新理念下 如何培养学生的“新”能力

随着教育事业的发展和新型人才的培养需要,数学教学理念也发生了变化。为了适应新课程理念,小学数学的教学目标和教学要求也发生了变更,目的在于培养学生新的能力,去适应社会进步的需求。那么,如何在新理念下培养学生的“新”能力,就成为了亟待解决的问题。

On the method and mode of modern foreign language course design

This article is based on the theory of foreign language course design. It mainly introduces and analyzes the methods and mode of foreign language design and also integrates with the practice of foreign language teaching, the author thinks a competent foreign language teacher should not only be satisfied with inculcating ready-made knowledge, but they should also constantly foster the ability of blazing new trails and try to grasp the theory and methods of course design ,and try to carry out course design according to practice and try to give play to their teaching personality and creativity and to have a bold try and exploration and try to improve the foreign language course and foreign language teaching.

Constructivism-based Course Books＇ Compiling and a New Mode of Teaching

The paper explores the positive impact of constructivism-based course books compiling and the new mode of teaching, analyzes their effects on helping students improve their integrated English language competence, and pointing out that the development of teaching non-English major graduate students has raised new demands for teaching devices, teaching methodology and new roles of teachers and learners. Therefore, New Century Graduate English Series, as constructivism-based course books, has made some beneficial attempts for the implementation of the new graduate English teaching reauirements.

On the enlightenment of metaphor to English teaching

In cognitive linguistics, metaphor acts as an important tool in cognition. This paper explores and exposes the value of metaphor in English teaching. Thus, metaphor, as a significant way of thinking, not only provides the new way for English teaching, but also proposes the viewpoint that language teaching is one of the fields for cultivating thinking ability and creativity.

Urban Hierarchy of Innovation Capability and Inter-city Linkages of Knowledge in Post-reform China

The 2000s has witnessed increasing interests in cities′role of innovation in the era of knowledge-based economy.Compared with substantial empirical analysis on the world city hierarchy of innovation,this paper attempts to examine the national urban hierarchy of innovation capability in China,in terms of ranking systems,spatial pattern and inter-city linkages of knowledge during the post-reform period since the late 1970s.Based on quantitative analysis such as principal component factor analysis and clustering analysis,this paper identifies the five-tier hierarchy of in-novation,which is headed by Beijing and Shanghai,followed by the capital cities of each province and regional centre cities.The development of China′s urban hierarchy of innovation capability has been driven by such factors as the scale of innovation,scientific scale,innovation potential and innovation environment.The paper further investigates the inter-city linkages of knowledge measured by the number of co-authored papers among the cities.Beijing is positioned in the central position of the knowledge diffusion and knowledge cooperation innovation.More knowledge diffusion among high level cities has occurred than that among the low level cities as well as between the low level cities and high level cities,and provincial capital cities and the regional central cities.

CD133^+ gallbladder carcinoma cells exhibit self-renewal ability and tumorigenicity

AIM： To identify cancer stern cells （CSCs） in human gallbladder carcinomas （GBCs）. METHODS： Primary GBC cells were cultured under serum-free conditions to produce floating spheres. The stem-cell properties of the sphere-forming cells, including self-renewal, differentiation potential, chemoresistance and tumorigenicity, were determined in vitro or in vivo. Cell surface expression of CD133 was investigated in primary tumors and in spheroid cells using flow cytometry. The sphere-colony-formation ability and tumorigenicity of CD133＋ cells were assayed.floating spheroids were generated from primary GBC cells, and these sphere-forming cells could generate new progeny spheroids in serum-free media. Spheroid cells were differentiated under serum-containing conditions with downregulation of the stem cell markers Oct-4, Nanog, and nestin （P 〈 0.05）. The differentiated cells showed lower spheroid-colony-formation ability than the original spheroid cells （P 〈 0.05）. Spheroid ceils were more resistant to chemotherapeutic reagents than the congenetic adherent cells （P 〈 0.05）. Flow cytometry showed enriched CD133＋ population in sphereforming cells （P 〈 0.05）. CD133＋ cells possessed high colony-formation ability than the CD133 population （P 〈 0.01）. CD133＋ cells injected into nude mice revealed higher tumorigenicity than their antigen-negative counterparts （P 〈 0.05）. CONCLUSION： CD133 may be a cell surface marker for CSCs in GBC.

