A 68-year-old male was complained of chest pain for two years and fatigue for one week. He was admitted to other hospitals two years ago because of severe chest pain. A diagnosis of acute non-ST segment elevation myoc...A 68-year-old male was complained of chest pain for two years and fatigue for one week. He was admitted to other hospitals two years ago because of severe chest pain. A diagnosis of acute non-ST segment elevation myocardial infarction （NSTEMI） was made. But the coronary angiography was refused by himself. After effective conservative treatment, he got better and discharged. A regular administration of aspirin, metoprolol and simvastatin was taken. No recurrent sympotoms occurred. However, he felt fatigue and palpitation after 30-m walking one week ago without predisposing factors.展开更多
We examine the time development of a wavepacket in a Non-Hermitian PT symmetric tight-bindingchain based on the Bethe ansatz solutions.The complete orthogonal sets in both unbroken and broken PT symmetryregions are es...We examine the time development of a wavepacket in a Non-Hermitian PT symmetric tight-bindingchain based on the Bethe ansatz solutions.The complete orthogonal sets in both unbroken and broken PT symmetryregions are established with respect to an inner product in terms of CPT conjugation.The dynamical development ofa stationary wavepacket is exhibited,showing the impacts from additional imaginary potentials within unbroken andbroken symmetric regimes.Our result indicates that there are distinct dynamic characteristics for both two regions.Theunbroken symmetric imaginary end potentials can be regarded as a special kind of boundary condition in the sense ofHermitian quantum mechanics.展开更多
Recently, inwardly propagating waves （called antiwaves, AWs） in nonlinear oscillatory systems have attracted much attention. An interesting negative refraction phenomenon has been observed in a bidomain system where...Recently, inwardly propagating waves （called antiwaves, AWs） in nonlinear oscillatory systems have attracted much attention. An interesting negative refraction phenomenon has been observed in a bidomain system where one medium supports forwardly propagating waves （normal waves, NWs） and the other AWs. In this paper we find that negative refraction （NR） in nonlinear media has an asymmetric property, i.e., NR can be observed only by applying wave source with proper frequency to one medium, but not the other. Moreover, NR appears always when the incident waves are dense and the refractional waves are sparse. This asymmetry is a particular feature for nonlinear NR, which can neither be observed in linear refraction processes （both positive and negative refractions） nor in nonlinear positive refraction. The mechanism underlying the asymmetry of nonlinear NR are fully understood based on the competition of nonlinear waves.展开更多
Over all fuel condition and the money we spend on the said fuel leads us to think about savings. What can we do？ As individuals, we can educate our students and their family members. The easiest way to do that is to ...Over all fuel condition and the money we spend on the said fuel leads us to think about savings. What can we do？ As individuals, we can educate our students and their family members. The easiest way to do that is to monitor their weekly spending for them. Together with their family members, the students have to monitor the consumption of electrical energy through three weeks. In the first week, they should spend electricity as they do everyday. During the second week they have the increase of spending of electrical energy. The third week is the saving energy week. They have to make a plan with their family members on how to save energy, for example, turning offthe lights in the empty rooms, turning offthe TV when there is no one watching it, etc.. Every week they have to note the data in kilowatts. When they acquire all the information and transform it into money they can see if it＇s worth saving electrical energy or not. They will see they don＇t have to give up the comforts of the modern life. The value of the project is in the fact that many households continue with the electrical energy saving. In fact, the number of the households is increasing.展开更多
When you go to Fashion Week,the talk is all about what’s trending in colors,cuts,hemlines,and finishes.When you go to retail seminars,it＇s about data.And how artificial intelligence（AI）,machine learning,
