AIM: To investigate the effects of fibrin sealant on hemostasis and liver regeneration and intra-abdominal adhesions in an experimental liver injury. METHODS: Thirty-six Wistar rats were randomly divided into primary ...AIM: To investigate the effects of fibrin sealant on hemostasis and liver regeneration and intra-abdominal adhesions in an experimental liver injury. METHODS: Thirty-six Wistar rats were randomly divided into primary suture group (n = 15), fibrin sealant group (n = 15) and control group (n = 6). A wedge resection was performed on the left lobe of the liver. In primary suture group, liver was sutured using polypropylene material, while fibrin glue was administrated on the liver surface in fibrin sealant group. RESULTS: More intra-abdominal adhesions were observed in the primary suture group compared to the fibrin sealant group on 3rd (2.50 ± 0.5 vs 0.25 ± 0.5, P = 0.015), 10th (2.75 ± 0.5 vs 0.50 ± 0.6, P = 0.06) and 20th (1.75 ± 0.5 vs 0.70 ± 0.5, P = 0.015) postoperative days. Histopathological scores were better in the fibrin sealant group in comparison with the primary suture group on 3rd (8.75 ± 0.5 vs 6.75 ± 0.5, P = 0.006), 10th (7.50 ± 1.0 vs 5.5 ± 0.6, P = 0.021) and 20th (6.40 ± 1.7 vs 3.20 ± 1.6, P = 0.025) postoperative days. CONCLUSION: Out data suggest that fibrin sealant is preferred over primary suture in appropriate cases including liver trauma since it causes less intra-abdominal adhesions while allowing shorter hemostasis time as assessed in experimental liver trauma.展开更多
A comparison of the effectiveness of installing reactive power compensators,such as shunt capacitors,static var compensators(SVCs),and static synchronous compensators(STATCOMs),was presented in large-scale power netwo...A comparison of the effectiveness of installing reactive power compensators,such as shunt capacitors,static var compensators(SVCs),and static synchronous compensators(STATCOMs),was presented in large-scale power networks.A suitable bus was first identified using modal analysis method.The single shunt capacitor,single SVC,and single STATCOM were installed separately on the most critical bus.The effects of the installation of different devices on power loss reduction,voltage profile improvement,and voltage stability margin enhancement were examined and compared for 57-and 118-bus transmission systems.The comparative study results show that SVC,and STATCOM are expensive compared to shunt capacitor,yet the effect of installing STATCOM is better than SVC and the effect of installing SVC is better than that of shunt capacitor in achieving power loss reduction,voltage profile improvement and voltage stability margin enhancement.展开更多
The dynamic reactive power compensation equipment in Jiuquan Wind Power Base of above 10 GW consists of three different types of compensation devices, including: static var generator (SVG), thyristor controlled com...The dynamic reactive power compensation equipment in Jiuquan Wind Power Base of above 10 GW consists of three different types of compensation devices, including: static var generator (SVG), thyristor controlled compensator (TGR) and magnetically controlled reactor (MGR). The lack of experimental verification of performance is not conducive to voltage/var management or full utilization of device capaci- ties. In order to solve the above problems, the compensation device performance test was performed. The test items and procedures were selected based on related national standards with the consideration for different grid structures and wind farm operation modes. The testing contents included dynamic regulating range, active power loss, dynamic response time, and harmonic voltage level. Three types of compensation devices installed in different wind farms, namely SVG, TCR and MCR, were chosen and tested. The performances were compared and analyzed according to the field test results.展开更多
Ischemic preconditioning and postconditioning distinctly attenuate ventricular arrhythmia after ischemia without affecting the severity of myocardial stunning. Therefore, we report the effects of sevofiurane precondit...Ischemic preconditioning and postconditioning distinctly attenuate ventricular arrhythmia after ischemia without affecting the severity of myocardial stunning. Therefore, we report the effects of sevofiurane preconditioning and postconditioning on stunned myocardium in isolated rat hearts. Isolated rat hearts were underwent 20 min of global ischemia and 40 min of reperfusion. After an equilibration period (20 min), the hearts in the preconditioning group were exposed to sevoflurane for 5 min and next washout for 5 min before ischemia. Hearts in the sevoflurane postconditioning group underwent equilibration and ischemia, followed immediately by sevoflurane exposure for the first 5 min of reperfusion. The control group received no treatment before and after ischemia. Left ventricular pressure, heart rate, coronary flow, electrocardiogram, and tissue