jozsa algorithm with SQUIDs (superconducting quantum-interference devices) in cavity via Raman transition. The scheme only requires a quantized cavity field and classical microwave pulses. In this scheme, no transfer of quantum information between the SQUIDs and the cavity is required, the cavity field is only virtually excited and thus the cavity decay is suppressed.
基金Supported by the National High Technology Research and Development Program of China (863 Program, No. 2006AA10A411)the Natural Science Foundation of Liaoning Province (No.20072139)the Grant of Dalian Fisheries University, the Key Laboratory Foundation of the Educational Department of Liaoning Province (No.2009S024)
文摘The relationship between microsatellite polymorphism and body weight of captive bred Chinese sea cucumber Apostichopus japonicus was investigated in two local populations in Dalian. Among ten loci discovered, nine show changes except for AJ07 loci. Seven loci were found highly polymorphic in both populations. For each locus in two populations, the average number of alleles is 6.428 6 and 6.285 7, the average observed heterozygosity at 0.225 7 and 0.245 9, the expected heterozygosity at 0.776 8 and 0.748 8, the polymorphism information content (PIC) at 0.709 2 and 0.674 6, respectively. Further analysis show significant correlation between A. japonicus body weight and occurrence markers AJ02 and AJ04. The findings of the relation may be helpful for molecular breeding, as well as the marker-assisted selection of sea cucumbers.
文摘Many problems in applied mathematics lead to ordinary differential equation. In this paper, a considerable refinement and improvement of the Euler's method obtained using PSO (particle swarm optimization) was presented. PSO is a technique based on the cooperation between particles. The exchange of information between these particles allows to resolve difficult problems. This approach is carefully handled and tested with an illustrated example.
文摘Data are critically important to good decision-making. In an increasingly complex economy, conventional data collecting schemes are no longer sufficient. To deal with the challenge of maintaining its statistics relevant to the users in an ever-shifting environment, the Banco de Portugal decided to explore the largely unused statistical potential of the available micro-databases and to integrate the existing administrative and survey data, thus enhancing the basic information infrastructure while protecting confidentiality. This presentation will address the benefits and problems to be dealt with when two or more data-sources are to be integrated.