“活动单”引导下的高职数学小组合作教学模式的应用

在高职数学教学中,用"活动单"引导学生小组合作,客观的看待活动单引导下小组合作学习中存在的问题,建立并优化教学模式,提高小组合作效果。

用“活动单”指导高中历史课堂教学

＂活动单＂是教师精心设计的供学生在课堂上使用、借以实现学生学习目标的一个方案。通过＂活动单＂导学,可以有效提高学生主动学习、合作探究和认识感悟的能力。

物理“活动单”导学模式初步探究

我们常说：“教学有法而无定法”。所谓“教学有法”中的“法”是有标准的：能最大限度地激发学生学习的主动性、自觉性和积极性，就是最佳的“法”。至于“无定法”是由于教者的素质思想不同，教材的内容不同，教学的对象不同，所以，不可能有通用的教学模式。

浅谈实施“活动单”导学模式的一点收获

根据学区领导安排，我学区教师要尝试用“活动单”导学模式进行教学，初步接触心中有些惶恐，有些茫然不知所措。数学学科一向给人的感觉都是枯燥乏味的，那么新课堂模式下的数学教学又将会是怎样的一种情景呢？“活动单”导学模式又将会给数学教学带来怎样的效应呢？教师由原先的课堂主导者变为引领者，培养学生的自主学习习惯，培养学生的合作与交流能力，关注学生能力的培养，给教学带来了清新的空气。但学生主体地位的确立是通过教师的主导作用来实现的，教学中教师的激发作用、启迪作用、组织作用和熏陶作用是学生主动学习的重要前提，因此教师的角色转换是关键。简言之，在新教材的实施过程中，给我最大的感受是相辅相成的改变，即：教师的角色改变了，学生的学习方式改变了，对学生的评价方式也改变了。

活动单--让语文课堂充满绿色

“活动单”导学是近年来在各地教学实践中得到广泛推广的一种新的教学模式，本文结合具体的教学实践。对这一教学模式的意义及操作程序作了较为深入的分析论述。

浅谈“活动单”导学模式下初中物理实验教学

＂活动单＂导学是指以＂活动单＂为媒介引导学生在＂活动＂中自主、合作学习,实现教学目标的过程。物理学是一门以实验为基础的科学,物理实验是研究物理学的重要方法和手段。应用＂活动单＂导学模式加强实验教学,有利于培养学生学习物理兴趣和具有初步观察事物、分析问题、解决问题能力。

“活动单导学”模式在体育课中的应用

“活动单导学”是指以“活动单”为媒介引导学生自主、合作学习，记录学生过程与结果，分析得出结论并自我反馈的“菜单”化设计。体育课采用“活动单”教学具有很多优点，让学生在“活动单”的引领下去探究、去有目的有方向地锻炼，让体育课也具有实效性。在体育课堂的各个环节贯串“有目的的活动”的思想、贯串期待的心理，体育课，让学生想到的不再是只是无聊地在那儿随便玩玩而已。

刍议如何使历史“活动单”具有历史性

历史"活动单"导学能够有效的调动学生的学习积极性,提高历史教学效果。在"活动单"制作过程中存在种种问题。本文以2016人教版第16课《三国鼎立》一课课堂教学片段为例,讨论历史"活动单"研制过程中如何体现历史性。历史"活动单"要体现历史的时序性和空间概念,体现历史思维在学习过程中的作用。

加强活动单教学提高学生英语交际才能

英语学习的目的是能够用英语进行交流，然而我们没有说英语的自然环境，课堂教学中学生的交际能力的培养就显得尤为重要。“活动单”导学模式是辅助教学的手段之一，在“活动单”导学模式下，可以有目的、有计划地实施课堂教学活动，实行高效教学，提高学生英语交际才能。

