“法考”制度改革背景下地方高校工程法律人才培养模式创新研究

“国家统一法律职业资格考试”制度改革的落地落实,导致地方高校工程法律人才培养的外部环境发生重大变化,法学与工程课程体系的深度复合、工程法律人才实践能力培养和人文素质教育等问题亟需探讨解决。通过对东南大学、长沙理工大学、湖南理工学院和福建工程学院等院校工程法律人才培养模式的对比分析,地方高校的工程法律人才培养模式创新主要进路为:第一,培养法科生的工程素养与知识,挖掘法学与工程学的最大结合潜力;第二,重视法律实践能力的养成,以校地合作作为地方高校工程法律人才实践能力培养的新动力;第三,合理设置德育课程及其比重,以充沛的人文知识和伦理素养作为工程法律人才的坚实道德基础。

Effects of Temperature on Determination of Protein Concentration with Coomassie Brilliant Blue Method

[Objective] This study aimed to investigate the effects of temperature on determination of protein concentration with Coomassie Brilliant Blue method,thus proving advice and guidance for accurate determination of protein concentration.[Method] With Coomassie Brilliant Blue method,the concentrations of different bovine serum albumin samples were determined under different temperatures and incubation time.[Result] According to the standard curve,when the determination range of protein concentration was 0-100 mg/ml,the determined protein concentration was relatively stable after incubation at 20 ℃ for 20-30 min.Furthermore,the determination result of higher protein concentration with Coomassie Brilliant Blue method was less affected by various factors.[Conclusion] In determination of protein concentration with Coomassie Brilliant Blue method,temperature,sample concentration and incubation time were important factors affecting the accuracy of experimental results.

A self-adaptive algorithm for choosing reference velocities in the presence of lateral velocity variations

Based on perturbation theory, the wave equation extrapolation operator with mixed domains has the ability to deal with lateral velocity variations. It is the image method that has undergone much research in seismology. All extrapolation operators face the problem of choosing the reference velocity due to continuation in depth. The wavefield extrapolation operator with a single reference velocity is suitable for media with weak lateral variation. The multi-reference velocity extrapolation operator can cope with severe lateral velocity variations and improve image accuracy. However, the calculation cost is large. We present a self-adaptive approach to automatically determine the number of selected reference velocities according to the complexity of structure and the given velocity threshold value. The approach can be used to construct the SSF, FFD, WXFD, and GSP multi-reference velocity wavefield extrapolation image algorithms. The result of a salt-dome model data test demonstrates that the self-adoptive multi-reference wavefield extrapolation algorithm has the ability to deal with severe lateral velocity variations and can also be used for structure edge detection. The method is flexible and computationally cost-effective.

Flexible Calibration Method for 3D Laser Scanner System

In this paper, a flexible high-precision calibration method suitable for industrial field was proposed. The complexity of the coordinate transformation was simplified by choosing the camera coordinate system as the unified reference coordinate system. A flexible planar calibration pattern was introduced to the calibration process, which can be arbitrarily placed and from which the known feature points can be extracted to construct other unknown feature points. With the known intrinsic parameters, the laser projector plane equation was fitted by the multi-noncollinear points, which were acquired through the principle of triangulation and the projective invariance of cross ratio. With this method, the strict alignment and multiple times of coordinate transformation can be avoided. Experimental results showed that the arithmetic mean of the root mean square(RMS) error of distance was 0.000 7 mm.

Parametric study of gas−liquid two-phase flow field in horizontal stirred tank

Based on Fluent software,the gas−liquid two-phase flow in the horizontal stirred tank was simulated with SST k−ωturbulence model,Eulerian−Eulerian two-fluid model,and multi-reference flame method.The mixing process in the tank was calculated by tracer method.The results show that increasing the rotating speed or gas flow is conducive to a more uniform distribution of the gas phase and accelerates the mixing of the liquid phase.When the rotating speed exceeds 93 r/min,the relative power demand remains basically constant.The change in the inclination angle of the upper impeller has minimal effect on the gas phase distribution.When the inclination angle is 50°,the relative power demand reaches the maximum.An appropriate increase in the impeller distance from the bottom improves the gas holdup and gas phase distribution but increases the liquid phase mixing time.