histology were measured as variables of ventricular function and cellular injury, respectively. There was no significant difference in the duration of reperfusion ventricular arrhythmias between control and sevoflurane preconditioning group (P=0.195). The duration of reperfusion ventricular arrhythmias in the sevoflurane postconditioning group was significantly shorter than that in the other two groups (P〈0.05). +(dPIdt)max in the sevoflurane preconditioning group at 5, 10, 15, 20, and 30 min after reperfusion was significantly higher than that in the control group (P〈0.05), and there were no significant differences at 40 min after reperfusion among the three groups (P〉0.05). As expected, for a 20-min general ischemia, infarct size in heart slices determined by 2,3,5-triphenyltetrazolium chloride staining among the groups was not obvious. Sevofiurane postconditioning reduces reperfusion arrhythmias without affecting the severity of myocardial stunning. In contrast, sevoflurane preconditioning has no beneficial effects on reperfusion arrhythmias, but it is in favor of improving ventricular function and recovering myocardial stunning. Sevoflurane preconditioning and postconditioning may be useful for correcting the stunned myocardium.展开更多
To probe into effective surgical procedures and improve the outcome of treatment for patients with severe hepatic injury. Methods: A retrospective study involving 113 patients with seve re hepatic trauma (AAST grade I...To probe into effective surgical procedures and improve the outcome of treatment for patients with severe hepatic injury. Methods: A retrospective study involving 113 patients with seve re hepatic trauma (AAST grade IV and V) during the past 12 years was carried out . Ninety eight patients underwent surgical treatment. Surgical interventions in cluding hepatectomy or direct control of bleeding vessels by finger fracture tec hnique with Pringle maneuver, selective ligation of hepatic artery, retrohepatic caval repair with total hepatic vascular occlusion, and perihepatic packing wer e mainly used. Results: In the 98 patients treated operatively, the survival r ate was 69.4 % (68/98). Among 40 patients with juxtahepatic venous injury (JH VI), 15 were cured with the maximum blood transfusion of 12 000 ml. Eight ca ses of Grade IV injury treated nonoperatively were cured. The percentage of fail ure of nonoperative management was 42.9 % (6/14). The overall mortality rate was 32.7 % (37/113), and 57% of the deaths were due to exsanguination. Conclusions: Reasonable surgical procedures based on classifica tion of hepatic injuries can increase the survival rate of severe liver trauma. Accurate perihepatic packing is effective in dealing with JHVI.展开更多
文摘AIM: To investigate the effects of fibrin sealant on hemostasis and liver regeneration and intra-abdominal adhesions in an experimental liver injury. METHODS: Thirty-six Wistar rats were randomly divided into primary suture group (n = 15), fibrin sealant group (n = 15) and control group (n = 6). A wedge resection was performed on the left lobe of the liver. In primary suture group, liver was sutured using polypropylene material, while fibrin glue was administrated on the liver surface in fibrin sealant group. RESULTS: More intra-abdominal adhesions were observed in the primary suture group compared to the fibrin sealant group on 3rd (2.50 ± 0.5 vs 0.25 ± 0.5, P = 0.015), 10th (2.75 ± 0.5 vs 0.50 ± 0.6, P = 0.06) and 20th (1.75 ± 0.5 vs 0.70 ± 0.5, P = 0.015) postoperative days. Histopathological scores were better in the fibrin sealant group in comparison with the primary suture group on 3rd (8.75 ± 0.5 vs 6.75 ± 0.5, P = 0.006), 10th (7.50 ± 1.0 vs 5.5 ± 0.6, P = 0.021) and 20th (6.40 ± 1.7 vs 3.20 ± 1.6, P = 0.025) postoperative days. CONCLUSION: Out data suggest that fibrin sealant is preferred over primary suture in appropriate cases including liver trauma since it causes less intra-abdominal adhesions while allowing shorter hemostasis time as assessed in experimental liver trauma.
文摘A comparison of the effectiveness of installing reactive power compensators,such as shunt capacitors,static var compensators(SVCs),and static synchronous compensators(STATCOMs),was presented in large-scale power networks.A suitable bus was first identified using modal analysis method.The single shunt capacitor,single SVC,and single STATCOM were installed separately on the most critical bus.The effects of the installation of different devices on power loss reduction,voltage profile improvement,and voltage stability margin enhancement were examined and compared for 57-and 118-bus transmission systems.The comparative study results show that SVC,and STATCOM are expensive compared to shunt capacitor,yet the effect of installing STATCOM is better than SVC and the effect of installing SVC is better than that of shunt capacitor in achieving power loss reduction,voltage profile improvement and voltage stability margin enhancement.