以“活动单导学”来提高数学复习课有效性的策略

"活动单导学"是一种有效的教学方式,以此法进行数学复习需要考虑学生的基础、能力、差异和课堂中的评价等各种因素,真正做到立足"生长点"、找准"着力点"、利用"契合点"、善用"评价点",合理运用教学策略,克服各种不利因素的影响,从而提高复习的有效性。

In vitro Anti-viral Activity of the Total Alkaloids from Tripterygium hypoglaucum against Herpes Simplex Virus Type 1

Herpes simplex virus type 1 （HSV-1） is a commonly occurring human pathogen worldwide. There is an urgent need to discover and develop new alternative agents for the management of HSV-1 infection. Tripterygium hypoglaucum （level） Hutch （Celastraceae） is a traditional Chinese medicine plant with many pharmacological activities such as anti-inflammation, anti-tumor and antifertility. The usual medicinal part is the roots which contain about a 1% yield of alkaloids. A crude total alkaloids extract was prepared from the roots of T. hypoglaucum amd its antiviral activity against HSV-1 in Vero cells was evaluated by cytopathic effect （CPE） assay, plaque reduction assay and by RT-PCR analysis. The alkaloids extract presented low cytotoxicity （CC50 = 46.6μg/mL） and potent CPE inhibition activity, the 50% inhibitory concentration （ICs0） was 6.5 μg/mL, noticeably lower than that of Acyclovir （15.4μg /mL）. Plaque formation was significantly reduced by the alkaloids extract at concentrations of 6.25 μg/mL to 12.5 μg/mL, the plaque reduction ratio reached 55% to 75% which was 35% higher than that of Acyclovir at the same concentration. RT-PCR analysis showed that, the transcription of two important delayed early genes UL30 and UL39, and a late gene US6 of HSV-1 genome all were suppressed by the alkaloids extract, the expression inhibiting efficacy compared to the control was 74.6% （UL30）, 70.9% （UL39） and 62.6% （US6） respectively at the working concentration of 12.5μg/mL. The above results suggest a potent anti-HSV-1 activity of the alkaloids extract in vitro.

浅谈幼儿园“活动单导向”模式下的语文教学

随着人们对幼儿教育事业的关注越来越大,不断的创新幼儿园的教学方式,改变传统的教学模式,激发幼儿的兴趣,实现有效性的教学成为当务之急。"活动单导向"教学模式的落实,为幼儿园教学打开了新的天地。其是一种以活动单作为学案,活动作为载体,学生作为中心,教师作为主导,合作学习为主要形式的全新教学方式,对幼儿综合素质的培养有着重要意义。

Effect of moving baffle on average velocity and mixing of binary particles in rotating drums

Adding a moving baffle to the drum is a new way to enhance the motion and mixing of particles in rotating drums.To obtain its influence on binary particles,horizontal rotating drums provided with a moving baffle were investigated by discrete element method(DEM).AtΩ=15 r/min,increasing the length of moving baffle can increase the fluctuation amplitude of average particle velocity.AtΩ=60 r/min,the influence of the moving baffle on the average velocity fluctuation tends to be more random.At both rotational speeds,the moving baffle causes the average particle velocity to fluctuate more sharply.The moving baffle can enhance particle mixing.AtΩ=15 r/min,the moving baffle with length ofδ=1/3 can best enhance particle mixing.However,atΩ=60 r/min,only the moving baffle with a specific length(δ=1/4)can enhance mixing.This basic research has a positive reference value for the application of the moving baffle in industry.

Unsteady Motion of a Single Droplet in Surfactant Solutions

A numerical investigation of the unsteady motion of a deformed drop released freely in another quiescent liquid contaminated by surfactant is presented in this paper. The finite difference method was used to solve numerically the coupled time-dependent Navier-Stokes and convective-diffusion equations in a body-fitted orthogonal coordinate system. Numerical simulation was conducted on the experimental cases, in which MIBK drops with the size ranging from 1.24 mm to 1.97 mm rose and accelerated freely in pure water and in dilute sodium dodecyl sulphate (SDS) aqueous solution. The applicability of the numerical scheme was validated by the agreement between the simulation results and the experimental data. Both the numerical and experimental results showed that the velocitytime profile exhibited a maximum rising velocity for drops in SDS solutions, which was close to the terminal velocity in pure water, before it dropped down to a steady-state value. The effect of the sorption kinetics of surfactant on the accelerating motion was also evaluated. It is also suggested that introduction of virtual mass force into the formulation improved obviously the precision of numerical simulation of transient drop motion.