Comparison of high-resolution ultrasound and MR-enterography in patients with inflammatory bowel disease

AIM:To compare the results of high-resolution ultrasound(HR-US) and magnetic resonance enterography(MRE) examinations in patients with inflammatory bowel disease(IBD).METHODS:The reports of 250 consecutive cases with known IBD,who had an MRE and HR-US examination,were retrospectively analyzed.Using a patient-based approach we evaluated morphological disease features such as affected bowel wall,stenosis,abscess and fistula.The comparison between the two modalities was based on the hypothesis,that any pathological change described in any imaging modality was a true finding,as no further standard of reference was available for complete assessment.RESULTS:Two hundred and fifty examinations representing 207 different patients were evaluated.Both modalities assessed similar bowel wall changes in 65% of the examinations,with more US findings in 11% and more MRE findings in 15%.When the reports were analyzed with regard to "bowel wall inflammation",US reported more findings in 2%,while MRE reported more findings in 53%.Stenoses were assessed to be identical in 8%,while US found more in 3% and MRE in 29%(P < 0.01).For abscess detection,US showed more findings in 2%(n = 4) while MRE detected more in 6%(n = 16).US detected more fistulas in 1%(n = 2),while MRE detected more in 13%(n = 32)(P < 0.001).The most common reason for no detected pathology by US was a difficult to assess anatomical region(lesser pelvis,n = 72).CONCLUSION:US can miss clinically relevant pathological changes in patients with IBD mostly due to difficulty in assessing certain anatomical regions.

Effects of visuals on simulated CET-3 listening test

In real-time situation, listeners rely on linguistic knowledge as well as contextual information to process acoustic signals, while presently in China, most listening comprehension tests do not include visuals （visuals bearing content or contextual information） to facilitate the listening. The present paper chooses several simulated CET-3 listening comprehension as the experimental materials and tries to investigate the effects of different types of visuals, such as pictures, diagrams, and photos of the speakers＇ part, with items on the CET-3 listening tests.

Optical Fiber Pressure Sensor with Reference Channel

The principle of optical fiber pressure sensing probe with common diaphragm and the method for stabilizing the laser diodes are described in this paper at first.Then we discussed the improvement in characteristics of the system by means of taking the techniques of reference light channel and ratio measurement.

Coherence through theme equivalence： With reference to text translation

Theme is the point of departure of a message, and it is a textual phenomenon. It can interpret the comprehension and production of texts. This paper first makes a thematic analysis of the English original text and the Chinese target text, and then makes a comparative study of them in terms of the textual properties. It is found that in reproduction of target text, theme equivalence can not only help to realize the coherence of the target text with the same effect on receptors but also can save translation efforts. It is unnecessary to change the theme-rheme arrangements of the original unless it is required due to the social and cultural differences between English and Chinese.

Numerical method for estimation of kinematical parameters for articulated rovers on loose rough terrain

Based on the study of passive articulated rover,a complete suspension kinematics model from wheel to inertial reference frame is presented,which uses D-H method of manipulator and presentation with Euler angle of pitch,roll and yaw.An improved contact model is adopted aimed at the loose and rough lunar terrain.Using this kinematics model and numerical continuous and discrete Newton's method with iterative factor,the numerical method for estimation of kinematical parameters of articulated rovers on loose and rough terrain is constructed.To demonstrate this numerical method,an example of two torsion bar rocker-bogie lunar rover with eight wheels is presented.Simulation results show that the numerical method for estimation of kinematical parameters of articulated rovers based on improved contact model can improve the precision of kinematical estimation on loose and rough terrain and decrease errors caused by contact models established based on general hypothesis.