Interleukin-lbeta （IL-1β） is a cytokine involved in the control of inflammatory responses. The functions of IL-1β have been extensively studied in many vertebrates. However, few studies focused on the functions of...Interleukin-lbeta （IL-1β） is a cytokine involved in the control of inflammatory responses. The functions of IL-1β have been extensively studied in many vertebrates. However, few studies focused on the functions of IL-1β in the spotted halibut （Verasper variegatus）, an endangered aquatic fish that easily suffers from bacterial and viral infections. We first cloned and sequenced the IL-1β gene from V. variegatus （VvIL-1β）. Its conservative interleukin-1 propeptide and interleukin-1/18 domains corresponding regions, characteristics of the IL-1 protein family and TA-rich motifs relating to inflammatory responses were similar to those of the IL-1β genes from other teleost and mammals. The phylogenetic analysis showed that VvIL-1β was homologous to the IL-1β gene of other vertebrates. Treatment with pathogen-associated molecular patterns （PAMPs） induced a significant and rapid up-regulation of VvIL-1β expression in the peripheral blood leukocytes （PBLs）, revealing that VvIL-1β is actively involved in the host ilmnune responses against bacterial and viral pathogens. The expression level of VvIL-1β was relatively high in the PBLs, gill, and intestine, indicating the immunological function of VvIL-1β . VvIL-1β also had interesting expression patterns at specific developmental stages, implying that the IL-1β of flatfishes may have some novel functions during embryonic development and metamorphosis. The 3D structure prediction also provided information about how VvIL-113 interacts with its receptor protein. These results suggested that VvIL-1β may have multiple functions in V. variegatus and provided us valuable information for understanding the novel functions of IL- 1β.展开更多
Objective Intravenous administration of basic fibroblast growth factor （bFGF） is effective to reduce the volume of cerebral infract due to ischemia. This study was designed to investigate the molecular mechanism, es...Objective Intravenous administration of basic fibroblast growth factor （bFGF） is effective to reduce the volume of cerebral infract due to ischemia. This study was designed to investigate the molecular mechanism, especially the signal transduction pathways, involved in this protective role of bFGF. Methods Anoxia-reoxygenation treated atrocytes were used to study the role of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase （MAPK/ERK kinase, MEK）-ERK signaling pathway after exogenous bFGF administration by Western blot. Electrophoretic mobile shift assay was used to detect the binding activity of early growth response factor-1 （Egr-1）, an important transcription factor for endogenous bFGF. Results bFGF could protect some signal transduction proteins from the oxygen-derived free radicals induced degradation. ERK1/2 was activated and involved in Egr-1 binding activity enhancement induced by exogenous bFGF. Conclusion MEK-ERK MAPK cascade may be an important signal transduction pathway contributed to bFGF induced enhancement of Egr-1 binding activity in anoxia-reoxygenation injured astrocytes.展开更多
A nonlinear lateral-torsional coupled vibration model of a planetary gear system was established by taking transmission errors,time varying meshing stiffness and multiple gear backlashes into account.The bifurcation d...A nonlinear lateral-torsional coupled vibration model of a planetary gear system was established by taking transmission errors,time varying meshing stiffness and multiple gear backlashes into account.The bifurcation diagram of the system's motion state with rotational speed of sun gear was conducted through four steps.As a bifurcation parameter,the effect of rotational speed on the bifurcation properties of the system was assessed.The study results reveal that periodic motion is the main motion state of planetary gear train in low speed region when ns<2 350 r/min,but chaos motion state is dominant in high speed region when ns>2 350 r/min,The way of periodic motion to chaos is doubling bifurcation.There are two kinds of unstable modes and nine unstable regions in the speed region when 1 000 r/min<ns<3 000 r/min.展开更多