Forecasting Orders with ARMA in Household Electric Appliance Enterprises Based on Mobile Agent

Forecasting orders accurately plays a crucial role for household electric appliance (HEA) enterprises keeping low inventory level. In order to reduce the influence of bullwhip effect, sales data are applied to forecast orders of the next period instead of ordering data. Mobile agent is applied to achieve the sales data from retailers in the data preparation. And the converting approach from sales data of retailers to prediction data is proposed. Autoregressive and moving average (ARMA) model is introduced to forecast orders and a comparison amongst final prediction error (FPE), Akaike information criterion(AIC), Bayes information criterion(BIC) and Akaike's corrected information criterion(AICC) criterion is shown. The sample test verifies the superiority of AICC; therefore it is applied to identify ARMA order. Forecasting architecture is established and then the prototype system is tested, at last a case shows the orders prediction of the next quarter and verifies the effectiveness of the proposed method.

Nomenclature for lunar features at the Chang＇e-3 landing site

Nomenclatures for lunar features always accompany the progresses of human lunar exploration,which has an important dual meaning in culture and science. The naming of lunar features not only can commemorate the outstanding contributions of academics,masters in various fields, and popularize the traditional cultures of ethnic groups all over the world, but also have a critical function of providing accurate indicative information on features with special morphology, origin, nature and scientific value. However, nomenclature for features at the Chang'e-3 landing site, which has a more arbitrary form without many constrains posed by a uniformed system, is unlike the features for other morphological units.This paper originated from the actual needs for the description of scientific exploration activities, interpretation of scientific research and dissemination of scientific results. Some prominent morphological units with great scientific importance and identification purpose were chosen from the images taken by the terrain camera, panorama cameras and landing camera onboard the Chang'e lander and Yutu rover. A nomenclature system was established under the three enclosures, four quadrants and twenty-eight lunar lodges' system of the Chinese ancient sky division method. Finally, a standard feature names set waspublished after some necessary approval procedures by the International Astronomical Union.

Comparative studies on storage cells in tardigrades during starvation and anhydrobiosis

The impact of starvation and anhydrobiosis on the number and size of the storage cells in the tardigrade species Milnesium tardigradum, Paramacrobiotus tonollii and Macrobiotus sapiens was investigated to gain more insight on the energetic side of anhydrobiosis. Storage cells are free floating cells within the body cavity of tardigrades and are presumed to store and release energy in form of glycogen, protein and fat to maintain a constant nutrient regime for the other tissues. The body size of the animals was not correlated with the size of the storage cells, however, M. tardigradum the largest species analysed also had the largest storage cells. A reduction in the size of the storage cells is apparent in all three species after seven days of starvation. A seven-day period of anhydrobiosis leads to a decrease in cell size in M. tardigradum but not in P. tonollii and M. sapiens. Although M. sapiens was raised on green algae, and M. tardigradum and P. tonollii were fed with rotifers and nematodes this difference in nourishment was not reflected in the response of the storage cells to anhydrobiosis