A Study on Theoretical Model and Applied Evaluation of Land Use Performance of High-tech Zone in Urban Fringe: A Case Study in Haidian District, Beijing

High-tech industrial zone is an important carrier for constructing innovative cities. It also plays an important role in implementing the national independent innovative strategy. How-ever, most of the high-tech industrial zones have many problems in their development process, such as efficiency of land use, weakness of oriented function and lack of land intensive. To solve these problems, the authors of this paper introduced the concept of land use performance and established the theoretical model to assess the land use performance of high-tech industrial zones. The model consists of the following three-dimensional parts: land use benefit, land use efficiency and innovative function. Based on this theory model, an index system which was composed of three secondary indictors, eight tertiary indictors and 37 fourth-grade indictors was set up to evaluate the land use performance of high-tech zone. To avoid the defects of plus model and function model, the authors brought out a three-dimensional evaluation model to examine the index of the land use performance of the high-tech industrial parks, which equals to the evaluation indicator system of land use performance of high-tech zone based on the above research. The authors examined the land use performance of five different high-tech industrial parks in Haidian District, Beijing City. The results indicated that the indicator system per-forms better in the aspect of evaluating land use benefit, land use efficiency and function of the high-tech industrial zone compared with other models.

Side population cells isolated from KATO Ⅲ human gastric cancer cell line have cancer stem cell-like characteristics

AIM: To investigate whether the side population (SP) cells possess cancer stem cell-like characteristics in vitro and the role of SP cells in tumorigenic process in gastric cancer. METHODS: We analyzed the presence of SP cells indifferent human gastric carcinoma cell lines, and then isolated and identified the SP cells from the KATO Ⅲ human gastric cancer cell line by flow cytometry. The clonogenic ability and self-renewal were evaluated by clone and sphere formation assays. The related genes were determined by reverse transcription polymerase chain reaction. To compare tumorigenic ability, SP and non-side population (NSP) cells from the KATO Ⅲ human gastric cancer cell line were subcutaneously injected into nude mice. RESULTS: SP cells from the total population accounted for 0.57% in KATO Ⅲ, 1.04% in Hs-746T, and 0.02% in AGS (CRL-1739). SP cells could grow clonally and have self-renewal capability in conditioned media. The expression of ABCG2, MDRI, Bmi-1 and Oct-4 was different between SP and NSP cells. However, there was no apparent difference between SP and NSP cells when they were injected into nude mice. CONCLUSION: SP cells have some cancer stem celllike characteristics in vitro and can be used for studying the tumorigenic process in gastric cancer.

On the college English course design and the training of innovation ability

This article is based on the theory of foreign language course design. It mainly introduces and analyzes the methods and mode of foreign English course design. The author thinks a competent foreign language teacher should try to carry out course design in scientific way, and to give play to their teaching personality and creativity and try to learn and to grasp the theory and the methods of foreign English course design and have a bold try and exploration and try to improve the ability of English teaching and only in this way we can foster the modern foreign language synthetical talent with the blazing new ideas.

Expansion of Technical Innovation and Demand Determines Production Organization Pattern in Strategic Emerging Industries——Taking Example of TFT-LCD Industry

Taking the evolution process of TFT-LCD industry as an example,this paper applied history-friendly model to analyze the effect of technology innovation and learning,and market demand growth and fluctuation on the evolution of production organization pattern in strategic emerging industries.Our research indicates that:(1) when market demand maintains linear growth,continuous technology innovation capabilities of vertically integrated enterprises in leading position of an industry are the key factor in deciding whether dominant production organization pattern will shift from vertical integration to specialization;(2) when market demand is in cyclical fluctuation,the technology learning capabilities of specialized enterprises in catch-up position are the key factor in deciding whether dominant production organization pattern will shift from vertical integration to specialization;(3) when market demand growth is under cyclical fluctuation,if the relative gap between technology innovation capabilities of vertically integrated enterprises and technology learning capabilities of specialized enterprises remains constant,the phase when industry cycle moves from trough to plateau is the best time window for specialized enterprises to catch up with and overtake vertically integrated enterprises.Hence,policy design supporting the development of strategic emerging industries should give full consideration to factors like market demand environment and technology innovation and learning capabilities of domestic enterprises.