Satellite communication networks have been evolving from standalone networks with ad-hoc infrastructures to possibly interconnected portions of a wider Future Internet architecture. Experts belonging to the fifth-gene...Satellite communication networks have been evolving from standalone networks with ad-hoc infrastructures to possibly interconnected portions of a wider Future Internet architecture. Experts belonging to the fifth-generation(5 G) standardization committees are considering satellites as a technology to integrate in the 5 G environment. Software Defined Networking(SDN) is one of the paradigms of the next generation of mobile and fixed communications. It can be employed to perform different control functionalities, such as routing, because it allows traffic flow identification based on different parameters and traffic flow management in a centralized way. A centralized set of controllers makes the decisions and sends the corresponding forwarding rules for each traffic flow to the involved intermediate nodes that practically forward data up to the destination. The time to perform this process in integrated terrestrial-satellite networks could be not negligible due to satellite link delays. The aim of this paper is to introduce an SDN-based terrestrial satellite network architecture and to estimate the mean time to deliver the data of a new traffic flow from the source to the destination including the time required to transfer SDN control actions. The practical effect is to identify the maximum performance than can be expected.展开更多
Sea surface winds （SSWs） are vital to many meteorological and oceanographic applications, especially for regional study of short-range forecasting and Numerical Weather Prediction （NWP） assimilation. Spaceborne se...Sea surface winds （SSWs） are vital to many meteorological and oceanographic applications, especially for regional study of short-range forecasting and Numerical Weather Prediction （NWP） assimilation. Spaceborne seatterometers can provide global ocean surface vector wind products at high spatial resolution. However, given the limited spatial coverage and revisit time for an individual sensor, it is valuable to study improvements of multiple microwave scatterometer observations, including the advanced scatterometer onboard parallel satellites MetOp-A （ASCAT-A） and MetOp-B （ASCAT-B） and microwave scatterometers aboard Oceansat-2 （OSCAT） and HY-2A （HY2-SCAT）. These four scatterometer-derived wind products over the China Seas （0°-40°N, 105°-135°E） were evaluated in terms of spatial coverage, revisit time, bias of wind speed and direction, after comparison with ERA-Interim forecast winds from the European Centre for Medium-Range Weather Forecasts （ECMWF） and spectral analysis of wind components along the satellite track. The results show that spatial coverage of wind data observed by combination of the four sensors over the China Seas is about 92.8% for a 12-h interval at 12：00 and 90.7% at 24：00, respectively. The analysis of revisit time shows that two periods, from 5：30-8：30 UTC and 17：00-21：00 UTC each day, had no observations in the study area. Wind data observed by the four sensors along satellite orbits in one month were compared with ERA-Interim data, indicating that bias of both wind speed and direction varies with wind speed, especially for speeds less than 7 m/s. The bias depends on characteristics of each satellite sensor and its retrieval algorithm for wind vector data. All these results will be important as guidance in choosing the most suitable wind product for applications and for constructing blended SSW products.展开更多
文摘A 68-year-old male was complained of chest pain for two years and fatigue for one week. He was admitted to other hospitals two years ago because of severe chest pain. A diagnosis of acute non-ST segment elevation myocardial infarction （NSTEMI） was made. But the coronary angiography was refused by himself. After effective conservative treatment, he got better and discharged. A regular administration of aspirin, metoprolol and simvastatin was taken. No recurrent sympotoms occurred. However, he felt fatigue and palpitation after 30-m walking one week ago without predisposing factors.
基金Support by the CNSF Grants Nos.10874091 and 2006CB921205
文摘We examine the time development of a wavepacket in a Non-Hermitian PT symmetric tight-bindingchain based on the Bethe ansatz solutions.The complete orthogonal sets in both unbroken and broken PT symmetryregions are established with respect to an inner product in terms of CPT conjugation.The dynamical development ofa stationary wavepacket is exhibited,showing the impacts from additional imaginary potentials within unbroken andbroken symmetric regimes.Our result indicates that there are distinct dynamic characteristics for both two regions.Theunbroken symmetric imaginary end potentials can be regarded as a special kind of boundary condition in the sense ofHermitian quantum mechanics.