Body awareness therapy: A new strategy for relief of symptoms in irritable bowel syndrome patients

AIM: To compare irritable bowel syndrome (IBS) pa- tients with apparently healthy persons and to evaluate body awareness therapy, which is a physiotherapeutic remedy focusing on normalising tensions in the body, for the treatment of IBS with the hypothesis that altered body tension is associated with the syndrome. METHODS: Twenty-one IBS patients received body awareness therapy two hours weekly for 24 wk. At base- line as well as after 12 and 24 wk, they underwent ex- aminations including resource oriented body examination in combination with body awareness scale evaluation and f illed in gastrointestinal and psychological symptom questionnaires. Saliva cortisol was analysed. A group of 21 apparently healthy persons underwent the same ex- aminations once. RESULTS: Compared to the apparently healthy group, IBS patients scored higher at baseline for gastrointestinal and psychological symptoms. They showed more often alterations in normal body tension patterns, as well as deviating cortisol slopes in saliva. After 24 wk of body awareness therapy, their gastrointestinal and psychologi- cal symptoms were reduced overall. Somatic symptoms decreased in parallel with depressive symptoms. Whole body pain score decreased, coping ability as well as bio- chemical stress markers improved. CONCLUSION: IBS patients scored higher for gastroin- testinal and psychological symptoms, and presented with altered biochemical stress markers. Their body tension deviated compared to healthy controls. Furthermore,body awareness therapy gave relief of both somatic com- plaints, psychological symptoms and normalised body tension. These findings indicate that distorted tension constitutes an important part of the symptoms in IBS.

Direct Adaptive Fuzzy Based Backstepping Control of Semi Strict Feedback Nonlinear Systems

In this paper, a direct adaptive fuzzy tracking control is proposed for a class of uncertain single-input single-output nonlinear semi-strict feedback systems. Based on Takagi-Sugeno type fuzzy systems, a direct adaptive fuzzy tracking controller is developed by using the backstepping approach. The main advantage of the developed method is that for an n-th order system, only one parameter is needed to be adjusted online. It is proven that, under the appropriate assumptions, the developed scheme can achieve that the output system converges to a small neighborhood of the reference signal and all the signals in the closed-loop system remain bounded. The efficacy of the proposed algorithm is investigated by an illustrative simulation example of one link robot.

PD-1/PD-L1 pathway blockade works as an effective and practical therapy for cancer immunotherapy

Cancer immunotherapy has greatly advanced in recent years,and PD-1/PD-L1 blocking therapy has become a major pillar of immunotherapy.Successful clinical trials of PD-1/PD-L1 blocking therapies in cancer treatments have benefited many patients,which promoted the Food and Drug Administration(FDA)approval of PD-1/PD-L1 blocking drugs.In this review,we provide a detailed introduction of five PD-1/PD-L1 blocking drugs,with indications and studies,as a valuable reference for doctors and medical investigators.Moreover,the characteristics of PD-1/PD-L1 blocking therapies,including their universality and sustainability,are discussed in this review.Furthermore,we also discuss and predict the possibility of PD-L1 as an indication marker of PD-1/PD-L1 blocking therapy for pan-cancer treatment,and the current status of combination therapies.

Legal thinking under legal globalization and social transformation

China now is in an important period of social transformation, it puts forward unique requirements for changes from the ethics community to the legal social, and also for law operation, legal developments and public awareness of the laws. Law globalization both is a result of globalization in other areas, but also a tool to promote other areas of globalization, and its essence is the performance of the laws of all countries in the world being more interdependent to further strengthen. From a legal point to analysis, to identify the root causes and find ways to solve and to provide a useful reference for the current socialist harmonious society is very necessary.

A Method for Risky Multiple Attribute Decision Making with Four - dimensional Reference Point

A method based on cumulative prospect theory was proposed to solve risky multiple attribute decision making problems with Four -dimensional reference points. Considering the influence of different learning processes and corresponding features on decision-making, a new reference-learning behavior is added, and a risk-based multiple-attribute decision-making method based on four-dimensional reference point cumulative prospect theory is proposed. Firstly, according to the cumulative prospect theory, the prospect value and the decision function value of the four reference points of learning, time, evaluation value and expected value are calculated respectively, and the cumulative prospect value matrix of each program dynamic is formed. Secondly,according to the WAA operalor, Maximize the stage weighting model to obtain the integrated cumulative prospect value. Finally, on the basis of this, the alternatives are sorted according to the size of the total cumulative prospect value, and compared with other methods, the validity and scientific of the proposed method are proved.

