In central part of Iraq within the vicinity of Karbala-Najaf, two cliffs called "Tar Al-Say'ed" and "Tar Al-Najaf" form conspicuous geomorphological forms between the Mesopotamia Plain and the Western and Souther...In central part of Iraq within the vicinity of Karbala-Najaf, two cliffs called "Tar Al-Say'ed" and "Tar Al-Najaf" form conspicuous geomorphological forms between the Mesopotamia Plain and the Western and Southern Deserts. The top surface between the two cliffs (tars) is covered by alluvial fan sediments, laid down by A1-Khir Valley when merging in a large depression due to the drop in the gradient of the valley. Consequently, the depression was divided into two parts, to the left is called Al-Razzazah Depression, whereas to the right is called Bahir Al-Najaf. This affected the course of the River Euphrates. The deposition stopped due to an uplift movement which caused the elevation of the two cliffs which are covered by alluvial fan sediments. The two cliffs had and are still suffering from retreating, due to lateral erosion by wave actions in Al-Razzazah Depression. Springs located along a straight line, sag pond, deflected drainage, shutter ridges and pressure ridges can be noticed in the area. The age of both cliffs is estimated to be upper Late Pleistocene--early Holocene.展开更多
Morphotaxonomy and seasonal abundance of dinoflagellates of the genera Prorocentrum and Mesoporos (Prorocentrales) were studied from nutrient-rich waters, Karachi Harbor and the mouth of the Manora Channel, Pakistan...Morphotaxonomy and seasonal abundance of dinoflagellates of the genera Prorocentrum and Mesoporos (Prorocentrales) were studied from nutrient-rich waters, Karachi Harbor and the mouth of the Manora Channel, Pakistan during May 2002-July 2003. Using both light and scanning electron microscopy, 13 species of Prorocentrales were identified according to cell shape, size, ornamentation of thecal plates, and architecture of apical platelets, apical pore area, marginal pores, and intercalary bands. P. sigmoides, P. arcuatum, P. scutellum, P. donghaiense, P. balticum, P. minimum, P. emarginatum, P. lima, P. faustiae, and Mesoporos perforatus constitute new records for sindh coast of Pakistan. The most abundant species were P. minimum/P, balticum (4.5x103 cells/L), P. micans (1.1~103 cells/L), P. gracile/P, sigmoides (2.5 x 102 cells/L) and P. donghaiense (6.6 x 103 cells/L) at temperatures of 29-31 ~C and salinities of 35-40. Maximum abundance was observed in winter and lower abundance in summer. There was no significant change in the distribution of species between stations except for the benthic species which occurred close to Karachi Harbor waters. Significant positive correlations were observed between Prorocentrum spp. and temperature (R2=0.27) and negative correlations with salinity (R2=-0.32) except for P. minimum and P. emarginatum which has negative correlation with temperature (R2=-0.24) and positive with salinity (R2=0.08, 0.19). The finding of potential okadaic-acid producing species of benthic Prorocentrum call for monitoring for possible human health problems in this region.展开更多
V3 loop of HIV-1 envelop protein gp120 plays a pivotal role in the entry process of HIV-1 into target cells. R15K, the relatively conserved region of V3 loop, can be used in binding studies instead of recombinant gp12...V3 loop of HIV-1 envelop protein gp120 plays a pivotal role in the entry process of HIV-1 into target cells. R15K, the relatively conserved region of V3 loop, can be used in binding studies instead of recombinant gp120 molecule. Polyanionic compounds, such as carrageenan, possess antiviral activity through disrupting gp120-CD4 interaction, and chemical modifications have been performed to improve such activity. In this work, we, for the first time, analyzed the interactions between carrageenan or its degradation and R15K by affinity capillary electrophoresis (ACE). Our results revealed that depolymerized carrageenan rather than carrageenan could bind to R15K. The binding constant of depolymerized carrageenan was (2.94±0.57)× 10^6 mol/L. Our finding indicated that the depolymerized carrageenan could be R15K antagonist, and it might inhibit the infection of HIV-1 through the entry process.展开更多
Urban growth is a key indicator of economic development.At the same time,haphazard urban growth creates serious socioeconomic,environmental and urban land management problems.In this context,understanding the process ...Urban growth is a key indicator of economic development.At the same time,haphazard urban growth creates serious socioeconomic,environmental and urban land management problems.In this context,understanding the process of urban landscape change is important for guiding the sustainable growth of urban areas.This study analyzes the urban land changes during 1990–2018 in two metropolitan cities of Gandaki basin:Pokhara and Bharatpur.Landsat satellite images were analyzed using supervised classification methods.The results revealed that the built-up area has increased significantly by 300%in Pokhara and by nearly 500%in the Bharatpur during the past 28 years.Population growth,migration from surrounding areas due to urban facilities and the easy lifestyle in cities were found to be major determinants of urban growth within the study area.In addition,the changing urban definition and expansion of municipal boundaries are key factors for rapid urban growth.Both cities are likely to grow in the future as they are both located in areas that encompass the high levels of commercial activity and modern service facilities.The haphazard urban growth should be minimized through planning and policies for sustainable urban development.展开更多
文摘In central part of Iraq within the vicinity of Karbala-Najaf, two cliffs called "Tar Al-Say'ed" and "Tar Al-Najaf" form conspicuous geomorphological forms between the Mesopotamia Plain and the Western and Southern Deserts. The top surface between the two cliffs (tars) is covered by alluvial fan sediments, laid down by A1-Khir Valley when merging in a large depression due to the drop in the gradient of the valley. Consequently, the depression was divided into two parts, to the left is called Al-Razzazah Depression, whereas to the right is called Bahir Al-Najaf. This affected the course of the River Euphrates. The deposition stopped due to an uplift movement which caused the elevation of the two cliffs which are covered by alluvial fan sediments. The two cliffs had and are still suffering from retreating, due to lateral erosion by wave actions in Al-Razzazah Depression. Springs located along a straight line, sag pond, deflected drainage, shutter ridges and pressure ridges can be noticed in the area. The age of both cliffs is estimated to be upper Late Pleistocene--early Holocene.