Innovation and Technical Efficiency in the Smallholder Dairy Production System in Ethiopia

This study provides estimates of smallholder household＇s production efficiency and its determinants, and separately analyses the technical efficiency of dairy technology adopting and non-adopting farmers using data from Ethiopia. Cobb-Douglas stochastic frontier production function was modeled in the context of local level agricultural innovation systems framework and estimated using 2011 milk production data on 304 dairy farmers. Results show that the mean level of technical efficiency among the sampled farmers was about 26%. This result suggests that there is room for significant increases of production through reallocation of existing resources. Despite significant variation among farmers, these results also indicate only 19% of farmers have mean efficiency scores （_〉 50%）, implying a need to focus on creating innovation capacity that pushes the production frontier outward in the dairy production system. It is also revealed that individual farm households＇ efficiency varied widely across dairy technology adoption status, gender and districts. The significant gamma （g） statistic, of 0.9985 in the analysis indicates that about 99.85% variation in the output of milk production would be attributed to technical inefficiency effects （those under farmer＇s control） while only 0.0015% would be due to random effects, i.e., beyond the farmers control and hence calling for a focus on efficiency enhancing investments. Education, farm size, extension visit and off-farm income opportunity were found to be efficiency enhancing. The study recommends that different components of an agricultural innovation system have to interact to improve the innovation capacity of different actors and thereby improve the estimated technical inefficiencies.

A Historical Overview of China's Upgrading of Its Industrial Structure

This paper investigates the history of upgrade of industrial structure in human society from a combined perspective of economic and philosophical history encompassing primitive society,ancient society and recent and modern society.As far as recent and modern society is concerned,this paper divides the upgrade into two basic aspects:the shifting dominant position of primary,secondary and tertiary industries,and that of laborintensive,capital-intensive and knowledge-intensive industries.Moreover,this paper has examined the history of upgrade of industrial structure in China since 1949 and identified that the upgrade of China's industrial structure demonstrates not only the characteristics of middle and late stages of industrialization but characteristics of modernization as well.According to the general pattern of upgrade of industrial structure in recent and modern society and China's reality,great efforts must be made to improve China's indigenous innovation capacity,expedite agriculture modernization,increase competitiveness and qualitative development of manufacturing sector,and vigorously promote service sector(especially producers services),environmental protection industry,culture industry and maritime industry.

Developing newly emerging high-end industries in the low-carbon economy

Global warming has exerted severe challenges on the sustainable development of economic society and the food security,resource security,energy security and ecological security of the world.Low-carbon economy has become the current trend of the global economic development.Thus,the industrial development of China must seek the institutional innovation and technological innovation so as to improve the efficiency of energy.High-end industry has become the main factor of the future development of the economic society.Thus,to develop the high-end industry is an important approach to realize low-carbon economy.This paper explores the strategies of the development of newly emerging high-end industries against the background of low-carbon economy form such perspectives as effective use of resources,the improvement of independent innovative ability,and leading the high-end,high quality and high efficiency industries to the important region.

Financial crisis and sustainable development of Chinese manufacturing industry

Sub-prime lending crisis has become an international fi nancial crisis, which is evolving into an economic recession sweeping across the West. Financial crisis leads to the demand reduction in western countries, and as the largest manufacturing country, China must face overproduction. The role of China as "world factory" determines that fi nancial crisis will severely attack Chinese manufacturing industry. The unsustainable development of Chinese manufacturing industry is mainly reflected in the following aspects: heavy dependence on export, low-level manufacturing link, lack of modern service industry and high-tech industry, weak independent innovative ability, unsustainable exploration of heavy-pollution resources, and lack of international famous brands. How to transform crisis to opportunities is an urgent research topic. Under the circumstance of financial crisis, Chinese manufacturing industry has more external drives to change the current situation. Therefore, financial crisis becomes not only an opportunity for Chinese manufacturing industry to improve itself based on the existing accumulation but also a chance for China to transform from "world factory" into a powerful nation of manufacturing industry in the world.

Open Approach-Based Subject Matter： A New Aspect of Mathematical Activity Fostering Students＇ Creativity

This study compares the subject matter appeared on traditional Thai textbooks and Japanese textbooks and analyzes how extension and integration sequence on Japanese textbooks evokes students＇ mathematical creativity. The data were collected from the series of four lessons in the fifth grade by teaching experiment methodology conducted following the professional development project implemented lesson study and open approach in Thailand. The results show that extension and integration sequence is an appropriate subject matter to generate lesson for problem-solving classroom. The sequence of lesson leads students to excitement, curiosity, confidence and intimacy in mathematics that are powerful effects of mathematical creativity. Students can produce the different and various ways to solve problems that indicate their divergent thinking.