Extraprofessional and Occupational Risk Factors for Colorectal Cancer

Colorectal cancers （CRC） account for frequent and serious cancers which result from the interaction between individual genetic factors and environmental factors, and in particular widely studied nutritional ones. The role of other occupational factors remains a controversial subject. The objective of this study is to evaluate the possible impact of occupational factors on the risk of developing CRC. Materials and Methods： This is a retrospective case-control study. The cases and the control group were enlisted in the general surgical ward of Farhat Hached Teaching Hospital of Sousse （Tunisia） during the period extending from 2004 to 2008, and they were age and gender-matched. The data were analyzed using SPSS 11.0 software with a signification threshold fixed at 5%. A univariate analysis was carried out as well as a multiple binary logistical regression. Results： During the period of the study, 40 cases of colorectal cancers have been colligated including 28 men and 12 women with a sex ratio of 0.43. The average age of the cases was 61.55 ± 13.3 years and 60.40 ± 12.84 years for the control group, with a non significant difference （P = 0.69）. The univariate analysis has objectivized significant associations between colorectal cancer and the housing conditions, the neoplastic and digestive family history, the occupational activity sector, exposure to pesticides, and lack of periodic medical supervision. After logistical regression, the occurrence risk of CRC was significantly associated with： alcohol and smoking （ORa = 3.43; Pa = 0.05）, meat consumption （ORa = 3.34; Pa = 0.03）, exposure to pesticides （ORa = 20.44; Pa = 0.012） and lack of periodic medical supervision （OR = 7.45; P = 0.004）. Conclusion： The occupational risk factors might play a role in the etiopathogenesis of colorectal cancers. With regard to our study, pesticides seem to be most implicated and necessitate suitable preventive measures. Nevertheless, it seems useful to multiply the studies to a much larger scale in order to further explore such relationship and to further reinforce the prevention of such serious disease.

Cilostazol inhibits plasmacytoid dendritic cell activation and antigen presentation

Background Cilostazol, an anti-platelet drug for treating coronary heart disease, has been reported to modulate immune cell functions Plasmacytoid dendritic cells （pDCs） have been found to participate in the progression of atherosclerosis mainly through interferon ct （IFN-ct） production. Whether cilostazol influences pDCs activation is still not clear. In this study, we aimed to investigate the effects of cilostazol on cell activation and antigen presentation ofpDCs in vitro in this study. Methods Peripheral blood mononuclear cells isolated by Ficoll cen- trifugation and pDCs sorted by flow cytometry were used in this study. After pretreated with cilostazol for 2 h, cells were stimulated with CpG-A, R848 or virus for 6 h or 20 h, or stimulated with CpG-B for 48 h and then co-cultured with naive T cell for five days. Cytokines in supernatant and intracellular cytokines were analyzed by ELISA or flow cytometry respectively. Results Our data indicated that cilostazol could inhibit IFN-α and tumor necrosis factor α （TNF-α） production from pDCs in a dose-dependent manner. In addition, the ability of priming na ve T cells of pDCs was also impaired by cilostazol. The inhibitory effect was not due to cell killing since the viability of pDCs did not change upon cilostazol treatment. Conclusion Cilostazol inhibits pDCs cell activation and antigen presentation in vitro, which may explain how cilostazol protects against atherosclerosis.

Increased Activity of the Human Telomerase Catalytic Subunit Promoter by the VEGF Enhancer in Human Cancer Cells

We attempted to improve the activity of hTERT promoter by fusing the vascular endothelial growth factor （VEGF） enhancer. To determine the potential as cancer specific promoters, we measured the reporter gene transfection assay driven by the hTERT promoter and the VEGF enhancer in human cancer cells. We found that the hTERT promoter containing VEGF enhancer conferred strong expression of the reporter gene only in different cancer cell lines but not in normal human cells. Retrovirus vector expressing HSV-TK controlled by the hTERT promoter and the VEGF enhancer was constructed. A549 cells infected with LN-enh-hT-TK was significantly suppressed and induced to apoptosis more than those infected with LN-hT-TK. The apoptosis ratio ofA549 cell infected with two kinds of retrovirus cell with GCV in lower concentration is 20.94% and 50.7%. It suggested that there is significant differentiation between the assay groups. Our results demonstrated the possible application of hTERT promoter and the VEGF enhancer in targeted cancer gene therapy.