基金Supported by Scholarship (IRSIP) of Higher Education Commission,Islamabad,Pakistan for Doctoral student Miss.Sonia Munir
文摘Morphotaxonomy and seasonal abundance of dinoflagellates of the genera Prorocentrum and Mesoporos (Prorocentrales) were studied from nutrient-rich waters, Karachi Harbor and the mouth of the Manora Channel, Pakistan during May 2002-July 2003. Using both light and scanning electron microscopy, 13 species of Prorocentrales were identified according to cell shape, size, ornamentation of thecal plates, and architecture of apical platelets, apical pore area, marginal pores, and intercalary bands. P. sigmoides, P. arcuatum, P. scutellum, P. donghaiense, P. balticum, P. minimum, P. emarginatum, P. lima, P. faustiae, and Mesoporos perforatus constitute new records for sindh coast of Pakistan. The most abundant species were P. minimum/P, balticum (4.5x103 cells/L), P. micans (1.1~103 cells/L), P. gracile/P, sigmoides (2.5 x 102 cells/L) and P. donghaiense (6.6 x 103 cells/L) at temperatures of 29-31 ~C and salinities of 35-40. Maximum abundance was observed in winter and lower abundance in summer. There was no significant change in the distribution of species between stations except for the benthic species which occurred close to Karachi Harbor waters. Significant positive correlations were observed between Prorocentrum spp. and temperature (R2=0.27) and negative correlations with salinity (R2=-0.32) except for P. minimum and P. emarginatum which has negative correlation with temperature (R2=-0.24) and positive with salinity (R2=0.08, 0.19). The finding of potential okadaic-acid producing species of benthic Prorocentrum call for monitoring for possible human health problems in this region.
基金National Natural Science Foundation(Grant No.81373372)Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20110001110021 and 20130001110059)
文摘V3 loop of HIV-1 envelop protein gp120 plays a pivotal role in the entry process of HIV-1 into target cells. R15K, the relatively conserved region of V3 loop, can be used in binding studies instead of recombinant gp120 molecule. Polyanionic compounds, such as carrageenan, possess antiviral activity through disrupting gp120-CD4 interaction, and chemical modifications have been performed to improve such activity. In this work, we, for the first time, analyzed the interactions between carrageenan or its degradation and R15K by affinity capillary electrophoresis (ACE). Our results revealed that depolymerized carrageenan rather than carrageenan could bind to R15K. The binding constant of depolymerized carrageenan was (2.94±0.57)× 10^6 mol/L. Our finding indicated that the depolymerized carrageenan could be R15K antagonist, and it might inhibit the infection of HIV-1 through the entry process.
基金The National Natural Science Foundation of China(41761144081)The Second Tibetan Plateau Scientific Expedition and Research(2019QZKK2203)+1 种基金The International Partnership Program of Chinese Academy of Sciences(131C11KYSB20160061)The Chinese Academy of Sciences-The World Academy of Sciences(CAS-TWAS)President’s Fellowship Program for Ph D Study
文摘Urban growth is a key indicator of economic development.At the same time,haphazard urban growth creates serious socioeconomic,environmental and urban land management problems.In this context,understanding the process of urban landscape change is important for guiding the sustainable growth of urban areas.This study analyzes the urban land changes during 1990–2018 in two metropolitan cities of Gandaki basin:Pokhara and Bharatpur.Landsat satellite images were analyzed using supervised classification methods.The results revealed that the built-up area has increased significantly by 300%in Pokhara and by nearly 500%in the Bharatpur during the past 28 years.Population growth,migration from surrounding areas due to urban facilities and the easy lifestyle in cities were found to be major determinants of urban growth within the study area.In addition,the changing urban definition and expansion of municipal boundaries are key factors for rapid urban growth.Both cities are likely to grow in the future as they are both located in areas that encompass the high levels of commercial activity and modern service facilities.The haphazard urban growth should be minimized through planning and policies for sustainable urban development.