基金Supported by the National Natural Science Foundation of China under Grant No.10675020the National 973 Nonlinear Science Project
文摘Recently, inwardly propagating waves （called antiwaves, AWs） in nonlinear oscillatory systems have attracted much attention. An interesting negative refraction phenomenon has been observed in a bidomain system where one medium supports forwardly propagating waves （normal waves, NWs） and the other AWs. In this paper we find that negative refraction （NR） in nonlinear media has an asymmetric property, i.e., NR can be observed only by applying wave source with proper frequency to one medium, but not the other. Moreover, NR appears always when the incident waves are dense and the refractional waves are sparse. This asymmetry is a particular feature for nonlinear NR, which can neither be observed in linear refraction processes （both positive and negative refractions） nor in nonlinear positive refraction. The mechanism underlying the asymmetry of nonlinear NR are fully understood based on the competition of nonlinear waves.
文摘Over all fuel condition and the money we spend on the said fuel leads us to think about savings. What can we do？ As individuals, we can educate our students and their family members. The easiest way to do that is to monitor their weekly spending for them. Together with their family members, the students have to monitor the consumption of electrical energy through three weeks. In the first week, they should spend electricity as they do everyday. During the second week they have the increase of spending of electrical energy. The third week is the saving energy week. They have to make a plan with their family members on how to save energy, for example, turning offthe lights in the empty rooms, turning offthe TV when there is no one watching it, etc.. Every week they have to note the data in kilowatts. When they acquire all the information and transform it into money they can see if it＇s worth saving electrical energy or not. They will see they don＇t have to give up the comforts of the modern life. The value of the project is in the fact that many households continue with the electrical energy saving. In fact, the number of the households is increasing.
文摘When you go to Fashion Week,the talk is all about what’s trending in colors,cuts,hemlines,and finishes.When you go to retail seminars,it＇s about data.And how artificial intelligence（AI）,machine learning,
基金supported by the National Natural Sciences Foundation of China(No.31101891)the Hitech Research and Development Program of China(No.2012AA10A408)
文摘Interleukin-lbeta （IL-1β） is a cytokine involved in the control of inflammatory responses. The functions of IL-1β have been extensively studied in many vertebrates. However, few studies focused on the functions of IL-1β in the spotted halibut （Verasper variegatus）, an endangered aquatic fish that easily suffers from bacterial and viral infections. We first cloned and sequenced the IL-1β gene from V. variegatus （VvIL-1β）. Its conservative interleukin-1 propeptide and interleukin-1/18 domains corresponding regions, characteristics of the IL-1 protein family and TA-rich motifs relating to inflammatory responses were similar to those of the IL-1β genes from other teleost and mammals. The phylogenetic analysis showed that VvIL-1β was homologous to the IL-1β gene of other vertebrates. Treatment with pathogen-associated molecular patterns （PAMPs） induced a significant and rapid up-regulation of VvIL-1β expression in the peripheral blood leukocytes （PBLs）, revealing that VvIL-1β is actively involved in the host ilmnune responses against bacterial and viral pathogens. The expression level of VvIL-1β was relatively high in the PBLs, gill, and intestine, indicating the immunological function of VvIL-1β . VvIL-1β also had interesting expression patterns at specific developmental stages, implying that the IL-1β of flatfishes may have some novel functions during embryonic development and metamorphosis. The 3D structure prediction also provided information about how VvIL-113 interacts with its receptor protein. These results suggested that VvIL-1β may have multiple functions in V. variegatus and provided us valuable information for understanding the novel functions of IL- 1β.
文摘Objective Intravenous administration of basic fibroblast growth factor （bFGF） is effective to reduce the volume of cerebral infract due to ischemia. This study was designed to investigate the molecular mechanism, especially the signal transduction pathways, involved in this protective role of bFGF. Methods Anoxia-reoxygenation treated atrocytes were used to study the role of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase （MAPK/ERK kinase, MEK）-ERK signaling pathway after exogenous bFGF administration by Western blot. Electrophoretic mobile shift assay was used to detect the binding activity of early growth response factor-1 （Egr-1）, an important transcription factor for endogenous bFGF. Results bFGF could protect some signal transduction proteins from the oxygen-derived free radicals induced degradation. ERK1/2 was activated and involved in Egr-1 binding activity enhancement induced by exogenous bFGF. Conclusion MEK-ERK MAPK cascade may be an important signal transduction pathway contributed to bFGF induced enhancement of Egr-1 binding activity in anoxia-reoxygenation injured astrocytes.