Examining on assessment of English language learners

Many assessment skills are quite conducive for administering practical and effective tests and especially to ELL students. There is no perfect assessment to ELL students, and every assessment has its own limitations. The testing scores are influenced by a wide range of factors, such as the level of effort, study habits, the learning atmosphere, and physical state and so on. Therefore, self-concept and academic achievement are highly correlated.

Design of Human Resource Performance Evaluation System for Construction Enterprises

Based on job analysis for the permanent departments of construction enterprises, by combining KPI assessment method and 360-degree evaluation method, this article establishes a set of human resource performance evaluation indicator system; by determining indicators＇ weights and evaluators＇ grading weights through analytic hierarchy process （AHP）, offering a kind of dynamic computing method for performance evaluation, and tightly linking the evaluation result to employees＇ personal interests, this article builds up a set of scientific performance evaluation system. This article takes the engineering department of construction enterprises for example to explain the calculation and application of performance evaluation result. This article provides construction enterprises with a method reference for human resource performance evaluation.

Favela’s Houses as Design Reference： Using Shape Grammar

Shape grammar has been used by many researchers to identify and/or define languages in architectural design. This paper presents a methodology developed using shape grammar to analyze the informal city, specifically Favela da Rocinha’s buildings, in Rio de Janeiro. The goal was finding the organizational foundations of self-built houses in an informal settlement. A methodology was developed to find composition patterns and to infer a set of rules which defines a shape grammar of Rocinha houses, allowing synthesis and analysis of low cost solutions for house designs. And above all, it highlights underlying design solutions produced empirically by inhabitants of favelas, emphasizing the diversity in favela’s architecture, and, that is also able to reflect the particular necessities of targeted population.

Selectivity of Parvalbumin B Protein Binding to Ca^(2+) and Mg^(2+) at an Ab Initio QM/MM Level Using the Reference-Potential Method

Ion selectivity in protein binding sites is of great significance to biological functions.Although additive force fields have been successfully applied to various protein-related studies,it is difficult to well capture the subtle metal-protein interaction for the prediction of ion selectivity,due to the remarkable polarization and charge transfer effect between the metals and the surrounding residues.Quantum mechanics-based methods are well-suited for dealing with these systems,but they are too costly to apply in a direct manner.In this work,the reference-potential method(RPM)was used to measure the selectivity for calcium and magnesium cations in the binding pocket of parvalbumin B protein by calculating the free energy change associated with this substitution reaction at an ab initio quantum mechanics/molecular mechanics(QM/MM)level.The alchemical transformations were performed at the molecular mechanics level,and the relative binding free energy was then corrected to the QM/MM level via thermodynamic perturbation.In this way,the free energy change at the QM/MM level for the substitution reaction was obtained without running the QM/MM simulations,thus remarkably enhancing the efficiency.In the reweighting process,we found that the selection of the QM region greatly affects the accuracy of the QM/MM method.In particular,the charge transfer effect on the free energy change of a reaction cannot be neglected.

Adaptive Spatial-division Split-step Fourier Migration Method

This paper presents a new depth migration method, adaptive spatial-division split-step Fourier （ASDSSF） migration. In this method we introduce the idea of a stratified phase shift migration into the split-step Fourier （SSF） migration to make an accurate and efficient wave field image when sharp discontinuities appear in the velocity field. In principle, the ASDSSF migration is a multi-reference slowness （reciprocal of velocity） （MRS） migration. Compared to previous MRS migration methods, this method uses fewer reference slowness values without accuracy loss. The reference slowness is determined in this paper according to an error-control parameter of the perturbation term in the SSF operator and the variation of the complet velocity field. The velocity corresponded to reference slowness can define a spatial division. Each division can also be divided into several discontinuous spatial subdivisions to effectively reduce the number of reference slowness values needed. The choice of reference slowness, including the number of reference slowness values needed and how to construct the spatial divisions, is adaptive and reasonable at each extrapolation step （depth step）. A simple and economical smoothing filter in the wave number-frequency domain is designed to avoid artifacts in the wave field extrapolation due to the presence of sharp discontinuities in the velocity field. For comparable conditions the present approach to migration is expected to be computationally more efficient and accurate than other MRS migration methods. The performance of the method is demonstrated on a simple 2D prestack model and the prestack SEG/EAEG salt dataset.