文摘The dynamic reactive power compensation equipment in Jiuquan Wind Power Base of above 10 GW consists of three different types of compensation devices, including: static var generator (SVG), thyristor controlled compensator (TGR) and magnetically controlled reactor (MGR). The lack of experimental verification of performance is not conducive to voltage/var management or full utilization of device capaci- ties. In order to solve the above problems, the compensation device performance test was performed. The test items and procedures were selected based on related national standards with the consideration for different grid structures and wind farm operation modes. The testing contents included dynamic regulating range, active power loss, dynamic response time, and harmonic voltage level. Three types of compensation devices installed in different wind farms, namely SVG, TCR and MCR, were chosen and tested. The performances were compared and analyzed according to the field test results.
基金Project supported by the National Natural Science Foundation of China (No. 30772090)the Natural Science Foundation of Zhejiang Province (No. Y204141)+1 种基金the Foundation from Science and Tech-nology Department of Zhejiang Province (No. 2007R10034)the Foundation from the Health Bureau of Zhejiang Province (No. 2007QN007), China
文摘Ischemic preconditioning and postconditioning distinctly attenuate ventricular arrhythmia after ischemia without affecting the severity of myocardial stunning. Therefore, we report the effects of sevofiurane preconditioning and postconditioning on stunned myocardium in isolated rat hearts. Isolated rat hearts were underwent 20 min of global ischemia and 40 min of reperfusion. After an equilibration period (20 min), the hearts in the preconditioning group were exposed to sevoflurane for 5 min and next washout for 5 min before ischemia. Hearts in the sevoflurane postconditioning group underwent equilibration and ischemia, followed immediately by sevoflurane exposure for the first 5 min of reperfusion. The control group received no treatment before and after ischemia. Left ventricular pressure, heart rate, coronary flow, electrocardiogram, and tissue histology were measured as variables of ventricular function and cellular injury, respectively. There was no significant difference in the duration of reperfusion ventricular arrhythmias between control and sevoflurane preconditioning group (P=0.195). The duration of reperfusion ventricular arrhythmias in the sevoflurane postconditioning group was significantly shorter than that in the other two groups (P〈0.05). +(dPIdt)max in the sevoflurane preconditioning group at 5, 10, 15, 20, and 30 min after reperfusion was significantly higher than that in the control group (P〈0.05), and there were no significant differences at 40 min after reperfusion among the three groups (P〉0.05). As expected, for a 20-min general ischemia, infarct size in heart slices determined by 2,3,5-triphenyltetrazolium chloride staining among the groups was not obvious. Sevofiurane postconditioning reduces reperfusion arrhythmias without affecting the severity of myocardial stunning. In contrast, sevoflurane preconditioning has no beneficial effects on reperfusion arrhythmias, but it is in favor of improving ventricular function and recovering myocardial stunning. Sevoflurane preconditioning and postconditioning may be useful for correcting the stunned myocardium.
文摘To probe into effective surgical procedures and improve the outcome of treatment for patients with severe hepatic injury. Methods: A retrospective study involving 113 patients with seve re hepatic trauma (AAST grade IV and V) during the past 12 years was carried out . Ninety eight patients underwent surgical treatment. Surgical interventions in cluding hepatectomy or direct control of bleeding vessels by finger fracture tec hnique with Pringle maneuver, selective ligation of hepatic artery, retrohepatic caval repair with total hepatic vascular occlusion, and perihepatic packing wer e mainly used. Results: In the 98 patients treated operatively, the survival r ate was 69.4 % (68/98). Among 40 patients with juxtahepatic venous injury (JH VI), 15 were cured with the maximum blood transfusion of 12 000 ml. Eight ca ses of Grade IV injury treated nonoperatively were cured. The percentage of fail ure of nonoperative management was 42.9 % (6/14). The overall mortality rate was 32.7 % (37/113), and 57% of the deaths were due to exsanguination. Conclusions: Reasonable surgical procedures based on classifica tion of hepatic injuries can increase the survival rate of severe liver trauma. Accurate perihepatic packing is effective in dealing with JHVI.