Research on the Current Condition of College Tourism Personnel Training Mode and Vocational Education Reforms

In this paper, we conduct research on the current condition of college tourism personnel training mode and vocational education reforms. Paying attention to the current social development innovation spirit, how to make students possess the necessary ability to innovate, is this the prime problem of the education. A lot of highly educated personnel in order to better adapt to social development and changes, constantly to learn knowledge, also has the characteristics of vocational college students. Our research combines the characteristics of the college tourism personnel training mode with the education reform which will enhance the performance of the teaching process.

Chinese Contemporary Art Design from the Perspective of National Culture

The progress of social economy drives the progress of humanity art. Due to historical condition reason, the pace of art design development in China is late. Since the reform and opening up, the art design obtains a long-term development in China. In order to adapt to the trend of world economy integration, all aspects of art design fields in China are learning from the foreign countries, however, it is hard to have a breakthrough creation in itself, and it lacks of domestic art design ＂localization＂ , which can not fully reflect the national culture and national elements. At the same time, the self-innovation power is weak, and the creation ability is insufficient, which also restricts the independent development of art design field to a higher level in China. The art design, as a comprehensive subject, is affected by many factors of society, science and technology and market for its own improvement. This paper mainly discusses from national culture level for art design, thinking that if the art design in China wants to develop higher, it needs to be based on the national culture and profound cultural base, constructing the art design products with Chinese national styles.

A new apparatus for investigating stress,deformation and seepage coupling properties of rock fractures

A true triaxial apparatus which is composed of three units was presented.The apparatus allows for investigations on deformation and seepage behaviors of a single rock fracture subjected to lateral stress and normal stress.The first unit has three jacks which can apply loads independently in three orthogonal directions.The second unit is used to supply water inflow,control seepage pressure and measure flow velocity in real time.The third unit is for measuring the normal deformation of rock fractures.Some tests for investigating the normal deformation and seepage behaviors of rock fractures subjected to normal and lateral loads on hard granite specimens with an artificial persistent fracture,were introduced.The results show that both the normal deformation and the hydraulic conductivity are influenced not only by the normal stress but also by the lateral stress.It is also shown that the aperture and the hydraulic conductivity decrease with the increasing normal stress but increase with the increasing lateral stress and both the aperture and the hydraulic conductivity obey exponential relationships with the normal stress and the lateral stress.

Theoretical Studies on Dehydrogenation Reactions in Mg2（BH4）2（NH2）2 Compounds

Borohydrides have been recently hightlighted as prospective new materials due to their high gravimetric capacities for hydrogen storage. It is, therefore, important to under- stand the underlying dehydrogenation mechanisms for further development of these ma- terials. We present a systematic theoretical investigation on the dehydrogenation mecha- nisms of the Mg2（BH4）2（NH2）2 compounds. We found that dehydrogenation takes place most likely via the intermolecular process, which is favorable both kinetically and thermo- dynamically in comparison with that of the intramolecular process. The dehydrogenation of Mg2（BH4）2（NH2）2 initially takes place via the direct combination of the hydridie H in BH4 and the protie H in NH2-, followed by the formation of Mg-H and subsequent ionic recombination of Mg-Hδ-…Hδ＋-N.

Therapeutic application of stem cells in gastroenterology:An up-date

Adult stem cells represent the self-renewing progenitors of numerous body tissues, and they are currently classified according to their origin and differentiation ability. In recent years, the research on stem cells has expanded enormously and holds therapeutic promises for many patients suffering from currently disabling diseases. This paper focuses on the possible use of stem cells in the two main clinical settings in gastro-enterology, i.e., hepatic and intestinal diseases, which have a strong impact on public health worldwide. Despite encouraging results obtained in both regenerative medicine and immunemediated conditions,further studies are needed to fully understand the biology of stem cellsand carefully assess their put ativeonco- genicproperties.Moreover,there searchonstemcellsarousesferventethical,socialandpoliticaldebate.TheItalianSocietyofGastroenterologysponsoredaworkshoponstemcellsheldinVeronaduringtheⅩⅥCongressoftheFederationofItalianSocietiesofDigestiveDiseases(March 6-9,2010).Here,we report on the issues discussed,including liver and intestinal diseases that may benefit from stemcell therapy,the biology of hepatic and intestinal tissue repair,and stem cell usage inclinical trials.