基金Project(50775108) supported by the National Natural Science Foundation of China
文摘A nonlinear lateral-torsional coupled vibration model of a planetary gear system was established by taking transmission errors,time varying meshing stiffness and multiple gear backlashes into account.The bifurcation diagram of the system's motion state with rotational speed of sun gear was conducted through four steps.As a bifurcation parameter,the effect of rotational speed on the bifurcation properties of the system was assessed.The study results reveal that periodic motion is the main motion state of planetary gear train in low speed region when ns<2 350 r/min,but chaos motion state is dominant in high speed region when ns>2 350 r/min,The way of periodic motion to chaos is doubling bifurcation.There are two kinds of unstable modes and nine unstable regions in the speed region when 1 000 r/min<ns<3 000 r/min.
文摘Satellite communication networks have been evolving from standalone networks with ad-hoc infrastructures to possibly interconnected portions of a wider Future Internet architecture. Experts belonging to the fifth-generation(5 G) standardization committees are considering satellites as a technology to integrate in the 5 G environment. Software Defined Networking(SDN) is one of the paradigms of the next generation of mobile and fixed communications. It can be employed to perform different control functionalities, such as routing, because it allows traffic flow identification based on different parameters and traffic flow management in a centralized way. A centralized set of controllers makes the decisions and sends the corresponding forwarding rules for each traffic flow to the involved intermediate nodes that practically forward data up to the destination. The time to perform this process in integrated terrestrial-satellite networks could be not negligible due to satellite link delays. The aim of this paper is to introduce an SDN-based terrestrial satellite network architecture and to estimate the mean time to deliver the data of a new traffic flow from the source to the destination including the time required to transfer SDN control actions. The practical effect is to identify the maximum performance than can be expected.
基金Supported by the Shandong Joint Fund for Marine Science Research Centers(No.U1406404)the National High Technology Research and Development Program of China(No.2013AA09A505)the National Basic Research Program of China(973 Program)(No.2012CB955600)
文摘Sea surface winds （SSWs） are vital to many meteorological and oceanographic applications, especially for regional study of short-range forecasting and Numerical Weather Prediction （NWP） assimilation. Spaceborne seatterometers can provide global ocean surface vector wind products at high spatial resolution. However, given the limited spatial coverage and revisit time for an individual sensor, it is valuable to study improvements of multiple microwave scatterometer observations, including the advanced scatterometer onboard parallel satellites MetOp-A （ASCAT-A） and MetOp-B （ASCAT-B） and microwave scatterometers aboard Oceansat-2 （OSCAT） and HY-2A （HY2-SCAT）. These four scatterometer-derived wind products over the China Seas （0°-40°N, 105°-135°E） were evaluated in terms of spatial coverage, revisit time, bias of wind speed and direction, after comparison with ERA-Interim forecast winds from the European Centre for Medium-Range Weather Forecasts （ECMWF） and spectral analysis of wind components along the satellite track. The results show that spatial coverage of wind data observed by combination of the four sensors over the China Seas is about 92.8% for a 12-h interval at 12：00 and 90.7% at 24：00, respectively. The analysis of revisit time shows that two periods, from 5：30-8：30 UTC and 17：00-21：00 UTC each day, had no observations in the study area. Wind data observed by the four sensors along satellite orbits in one month were compared with ERA-Interim data, indicating that bias of both wind speed and direction varies with wind speed, especially for speeds less than 7 m/s. The bias depends on characteristics of each satellite sensor and its retrieval algorithm for wind vector data. All these results will be important as guidance in choosing the most suitable wind product for applications and for constructing blended SSW products.
